-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin 2011;61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA: Hallmarks of cancer: the next generation. Cell 2011;144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
84859721377
-
JAK2 inhibition for the treatment of hematologic and solid malignancies
-
Harry BL, Eckhardt SG, Jimeno A: JAK2 inhibition for the treatment of hematologic and solid malignancies. Expert Opin Investig Drugs 2012;21:637-655.
-
(2012)
Expert Opin Investig Drugs
, vol.21
, pp. 637-655
-
-
Harry, B.L.1
Eckhardt, S.G.2
Jimeno, A.3
-
4
-
-
77649207043
-
Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells
-
Behera R, Kumar V, Lohite K, Karnik S, Kundu GC: Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells. Carcinogenesis 2010;31:192-200.
-
(2010)
Carcinogenesis
, vol.31
, pp. 192-200
-
-
Behera, R.1
Kumar, V.2
Lohite, K.3
Karnik, S.4
Kundu, G.C.5
-
5
-
-
0030953788
-
The kinase domain of Jak2 mediates induction of Bcl-2 and delays cell death in hematopoietic cells
-
Sakai I, Kraft AS: The kinase domain of Jak2 mediates induction of Bcl-2 and delays cell death in hematopoietic cells. J Biol Chem 1997;272:12350-12358.
-
(1997)
J Biol Chem
, vol.272
, pp. 12350-12358
-
-
Sakai, I.1
Kraft, A.S.2
-
7
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
8
-
-
59649125888
-
Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs
-
Gu S, Jin L, Zhang F, Sarnow P, Kay MA: Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs. Nat Struct Mol Biol 2009;16:144-150.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 144-150
-
-
Gu, S.1
Jin, L.2
Zhang, F.3
Sarnow, P.4
Kay, M.A.5
-
9
-
-
84857079737
-
The microcosmos of cancer
-
Lujambio A, Lowe SW: The microcosmos of cancer. Nature 2012;482:347-355.
-
(2012)
Nature
, vol.482
, pp. 347-355
-
-
Lujambio, A.1
Lowe, S.W.2
-
10
-
-
84879484616
-
MicroRNA-124 suppresses breast cancer cell growth and motility by targeting CD151
-
Han ZB, Yang Z, Chi Y, Zhang L, Wang Y, Ji Y, Wang J, Zhao H, Han ZC: MicroRNA-124 suppresses breast cancer cell growth and motility by targeting CD151. Cell Physiol Biochem 2013;31:823-832.
-
(2013)
Cell Physiol Biochem
, vol.31
, pp. 823-832
-
-
Han, Z.B.1
Yang, Z.2
Chi, Y.3
Zhang, L.4
Wang, Y.5
Ji, Y.6
Wang, J.7
Zhao, H.8
Han, Z.C.9
-
11
-
-
84864090039
-
Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells
-
Li LQ, Li XL, Wang L, Du WJ, Guo R, Liang HH, Liu X, Liang DS, Lu YJ, Shan HL, Jiang HC: Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells. Cell Physiol Biochem 2012;30:631-641.
-
(2012)
Cell Physiol Biochem
, vol.30
, pp. 631-641
-
-
Li, L.Q.1
Li, X.L.2
Wang, L.3
Du, W.J.4
Guo, R.5
Liang, H.H.6
Liu, X.7
Liang, D.S.8
Lu, Y.J.9
Shan, H.L.10
Jiang, H.C.11
-
12
-
-
84876741644
-
MiR-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through NF-kappaB pathways
-
Zhang L, Yang L, Liu X, Chen W, Chang L, Chen L, Loera S, Chu P, Huang WC, Liu YR, Yen Y: MiR-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through NF-kappaB pathways. Hepatology 2013;57:1919-1930.
-
(2013)
Hepatology
, vol.57
, pp. 1919-1930
-
-
Zhang, L.1
Yang, L.2
Liu, X.3
Chen, W.4
Chang, L.5
Chen, L.6
Loera, S.7
Chu, P.8
Huang, W.C.9
Liu, Y.R.10
Yen, Y.11
-
13
-
-
34548687035
-
Mir-29 regulates Mcl-1 protein expression and apoptosis
-
Mott JL, Kobayashi S, Bronk SF, Gores GJ: mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 2007;26:6133-6140.
-
(2007)
Oncogene
, vol.26
, pp. 6133-6140
-
-
Mott, J.L.1
Kobayashi, S.2
Bronk, S.F.3
Gores, G.J.4
-
14
-
-
62549148270
-
P53 represses c-Myc through induction of the tumor suppressor miR-145
-
Sachdeva M, Zhu S, Wu F, Wu H, Walia V, Kumar S, Elble R, Watabe K, Mo YY: p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009;106:3207-3212.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3207-3212
-
-
Sachdeva, M.1
Zhu, S.2
Wu, F.3
Wu, H.4
Walia, V.5
Kumar, S.6
Elble, R.7
Watabe, K.8
Mo, Y.Y.9
-
15
-
-
84872962383
-
Loss of miR-101 expression promotes Wnt/beta-catenin signalling pathway activation and malignancy in colon cancer cells
-
Strillacci A, Valerii MC, Sansone P, Caggiano C, Sgromo A, Vittori L, Fiorentino M, Poggioli G, Rizzello F, Campieri M, Spisni E: Loss of miR-101 expression promotes Wnt/beta-catenin signalling pathway activation and malignancy in colon cancer cells. J Pathol 2013;229:379-389.
-
(2013)
J Pathol
, vol.229
, pp. 379-389
-
-
Strillacci, A.1
Valerii, M.C.2
Sansone, P.3
Caggiano, C.4
Sgromo, A.5
Vittori, L.6
Fiorentino, M.7
Poggioli, G.8
Rizzello, F.9
Campieri, M.10
Spisni, E.11
-
16
-
-
84869029319
-
Identification of a two-layer regulatory network of proliferation-related microRNAs in hepatoma cells
-
Huang Y, Chen HC, Chiang CW, Yeh CT, Chen SJ, Chou CK: Identification of a two-layer regulatory network of proliferation-related microRNAs in hepatoma cells. Nucleic Acids Res 2012;40:10478-10493.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 10478-10493
-
-
Huang, Y.1
Chen, H.C.2
Chiang, C.W.3
Yeh, C.T.4
Chen, S.J.5
Chou, C.K.6
-
17
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, Laxman B, Cao X, Jing X, Ramnarayanan K, Brenner JC, Yu J, Kim JH, Han B, Tan P, Kumar-Sinha C, Lonigro RJ, Palanisamy N, Maher CA, Chinnaiyan AM: Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 2008;322:1695-1699.
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
Cao, Q.2
Mani, R.S.3
Shankar, S.4
Wang, X.5
Ateeq, B.6
Laxman, B.7
Cao, X.8
Jing, X.9
Ramnarayanan, K.10
Brenner, J.C.11
Yu, J.12
Kim, J.H.13
Han, B.14
Tan, P.15
Kumar-Sinha, C.16
Lonigro, R.J.17
Palanisamy, N.18
Maher, C.A.19
Chinnaiyan, A.M.20
more..
-
18
-
-
67651111989
-
Down-regulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines
-
Shan H, Zhang Y, Lu Y, Pan Z, Cai B, Wang N, Li X, Feng T, Hong Y, Yang B: Down-regulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines. Cardiovasc Res 2009;83:465-472.
-
(2009)
Cardiovasc Res
, vol.83
, pp. 465-472
-
-
Shan, H.1
Zhang, Y.2
Lu, Y.3
Pan, Z.4
Cai, B.5
Wang, N.6
Li, X.7
Feng, T.8
Hong, Y.9
Yang, B.10
-
19
-
-
78650701405
-
MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation
-
Lu Y, Zhang Y, Wang N, Pan Z, Gao X, Zhang F, Shan H, Luo X, Bai Y, Sun L, Song W, Xu C, Wang Z, Yang B: MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation. Circulation 2010;122:2378-2387.
-
(2010)
Circulation
, vol.122
, pp. 2378-2387
-
-
Lu, Y.1
Zhang, Y.2
Wang, N.3
Pan, Z.4
Gao, X.5
Zhang, F.6
Shan, H.7
Luo, X.8
Bai, Y.9
Sun, L.10
Song, W.11
Xu, C.12
Wang, Z.13
Yang, B.14
-
20
-
-
84865440355
-
MiRNA expression analysis of cancer-associated fibroblasts and normal fibroblasts in breast cancer
-
Zhao L, Sun Y, Hou Y, Peng Q, Wang L, Luo H, Tang X, Zeng Z, Liu M: MiRNA expression analysis of cancer-associated fibroblasts and normal fibroblasts in breast cancer. Int J Biochem Cell Biol 2012;44:2051-2059.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 2051-2059
-
-
Zhao, L.1
Sun, Y.2
Hou, Y.3
Peng, Q.4
Wang, L.5
Luo, H.6
Tang, X.7
Zeng, Z.8
Liu, M.9
-
22
-
-
84855405573
-
Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression
-
Bao B, Ali S, Banerjee S, Wang Z, Logna F, Azmi AS, Kong D, Ahmad A, Li Y, Padhye S, Sarkar FH: Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression. Cancer Res 2012;72:335-345.
-
(2012)
Cancer Res
, vol.72
, pp. 335-345
-
-
Bao, B.1
Ali, S.2
Banerjee, S.3
Wang, Z.4
Logna, F.5
Azmi, A.S.6
Kong, D.7
Ahmad, A.8
Li, Y.9
Padhye, S.10
Sarkar, F.H.11
-
23
-
-
84864749110
-
Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer
-
Carvalho J, van Grieken NC, Pereira PM, Sousa S, Tijssen M, Buffart TE, Diosdado B, Grabsch H, Santos MA, Meijer G, Seruca R, Carvalho B, Oliveira C: Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer. J Pathol 2012;228:31-44.
-
(2012)
J Pathol
, vol.228
, pp. 31-44
-
-
Carvalho, J.1
Van Grieken, N.C.2
Pereira, P.M.3
Sousa, S.4
Tijssen, M.5
Buffart, T.E.6
Diosdado, B.7
Grabsch, H.8
Santos, M.A.9
Meijer, G.10
Seruca, R.11
Carvalho, B.12
Oliveira, C.13
-
24
-
-
59149098054
-
MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity
-
Su H, Yang JR, Xu T, Huang J, Xu L, Yuan Y, Zhuang SM: MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res 2009;69:1135-1142.
-
(2009)
Cancer Res
, vol.69
, pp. 1135-1142
-
-
Su, H.1
Yang, J.R.2
Xu, T.3
Huang, J.4
Xu, L.5
Yuan, Y.6
Zhuang, S.M.7
-
25
-
-
84868201639
-
Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth
-
He XP, Shao Y, Li XL, Xu W, Chen GS, Sun HH, Xu HC, Xu X, Tang D, Zheng XF, Xue YP, Huang GC, Sun WH: Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth. FEBS J 2012;279:4201-4212.
-
(2012)
FEBS J
, vol.279
, pp. 4201-4212
-
-
He, X.P.1
Shao, Y.2
Li, X.L.3
Xu, W.4
Chen, G.S.5
Sun, H.H.6
Xu, H.C.7
Xu, X.8
Tang, D.9
Zheng, X.F.10
Xue, Y.P.11
Huang, G.C.12
Sun, W.H.13
-
26
-
-
84862560519
-
Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer
-
Ren G, Baritaki S, Marathe H, Feng J, Park S, Beach S, Bazeley PS, Beshir AB, Fenteany G, Mehra R, Daignault S, Al-Mulla F, Keller E, Bonavida B, de la Serna I, Yeung KC: Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer. Cancer Res 2012;72:3091-3104.
-
(2012)
Cancer Res
, vol.72
, pp. 3091-3104
-
-
Ren, G.1
Baritaki, S.2
Marathe, H.3
Feng, J.4
Park, S.5
Beach, S.6
Bazeley, P.S.7
Beshir, A.B.8
Fenteany, G.9
Mehra, R.10
Daignault, S.11
Al-Mulla, F.12
Keller, E.13
Bonavida, B.14
De La Serna, I.15
Yeung, K.C.16
-
27
-
-
79951810419
-
MicroRNA-101-mediated Akt activation and estrogen-independent growth
-
Sachdeva M, Wu H, Ru P, Hwang L, Trieu V, Mo YY: MicroRNA-101-mediated Akt activation and estrogen-independent growth. Oncogene 2011;30:822-831.
-
(2011)
Oncogene
, vol.30
, pp. 822-831
-
-
Sachdeva, M.1
Wu, H.2
Ru, P.3
Hwang, L.4
Trieu, V.5
Mo, Y.Y.6
-
28
-
-
78650643190
-
MicroRNA-101 targets MAPK phosphatase-1 to regulate the activation of MAPKs in macrophages
-
Zhu QY, Liu Q, Chen JX, Lan K, Ge BX: MicroRNA-101 targets MAPK phosphatase-1 to regulate the activation of MAPKs in macrophages. J Immunol 2010;185:7435-7442.
-
(2010)
J Immunol
, vol.185
, pp. 7435-7442
-
-
Zhu, Q.Y.1
Liu, Q.2
Chen, J.X.3
Lan, K.4
Ge, B.X.5
-
30
-
-
70949094349
-
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors
-
Hedvat M, Huszar D, Herrmann A, Gozgit JM, Schroeder A, Sheehy A, Buettner R, Proia D, Kowolik CM, Xin H, Armstrong B, Bebernitz G, Weng S, Wang L, Ye M, McEachern K, Chen H, Morosini D, Bell K, Alimzhanov M, Ioannidis S, McCoon P, Cao ZA, Yu H, Jove R, Zinda M: The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell 2009;16:487-497.
-
(2009)
Cancer Cell
, vol.16
, pp. 487-497
-
-
Hedvat, M.1
Huszar, D.2
Herrmann, A.3
Gozgit, J.M.4
Schroeder, A.5
Sheehy, A.6
Buettner, R.7
Proia, D.8
Kowolik, C.M.9
Xin, H.10
Armstrong, B.11
Bebernitz, G.12
Weng, S.13
Wang, L.14
Ye, M.15
McEachern, K.16
Chen, H.17
Morosini, D.18
Bell, K.19
Alimzhanov, M.20
Ioannidis, S.21
McCoon, P.22
Cao, Z.A.23
Yu, H.24
Jove, R.25
Zinda, M.26
more..
-
31
-
-
77950684805
-
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: Therapeutic implications for the treatment of myeloproliferative neoplasms
-
Quintas-Cardama A, Vaddi K, Liu P, Manshouri T, Li J, Scherle PA, Caulder E, Wen X, Li Y, Waeltz P, Rupar M, Burn T, Lo Y, Kelley J, Covington M, Shepard S, Rodgers JD, Haley P, Kantarjian H, Fridman JS, Verstovsek S: Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood 2010;115:3109-3117.
-
(2010)
Blood
, vol.115
, pp. 3109-3117
-
-
Quintas-Cardama, A.1
Vaddi, K.2
Liu, P.3
Manshouri, T.4
Li, J.5
Scherle, P.A.6
Caulder, E.7
Wen, X.8
Li, Y.9
Waeltz, P.10
Rupar, M.11
Burn, T.12
Lo, Y.13
Kelley, J.14
Covington, M.15
Shepard, S.16
Rodgers, J.D.17
Haley, P.18
Kantarjian, H.19
Fridman, J.S.20
Verstovsek, S.21
more..
|