Discovery of multifold modified sialosides as Human CD22/Siglec-2 ligands with nanomolar activity on B-cells

ACS Chemical Biology

Volumn 9, Issue 7, 2014, Pages 1444-1450

  Prescher, Horst ^a   Schweizer, Astrid ^b   Kuhfeldt, Elena ^a   Nitschke, Lars ^b   Brossmer, Reinhard ^c  

^a G3 BioTec   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD22 ANTIGEN; ESTER; ETHER; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; SIALOSIDE DERIVATIVE; UNCLASSIFIED DRUG; IMMUNOLOGIC FACTOR; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; N ACETYLNEURAMINIC ACID;

ARTICLE; B LYMPHOCYTE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; SYNTHESIS; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; IMMUNOLOGY;

B-LYMPHOCYTES; CELL LINE; DRUG DISCOVERY; HUMANS; IMMUNOLOGIC FACTORS; LIGANDS; N-ACETYLNEURAMINIC ACID; RECEPTORS, ANTIGEN, B-CELL; SIALIC ACID BINDING IG-LIKE LECTIN 2;

EID: 84904572305     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400952v     Document Type: Article

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