Diffuse Desquamating Rash Following Exposure to Vancomycin-Impregnated Bone Cement

Annals of Pharmacotherapy

Volumn 48, Issue 8, 2014, Pages 1061-1065

  Williams, Brett ^a   Hanson, Amy ^a   Sha, Beverly ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

ABLC; arthroplasty; bone; cement; rash; Stevens Johnson; systemic; vancomycin

Indexed keywords

ANTIBIOTIC BONE CEMENT; BISACODYL; CEFADROXIL; CEFAZOLIN; CELECOXIB; CLONIDINE; DAPTOMYCIN; DOCUSATE SODIUM; DULOXETINE; HYDROCODONE; LABETALOL; LISINOPRIL; MORPHINE; ONDANSETRON; OXYCODONE; PARACETAMOL; PROCHLORPERAZINE; RIVAROXABAN; SIMVASTATIN; STEROID; TAMSULOSIN; UNCLASSIFIED DRUG; VANCOMYCIN; VANCOMYCIN BONE CEMENT;

ADULT; ARTICLE; CASE REPORT; DESQUAMATION; DRUG HYPERSENSITIVITY; HUMAN; KNEE ARTHROPLASTY; MALE; MEDICAL HISTORY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NOMOGRAM; PAIN; PRIORITY JOURNAL; PROSTHESIS INFECTION; RASH; SENNA; STEVENS JOHNSON SYNDROME;

EID: 84904473925     PISSN: 10600280     EISSN: 15426270     Source Type: Journal    
DOI: 10.1177/1060028014529547     Document Type: Article

References (25)

1. Widmer AF.New developments in diagnosis and treatment of infection in orthopedic implants.Clin Infect Dis. 2001;33:S94-S106.
2. Jacobs C,Christensen CP,Berend ME.Static and mobile antibiotic-impregnated cement spacers for the management of prosthetic joint infection.J Am Acad Orthop Surg. 2009;17:356-368.
3. Kalil GZ,Ernst EJ,Johnson SJ,et al.Systemic exposure to aminoglycosides following knee and hip arthroplasty with aminoglycoside-loaded bone cement implants.Ann Pharmacother. 2012;46:929-934.
4. Chohfi M,Langlais F,Fourastier J,Minet J,Thomazeau H,Cormier M.Pharmacokinetics, uses, and limitations of vancomycin-loaded bone cement.Int Orthop. 1998;22:171-177.
5. Bertazzoni Minelli E,Benini A,Magnan B,Bartolozzi P.Release of gentamicin and vancomycin from temporary human hip spacers in two-stage revision of infected arthroplasty.J Antimicrob Chemother. 2004;53:329-334.
6. Springer BD,Lee GC,Osmon D,Haidukewych GJ,Hanssen AD,Jacofsky DJ.Systemic safety of high-dose antibiotic-loaded cement spacers after resection of an infected total knee arthroplasty.Clin Orthop Relat Res. 2004;427:47-51.
7. Jones DH,Todd M,Craig TJ.Early diagnosis is key in vancomycin-induced linear IgA bullous dermatosis and Stevens-Johnson syndrome.J Am Osteopath Assoc. 2004;104:157-163.
8. Bohm NM,Wong JG.Bullous dermatosis associated with vancomycin extravasation.Am J Med Sci. 2012;343:177-179.
9. El-Naggari MA,Javad H,Chacko AP,Abdelmogheth AA.Intravenous immunoglobulin in the treatment of vancomycin-induced toxic epidermal necrolysis.Sultan Qaboos Univ Med J. 2013;13:132-136.
10. Alexander, Greenberger PA.Vancomycin-induced Stevens-Johnson syndrome.Allergy Asthma Proc. 1996;17:75-78.
11. Rocha JL,Kondo W,Baptista MI,Da Cunha CA,Martins LT.Uncommon vancomycin-induced side effects.Braz J Infect Dis. 2002;6:196-200.
12. Santaeugenia S,Pedro Botet ML,Sabat M,Sopena N,Sadria M.Stevens-Johnson syndrome associated with vancomcyn [in Spanish].Rev Esp Quimioter. 2000;13:425-426.
13. Laurencin CT,Horan RF,Senatus PB,Wheeler CB,Lipson SJ.Stevens-Johnson-type reaction with vancomycin treatment.Ann Pharmacother. 1992;26:1520-1521.
14. Neal D,Morton R,Bailie GR,Waldek S.Exfoliative reaction to vancomycin.Br Med J (Clin Res Ed). 1988;296:137.
15. Gilmore ES,Friedman JS,Morrell DS.Extensive fixed drug eruption secondary to vancomycin.Pediatr Dermatol. 2004;21:600.
16. Naranjo CA,Busto U,Sellers EM,et al.A method for estimating the probability of adverse drug reactions.Clin Pharmacol Ther. 1981;30:239-245.
17. Dovas S,Liakopoulos V,Papatheodorou L,et al.Acute renal failure after antibiotic-impregnated bone cement treatment of an infected total knee arthroplasty.Clin Nephrol. 2008;69:207-212.
18. Patrick BN,Rivey MP,Allington DR.Acute renal failure associated with vancomycin- and tobramycin-laden cement in total hip arthroplasty.Ann Pharmacother. 2006;40:2037-2042.
19. McGlothan KR,Gosmanova EO.A case report of acute interstitial nephritis associated with antibiotic-impregnated orthopedic bone-cement spacer.Tenn Med. 2012;105:37 42-40.
20. Menge TJ,Koethe JR,Jenkins CA,et al.Acute kidney injury after placement of an antibiotic-impregnated cement spacer during revision total knee arthroplasty.J Arthroplasty. 2012;27:1221-1227.
21. Van Raaij TM,Visser LE,Vulto AG,Verhaar JA.Acute renal failure after local gentamicin treatment in an infected total knee arthroplasty.J Arthroplasty. 2002;17:948-950.
22. De Klaver PA,Koning JD,Janssen RP,Derijks LJ.High systemic gentamicin levels and ototoxicity after implantation of gentamicin beads in a 70-year-old man: a case report.Acta Orthop. 2009;80:734-736.
23. Haeberle M,Wittner B.Is gentamicin-loaded bone cement a risk for developing systemic allergic dermatitis?.Contact Dermatitis. 2009;60:176-177.
24. Song EK,Seon JK,Jeong MS.Delayed-type hypersensitivity reaction to piperacillin/tazobactam in a patient with an infected total knee replacement.J Bone Joint Surg Br. 2010;92:1596-1599.
25. Park HB,Choi JS,Park SH,Kee WJ,Koh YI.Drug fever due to piperacillin/tazobactam loaded into bone cement.J Korean Med Sci. 2011;26:301-303.