Prenatal restraint stress is associated with demethylation of corticotrophin releasing hormone (CRH) promoter and enhances CRH transcriptional responses to stress in adolescent rats

Neurochemical Research

Volumn 39, Issue 7, 2014, Pages 1193-1198

  Xu, Li ^a   Sun, Yan ^a   Gao, Lu ^a   Cai, Yi Yun ^a   Shi, Shen Xun ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Behavior; Epigenetic; HPA axis; Pregnancy; Rat; Stress

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; FEMALE; GENETIC TRANSCRIPTION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION STRESS; MALE; MATERNAL STRESS; NONHUMAN; PREGNANCY; PRENATAL PERIOD; PRENATAL STRESS; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; RAT; SPRAGUE DAWLEY RAT; ANIMAL; BIOSYNTHESIS; BLOOD; COMPLICATION; EXERCISE; MENTAL STRESS; METABOLISM; METHYLATION; PHYSIOLOGY; PRENATAL EXPOSURE; PSYCHOLOGY; RANDOMIZATION;

RATTUS;

ANIMALS; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; FEMALE; MALE; METHYLATION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROMOTER REGIONS, GENETIC; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RESTRAINT, PHYSICAL; STRESS, PSYCHOLOGICAL; TRANSCRIPTION, GENETIC;

EID: 84904552860     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1296-0     Document Type: Article

References (33)

1. Dunkel Schetter C, Tanner L (2012) Anxiety, depression and stress in pregnancy: implications for mothers, children, research, and practice. Curr Opin Psychiatry 25(2):141-148
2. Darnaudery M, Maccari S (2008) Epigenetic programming of the stress response in male and female rats by prenatal restraint stress. Brain Res Rev 57(2):571-585
3. Charil A, Laplante DP, Vaillancourt C et al (2010) Prenatal stress and brain development. Brain Res Rev 65(1):56-79
4. O'Connor TG, Bergman K, Sarkar P et al (2013) Prenatal cortisol exposure predicts infant cortisol response to acute stress. Dev Psychobiol 55(2):145-155
5. Green MK, Rani CS, Joshi A et al (2011) Prenatal stress induces long term stress vulnerability, compromising stress response systems in the brain and impairing extinction of conditioned fear after adult stress. Neuroscience 192:438-451
6. Abe H, Hidaka N, Kawagoe C et al (2007) Prenatal psychological stress causes higher emotionality, depression-like behavior, and elevated activity in the hypothalamo-pituitary-adrenal axis. Neurosci Res 59(2):145-151 (Pubitemid 47440106)
7. Davis EP, Glynn LM, Waffarn F et al (2011) Prenatal maternal stress programs infant stress regulation. J Child Psychol Psychiatry 52(2):119-129
8. Van den Bergh BR, Van Calster B, Smits T et al (2008) Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood. Neuropsychopharmacology 33(3):536-545
9. Pawluski JL, Brain UM, Underhill CM et al (2012) Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function. Psychoneuroendocrinology 37(7):1019-1028
10. Pawluski JL, Rayen I, Niessen NA et al (2012) Developmental fluoxetine exposure differentially alters central and peripheral measures of the HPA system in adolescent male and female offspring. Neuroscience 220:131-141
11. Pawluski JL (2012) Perinatal selective serotonin reuptake inhibitor exposure: impact on brain development and neural plasticity. Neuroendocrinology 95(1):39-46
12. Ansorge MS, Zhou M, Lira A et al (2004) Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science 306(5697):879-881 (Pubitemid 39446998)
13. Belay H, Burton CL, Lovic V et al (2011) Early adversity and serotonin transporter genotype interact with hippocampal glucocorticoid receptor mRNA expression, corticosterone, and behavior in adult male rats. Behav Neurosci 125(2):150-160
14. Maccari S, Morley-Fletcher S (2007) Effects of prenatal restraint stress on the hypothalamus-pituitary-adrenal axis and related behavioural and neurobiological alterations. Psychoneuroendocrinology 32(Suppl 1):S10-S15 (Pubitemid 47211641)
15. Weaver IC, Cervoni N, Champagne FA et al (2004) Epigenetic programming by maternal behavior. Nat Neurosci 7(8):847-854 (Pubitemid 38989508)
16. Weaver IC, D'Alessio AC, Brown SE et al (2007) The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J Neurosci 27(7):1756-1768 (Pubitemid 46280071)
17. Kosten TA, Huang W, Nielsen DA (2013) Sex and litter effects on anxiety and DNA methylation levels of stress and neurotrophin genes in adolescent rats. Dev Psychobiol
18. McGowan PO, Sasaki A, D'Alessio AC et al (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12(3):342-348
19. Hompes T, Izzi B, Gellens E et al (2013) Investigating the influence of maternal cortisol and emotional state during pregnancy on the DNA methylation status of the glucocorticoid receptor gene (NR3C1) promoter region in cord blood. J Psychiatr Res 47(7):880-891
20. Chen J, Evans AN, Liu Y et al (2012) Maternal deprivation in rats is associated with corticotrophin-releasing hormone (CRH) Promoter hypomethylation and enhances CRH transcriptional responses to stress in adulthood. J Neuroendocrinol 24(7):1055-1064
21. Zuena AR, Mairesse J, Casolini P et al (2008) Prenatal restraint stress generates two distinct behavioral and neurochemical profiles in male and female rats. PLoS ONE 3(5):e2170
22. Weinstock M (2008) The long-term behavioural consequences of prenatal stress. Neurosci Biobehav Rev 32(6):1073-1086
23. Maccari S, Darnaudery M, Morley-Fletcher S et al (2003) Prenatal stress and long-term consequences: implications of glucocorticoid hormones. Neurosci Biobehav Rev 27(1-2):119-127 (Pubitemid 36535394)
24. Zagron G, Weinstock M (2006) Maternal adrenal hormone secretion mediates behavioural alterations induced by prenatal stress in male and female rats. Behav Brain Res 175(2):323-328 (Pubitemid 44781115)
25. Morley-Fletcher S, Mairesse J, Soumier A et al (2011) Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats. Psychopharmacology 217(3):301-313
26. Rayen I, van den Hove DL, Prickaerts J et al (2011) Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence. PLoS ONE 6(9):e24003
27. Frye CA, Walf AA (2004) Estrogen and/or progesterone administered systemically or to the amygdala can have anxiety-, fear-, and pain-reducing effects in ovariectomized rats. Behav Neurosci 118(2):306-313 (Pubitemid 38445606)
28. Estrada-Camarena E, Fernandez-Guasti A, Lopez-Rubalcava C (2003) Antidepressant-like effect of different estrogenic compounds in the forced swimming test. Neuropsychopharmacology 28(5):830-838
29. Walf AA, Frye CA (2005) Antianxiety and antidepressive behavior produced by physiological estradiol regimen may be modulated by hypothalamic-pituitary- adrenal axis activity. Neuropsychopharmacology 30(7):1288-1301
30. Elliott E, Ezra-Nevo G, Regev L et al (2010) Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. Nat Neurosci 13(11):1351-1353
31. Mueller BR, Bale TL (2008) Sex-specific programming of offspring emotionality after stress early in pregnancy. J Neurosci 28(36):9055-9065
32. Zhang X, Odom DT, Koo SH et al (2005) Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci U S A 102(12):4459-4464 (Pubitemid 40397134)
33. Rishi V, Bhattacharya P, Chatterjee R et al (2010) CpG methylation of half-CRE sequences creates C/EBPalpha binding sites that activate some tissue-specific genes. Proc Natl Acad Sci U S A 107(47):20311-20316