Colonization and Infection due to Multi-resistant Bacteria in Neonates: A Single Center Analysis

Klinische Padiatrie

Volumn 226, Issue 1, 2014, Pages 8-12

  Haase, R ^a   Worlitzsch, D ^a   Schmidt, F ^a   Kulka, R ^a   Kekule A S ^a   Korholz D ^a  

^a MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

Author keywords

colonization; multiresistant bacteria; neonatal infection; neonate

Indexed keywords

ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL COLONIZATION; BACTERIUM; BACTERIUM DETECTION; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; GRAM NEGATIVE BACTERIUM; HUMAN; HYGIENE; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTI RESISTANT PATHOGEN; NEWBORN; NEWBORN INFECTION; NEWBORN INTENSIVE CARE; NONHUMAN; RETROSPECTIVE STUDY; RISK FACTOR; SEPSIS; VANCOMYCIN RESISTANT ENTEROCOCCUS; BIRTH WEIGHT; CROSS INFECTION; CROSS-SECTIONAL STUDY; GERMANY; GRAM NEGATIVE INFECTION; MICROBIOLOGY; MULTIDRUG RESISTANCE; PREMATURITY; VERY LOW BIRTH WEIGHT;

ANTIINFECTIVE AGENT;

ANTI-BACTERIAL AGENTS; BIRTH WEIGHT; CROSS INFECTION; CROSS-SECTIONAL STUDIES; DRUG RESISTANCE, MULTIPLE; FEMALE; GERMANY; GESTATIONAL AGE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; INTENSIVE CARE UNITS, NEONATAL; MALE; RESPIRATION, ARTIFICIAL; RISK FACTORS; SEPSIS;

EID: 84904560710     PISSN: 03008630     EISSN: 14393824     Source Type: Journal    
DOI: 10.1055/s-0033-1354376     Document Type: Article

References (28)

1. Aly H., Herson V., Duncan A. et al. Is bloodstream infection preventable among premature infants? A tale of two cities. Pediatrics: 2005; 115 1513 1518
2. Benenson S., Levin P. D., Block C. et al. Continuous surveillance to reduce extended-spectrum beta-lactamase Klebsiella pneumoniae colonization in the neonatal intensive care unit. Neonatology: 2013; 103 155 160
3. Bersani I., Speer C. P. Nosocomial sepsis in neonatal intensive care: inevitable or preventable? Z Geburtshilfe Neonatol: 2012; 216 186 190
4. Crivaro V., Bagattini M., Salza M. F. et al. Risk factors for extended-spectrum beta-lactamase-producing Serratia marcescens and Klebsiella pneumoniae acquisition in a neonatal intensive care unit. J Hosp Infect: 2007; 67 135 141
5. Curry S., Honeycutt M., Goins G. et al. Catheter-associated bloodstream infections in the NICU: getting to zero. Neonatal Netw: 2009; 28 151 155
6. ECDC. European Centre for Disease Prevention and Control Summary of the latest data on antibiotic resistance in the European Union: 2012; Access date: 22.01.2013 Http://ecdc.europa.eu/en/eaad/Documents/EARS-Net-summary-antibiotic-resistance.pdf
7. Gagliotti C., Balode A., Baquero F. et al. Escherichia coli and Staphylococcus aureus: bad news and good news from the European Antimicrobial Resistance Surveillance Network (EARS-Net, formerly EARSS), 2002 to 2009. Euro Surveill: 2011; 16
8. Gastmeier P., Loui A., Stamm-Balderjahn S. et al. Outbreaks in neonatal intensive care units - they are not like others. Am J Infect Control: 2007; 35 172 176
9. Geffers C., Gastmeier P. Nosocomial infections and multidrug-resistant organisms in Germany: epidemiological data from KISS (the Hospital Infection Surveillance System). Dtsch Arztebl Int: 2011; 108 87 93
10. Giuffre M., Cipolla D., Bonura C. et al. Outbreak of colonizations by extended-spectrum beta-lactamase-producing Escherichia coli sequence type 131 in a neonatal intensive care unit, Italy. Antimicrob Resist Infect Control: 2013; 2 8
11. Gortner L. Nosocomial infections in Very preterm neonates - Improvements by further scientific research or discussions in talk shows? Klin Padiatr: 2013; 225 55 56
12. Hartel C., Faust K., Avenarius S. et al. Epidemic microclusters of blood-culture proven sepsis in very-low-birth weight infants: experience of the German Neonatal Network. PLoS One: 2012; 7 e38304
13. Heinrich N., Mueller A., Bartmann P. et al. Successful management of an MRSA outbreak in a neonatal intensive care unit. Eur J Clin Microbiol Infect Dis: 2011; 30 909 913
14. Kohlenberg A., Schwab F., Meyer E. et al. Regional trends in multidrug-resistant infections in German intensive care units: a real-time model for epidemiological monitoring and analysis. J Hosp Infect: 2009; 73 239 245
15. KRINKO Empfehlungen zur Prävention nosokomialer Infektionen bei neonatologischen Intensivpflegepatienten mit einem Geburstgewicht unter 1 500 g. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz: 2007; 50 1265 1303
16. KRINKO Definition der Multiresistenz gegenüber Antibiotika bei gramnegativen Stäbchen im Hinblick auf Maβnahmen zur Vermeidung der Weiterverbreitung. Epidemiologisches Bulletin: 2012; 337 339
17. KRINKO Ergänzende Empfehlung zur »Prävention nosokomialer Infektionen bei neonatologischen Intensivpatienten mit einem Geburtsgewicht unter 1 500 g. Epidemiol Bull: 2012; 13 15
18. KRINKO Hygienemaβnahmen bei Infektionen oder Besiedlung mit multiresistenten gramnegativen Stäbchen. Bundesgesundheitsbl: 2012; 1311 1354
19. Leistner R., Piening B., Gastmeier P. et al. Nosocomial Infections in Very Low Birthweight Infants in Germany: Current Data from the National Surveillance System NEO-KISS. Klin Padiatr: 2013; 225 75 80
20. Mammina C., Di Carlo P., Cipolla D. et al. Surveillance of multidrug-resistant gram-negative bacilli in a neonatal intensive care unit: prominent role of cross transmission. Am J Infect Control: 2007; 35 222 230
21. Mattner F., Bange F. C., Meyer E. et al. Preventing the spread of multidrug-resistant gram-negative pathogens: recommendations of an expert panel of the German Society For Hygiene and Microbiology. Dtsch Arztebl Int: 2012; 109 39 45
22. Meyer E., Ziegler R., Mattner F. et al. Increase of patients co-colonised or co-infected with methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium or extended-spectrum beta-lactamase-producing Enterobacteriaceae. Infection: 2011; 39 501 506
23. Millar M., Philpott A., Wilks M. et al. Colonization and persistence of antibiotic-resistant Enterobacteriaceae strains in infants nursed in two neonatal intensive care units in East London, United Kingdom. J Clin Microbiol: 2008; 46 560 567
24. NRZ http://www.nrz-hygiene.de. Access date: 22.01.2013
25. Ruegger C., Hegglin M., Adams M. et al. Population based trends in mortality, morbidity and treatment for very preterm- and very low birth weight infants over 12 years. BMC Pediatr: 2012; 12 17
26. Simon A., Tenenbaum T. Surveillance of multidrug-resistant Gram-negative pathogens in high-risk neonates - does it make a difference? Pediatr Infect Dis J: 2013; 32 407 409
27. Stichtenoth G., Demmert M., Bohnhorst B. et al. Major contributors to hospital mortality in very-low-birth-weight infants: data of the birth year 2010 cohort of the German Neonatal Network. Klin Padiatr: 2012; 224 276 281
28. Wojkowska-Mach J., Chmielarczyk A., Borszewska-Kornacka M. et al. Enterobacteriaceae Infections of Very Low Birth Weight Infants in Polish Neonatal Intensive Care Units: Resistance and Cross-transmission. Pediatr Infect Dis J: 2013; 32 594 598