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Volumn 59, Issue , 2014, Pages 9-16

Circulating tumor-cell detection and capture using microfluidic devices

Author keywords

Cancer therapy management; Circulating tumor cell (CTC); CTC capture; CTC detection; Dielectrophoresis; Early detection; Hydrodynamics; Metastases; Microfluidics; Nanotechnology

Indexed keywords

CELLS; DISEASES; ELECTROPHORESIS; HYDRODYNAMICS; NANOTECHNOLOGY; PATHOLOGY; TUMORS;

EID: 84904489230     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2014.02.017     Document Type: Review
Times cited : (113)

References (77)
  • 3
    • 84872760025 scopus 로고    scopus 로고
    • Circulating tumor cells: the substrate of personalized medicine?
    • Greene B.T., Hughes A.D., King M.R. Circulating tumor cells: the substrate of personalized medicine?. Front. Oncol 2012, 2:69.
    • (2012) Front. Oncol , vol.2 , pp. 69
    • Greene, B.T.1    Hughes, A.D.2    King, M.R.3
  • 4
    • 84872652204 scopus 로고    scopus 로고
    • Cornering metastases: therapeutic targeting of circulating tumor cells and stem cells
    • Faltas B. Cornering metastases: therapeutic targeting of circulating tumor cells and stem cells. Front. Oncol 2012, 2:68.
    • (2012) Front. Oncol , vol.2 , pp. 68
    • Faltas, B.1
  • 5
    • 79551693066 scopus 로고    scopus 로고
    • Circulating tumor cells: approaches to isolation and characterization
    • Yu M., Stott S., Toner M., Maheswaran S., Haber D.A. Circulating tumor cells: approaches to isolation and characterization. J. Cell Biol 2011, 192:373-382.
    • (2011) J. Cell Biol , vol.192 , pp. 373-382
    • Yu, M.1    Stott, S.2    Toner, M.3    Maheswaran, S.4    Haber, D.A.5
  • 6
  • 7
    • 84856971533 scopus 로고    scopus 로고
    • Fluid biopsy for circulating tumor cell identification in patients with early-and late-stage non-small cell lung cancer: a glimpse into lung cancer biology
    • Wendel M., Bazhenova L., Boshuizen R., Kolatkar A., Honnatti M., Cho E.H., et al. Fluid biopsy for circulating tumor cell identification in patients with early-and late-stage non-small cell lung cancer: a glimpse into lung cancer biology. Phys. Biol 2012, 9:016005.
    • (2012) Phys. Biol , vol.9 , pp. 016005
    • Wendel, M.1    Bazhenova, L.2    Boshuizen, R.3    Kolatkar, A.4    Honnatti, M.5    Cho, E.H.6
  • 9
    • 84868280268 scopus 로고    scopus 로고
    • Circulating tumor cells in non-small cell lung carcinoma
    • Boshuizen R., Kuhn P., van den Heuvel M. Circulating tumor cells in non-small cell lung carcinoma. J. Thorac. Dis 2012, 4:456-458.
    • (2012) J. Thorac. Dis , vol.4 , pp. 456-458
    • Boshuizen, R.1    Kuhn, P.2    van den Heuvel, M.3
  • 13
    • 32844474965 scopus 로고    scopus 로고
    • Estimation of Joule heating effect on temperature and pressure distribution in electrokinetic-driven microchannel flows
    • Chein R.Y., Yang Y.C., Lin Y.S. Estimation of Joule heating effect on temperature and pressure distribution in electrokinetic-driven microchannel flows. Electrophoresis 2006, 27:640-649.
    • (2006) Electrophoresis , vol.27 , pp. 640-649
    • Chein, R.Y.1    Yang, Y.C.2    Lin, Y.S.3
  • 14
    • 77955618032 scopus 로고    scopus 로고
    • Microfluidics platforms for single-cell analysis
    • Zare R.N., Kim S. Microfluidics platforms for single-cell analysis. Annu. Rev. Biomed. Eng 2010, 12:187-201.
    • (2010) Annu. Rev. Biomed. Eng , vol.12 , pp. 187-201
    • Zare, R.N.1    Kim, S.2
  • 15
  • 16
    • 84863792455 scopus 로고    scopus 로고
    • Nanobiotechnology for the capture and manipulation of circulating tumor cells
    • Hughes A.D., King M.R. Nanobiotechnology for the capture and manipulation of circulating tumor cells. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol 2012, 4:291-309.
    • (2012) Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol , vol.4 , pp. 291-309
    • Hughes, A.D.1    King, M.R.2
  • 17
    • 77956268304 scopus 로고    scopus 로고
    • Circulating tumour cells in cancer patients: challenges and perspectives
    • Pantel K., Alix-Panabieres C. Circulating tumour cells in cancer patients: challenges and perspectives. Trends Mol. Med 2010, 16:398-406.
    • (2010) Trends Mol. Med , vol.16 , pp. 398-406
    • Pantel, K.1    Alix-Panabieres, C.2
  • 19
    • 84877840356 scopus 로고    scopus 로고
    • Circulating tumor cells as therapy-related biomarkers in cancer patients
    • Gorges T.M., Pantel K. Circulating tumor cells as therapy-related biomarkers in cancer patients. Cancer Immunol. Immunother 2013, 62:931-939.
    • (2013) Cancer Immunol. Immunother , vol.62 , pp. 931-939
    • Gorges, T.M.1    Pantel, K.2
  • 20
    • 33645688204 scopus 로고    scopus 로고
    • HER2-positive circulating tumor cells indicate poor clinical outcome in stage I to III breast cancer patients
    • Wulfing P., Borchard J., Buerger H., Heidl S., Zanker K.S., Kiesel L., et al. HER2-positive circulating tumor cells indicate poor clinical outcome in stage I to III breast cancer patients. Clin. Cancer Res 2006, 12:1715-1720.
    • (2006) Clin. Cancer Res , vol.12 , pp. 1715-1720
    • Wulfing, P.1    Borchard, J.2    Buerger, H.3    Heidl, S.4    Zanker, K.S.5    Kiesel, L.6
  • 21
    • 84881555649 scopus 로고    scopus 로고
    • Towards a personalized breast cancer treatment approach guided by circulating tumor cell (CTC) characteristics
    • Onstenk W., Gratama J.W., Foekens J.A., Sleijfer S. Towards a personalized breast cancer treatment approach guided by circulating tumor cell (CTC) characteristics. Cancer Treat. Rev 2013, 39:691-700.
    • (2013) Cancer Treat. Rev , vol.39 , pp. 691-700
    • Onstenk, W.1    Gratama, J.W.2    Foekens, J.A.3    Sleijfer, S.4
  • 23
    • 84874993721 scopus 로고    scopus 로고
    • Microfluidic hydrodynamic cell separation: a review
    • Wu Z.H., Hjort K. Microfluidic hydrodynamic cell separation: a review. Micro Nanosyst 2009, 1:181-192.
    • (2009) Micro Nanosyst , vol.1 , pp. 181-192
    • Wu, Z.H.1    Hjort, K.2
  • 24
    • 33747771811 scopus 로고    scopus 로고
    • Continuous separation of particles using a microfluidic device equipped with flow rate control valves
    • Sai Y., Yamada M., Yasuda M., Seki M. Continuous separation of particles using a microfluidic device equipped with flow rate control valves. J. Chromatogr. A 2006, 1127:214-220.
    • (2006) J. Chromatogr. A , vol.1127 , pp. 214-220
    • Sai, Y.1    Yamada, M.2    Yasuda, M.3    Seki, M.4
  • 25
    • 34748893190 scopus 로고    scopus 로고
    • Microfluidic continuous particle/cell separation via electroosmotic-flow-tuned hydrodynamic spreading
    • Wu Z.G., Liu A.Q., Hjort K. Microfluidic continuous particle/cell separation via electroosmotic-flow-tuned hydrodynamic spreading. J. Micromech. Microeng 2007, 17:1992-1999.
    • (2007) J. Micromech. Microeng , vol.17 , pp. 1992-1999
    • Wu, Z.G.1    Liu, A.Q.2    Hjort, K.3
  • 26
    • 58149528188 scopus 로고    scopus 로고
    • Efficient microfluidic particle separation arrays
    • 013510
    • Inglis D.W. Efficient microfluidic particle separation arrays. Appl. Phys. Lett 2009, 94. 013510.
    • (2009) Appl. Phys. Lett , vol.94
    • Inglis, D.W.1
  • 27
    • 4544334667 scopus 로고    scopus 로고
    • Pinched flow fractionation: continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel
    • Yamada M., Nakashima M., Seki M. Pinched flow fractionation: continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel. Anal. Chem 2004, 76:5465-5471.
    • (2004) Anal. Chem , vol.76 , pp. 5465-5471
    • Yamada, M.1    Nakashima, M.2    Seki, M.3
  • 28
    • 70350464298 scopus 로고    scopus 로고
    • Inertial microfluidics
    • Di Carlo D. Inertial microfluidics. Lab Chip 2009, 9:3038-3046.
    • (2009) Lab Chip , vol.9 , pp. 3038-3046
    • Di Carlo, D.1
  • 29
    • 13244258475 scopus 로고    scopus 로고
    • Biomimetic autoseparation of leukocytes from whole blood in a microfluidic device
    • Shevkoplyas S.S., Yoshida T., Munn L.L., Bitensky M.W. Biomimetic autoseparation of leukocytes from whole blood in a microfluidic device. Anal. Chem 2005, 77:933-937.
    • (2005) Anal. Chem , vol.77 , pp. 933-937
    • Shevkoplyas, S.S.1    Yoshida, T.2    Munn, L.L.3    Bitensky, M.W.4
  • 31
    • 0033891393 scopus 로고    scopus 로고
    • Isolation by size of epithelial tumor cells - a new method for the immunomorphological and molecular characterization of circulating tumor cells
    • Vona G., Sabile A., Louha M., Sitruk V., Romana S., Schutze K., et al. Isolation by size of epithelial tumor cells - a new method for the immunomorphological and molecular characterization of circulating tumor cells. Am. J. Pathol 2000, 156:57-63.
    • (2000) Am. J. Pathol , vol.156 , pp. 57-63
    • Vona, G.1    Sabile, A.2    Louha, M.3    Sitruk, V.4    Romana, S.5    Schutze, K.6
  • 33
    • 34547529462 scopus 로고    scopus 로고
    • Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells
    • Zheng S., Lin H., Liu J.Q., Balic M., Datar R., Cote R.J., et al. Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells. J. Chromatogr. A 2007, 1162:154-161.
    • (2007) J. Chromatogr. A , vol.1162 , pp. 154-161
    • Zheng, S.1    Lin, H.2    Liu, J.Q.3    Balic, M.4    Datar, R.5    Cote, R.J.6
  • 34
    • 79751533744 scopus 로고    scopus 로고
    • 3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood
    • Zheng S.Y., Lin H.K., Lu B., Williams A., Datar R., Cote R.J., et al. 3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood. Biomed. Microdevices 2011, 13:203-213.
    • (2011) Biomed. Microdevices , vol.13 , pp. 203-213
    • Zheng, S.Y.1    Lin, H.K.2    Lu, B.3    Williams, A.4    Datar, R.5    Cote, R.J.6
  • 35
    • 77955149442 scopus 로고    scopus 로고
    • Size-selective microcavity array for rapid and efficient detection of circulating tumor cells
    • Hosokawa M., Hayata T., Fukuda Y., Arakaki A., Yoshino T., Tanaka T., et al. Size-selective microcavity array for rapid and efficient detection of circulating tumor cells. Anal. Chem 2010, 82:6629-6635.
    • (2010) Anal. Chem , vol.82 , pp. 6629-6635
    • Hosokawa, M.1    Hayata, T.2    Fukuda, Y.3    Arakaki, A.4    Yoshino, T.5    Tanaka, T.6
  • 36
    • 84879198321 scopus 로고    scopus 로고
    • Microcavity array system for size-based enrichment of circulating tumor cells from the blood of patients with small-cell lung cancer
    • Hosokawa M., Yoshikawa T., Negishi R., Yoshino T., Koh Y., Kenmotsu H., et al. Microcavity array system for size-based enrichment of circulating tumor cells from the blood of patients with small-cell lung cancer. Anal. Chem 2013, 85:5692-5698.
    • (2013) Anal. Chem , vol.85 , pp. 5692-5698
    • Hosokawa, M.1    Yoshikawa, T.2    Negishi, R.3    Yoshino, T.4    Koh, Y.5    Kenmotsu, H.6
  • 38
    • 37649022478 scopus 로고    scopus 로고
    • Continuous inertial focusing, ordering, and separation of particles in microchannels
    • Di Carlo D., Irimia D., Tompkins R.G., Toner M. Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:18892-18897.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 18892-18897
    • Di Carlo, D.1    Irimia, D.2    Tompkins, R.G.3    Toner, M.4
  • 39
    • 54349103530 scopus 로고    scopus 로고
    • Continuous particle separation in spiral microchannels using dean flows and differential migration
    • Bhagat A.A.S., Kuntaegowdanahalli S.S., Papautsky I. Continuous particle separation in spiral microchannels using dean flows and differential migration. Lab Chip 2008, 8:1906-1914.
    • (2008) Lab Chip , vol.8 , pp. 1906-1914
    • Bhagat, A.A.S.1    Kuntaegowdanahalli, S.S.2    Papautsky, I.3
  • 40
    • 68949151898 scopus 로고    scopus 로고
    • Differential inertial focusing of particles in curved low-aspect-ratio microchannels
    • Russom A., Gupta A.K., Nagrath S., Di Carlo D., Edd J.F., Toner M. Differential inertial focusing of particles in curved low-aspect-ratio microchannels. New J. Phys 2009, 11:075025.
    • (2009) New J. Phys , vol.11 , pp. 075025
    • Russom, A.1    Gupta, A.K.2    Nagrath, S.3    Di Carlo, D.4    Edd, J.F.5    Toner, M.6
  • 42
    • 84874672926 scopus 로고    scopus 로고
    • Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels
    • 011802
    • Sun J.S., Liu C., Li M.M., Wang J.D., Xianyu Y.L., Hu G.Q., et al. Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels. Biomicrofluidics 2013, 7. 011802.
    • (2013) Biomicrofluidics , vol.7
    • Sun, J.S.1    Liu, C.2    Li, M.M.3    Wang, J.D.4    Xianyu, Y.L.5    Hu, G.Q.6
  • 44
    • 37549002543 scopus 로고    scopus 로고
    • Isolation of rare circulating tumour cells in cancer patients by microchip technology
    • Nagrath S., Sequist L.V., Maheswaran S., Bell D.W., Irimia D., Ulkus L., et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 2007, 450:1235-1239.
    • (2007) Nature , vol.450 , pp. 1235-1239
    • Nagrath, S.1    Sequist, L.V.2    Maheswaran, S.3    Bell, D.W.4    Irimia, D.5    Ulkus, L.6
  • 45
    • 77951922478 scopus 로고    scopus 로고
    • Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody
    • Gleghorn J.P., Pratt E.D., Denning D., Liu H., Bander N.H., Tagawa S.T., et al. Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody. Lab Chip 2010, 10:27-29.
    • (2010) Lab Chip , vol.10 , pp. 27-29
    • Gleghorn, J.P.1    Pratt, E.D.2    Denning, D.3    Liu, H.4    Bander, N.H.5    Tagawa, S.T.6
  • 46
    • 70449103171 scopus 로고    scopus 로고
    • Three-Dimensional nanostructured substrates toward efficient capture of circulating tumor cells
    • Wang S.T., Wang H., Jiao J., Chen K.J., Owens G.E., Kamei K.I., et al. Three-Dimensional nanostructured substrates toward efficient capture of circulating tumor cells. Angew. Chem. Int. Ed. Engl 2009, 48:8970-8973.
    • (2009) Angew. Chem. Int. Ed. Engl , vol.48 , pp. 8970-8973
    • Wang, S.T.1    Wang, H.2    Jiao, J.3    Chen, K.J.4    Owens, G.E.5    Kamei, K.I.6
  • 47
    • 67651085393 scopus 로고    scopus 로고
    • Atomic force microscopy detects differences in the surface brush of normal and cancerous cells
    • Iyer S., Gaikwad R.M., Subba-Rao V., Woodworth C.D., Sokolov I. Atomic force microscopy detects differences in the surface brush of normal and cancerous cells. Nat. Nanotechnol 2009, 4:389-393.
    • (2009) Nat. Nanotechnol , vol.4 , pp. 389-393
    • Iyer, S.1    Gaikwad, R.M.2    Subba-Rao, V.3    Woodworth, C.D.4    Sokolov, I.5
  • 48
    • 84859895770 scopus 로고    scopus 로고
    • Biopolymer system for cell recovery from microfluidic cell capture devices
    • Shah A.M., Yu M., Nakamura Z., Ciciliano J., Ulman M., Kotz K., et al. Biopolymer system for cell recovery from microfluidic cell capture devices. Anal. Chem 2012, 84:3682-3688.
    • (2012) Anal. Chem , vol.84 , pp. 3682-3688
    • Shah, A.M.1    Yu, M.2    Nakamura, Z.3    Ciciliano, J.4    Ulman, M.5    Kotz, K.6
  • 50
    • 77954598808 scopus 로고    scopus 로고
    • Review article-dielectrophoresis: status of the theory, technology, and applications
    • 022811
    • Pethig R. Review article-dielectrophoresis: status of the theory, technology, and applications. Biomicrofluidics 2010, 4. 022811.
    • (2010) Biomicrofluidics , vol.4
    • Pethig, R.1
  • 54
    • 79952134859 scopus 로고    scopus 로고
    • Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP)
    • Moon H.S., Kwon K., Kim S.I., Han H., Sohn J., Lee S., et al. Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP). Lab Chip 2011, 11:1118-1125.
    • (2011) Lab Chip , vol.11 , pp. 1118-1125
    • Moon, H.S.1    Kwon, K.2    Kim, S.I.3    Han, H.4    Sohn, J.5    Lee, S.6
  • 56
    • 0037099408 scopus 로고    scopus 로고
    • Dielectrophoretic cell separation and gene expression profiling on microelectronic chip arrays
    • Huang Y., Joo S., Duhon M., Heller M., Wallace B., Xu X. Dielectrophoretic cell separation and gene expression profiling on microelectronic chip arrays. Anal. Chem 2002, 74:3362-3371.
    • (2002) Anal. Chem , vol.74 , pp. 3362-3371
    • Huang, Y.1    Joo, S.2    Duhon, M.3    Heller, M.4    Wallace, B.5    Xu, X.6
  • 57
    • 77954461631 scopus 로고    scopus 로고
    • Trapping single human osteoblast-like cells from a heterogeneous population using a dielectrophoretic microfluidic device
    • 022806
    • Thomas R.S.W., Mitchell P.D., Oreffo R.O.C., Morgan H. Trapping single human osteoblast-like cells from a heterogeneous population using a dielectrophoretic microfluidic device. Biomicrofluidics 2010, 4. 022806.
    • (2010) Biomicrofluidics , vol.4
    • Thomas, R.S.W.1    Mitchell, P.D.2    Oreffo, R.O.C.3    Morgan, H.4
  • 59
    • 70549110934 scopus 로고    scopus 로고
    • Contactless dielectrophoresis: a new technique for cell manipulation
    • Shafiee H., Caldwell J.L., Sano M.B., Davalos R.V. Contactless dielectrophoresis: a new technique for cell manipulation. Biomed. Microdevices 2009, 11:997-1006.
    • (2009) Biomed. Microdevices , vol.11 , pp. 997-1006
    • Shafiee, H.1    Caldwell, J.L.2    Sano, M.B.3    Davalos, R.V.4
  • 60
    • 80052826003 scopus 로고    scopus 로고
    • Selective concentration of human cancer cells using contactless dielectrophoresis
    • Henslee E.A., Sano M.B., Rojas A.D., Schmelz E.M., Davalos R.V. Selective concentration of human cancer cells using contactless dielectrophoresis. Electrophoresis 2011, 32:2523-2529.
    • (2011) Electrophoresis , vol.32 , pp. 2523-2529
    • Henslee, E.A.1    Sano, M.B.2    Rojas, A.D.3    Schmelz, E.M.4    Davalos, R.V.5
  • 61
    • 84863194825 scopus 로고    scopus 로고
    • ApoStream (TM), a new dielectrophoretic device for antibody independent isolation and recovery of viable cancer cells from blood
    • 024133
    • Gupta V., Jafferji I., Garza M., Melnikova V.O., Hasegawa D.K., Pethig R., et al. ApoStream (TM), a new dielectrophoretic device for antibody independent isolation and recovery of viable cancer cells from blood. Biomicrofluidics 2012, 6. 024133.
    • (2012) Biomicrofluidics , vol.6
    • Gupta, V.1    Jafferji, I.2    Garza, M.3    Melnikova, V.O.4    Hasegawa, D.K.5    Pethig, R.6
  • 62
    • 84874829102 scopus 로고    scopus 로고
    • High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidics platform by using optically-induced-dielectrophoretic (ODEP) force
    • Huang S.B., Wu M.H., Lin Y.H., Hsieh C.H., Yang C.L., Lin H.C., et al. High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidics platform by using optically-induced-dielectrophoretic (ODEP) force. Lab Chip 2013, 13:1371-1383.
    • (2013) Lab Chip , vol.13 , pp. 1371-1383
    • Huang, S.B.1    Wu, M.H.2    Lin, Y.H.3    Hsieh, C.H.4    Yang, C.L.5    Lin, H.C.6
  • 63
    • 77649237575 scopus 로고    scopus 로고
    • Separation of micro-particles utilizing spatial difference of optically induced dielectrophoretic forces
    • Lin W.Y., Lin Y.H., Lee G.B. Separation of micro-particles utilizing spatial difference of optically induced dielectrophoretic forces. Microfluid. Nanofluid 2010, 8:217-229.
    • (2010) Microfluid. Nanofluid , vol.8 , pp. 217-229
    • Lin, W.Y.1    Lin, Y.H.2    Lee, G.B.3
  • 64
    • 45149097339 scopus 로고    scopus 로고
    • Effects of dielectrophoresis on growth, viability and immuno-reactivity of listeria monocytogenes
    • Yang L., Banada P.P., Bhunia A.K., Bashir R. Effects of dielectrophoresis on growth, viability and immuno-reactivity of listeria monocytogenes. J. Biol. Eng 2008, 2:6.
    • (2008) J. Biol. Eng , vol.2 , pp. 6
    • Yang, L.1    Banada, P.P.2    Bhunia, A.K.3    Bashir, R.4
  • 65
    • 79956054109 scopus 로고    scopus 로고
    • Interdigitated comb-like electrodes for continuous separation of malignant cells from blood using dielectrophoresis
    • Alazzam A., Stiharu I., Bhat R., Meguerditchian A.N. Interdigitated comb-like electrodes for continuous separation of malignant cells from blood using dielectrophoresis. Electrophoresis 2011, 32:1327-1336.
    • (2011) Electrophoresis , vol.32 , pp. 1327-1336
    • Alazzam, A.1    Stiharu, I.2    Bhat, R.3    Meguerditchian, A.N.4
  • 67
    • 21144444795 scopus 로고    scopus 로고
    • Magnetic bead handling on-chip: new opportunities for analytical applications
    • Gijs M.A.M. Magnetic bead handling on-chip: new opportunities for analytical applications. Microfluid. Nanofluid 2004, 1:22-40.
    • (2004) Microfluid. Nanofluid , vol.1 , pp. 22-40
    • Gijs, M.A.M.1
  • 68
    • 33646742138 scopus 로고    scopus 로고
    • Microfluidic magnetic separator using an array of soft magnetic elements
    • Smistrup K., Lund-Olesen T., Hansen M.F., Tang P.T. Microfluidic magnetic separator using an array of soft magnetic elements. J. Appl. Phys 2006, 99:08p102.
    • (2006) J. Appl. Phys , vol.99
    • Smistrup, K.1    Lund-Olesen, T.2    Hansen, M.F.3    Tang, P.T.4
  • 69
    • 0034908432 scopus 로고    scopus 로고
    • An on-chip magnetic bead separator using spiral electromagnets with semi-encapsulated permalloy
    • Choi J.W., Liakopoulos T.M., Ahn C.H. An on-chip magnetic bead separator using spiral electromagnets with semi-encapsulated permalloy. Biosens. Bioelectron 2001, 16:409-416.
    • (2001) Biosens. Bioelectron , vol.16 , pp. 409-416
    • Choi, J.W.1    Liakopoulos, T.M.2    Ahn, C.H.3
  • 70
    • 4544350876 scopus 로고    scopus 로고
    • On-chip micro-electromagnets for magnetic-based bio-molecules separation
    • Ramadan Q., Samper V., Poenar D., Yu C. On-chip micro-electromagnets for magnetic-based bio-molecules separation. J. Magn. Magn. Mater 2004, 281:150-172.
    • (2004) J. Magn. Magn. Mater , vol.281 , pp. 150-172
    • Ramadan, Q.1    Samper, V.2    Poenar, D.3    Yu, C.4
  • 71
    • 77951682259 scopus 로고    scopus 로고
    • Selective breast cancer cell capture, culture, and immunocytochemical analysis using self-assembled magnetic bead patterns in a microfluidic chip
    • Sivagnanam V., Song B., Vandevyver C., Bunzli J.C.G., Gijs M.A.M. Selective breast cancer cell capture, culture, and immunocytochemical analysis using self-assembled magnetic bead patterns in a microfluidic chip. Langmuir 2010, 26:6091-6096.
    • (2010) Langmuir , vol.26 , pp. 6091-6096
    • Sivagnanam, V.1    Song, B.2    Vandevyver, C.3    Bunzli, J.C.G.4    Gijs, M.A.M.5
  • 72
    • 77957075043 scopus 로고    scopus 로고
    • Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays
    • Saliba A.E., Saias L., Psychari E., Minc N., Simon D., Bidard F.C., et al. Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:14524-14529.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 14524-14529
    • Saliba, A.E.1    Saias, L.2    Psychari, E.3    Minc, N.4    Simon, D.5    Bidard, F.C.6
  • 73
    • 84872680421 scopus 로고    scopus 로고
    • Albumin-coated monodisperse magnetic poly(glycidyl methacrylate) microspheres with immobilized antibodies: application to the capture of epithelial cancer cells
    • Horak D., Svobodova Z., Autebert J., Coudert B., Plichta Z., Kralovec K., et al. Albumin-coated monodisperse magnetic poly(glycidyl methacrylate) microspheres with immobilized antibodies: application to the capture of epithelial cancer cells. J. Biomed. Mater. Res. A 2013, 101A:23-32.
    • (2013) J. Biomed. Mater. Res. A , vol.101 , Issue.A , pp. 23-32
    • Horak, D.1    Svobodova, Z.2    Autebert, J.3    Coudert, B.4    Plichta, Z.5    Kralovec, K.6
  • 75
    • 84856742623 scopus 로고    scopus 로고
    • Clinically relevant microfluidic magnetophoretic isolation of rare-cell populations for diagnostic and therapeutic monitoring applications
    • Plouffe B.D., Mahalanabis M., Lewis L.H., Klapperich C.M., Murthy S.K. Clinically relevant microfluidic magnetophoretic isolation of rare-cell populations for diagnostic and therapeutic monitoring applications. Anal. Chem 2012, 84:1336-1344.
    • (2012) Anal. Chem , vol.84 , pp. 1336-1344
    • Plouffe, B.D.1    Mahalanabis, M.2    Lewis, L.H.3    Klapperich, C.M.4    Murthy, S.K.5
  • 76
    • 80155201503 scopus 로고    scopus 로고
    • Rare cell separation and analysis by magnetic sorting
    • Zborowski M., Chamers J.J. Rare cell separation and analysis by magnetic sorting. Anal. Chem 2011, 83:8050-8056.
    • (2011) Anal. Chem , vol.83 , pp. 8050-8056
    • Zborowski, M.1    Chamers, J.J.2
  • 77
    • 58249094045 scopus 로고    scopus 로고
    • Optimization of an enrichment process for circulating tumor cells from the blood of head and neck cancer patients through depletion of normal cells
    • Yang L.Y., Lang J.C., Balasubramanian P., Jatana K.R., Schuller D., Agrawal A., et al. Optimization of an enrichment process for circulating tumor cells from the blood of head and neck cancer patients through depletion of normal cells. Biotechnol. Bioeng 2009, 102:521-534.
    • (2009) Biotechnol. Bioeng , vol.102 , pp. 521-534
    • Yang, L.Y.1    Lang, J.C.2    Balasubramanian, P.3    Jatana, K.R.4    Schuller, D.5    Agrawal, A.6


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