Challenges for molecular diagnosis of familial early-onset diabetes in unexplored populations

Iranian Journal of Public Health

Volumn 43, Issue 7, 2014, Pages 1011-1013

  Amara, Abdelbasset ^a,b,c   Chadli Chaieb, Molka ^a,b   Chaieb, Larbi ^b   Saad, Ali ^b   Gribaa, Moez ^b  

^a UNIVERSITY OF SOUSSE   (Tunisia)

^b FARHAT HACHED HOSPITAL   (Tunisia)

^c UNIVERSITY OF MONASTIR   (Tunisia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84904573587     PISSN: 22516085     EISSN: 22516093     Source Type: Journal    
DOI: None     Document Type: Letter

References (8)

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2. Bonnefond A, Philippe J, Durand E, Dechaume A, Huyvaert M, Montagne L, Marre M, Balkau B, Fajardy I, Vambergue A, Vatin V, Delplanque J, Le Guilcher D, De Graeve F, Lecoeur C, Sand O, Vaxillaire M, Froguel P (2012). Whole-Exome Sequencing and High Throughput Genotyping Identified KCNJ11 as the Thirteenth MODY Gene. PLoS One, 7:e37423.
3. Amara A, Chadli-Chaieb M, Ghezaiel H, Philippe J, Brahem R, Dechaume A, Saad A, Chaieb L, Froguel P, Gribaa M, Vaxillaire M (2012). Familial early-onset diabetes is not a typical MODY in several Tunisian patients. Tunis Med, 90:882-887.
4. Plengvidhya N, Kooptiwut S, Songtawee N, Doi A, Furuta H, Nishi M, Nanjo K, Tantibhedhyangkul W, Boonyasrisawat W, Yenchitsomanus PT, Doria A, Banchuin N (2007). PAX4 mutations in Thais with maturity onset diabetes of the young. J Clin Endocrinol Metab, 92:2821-2826.
5. Jo W, Endo M, Ishizu K, Nakamura A, Tajima T (2011). A novel PAX4 mutation in a Japanese patient with maturity-onset diabetes of the young. Tohoku J Exp Med, 223:113-118.
6. Pearl EJ, Horb ME (2008). Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies. Clin Genet, 74:316-324.
7. Bonnefond A, Philippe J, Durand E et al. (2013). Highly sensitive diagnosis of 43 monogenic forms of diabetes or obesity, through one step PCR-based enrichment in combination with next-generation sequencing. Diabetes Care, 2014 Feb;37(2):460-467.
8. Ellard S, Lango Allen H, De Franco E, Flanagan SE, Hysenaj G, Colclough K, Houghton JA, Shepherd M, Hattersley AT, Weedon MN, Caswell R (2013). Improved genetic testing for monogenic diabetes using targeted next-generation sequencing. Diabetologia, 56:1958-1963.