Panax notoginseng saponins improve erectile function through attenuation of oxidative stress, restoration of akt activity and protection of endothelial and smooth muscle cells in diabetic rats with erectile dysfunction

Urologia Internationalis

Volumn 93, Issue 1, 2014, Pages 92-99

  Li, Huan ^a   He, Wei Yang ^a   Lin, Fan ^a   Gou, Xin ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Diabetes mellitus; Erectile dysfunction; Oxidative stress; Panax notoginseng saponins; Smooth muscle cells

Indexed keywords

GLUTATHIONE; MALONALDEHYDE; PANAX NOTOGINSENG EXTRACT; PROTEIN KINASE B; SAPONIN DERIVATIVE; SUPEROXIDE DISMUTASE; ANTIOXIDANT; PLANT EXTRACT; SAPONIN; APOMORPHINE; CYTOPROTECTIVE AGENT; GLUCOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; ELECTRON MICROSCOPY; ELECTROSTIMULATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ERECTILE DYSFUNCTION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OXIDATIVE STRESS; PANAX NOTOGINSENG; PENIS ERECTION; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; THROMBUS; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM; ANIMAL; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; HUMAN; METABOLISM; PENIS; SPRAGUE DAWLEY RAT; CELL STRUCTURE; CHINESE MEDICINE; COMPARATIVE STUDY; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; LOW DRUG DOSE; MALE GENITAL SYSTEM FUNCTION; RANDOMIZED CONTROLLED TRIAL; WEIGHT GAIN;

ANIMALS; ANTIOXIDANTS; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ERECTILE DYSFUNCTION; GLUTATHIONE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MALONDIALDEHYDE; MICROSCOPY, ELECTRON; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PANAX NOTOGINSENG; PENIS; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS; SUPEROXIDE DISMUTASE;

EID: 84904396037     PISSN: 00421138     EISSN: 14230399     Source Type: Journal    
DOI: 10.1159/000354878     Document Type: Article

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