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Volumn 290, Issue 2, 2014, Pages 321-328

Comparison of two oral contraceptive forms containing cyproterone acetate and drospirenone in the treatment of patients with polycystic ovary syndrome: A randomized clinical trial

Author keywords

Hirsutism; Hyperandrogenism; Insulin resistance; Oral contraceptive; Polycystic ovary syndrome

Indexed keywords

ANDROGEN; CYPROTERONE ACETATE; DROSPIRENONE; ETHINYLESTRADIOL; PRASTERONE SULFATE;

EID: 84904541540     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-014-3217-5     Document Type: Article
Times cited : (36)

References (44)
  • 3
    • 84856492535 scopus 로고    scopus 로고
    • Polycystic ovary syndrome in 2011: Genes, aging and sleep apnea in polycystic ovary syndrome
    • Dunaif A (2011) Polycystic ovary syndrome in 2011: genes, aging and sleep apnea in polycystic ovary syndrome. Nat Rev Endocrinol 20:72-74
    • (2011) Nat Rev Endocrinol , vol.20 , pp. 72-74
    • Dunaif, A.1
  • 4
    • 0034069373 scopus 로고    scopus 로고
    • Combined oral contraceptive treatment of adolescent girls with polycystic ovary syndrome. Lipid profile
    • Creatsas G, Koliopoulos C, Mastorakos G (2000) Combined oral contraceptive treatment of adolescent girls with polycystic ovary syndrome. Lipid profile. Ann N Y Acad Sci 900:245-252 (Pubitemid 30251475)
    • (2000) Annals of the New York Academy of Sciences , vol.900 , pp. 245-252
    • Creatsas, G.1    Koliopoulos, C.2    Mastorakos, G.3
  • 5
    • 15844362295 scopus 로고    scopus 로고
    • The pathophysiology of polycystic ovary syndrome: Trying to understand PCOS and its endocrinology
    • Balen A (2004) The pathophysiology of polycystic ovary syndrome: trying to understand PCOS and its endocrinology. Best Pract Res Clin Obstet Gynaecol 18:685-706
    • (2004) Best Pract Res Clin Obstet Gynaecol , vol.18 , pp. 685-706
    • Balen, A.1
  • 6
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
    • Dunaif A, Segal KR, Futterweit W, Dobrjansky A (1989) Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes 38:1165-1174 (Pubitemid 19250404)
    • (1989) Diabetes , vol.38 , Issue.9 , pp. 1165-1174
    • Dunaif, A.1    Segal, K.R.2    Futterweit, W.3    Dobrjansky, A.4
  • 7
    • 0029822278 scopus 로고    scopus 로고
    • Insulin and the polycystic ovary syndrome
    • Utiger RD (1996) Insulin and the polycystic ovary syndrome. New Engl J Med 335:657-658
    • (1996) New Engl J Med , vol.335 , pp. 657-658
    • Utiger, R.D.1
  • 9
    • 0003142122 scopus 로고
    • Obesity, lipids, cardiovascular disease and androgen excess
    • Wild RA (1995) Obesity, lipids, cardiovascular disease and androgen excess. Am J Med 98:275-325
    • (1995) Am J Med , vol.98 , pp. 275-325
    • Wild, R.A.1
  • 10
    • 0023890419 scopus 로고
    • Prospective studies of insulin sensitivity in normal women receiving oral contraceptive agents
    • Kasdorf G, Kalkhoff RK (1988) Prospective studies of insulin sensitivity in normal women receiving oral contraceptive agents. J Clin Endocrinol Metab 66:846-852
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 846-852
    • Kasdorf, G.1    Kalkhoff, R.K.2
  • 12
    • 0025176686 scopus 로고
    • Effect of low-dose oral contraceptive on gonadotropins, androgens, and sex hormone binding globulin in nonhirsute women
    • Murphy A, Cropp CS, Smith BS, Burkman RT, Zacur HA (1990) Effect of low dose oral contraceptive on gonadotrophins, androgens and sex hormone binding globulin in nonhirsute women. Fertil Steril 53:35-39 (Pubitemid 20041312)
    • (1990) Fertility and Sterility , vol.53 , Issue.1 , pp. 35-39
    • Murphy, A.A.1    Cropp, C.S.2    Smith, B.S.3    Burkman, R.T.4    Zacur, H.A.5
  • 13
    • 23444459549 scopus 로고    scopus 로고
    • Oral contraceptives and the management of hyperandrogenism - polycystic ovary syndrome in adolescents
    • Hillard PJ (2005) Oral contraceptives and the management of hyperandrogenism - polycystic ovary syndrome in adolescents. Endocrinol Metab Clin North Am 34:707-723
    • (2005) Endocrinol Metab Clin North Am , vol.34 , pp. 707-723
    • Hillard, P.J.1
  • 14
  • 17
    • 0038404516 scopus 로고    scopus 로고
    • The evaluation and management of hirsutism
    • Azziz R (2003) The evaluation and management of hirsutism. Obstet Gynecol 101:995-1007
    • (2003) Obstet Gynecol , vol.101 , pp. 995-1007
    • Azziz, R.1
  • 18
    • 80054123382 scopus 로고    scopus 로고
    • Kaysville, Utah, USA
    • Hintze, J (2001) PASS 11. NCSS, LLC. Kaysville, Utah, USA. http://www.ncss.com
    • (2001) PASS 11
    • Hintze, J.1
  • 19
    • 77955432864 scopus 로고    scopus 로고
    • US Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER)
    • US Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) (2005) Guidance for industry; acne vulgaris: developing drugs for treatment. Rockville, MD
    • (2005) Guidance for Industry; Acne Vulgaris: Developing Drugs for Treatment. Rockville, MD
  • 20
    • 33847027994 scopus 로고    scopus 로고
    • Comparison of two oral contraceptives containing either drospirenone or cyproterone acetate in the treatment of hirsutism
    • Batukan C, Muderris II, Ozcelik B, Ozturk A (2007) Comparison of two oral contraceptives containing either drospirenone or cyproterone acetate in the treatment of hirsutism. Gynecol Endocrinol 23:38-44
    • (2007) Gynecol Endocrinol , vol.23 , pp. 38-44
    • Batukan, C.1    Muderris, I.I.2    Ozcelik, B.3    Ozturk, A.4
  • 23
    • 0033833321 scopus 로고    scopus 로고
    • Drospirenone: Pharmacology and pharmacokinetics of a unique progestogen
    • Krattenmacher R (2000) Drospirenone: pharmacology and pharmacokinetics of a unique progestogen. Contraception 62:29-38
    • (2000) Contraception , vol.62 , pp. 29-38
    • Krattenmacher, R.1
  • 24
    • 0029160057 scopus 로고
    • Medical treatment of androgen-dependent hirsutism
    • Rittmaster RS (1995) Medical treatment of androgen-dependent hirsutism. J Clin Endocrinol Metab 80:2559-2563
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2559-2563
    • Rittmaster, R.S.1
  • 25
  • 26
    • 84867019132 scopus 로고    scopus 로고
    • Comparative study of the therapeutic effects of oral contraceptive pills containing desogestrel, cyproterone acetate, and drospirenone in patients with polycystic ovary syndrome
    • Bhattacharya SM, Jha A (2012) Comparative study of the therapeutic effects of oral contraceptive pills containing desogestrel, cyproterone acetate, and drospirenone in patients with polycystic ovary syndrome. Fertil Steril 98:1053-1059
    • (2012) Fertil Steril , vol.98 , pp. 1053-1059
    • Bhattacharya, S.M.1    Jha, A.2
  • 27
    • 31644443490 scopus 로고    scopus 로고
    • Efficacy of a new oral contraceptive containing drospirenone and ethinyl estradiol in the long-term treatment of hirsutism
    • DOI 10.1016/j.fertnstert.2005.07.1311, PII S0015028205036915
    • Batukan C, Muderris II (2006) Efficacy of a new oral contraceptive containing drospirenone and ethinyl estradiol in the long term treatment of hirsutism. Fertil Steril 85:436-440 (Pubitemid 43170919)
    • (2006) Fertility and Sterility , vol.85 , Issue.2 , pp. 436-440
    • Batukan, C.1    Muderris, I.I.2
  • 28
    • 77955713461 scopus 로고    scopus 로고
    • Effect of oral contraceptive containing ethinyl estradiol combined with drospirenone vs desogestrel on clinical and biochemical parameters in patients with polycystic ovary syndrome
    • Kriplani A, Periyasamy AJ, Agarwal N, Kulshrestha V, Kumar A, Ammini AC (2010) Effect of oral contraceptive containing ethinyl estradiol combined with drospirenone vs desogestrel on clinical and biochemical parameters in patients with polycystic ovary syndrome. Contraception 82:139-146
    • (2010) Contraception , vol.82 , pp. 139-146
    • Kriplani, A.1    Periyasamy, A.J.2    Agarwal, N.3    Kulshrestha, V.4    Kumar, A.5    Ammini, A.C.6
  • 29
    • 0025634135 scopus 로고
    • Long-term treatment with the combination ethinyl estradiol and cyproterone acetate in polycystic ovary syndrome
    • Falsetti L, Galbignani E (1990) Long-term treatment with the combination ethinyl estradiol and cyproterone acetate in polycystic ovary syndrome. Contraception 42:611-619
    • (1990) Contraception , vol.42 , pp. 611-619
    • Falsetti, L.1    Galbignani, E.2
  • 30
    • 0027292405 scopus 로고
    • Results of an open one-year study with Diane-35 in women with polycystic ovarian syndrome
    • Golland IM, Elstein ME (1993) Results of an open one-year study with Diane-35 in women with polycystic ovarian syndrome. Ann N Y Acad Sci 687:263-271 (Pubitemid 23217946)
    • (1993) Annals of the New York Academy of Sciences , vol.687 , pp. 263-271
    • Golland, I.M.1    Elstein, M.E.2
  • 31
    • 0021365612 scopus 로고
    • Effect of an oral contraceptive on adrenal and ovarian androgenic steroids
    • Wiebe RH, Morris CV (1984) Effect of an oral contraceptive on adrenal and ovarian androgenic steroids. Obstet Gynecol 63:12-14 (Pubitemid 14221911)
    • (1984) Obstetrics and Gynecology , vol.63 , Issue.1 , pp. 12-14
    • Wiebe, R.H.1    Morris, C.V.2
  • 32
    • 31644449390 scopus 로고    scopus 로고
    • Effects of two forms of combined oral contraceptives on carbohydrate metabolism in adolescents with polycystic ovary syndrome
    • DOI 10.1016/j.fertnstert.2005.07.1306, PII S0015028205036861
    • .Mastorakos G, Koliopoulos C, Deligeoroglou E, Diamant-Kandarakis E, Creatsas G (2006) Effects of two forms of combined oral contraceptives on carbohydrate metabolism in adolescents with polycystic ovary syndrome. Fertil Steril 85:420-427 (Pubitemid 43170917)
    • (2006) Fertility and Sterility , vol.85 , Issue.2 , pp. 420-427
    • Mastorakos, G.1    Koliopoulos, C.2    Deligeoroglou, E.3    Diamanti-Kandarakis, E.4    Creatsas, G.5
  • 33
    • 0041883275 scopus 로고    scopus 로고
    • Glucose metabolism and insulin resistance in women with polycystic ovary syndrome during therapy with oral contraceptives containing cyproterone acetate or desogestrel
    • DOI 10.1210/jc.2003-030328
    • .Cagnacci A, Paoletti AM, Renzi A, Orru M, Pilloni M, Melis GB et al (2003) Glucose metabolism and insulin resistance in women with polycystic ovary syndrome during therapy with oral contraceptives containing cyproterone acetate or desogestrel. J Clin Endocrinol Metab 88:3621-3625 (Pubitemid 37034504)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.8 , pp. 3621-3625
    • Cagnacci, A.1    Paoletti, A.M.2    Renzi, A.3    Orru, M.4    Pilloni, M.5    Melis, G.B.6    Volpe, A.7
  • 34
    • 78650715566 scopus 로고    scopus 로고
    • The association between the combined oral contraceptive pill and insulin resistance, dysglycemia and dyslipidemia in women with polycystic ovary syndrome: A systematic review and meta-analysis of observational studies
    • .Halperin IJ, Kumar SS, Stroup DF, Laredo SE (2011) The association between the combined oral contraceptive pill and insulin resistance, dysglycemia and dyslipidemia in women with polycystic ovary syndrome: a systematic review and meta-analysis of observational studies. Hum Reprod 26:191-201
    • (2011) Hum Reprod , vol.26 , pp. 191-201
    • Halperin, I.J.1    Kumar, S.S.2    Stroup, D.F.3    Laredo, S.E.4
  • 35
    • 0942265414 scopus 로고    scopus 로고
    • Detecting Insulin Resistance in Polycystic Ovary Syndrome: Purposes and Pitfalls
    • DOI 10.1097/01.OGX.0000109523.25076.E2
    • .Legro RS, Castracane VD, Kauffman RP (2004) Detecting insulin resistance in polycystic ovary syndrome: purposes and pitfalls. Obstet Gynecol Surv 59:141-154 (Pubitemid 38140845)
    • (2004) Obstetrical and Gynecological Survey , vol.59 , Issue.2 , pp. 141-154
    • Legro, R.S.1    Castracane, V.D.2    Kauffman, R.P.3
  • 36
    • 0036253418 scopus 로고    scopus 로고
    • Androgen and lipid profiles in adolescents with polycystic ovary syndrome who were treated with two forms of combined oral contraceptives
    • DOI 10.1016/S0015-0282(02)02993-X, PII S001502820202993X
    • .Mastorakos G, Koliopoulos C, Creatsas G (2002) Androgen and lipid profiles in adolescents with polycystic ovary syndrome who were treated with two forms of combined oral contraceptives. Fertil Steril 77:919-927 (Pubitemid 34497157)
    • (2002) Fertility and Sterility , vol.77 , Issue.5 , pp. 919-927
    • Mastorakos, G.1    Koliopoulos, C.2    Creatsas, G.3
  • 37
    • 19444379341 scopus 로고    scopus 로고
    • Effects of two combined oral contraceptives containing ethinyl estradiol 20 microg combined with either drospirenone or desogestrel on lipids, hemostatic parameters and carbohydrate metabolism
    • DOI 10.1016/j.contraception.2004.12.005, PII S0010782405000193
    • Klipping C, Marr J (2005) Effects of two combined oral contraceptives containing ethinyl estradiol 20 microg combined with either drospirenone or desogestrel on lipids, hemostatic parameters and carbohydrate metabolism. Contraception 71:409-416 (Pubitemid 40725775)
    • (2005) Contraception , vol.71 , Issue.6 , pp. 409-416
    • Klipping, C.1    Marr, J.2
  • 38
    • 0029011362 scopus 로고
    • Effects of new oral contraceptive containing an antimineralocorticoid progestogen drospirenone on the rennin-aldosterone system, body weight, blood pressure, glucose tolerance and lipid metabolism
    • Oelkers W, Foidart JM, Dombrovicz N, Welter A, Heithecker R (1995) Effects of new oral contraceptive containing an antimineralocorticoid progestogen drospirenone on the rennin-aldosterone system, body weight, blood pressure, glucose tolerance and lipid metabolism. J Clin Endocrinol Metab 80:1816-1821
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1816-1821
    • Oelkers, W.1    Foidart, J.M.2    Dombrovicz, N.3    Welter, A.4    Heithecker, R.5
  • 39
    • 41649115784 scopus 로고    scopus 로고
    • Effects of third-generation oral contraceptives on high-sensitivity C-reactive protein and homocysteine in young women
    • DOI 10.1097/AOG.0b013e31816a2476, PII 0000625020080400000009
    • .Cauci S, Di Santolo M, Culhane JF, Stel G, Gonano F, Guaschino S (2008) Effects of third-generation oral contraceptives on highsensitivity C-reactive protein and homocysteine in young women. Obstet Gynecol 111:857-864 (Pubitemid 351482617)
    • (2008) Obstetrics and Gynecology , vol.111 , Issue.4 , pp. 857-864
    • Cauci, S.1    Di, S.M.2    Culhane, J.F.3    Stel, G.4    Gonano, F.5    Guaschino, S.6
  • 40
    • 80051525379 scopus 로고    scopus 로고
    • Inflammatory-metabolic parameters in obese and nonobese normoandrogenemic polycystic ovary syndrome during metformin and oral contraceptive treatment
    • .Kilic S, Yilmaz N, Zulfikaroglu E, Erdogan G, Aydin M, Batioglu S (2011) Inflammatory-metabolic parameters in obese and nonobese normoandrogenemic polycystic ovary syndrome during metformin and oral contraceptive treatment. Gynecol Endocrinol 27:622-629
    • (2011) Gynecol Endocrinol , vol.27 , pp. 622-629
    • Kilic, S.1    Yilmaz, N.2    Zulfikaroglu, E.3    Erdogan, G.4    Aydin, M.5    Batioglu, S.6
  • 41
    • 83455188089 scopus 로고    scopus 로고
    • Effect of oral contraceptive therapy on homocysteine and C-reactive protein levels in women: An observational study
    • .Norouzi V, Seifi M, Fallah S, Korani M, Samadikuchaksaraei A (2011) Effect of oral contraceptive therapy on homocysteine and C-reactive protein levels in women: an observational study. Anadolu Kardiyol Derg 11:698-702
    • (2011) Anadolu Kardiyol Derg , vol.11 , pp. 698-702
    • Norouzi, V.1    Seifi, M.2    Fallah, S.3    Korani, M.4    Samadikuchaksaraei, A.5
  • 42
    • 33644867982 scopus 로고    scopus 로고
    • Effects of two different oral contraceptives on homocysteine metabolism in women with polycystic ovary syndrome
    • DOI 10.1016/j.contraception.2005.09.011, PII S0010782405003690
    • .Cagnacci A, Tirelli A, Renzi A, Paoletti AM, Volpe A (2006) Effects of two different oral contraceptives on homocysteine metabolism in women with polycystic ovary syndrome. Contraception 73:348-351 (Pubitemid 43375092)
    • (2006) Contraception , vol.73 , Issue.4 , pp. 348-351
    • Cagnacci, A.1    Tirelli, A.2    Renzi, A.3    Paoletti, A.M.4    Volpe, A.5
  • 43
    • 84155163090 scopus 로고    scopus 로고
    • Consensus on women's health aspects of polycystic ovary syndrome (PCOS): The Amsterdam ESHRE/ASRMSponsored 3rd PCOS consensus workshop group
    • Fauser BCJM, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R et al (2012) Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRMSponsored 3rd PCOS consensus workshop group. Fertil Steril 97:28-38
    • (2012) Fertil Steril , vol.97 , pp. 28-38
    • Fauser, B.C.J.M.1    Tarlatzis, B.C.2    Rebar, R.W.3    Legro, R.S.4    Balen, A.H.5    Lobo, R.6
  • 44
    • 84873396245 scopus 로고    scopus 로고
    • Risk of venous thromboembolism in women with polycystic ovary syndrome: A population-based matched cohort analysis
    • Bird ST, Hartzema AG, Brophy JM, Etminan M, Delaney JAC (2013) Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. CMAJ 185:E115-E120
    • (2013) CMAJ , vol.185
    • Bird, S.T.1    Hartzema, A.G.2    Brophy, J.M.3    Etminan, M.4    Delaney, J.A.C.5


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