Histomorphometric analysis and markers of endometrial receptivity embryonic implantation in women with polycystic ovary syndrome during the treatment with progesterone

Reproductive Sciences

Volumn 21, Issue 7, 2014, Pages 930-938

  Lopes, Ione Maria Ribeiro Soares ^a   Maganhin, Carla Cristina ^b   Oliveira Filho, Ricardo Martins ^c   Simões, Ricardo Santos ^c   Simões, Manuel Jesus ^b   Iwata, Margareth Chiharu ^b   Baracat, Edmund Chada ^c   Soares, José Maria ^b,c  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

cell adhesion molecules; endometrium; polycystic ovary syndrome

Indexed keywords

INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; PROGESTERONE; UVOMORULIN;

ADULT; ARTICLE; BODY MASS; CASE CONTROL STUDY; CONTROLLED STUDY; ENDOMETRIUM; ENDOMETRIUM BIOPSY; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MORPHOMETRICS; NIDATION; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROSPECTIVE STUDY; PROTEIN EXPRESSION;

EID: 84904651254     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719113519169     Document Type: Article

References (38)

1. Lopes IM, Baracat MC, Simões M de J, Simões RS, Baracat EC, Soares JM. Endometrium in women with polycystic ovary syndrome during the window of implantation. Rev Assoc Med Bras. 2011 ; 57 (6). 702-709
2. Bart CJ, Fauser BC, Tarlatzis BC, et al. Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3 rd PCOS consensus workshop group. Fertil Steril. 2012 ; 97 (1). 38-63
3. Lujan ME, Jarrett BY, Brooks ED, et al. Updated ultrasound criteria for polycystic ovary syndrome: reliable thresholds for elevated follicle population and ovarian volume. Hum Reprod. 2013 ; 28 (5). 1361-1368
4. Dumesic DA, Padmanabhan V, Abbott DH. Polycystic ovary syndrome and oocyte developmental competence. Obstet Gynecol Surv. 2008 ; 63 (1). 39-48
5. Shang K, Jia X, Qiao J, Kang J, Guan Y. Endometrial abnormality in women with polycystic ovary syndrome. Reprod Sci. 2012 ; 19 (7). 674-683
6. Cakmak H, Taylor HS. Human implantation failure: molecular mechanisms and clinical treatment. Hum Reprod Update. 2011 ; 17 (2). 242-253
7. Quezada S, Avellaira C, Johnson MC, Gabler F, Fuentes A, Vega M. Evaluation of steroid receptors, coregulators, and molecules associated with uterine receptivity in secretory endometria from untreated women with polycystic ovary syndrome. Fertil Steril. 2006 ; 85 (4). 1017-1026
8. Donaghay M, Lessey BA. Uterine receptivity: alterations associated with benign gynecological disease. Semin Reprod Med. 2007 ; 25 (6). 461-475
9. Lai TH, Shih IM, Vlahos N, Ho CL, Wallach E, Zhao Y. Differential expression of L-selectin ligand in the endometrium during the menstrual cycle. Fertil Steril. 2005 ; 83 (suppl 1). 1297-1302
10. Lessey BA. Assessment of endometrial receptivity. Fertil Steril. 2011 ; 96 (3). 522-529
11. DuQuesnay R, Wright C, Aziz AA, et al. Infertile women with isolated polycystic ovaries are deficient in endometrial expression of osteopontin but not alphavbeta3 integrin during the implantation window. Fertil Steril. 2009 ; 91 (2). 489-499
12. Smalley DM, Ley K. L-selectin: mechanisms and physiological significance of ectodomain cleavage. J Cell Mol Med. 2005 ; 9 (2). 255-266
13. Margarit L, Taylor A, Roberts MH, et al. MUC1 as a discriminator between endometrium from fertile and infertile patients with PCOS and endometriosis. J Clin Endocrinol Metab. 2010 ; 95 (12). 5320-5329
14. Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update. 2006 ; 12 (6). 731-746
15. Solano ME, Sander VA, Ho H, Motta AB, Arck PC. Systemic inflammation, cellular influx and up-regulation of ovarian VCAM-1 expression in a mouse model of polycystic ovary syndrome (PCOS). J Reprod Immunol. 2011 ; 92 (1-2). 33-44
16. Bayram F, Kocer D, Ozsan M, Muhtaroglu S. Evaluation of endothelial dysfunction, lipid metabolism in women with polycystic ovary syndrome: relationship of paraoxonase 1 activity, malondialdehyde levels, low-density lipoprotein subfractions, and endothelial dysfunction. Gynecol Endocrinol. 2012 ; 28 (7). 497-501
17. Vural P, Kanmaz-Özer M, Doru-Abbasolu S, et al. Lack of association between intercellular adhesion molecule-1 (ICAM-1) polymorphisms and polycystic ovary syndrome. J Assist Reprod Genet. 2011 ; 28 (9). 869-875
18. Azziz R, Carmina E, Dewailly D, et al. The androgen excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril. 2009 ; 91 (2). 456-488
19. Sharma D, Shanker V, Tegta G, Gupta M, Verma GK. Clinico-investigative Profile of Patients of Hirsutism in a Tertiary Level Institution. Int J Trichology. 2012 ; 4 (2). 69-74
20. Panzan MQ, Mattar R, Maganhin CC, et al. Evaluation of FAS and caspase-3 in the endometrial tissue of patients with idiopathic infertility and recurrent pregnancy loss. Eur J Obstet Gynecol Reprod Biol. 2013 ; 167 (1). 47-52
21. Gonzalez RR, Palomino A, Vantman D, Gabler F, Devoto L. Abnormal pattern of integrin expression at the implantation window in endometrium from fertile women treated with clomiphene citrate and users of intrauterine device. Early Pregnancy. 2001 ; 5 (2). 132-143
22. Schoolcraft WB, Hesla JS, Gee MJ. Experience with progesterone gel for luteal support in a highly successful IVF programme. Hum Reprod. 2000 ; 15 (6). 1284-1288
23. Ganesh A, Chakravorty N, Mukherjee R, Goswami S, Chaudhury K, Chakravarty B. Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study. Fertil Steril. 2011 ; 95 (6). 1961-1965
24. Nahid L, Sirous K. Comparison of the effects of letrozole and clomiphene citrate for ovulation induction in infertile women with polycystic ovary syndrome. Minerva Ginecol. 2012 ; 64 (3). 253-258
25. Lessey BA, Damjanovich L, Coutifaris C, Castelbaum A, Albelda SM, Buck CA. Correlation with the normal and abnormal menstrual cycle. J Clin Invest. 1992 ; 90 (1). 188-195
26. Reddy KV, Mangale SS. Integrin receptors: the dynamic modulators of endometrial function. Tissue Cell. 2003 ; 35 (4). 260-273
27. Savaris RF, Groll JM, Young SL, et al. Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. J Clin Endocrinol Metab. 2011 ; 96 (6). 1737-1746
28. Lai TH, Zhao Y, Shih IeM, Ho CL, Bankowski B, Vlahos N. Expression of L-selectin ligands in human endometrium during the implantation window after controlled ovarian stimulation for oocyte donation. Fertil Steril. 2006 ; 85 (3). 761-763
29. Lacin S, Vatansever S, Kuscu NK, Koyuncu F, Ozbilgin K, Ceylan E. Clomiphene citrate does not affect the secretion of alpha3, alphaV and beta1 integrin molecules during the implantation window in patients with unexplained infertility. Hum Reprod. 2001 ; 16 (11). 2305-2309
30. Kilic S, Hatipoglu T, Erdogan D, et al. Impact of high levels of progesterone on alpha(1)-integrin distribution in the endometrium of patients with unexplained infertility. Acta Histochem. 2008 ; 110 (5). 363-370
31. Casals G, Ordi J, Creus M, et al. Osteopontin and alphavbeta3 integrin as markers of endometrial receptivity: the effect of different hormone therapies. Reprod Biomed Online. 2010 ; 21 (3). 349-359
32. Sillem M, Prifti S, Schmidt M, Rabe T, Runnebaum B. Endometrial integrin expression is independent of estrogen or progestin treatment in vitro. Fertil Steril. 1997 ; 67 (5). 877-882
33. Apparao KB, Lovely LP, Gui Y, Lininger RA, Lessey BA. Elevated endometrial androgen receptor expression in women with polycystic ovarian syndrome. Biol Reprod. 2002 ; 66 (2). 297-304
34. Lessey BA, Arnold JT. Paracrine signaling in the endometrium: integrins and the establishment of uterine receptivity. J Reprod Immunol. 1998 ; 39 (1-2). 105-116
35. Musso C, Cochran E, Moran SA, et al. Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective. Medicine. 2004 ; 83 (4). 209-222
36. Foulk RA, Zdravkovic T, Genbacev O, Prakobphol A. Expression of L-selectin ligand MECA-79 as a predictive marker of human uterine receptivity. J Assist Reprod Genet. 2007 ; 24 (7). 316-321
37. Baghdadi LR, Abu Hashim H, Amer SA, et al. Impact of obesity on reproductive outcomes after ovarian ablative therapy in PCOS: a collaborative meta-analysis. Reprod Biomed Online. 2012 ; 25 (3). 227-241
38. Aplin JD, Singh H. Bioinformatics and transcriptomics studies of early implantation. Ann N Y Acad Sci. 2008 ; 1127: 116-120