메뉴 건너뛰기




Volumn 89, Issue 6, 2004, Pages 2817-2823

Drospirenone for the treatment of hirsute women with polycystic ovary syndrome: A clinical, endocrinological, metabolic pilot study

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; CHOLESTEROL; DROSPIRENONE; ESTROGEN DERIVATIVE; ETHINYLESTRADIOL; FAT; GESTAGEN; GLUCOSE; HIGH DENSITY LIPOPROTEIN; HORMONE; HYDROXYPROGESTERONE; INSULIN; LIPID; LOW DENSITY LIPOPROTEIN; LUTEINIZING HORMONE; PRASTERONE; PROGESTERONE DERIVATIVE; TESTOSTERONE; TRIACYLGLYCEROL;

EID: 2942631366     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031158     Document Type: Conference Paper
Times cited : (137)

References (43)
  • 1
    • 0029095150 scopus 로고
    • Polycystic ovary syndrome
    • Franks S 1995 Polycystic ovary syndrome. N Engl J Med 333:853-861
    • (1995) N Engl J Med , vol.333 , pp. 853-861
    • Franks, S.1
  • 2
    • 0027292405 scopus 로고
    • Results of an open one-year study with Diane 35 in women with polycystic ovary syndrome
    • Golland IM, Elstein ME 1993 Results of an open one-year study with Diane 35 in women with polycystic ovary syndrome. Ann NY Acad Sci 687:263-271
    • (1993) Ann NY Acad Sci , vol.687 , pp. 263-271
    • Golland, I.M.1    Elstein, M.E.2
  • 3
    • 0025634135 scopus 로고
    • Long term treatment with the combination ethinyl-estradiol and cyproterone acetate in polycystic ovary syndrome
    • Falsetti L, Galbignani E 1990 Long term treatment with the combination ethinyl-estradiol and cyproterone acetate in polycystic ovary syndrome. Contraception 42:611-619
    • (1990) Contraception , vol.42 , pp. 611-619
    • Falsetti, L.1    Galbignani, E.2
  • 4
    • 0036858867 scopus 로고    scopus 로고
    • Safety and efficacy of a new oral contraceptive containing drospirenone
    • Shulman LP 2002 Safety and efficacy of a new oral contraceptive containing drospirenone. J Reprod Med 47(Suppl 11):981-984
    • (2002) J Reprod Med , vol.47 , Issue.11 SUPPL. , pp. 981-984
    • Shulman, L.P.1
  • 5
    • 0036856913 scopus 로고    scopus 로고
    • Evolution of progestins. Focus on the novel progestin drospirenone
    • Thorneycroft IH 2002 Evolution of progestins. Focus on the novel progestin drospirenone. J Reprod Med 47(Suppl 11):975-980
    • (2002) J Reprod Med , vol.47 , Issue.11 SUPPL. , pp. 975-980
    • Thorneycroft, I.H.1
  • 7
    • 84920244726 scopus 로고
    • Multifollicular ovaries: Clinical and endocrine features and response to gonadotropin releasing hormone
    • Adams J, Polson DW, Abdulwahid N 1985 Multifollicular ovaries: clinical and endocrine features and response to gonadotropin releasing hormone. Lancet 2:1375-1378
    • (1985) Lancet , vol.2 , pp. 1375-1378
    • Adams, J.1    Polson, D.W.2    Abdulwahid, N.3
  • 8
    • 0034901923 scopus 로고    scopus 로고
    • A new ultrasound criterion for the diagnosis of polycystic ovary syndrome: The ovarian stroma/total area ratio
    • Fulghesu AM, Ciampelli M, Belosi C, Apa R, Pavone V, Lanzone A 2001 A new ultrasound criterion for the diagnosis of polycystic ovary syndrome: the ovarian stroma/total area ratio. Fertil Steril 76:326-331
    • (2001) Fertil Steril , vol.76 , pp. 326-331
    • Fulghesu, A.M.1    Ciampelli, M.2    Belosi, C.3    Apa, R.4    Pavone, V.5    Lanzone, A.6
  • 9
  • 12
    • 0034970035 scopus 로고    scopus 로고
    • Increased visceral adipose tissue is associated with increased circulating insulin and decreased sex hormone binding globulin levels in massively obese adolescent girls
    • De Simone M, Verrotti A, Iughetti L, Palombo M, Farello G, Di Cesare E, Bernabei R, Rosato T, Lozzi S, Ciescione S 2001 Increased visceral adipose tissue is associated with increased circulating insulin and decreased sex hormone binding globulin levels in massively obese adolescent girls. J Endocrinol Invest 24:438-444
    • (2001) J Endocrinol Invest , vol.24 , pp. 438-444
    • De Simone, M.1    Verrotti, A.2    Iughetti, L.3    Palombo, M.4    Farello, G.5    Di Cesare, E.6    Bernabei, R.7    Rosato, T.8    Lozzi, S.9    Ciescione, S.10
  • 13
    • 12644305063 scopus 로고
    • Clinical assessment of body hair growth in women
    • Ferriman D, Gallwey JD 1961 Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 21:1440-1447
    • (1961) J Clin Endocrinol Metab , vol.21 , pp. 1440-1447
    • Ferriman, D.1    Gallwey, J.D.2
  • 14
    • 0018520840 scopus 로고
    • Glucose clamp Technique: A method for quantifying insulin secretion and resistance
    • De Fronzo JP, Tobin JD, Andrei R 1979 Glucose clamp Technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223
    • (1979) Am J Physiol , vol.237
    • De Fronzo, J.P.1    Tobin, J.D.2    Andrei, R.3
  • 15
  • 16
    • 0028213422 scopus 로고
    • New progestogens in oral contraception
    • Fotherby K, Caldwell AD 1994 New progestogens in oral contraception. Contraception 49:1-32
    • (1994) Contraception , vol.49 , pp. 1-32
    • Fotherby, K.1    Caldwell, A.D.2
  • 17
    • 0028952384 scopus 로고
    • The androgenicity of progestins
    • Darney PD 1995 The androgenicity of progestins. Am J Med 98(Suppl 1A): 104s-110s
    • (1995) Am J Med , vol.98 , Issue.SUPPL. 1A
    • Darney, P.D.1
  • 19
    • 0033833321 scopus 로고    scopus 로고
    • Drospirenone: Pharmacology and pharmacokinetics of a unique progestogen
    • Krattenmacher R 2000 Drospirenone: pharmacology and pharmacokinetics of a unique progestogen. Contraception 62:29-38
    • (2000) Contraception , vol.62 , pp. 29-38
    • Krattenmacher, R.1
  • 20
    • 0030273673 scopus 로고    scopus 로고
    • The novel progestin drospirenone and its natural counterpart progesterone: Biochemical profile and antiandrogenic potential
    • Fuhrmann U, Krattenmacher R, Slater EP, Fritzemeier KH 1996 The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential. Contraception 54:243-251
    • (1996) Contraception , vol.54 , pp. 243-251
    • Fuhrmann, U.1    Krattenmacher, R.2    Slater, E.P.3    Fritzemeier, K.H.4
  • 21
    • 0016193526 scopus 로고
    • Dynamic of suppression and recovery of plasma FSH, LH, androstenedione and testosterone in polycystic ovarian disease using an oral contraceptive
    • Givens JR, Andersen RN, Wiser WL, Fish SA 1974 Dynamic of suppression and recovery of plasma FSH, LH, androstenedione and testosterone in polycystic ovarian disease using an oral contraceptive. J Clin Endocrinol Metab 38:727-735
    • (1974) J Clin Endocrinol Metab , vol.38 , pp. 727-735
    • Givens, J.R.1    Andersen, R.N.2    Wiser, W.L.3    Fish, S.A.4
  • 22
    • 0028910917 scopus 로고
    • Drospirenone: A novel progestogen with antimineralocorticoid and antiandrogenic activity: Pharmacological characterization in animal models
    • Muhn P, Krattenmacher R, Beier S, Elger W, Schillinger E 1995 Drospirenone: a novel progestogen with antimineralocorticoid and antiandrogenic activity: pharmacological characterization in animal models. Contraception 51:99-110
    • (1995) Contraception , vol.51 , pp. 99-110
    • Muhn, P.1    Krattenmacher, R.2    Beier, S.3    Elger, W.4    Schillinger, E.5
  • 24
    • 0036869152 scopus 로고    scopus 로고
    • Regulation of gonadotropin secretion: Implications for polycystic ovary syndrome
    • McCartney, Eagleson CA, Marshall JC 2002 Regulation of gonadotropin secretion: implications for polycystic ovary syndrome. Semin Reprod Med 20: 317-326
    • (2002) Semin Reprod Med , vol.20 , pp. 317-326
    • McCartney1    Eagleson, C.A.2    Marshall, J.C.3
  • 25
    • 0022081697 scopus 로고
    • Insulin-like growth factor as intraovarian regulators of granulosa cell growth and function
    • Adashi EY, Resnick CE, D'Ercole J, Svoboda ME, Van Wyk JJ 1985 Insulin-like growth factor as intraovarian regulators of granulosa cell growth and function. Endocr Rev 6:400-420
    • (1985) Endocr Rev , vol.6 , pp. 400-420
    • Adashi, E.Y.1    Resnick, C.E.2    D'Ercole, J.3    Svoboda, M.E.4    Van Wyk, J.J.5
  • 26
    • 0035187245 scopus 로고    scopus 로고
    • Efficacy of the combination ethinyl oestradiol and cyproterone acetate on endocrine, clinical and ultrasonographic profile in polycystic ovarian syndrome
    • Falsetti L, Gambera A, Tisi G 2001 Efficacy of the combination ethinyl oestradiol and cyproterone acetate on endocrine, clinical and ultrasonographic profile in polycystic ovarian syndrome. Hum Reprod 16:36-42
    • (2001) Hum Reprod , vol.16 , pp. 36-42
    • Falsetti, L.1    Gambera, A.2    Tisi, G.3
  • 27
    • 0019944608 scopus 로고
    • Effect of cyproterone acetate-ethinyl oestradiol treatment on adrenal function in hirsute women
    • Oxf
    • Chapman MG, Jeffcoate SL, Dewhurst CJ 1982 Effect of cyproterone acetate-ethinyl oestradiol treatment on adrenal function in hirsute women. Clin Endocrinol (Oxf) 17:577-582
    • (1982) Clin Endocrinol , vol.17 , pp. 577-582
    • Chapman, M.G.1    Jeffcoate, S.L.2    Dewhurst, C.J.3
  • 28
    • 0036547728 scopus 로고    scopus 로고
    • The effect of 2 combined oral contraceptives containing either drospirenone or cyproterone acetate on acne and seborrhea
    • van Vloten WA, van Haselen CW, van Zuuren EJ, Gerlinger C, Heithecker R 2002 The effect of 2 combined oral contraceptives containing either drospirenone or cyproterone acetate on acne and seborrhea. Cutis 69(Suppl 4):2-15
    • (2002) Cutis , vol.69 , Issue.4 SUPPL. , pp. 2-15
    • Van Vloten, W.A.1    Van Haselen, C.W.2    Van Zuuren, E.J.3    Gerlinger, C.4    Heithecker, R.5
  • 29
    • 0028213422 scopus 로고
    • New progestogens in oral contraception
    • Fotherby K, Caldwell AD 1994 New progestogens in oral contraception. Contraception 49:1-32
    • (1994) Contraception , vol.49 , pp. 1-32
    • Fotherby, K.1    Caldwell, A.D.2
  • 30
    • 0034113351 scopus 로고    scopus 로고
    • Increased activity of the hypothalamus-pituitary-adrenal system after treatment with the mineralocorticoid receptor antagonist spironolactone
    • Heuser I, Deuschle M, Weber B, Stalla GK, Holsboer F 2000 Increased activity of the hypothalamus-pituitary-adrenal system after treatment with the mineralocorticoid receptor antagonist spironolactone. Psychoneuroendocrinology 25:513-518
    • (2000) Psychoneuroendocrinology , vol.25 , pp. 513-518
    • Heuser, I.1    Deuschle, M.2    Weber, B.3    Stalla, G.K.4    Holsboer, F.5
  • 31
    • 0031769481 scopus 로고    scopus 로고
    • The role of mineralocorticoid receptors in hypothalamic-pituitary-adrenal axis regulation in humans
    • Young EA, Lopez JF, Murphy-Weinberg V, Watson SJ, Akil H 1998 The role of mineralocorticoid receptors in hypothalamic-pituitary-adrenal axis regulation in humans. J Clin Endocrinol Metab 83:3339-3345
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3339-3345
    • Young, E.A.1    Lopez, J.F.2    Murphy-Weinberg, V.3    Watson, S.J.4    Akil, H.5
  • 32
    • 0029917954 scopus 로고    scopus 로고
    • Effects of estrgens and progestgens on the renin-aldosterone system and blood pressure
    • Oelkers WK 1996 Effects of estrgens and progestgens on the renin-aldosterone system and blood pressure. Steroids 61:166-171
    • (1996) Steroids , vol.61 , pp. 166-171
    • Oelkers, W.K.1
  • 33
    • 0025993839 scopus 로고
    • Dihydrospirenone, a new progestogen with antimineralocorticoid activity: Effects on ovulation, electrolyte excretion and the renin-aldosterone system in normal women
    • Oelkers W, Berger V, Bolik A, Bahr V, Hazard B, Beier S, Elger W, Heithecker A 1991 Dihydrospirenone, a new progestogen with antimineralocorticoid activity: effects on ovulation, electrolyte excretion and the renin-aldosterone system in normal women. J Clin Endocrinol Metab 73:837-842
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 837-842
    • Oelkers, W.1    Berger, V.2    Bolik, A.3    Bahr, V.4    Hazard, B.5    Beier, S.6    Elger, W.7    Heithecker, A.8
  • 34
    • 0029011362 scopus 로고
    • Effects of new oral contraceptive containing an antimineralocorticoid progestogen, drospirenone, on the renin-aldosterone system, body weight, blood pressure, glucose tolerance, and lipid metabolism
    • Oelkers W, Foidart JM, Dombrovicz N, Welter A, Heithecker R 1995 Effects of new oral contraceptive containing an antimineralocorticoid progestogen, drospirenone, on the renin-aldosterone system, body weight, blood pressure, glucose tolerance, and lipid metabolism. J Clin Endocrinol Metab 80:1816-1821
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1816-1821
    • Oelkers, W.1    Foidart, J.M.2    Dombrovicz, N.3    Welter, A.4    Heithecker, R.5
  • 35
    • 0034058861 scopus 로고    scopus 로고
    • An open-label, multicenter study to evaluate Yasmn, a low-dose combination oral contraceptive containing drospirenone, a new progestogen
    • Parsey KS, Pong A 2000 An open-label, multicenter study to evaluate Yasmn, a low-dose combination oral contraceptive containing drospirenone, a new progestogen. Contraception 61:105-111
    • (2000) Contraception , vol.61 , pp. 105-111
    • Parsey, K.S.1    Pong, A.2
  • 36
    • 2942661218 scopus 로고
    • Oral contraceptives and changes in glucose metabolism: Clinical relevance?
    • Skouby SO 1991 Oral contraceptives and changes in glucose metabolism: clinical relevance? Adv Contraception 7(Suppl 3):207-212
    • (1991) Adv Contraception , vol.7 , Issue.3 SUPPL. , pp. 207-212
    • Skouby, S.O.1
  • 37
    • 0020060562 scopus 로고
    • Carbohydrate metabolism during treatment with estrgen, progestogen and low-dose oral contraceptives
    • Spellacy WN 1982 Carbohydrate metabolism during treatment with estrgen, progestogen and low-dose oral contraceptives. Am J Obstet Gynecol 142:732-734
    • (1982) Am J Obstet Gynecol , vol.142 , pp. 732-734
    • Spellacy, W.N.1
  • 39
    • 19244367470 scopus 로고    scopus 로고
    • Acute myocardial infarction and combined oral contraceptives: Results of international multicenter case-control study: WHO Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception
    • WHO 1997 Acute myocardial infarction and combined oral contraceptives: results of international multicenter case-control study: WHO Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception. Lancet 349:1202-1209
    • (1997) Lancet , vol.349 , pp. 1202-1209
  • 40
    • 0035984973 scopus 로고    scopus 로고
    • Long-term health consequences of PCOS
    • Wild RA 2002 Long-term health consequences of PCOS. Hum Reprod Update 8:231-241
    • (2002) Hum Reprod Update , vol.8 , pp. 231-241
    • Wild, R.A.1
  • 41
    • 2942661219 scopus 로고
    • Clinical relevance of plasma lipid changes during use of new low-dose oral contraceptives
    • Gaspard UJ 1991 Clinical relevance of plasma lipid changes during use of new low-dose oral contraceptives. Adv Contraception 7(Suppl 1):180-194
    • (1991) Adv Contraception , vol.7 , Issue.1 SUPPL. , pp. 180-194
    • Gaspard, U.J.1
  • 42
    • 0032415718 scopus 로고    scopus 로고
    • The new pathophysiology of coronary artery disease
    • Castelli WP 1998 The new pathophysiology of coronary artery disease. Am J Cardiol 82:60t-65t
    • (1998) Am J Cardiol , vol.82
    • Castelli, W.P.1
  • 43
    • 0035059042 scopus 로고    scopus 로고
    • Cardiovascular risk factors and prevention in women: Similarities and differences
    • Sclavo M 2001 Cardiovascular risk factors and prevention in women: similarities and differences. Ital Heart J 2(Suppl 2):125-141
    • (2001) Ital Heart J , vol.2 , Issue.2 SUPPL. , pp. 125-141
    • Sclavo, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.