Different design of enzyme-triggered CO-releasing molecules (ET-CORMs) reveals quantitative differences in biological activities in terms of toxicity and inflammation

Redox Biology

Volumn 2, Issue 1, 2014, Pages 739-748

  Stamellou, E ^a,b   Storz, D ^a,b   Botov, S ^c   Ntasis, E ^b   Wedel, J ^b   Sollazzo, S ^c   Kramer B K ^b   van Son, W ^d   Seelen, M ^d   Schmalz, H G ^c   Schmidt, A ^c   Hafner, M ^a   Yard, B A ^b  

^a MANNHEIM UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Adhesion molecules; Carbon monoxide; Endothelial cells; Enzyme triggered CORMs

Indexed keywords

2 CYCLOHEXENONE; ADENOSINE TRIPHOSPHATE; CARBON MONOXIDE; CHEMICAL COMPOUND; CYCLODEXTRIN; DIMETHYL SULFOXIDE; ENZYME TRIGGERED CARBON MONOXIDE RELEASING MOLECULE; FERROUS CHLORIDE; HEME OXYGENASE 1; I KAPPA B ALPHA; IRON; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; COORDINATION COMPOUND; CYCLOHEXANONE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRON DERIVATIVE; NFE2L2 PROTEIN, HUMAN;

ARTICLE; BIOLOGICAL ACTIVITY; CELL DEATH; CELL RESPIRATION; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; HUMAN; HUMAN CELL; INFLAMMATION; IRON CHELATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; STRUCTURE ACTIVITY RELATION; UMBILICAL VEIN ENDOTHELIAL CELL; APOPTOSIS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TOXICITY;

APOPTOSIS; CARBON MONOXIDE; COORDINATION COMPLEXES; CYCLOHEXANONES; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; IRON COMPOUNDS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84904595783     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2014.06.002     Document Type: Article

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