In situ synthesis of peptide nucleic acids in porous silicon for drug delivery and biosensing

Bioconjugate Chemistry

Volumn 25, Issue 7, 2014, Pages 1192-1197

  Beavers, Kelsey R ^a   Mares, Jeremy W ^a   Swartz, Caleb M ^b   Zhao, Yiliang ^a   Weiss, Sharon M ^a   Duvall, Craig L ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b LaVergne High School   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; GENE THERAPY; MASS SPECTROMETRY; NONDESTRUCTIVE EXAMINATION; NUCLEIC ACIDS; OPTICAL DATA PROCESSING; POROUS SILICON; TARGETED DRUG DELIVERY;

BIOSENSING; IN-SITU SYNTHESIS; NON DESTRUCTIVE; OPTICAL MEASUREMENT; PEPTIDE BACKBONES; PEPTIDE NUCLEIC ACID; POROUS SILICON FILMS; POROUS SILICON SUBSTRATES; SYNTHETIC MOLECULES; VERSATILE METHODS;

CONTROLLED DRUG DELIVERY;

3 AMINOPROPYLTRIETHOXYSILANE; COMPLEMENTARY DNA; MICRORNA; NANOPARTICLE; PEPTIDE NUCLEIC ACID; PHOSPHATE BUFFERED SALINE; SILICON; AMINO-PROPYL-TRIETHOXYSILANE; DNA; MIRN122 MICRORNA, HUMAN; PROPYLAMINE; SILANE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; CONJUGATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GENE THERAPY; GENETIC PROCEDURES; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYBRIDIZATION; LIVER CELL CARCINOMA; MASS SPECTROMETRY; OPTICS; SURFACE PROPERTY; SYNTHESIS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; GENETICS; LIVER TUMOR; METABOLISM; NUCLEIC ACID HYBRIDIZATION; POROSITY; PROCEDURES; TUMOR CELL CULTURE;

BIOSENSING TECHNIQUES; CARCINOMA, HEPATOCELLULAR; DNA; DRUG DELIVERY SYSTEMS; HUMANS; LIVER NEOPLASMS; MASS SPECTROMETRY; MICRORNAS; NANOPARTICLES; NUCLEIC ACID HYBRIDIZATION; PEPTIDE NUCLEIC ACIDS; POROSITY; PROPYLAMINES; SILANES; SILICON; TUMOR CELLS, CULTURED;

EID: 84904414333     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc5001092     Document Type: Article

References (37)

1. Nielsen, P. E., Egholm, M., Berg, R. H., and Buchardt, O. (1991) Sequence-selective recognition of dna by strand displacement with a thymine-substituted polyamide Science 254 (5037) 1497-1500
2. Braasch, D. A. and Corey, D. R. (2001) Synthesis, analysis, purification, and intracellular delivery of peptide nucleic acids Methods 23 (2) 97-107
3. Egholm, M., Buchardt, O., Christensen, L., Behrens, C., Freier, S. M., Driver, D. A., Berg, R. H., Kim, S. K., Norden, B., and Nielsen, P. E. (1993) PNA hybridizes to complementary oligonucleotides obeying the watson-crick hydrogen-bonding rules Nature 365 (6446) 566-568
4. Ratilainen, T., Holmen, A., Tuite, E., Nielsen, P. E., and Norden, B. (2000) Thermodynamics of sequence-specific binding of PNA to DNA Biochemistry 39 (26) 7781-7791
5. Demidov, V., Frankkamenetskii, M. D., Egholm, M., Buchardt, O., and Nielsen, P. E. (1993) Sequence selective double-strand DNA cleavage by peptide nucleic-acid (PNA) targeting using nuclease S1 Nucleic Acids Res. 21 (9) 2103-2107
6. Demidov, V. V., Potaman, V. N., Frank-Kamenetskil, M., Egholm, M., Buchard, O., Sönnichsen, S. H., and Nlelsen, P. E. (1994) Stability of peptide nucleic acids in human serum and cellular extracts Biochem. Pharmacol. 48 (6) 1310-1313
7. Nielsen, P. E. (1999) Applications of peptide nucleic acids Curr. Opin. Biotechnol. 10 (1) 71-75
8. Larsen, H. J., Bentin, T., and Nielsen, P. E. (1999) Antisense properties of peptide nucleic acid BBA Gene Struct. Expr. 1489 (1) 159-166
9. Oh, S. Y., Ju, Y., and Park, H. (2009) A highly effective and long-lasting inhibition of miRNAs with PNA-based antisense oligonucleotides Mol. Cells 28 (4) 341-345
10. Briones, C. and Moreno, M. (2012) Applications of peptide nucleic acids (PNAs) and locked nucleic acids (LNAs) in biosensor development Anal. Bioanal. Chem. 402 (10) 3071-3089
11. Fabbri, E., Brognara, E., Borgatti, M., Lampronti, I., Finotti, A., Bianchi, N., Sforza, S., Tedeschi, T., Manicardi, A., Marchelli, R., Corradini, R., and Gambari, R. (2011) miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs Epigenomics 3 (6) 733-745
12. Wang, J., Palecek, E., Nielsen, P. E., Rivas, G., Cai, X., Shiraishi, H., Dontha, N., Luo, D., and Farias, P. A. M. (1996) Peptide nucleic acid probes for sequence-specific DNA biosensors J. Am. Chem. Soc. 118 (33) 7667-7670
13. Wittung, P., Kajanus, J., Edwards, K., Nielsen, P., Nordén, B., and Malmström, B. G. (1995) Phospholipid membrane permeability of peptide nucleic acid FEBS Lett. 365 (1) 27-29
14. Lennox, K. A. and Behlke, M. A. (2011) Chemical modification and design of anti-miRNA oligonucleotides Gene Ther. 18 (12) 1111-1120
15. Fang, H., Zhang, K., Shen, G., Wooley, K. L., and Taylor, J.-S. A. (2009) Cationic shell-cross-linked knedel-like (cSCK) nanoparticles for highly efficient PNA delivery Mol. Pharmaceutics 6 (2) 615-626
16. Mehiri, M., Upert, G., Tripathi, S., Di Giorgio, A., Condom, R., Pandey, V. N., and Patino, N. (2008) An efficient biodelivery system for antisense polyamide nucleic acid (PNA) Oligonucleotides 18 (3) 245-255
17. Tanaka, T., Godin, B., Bhavane, R., Nieves-Alicea, R., Gu, J., Liu, X., Chiappini, C., Fakhoury, J. R., Amra, S., and Ewing, A. (2010) In vivo evaluation of safety of nanoporous silicon carriers following single and multiple dose intravenous administrations in mice Int. J. Pharm. 402 (1-2) 190-197
18. Anglin, E., Cheng, L., Freeman, W., and Sailor, M. (2008) Porous silicon in drug delivery devices and materials Adv. Drug Delivery Rev. 60 (11) 1266-1277
19. Pacholski, C. (2013) Photonic crystal sensors based on porous silicon Sensors 13 (4) 4694-4713
20. Jane, A., Dronov, R., Hodges, A., and Voelcker, N. H. (2009) Porous silicon biosensors on the advance Trends Biotechnol. 27 (4) 230-239
21. Kashanian, S., Harding, F., Irani, Y., Klebe, S., Marshall, K., Loni, A., Canham, L., Fan, D., Williams, K. A., Voelcker, N. H., and Coffer, J. L. (2010) Evaluation of mesoporous silicon/polycaprolactone composites as ophthalmic implants Acta Biomater. 6 (9) 3566-3572
22. Archer, M., Christophersen, M., and Fauchet, P. (2004) Macroporous silicon electrical sensor for DNA hybridization detection Biomed. Microdevices 6 (3) 203-211
23. Furbert, P., Lu, C., Winograd, N., and DeLouise, L. (2008) Label-free optical detection of peptide synthesis on a porous silicon scaffold/sensor Langmuir 24 (6) 2908-2915
24. Sullivan, T. P., van Poll, M. L., Dankers, P. Y. W., and Huck, W. T. S. (2004) Forced peptide synthesis in nanoscale confinement under elastomeric stamps Angew. Chem. 116 (32) 4286-4289
25. McInnes, S. J. and Voelcker, N. (2012) Porous silicon-based nanostructured microparticles as degradable supports for solid-phase synthesis and release of oligonucleotides Nanoscale Res. Lett. 7 (1) 385
26. Lawrie, J. L., Xu, Z., Rong, G., Laibinis, P. E., and Weiss, S. M. (2009) Synthesis of DNA oligonucleotides in mesoporous silicon Phys. Status Solidi A 206 (6) 1339-1342
27. Torres, A. G., Fabani, M. M., Vigorito, E., Williams, D., Al-Obaidi, N., Wojciechowski, F., Hudson, R. H. E., Seitz, O., and Gait, M. J. (2012) Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs Nucleic Acids Res. 40 (5) 2152-2167
28. Jopling, C. L., Yi, M., Lancaster, A. M., Lemon, S. M., and Sarnow, P. (2005) Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA Science 309 (5740) 1577-1581
29. Padmanabhan, S., Coughlin, J., and Iyer, R. (2005) Microwave-assisted functionalisation of solid supports: application in the rapid loading of nucleosides on controlled-pore-glass (CPG) Tetrahedron Lett. 46, 343-347
30. Lawrie, J. L., Jiao, Y., and Weiss, S. M. (2010) Size-dependent infiltration and optical detection of nucleic acids in nanoscale pores IEEE Trans. Nanotechnol. 9 (5) 596-602
31. Rasmussen, H., Liljefors, T., Petersson, B., Nielsen, P. E., and Kastrup, J. S. (2004) The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals J. Biomol. Struct. Dyn. 21 (4) 495-502
32. Gaur, G., Koktysh, D. S., and Weiss, S. M. (2013) Immobilization of quantum dots in nanostructured porous silicon films: characterizations and signal amplification for dual-mode optical biosensing Adv. Funct. Mater. 23 (29) 3604-3614
33. Filipe, V., Hawe, A., and Jiskoot, W. (2010) Critical evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregates Pharm. Res. 27 (5) 796-810
34. Hutvágner, G., Simard, M. J., Mello, C. C., and Zamore, P. D. (2004) Sequence-specific inhibition of small RNA function PLoS Biol. 2 (4) e98
35. Connelly, C. M., Thomas, M., and Deiters, A. (2012) High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function J. Biomol. Screen. 17 (6) 822-828
36. Santos, H. A., Riikonen, J., Salonen, J., Mäkilä, E., Heikkilä, T., Laaksonen, T., Peltonen, L., Lehto, V.-P., and Hirvonen, J. (2010) In vitro cytotoxicity of porous silicon microparticles: Effect of the particle concentration, surface chemistry and size Acta Biomater. 6 (7) 2721-2731
37. Zourob, M. (2010) Recognition Receptors in Biosensors, Springer.