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Volumn 47, Issue 4, 2012, Pages 397-403

DRD2 C957T and taqia Genotyping Reveals Gender Effects and Unique Low-Risk and High-Risk Genotypes in Alcohol Dependence

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR;

EID: 84863992954     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/ags047     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 15544371357 scopus 로고    scopus 로고
    • WINPEPI (PEPI-for-Windows): computer programs for epidemiologists
    • Abramson JH. (2004) WINPEPI (PEPI-for-Windows): computer programs for epidemiologists. Epidemiol Perspect Innov 1:6.
    • (2004) Epidemiol Perspect Innov , vol.1 , pp. 6
    • Abramson, J.H.1
  • 2
    • 0034743605 scopus 로고    scopus 로고
    • No association between the dopamine D2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteria
    • Anghelescu I, Germeyer S, Muller MJ et al. (2001) No association between the dopamine D2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteria. Alcohol Clin Exp Res 25:805-9.
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 805-809
    • Anghelescu, I.1    Germeyer, S.2    Muller, M.J.3
  • 3
    • 33748783607 scopus 로고    scopus 로고
    • The taqI DRD2 A1 allele is associated with alcohol-dependence although its effect size is small
    • Berggren U, Fahlke C, Aronsson E et al. (2006) The taqI DRD2 A1 allele is associated with alcohol-dependence although its effect size is small. Alcohol Alcohol 41:479-85.
    • (2006) Alcohol Alcohol , vol.41 , pp. 479-485
    • Berggren, U.1    Fahlke, C.2    Aronsson, E.3
  • 4
    • 0025275767 scopus 로고
    • Allelic association of human dopamine D2 receptor gene in alcoholism
    • Blum K, Noble EP, Sheridan PJ et al. (1990) Allelic association of human dopamine D2 receptor gene in alcoholism. J Am Med Assoc 263:2055-60.
    • (1990) J Am Med Assoc , vol.263 , pp. 2055-2060
    • Blum, K.1    Noble, E.P.2    Sheridan, P.J.3
  • 5
    • 0034530331 scopus 로고    scopus 로고
    • Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors
    • Blum K, Braverman ER, Holder JM et al. (2000) Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors. J Psychoactive Drugs 32(Suppl. i-iv):1-112.
    • (2000) J Psychoactive Drugs , vol.32 , Issue.SUPPL. I-IV , pp. 1-112
    • Blum, K.1    Braverman, E.R.2    Holder, J.M.3
  • 6
    • 0019414006 scopus 로고
    • Dopamine receptor binding in inbred mice: strain differences in mesolimbic and nigrostriatal dopamine binding sites
    • Boehme RE, Ciaranello RD. (1981) Dopamine receptor binding in inbred mice: strain differences in mesolimbic and nigrostriatal dopamine binding sites. Proc Natl Acad Sci USA 78:3255-9.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 3255-3259
    • Boehme, R.E.1    Ciaranello, R.D.2
  • 8
    • 70350696195 scopus 로고    scopus 로고
    • Introduction to the special issue of alcohol and alcoholism on sex/gender differences in responses to alcohol
    • Devaud LL, Prendergast MA. (2009) Introduction to the special issue of alcohol and alcoholism on sex/gender differences in responses to alcohol. Alcohol Alcohol 44:533-4.
    • (2009) Alcohol Alcohol , vol.44 , pp. 533-534
    • Devaud, L.L.1    Prendergast, M.A.2
  • 9
    • 0037320652 scopus 로고    scopus 로고
    • Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor
    • Duan J, Wainwright MS, Comeron JM et al. (2003) Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor. Hum Mol Genet 12:205-16.
    • (2003) Hum Mol Genet , vol.12 , pp. 205-216
    • Duan, J.1    Wainwright, M.S.2    Comeron, J.M.3
  • 10
    • 0027335779 scopus 로고
    • Effects of D1 and D2 dopamine receptor agents on ethanol consumption in the high-alcohol-drinking (HAD) line of rats
    • Dyr W, McBride WJ, Lumeng L et al. (1993) Effects of D1 and D2 dopamine receptor agents on ethanol consumption in the high-alcohol-drinking (HAD) line of rats. Alcohol 10:207-12.
    • (1993) Alcohol , vol.10 , pp. 207-212
    • Dyr, W.1    McBride, W.J.2    Lumeng, L.3
  • 11
    • 36048939114 scopus 로고    scopus 로고
    • Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning
    • Frank MJ, Moustafa AA, Haughey HM et al. (2007) Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning. Proc Natl Acad Sci USA 104:16311-6.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16311-16316
    • Frank, M.J.1    Moustafa, A.A.2    Haughey, H.M.3
  • 12
    • 2942522762 scopus 로고    scopus 로고
    • The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States 1991-1992 and 2001-2002
    • Grant BF, Dawson DA, Stinson FS et al. (2004) The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002. Drug Alcohol Depend 74:223-34.
    • (2004) Drug Alcohol Depend , vol.74 , pp. 223-234
    • Grant, B.F.1    Dawson, D.A.2    Stinson, F.S.3
  • 13
    • 0021245430 scopus 로고
    • The dopamine/neuroleptic receptor
    • Grigoriadis D, Seeman P. (1984) The dopamine/neuroleptic receptor. Can J Neurol Sci 11:108-13.
    • (1984) Can J Neurol Sci , vol.11 , pp. 108-113
    • Grigoriadis, D.1    Seeman, P.2
  • 14
    • 34248183399 scopus 로고    scopus 로고
    • Betweenand within-family association test of the dopamine receptor D2 TaqIA polymorphism and alcohol abuse and dependence in a general population sample of adults
    • Haberstick BC, Timberlake D, Smolen A et al. (2007) Betweenand within-family association test of the dopamine receptor D2 TaqIA polymorphism and alcohol abuse and dependence in a general population sample of adults. J Stud Alcohol Drugs 68:362-70.
    • (2007) J Stud Alcohol Drugs , vol.68 , pp. 362-370
    • Haberstick, B.C.1    Timberlake, D.2    Smolen, A.3
  • 15
    • 23344439020 scopus 로고    scopus 로고
    • Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients
    • Heinz A, Siessmeier T, Wrase J et al. (2005) Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients. Am J Psychiatry 162:1515-20.
    • (2005) Am J Psychiatry , vol.162 , pp. 1515-1520
    • Heinz, A.1    Siessmeier, T.2    Wrase, J.3
  • 16
    • 45149106758 scopus 로고    scopus 로고
    • Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families
    • Hill SY, Hoffman EK, Zezza N et al. (2008) Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families. Am J Med Genet Part B 147B:517-26.
    • (2008) Am J Med Genet Part B , vol.147 B , pp. 517-526
    • Hill, S.Y.1    Hoffman, E.K.2    Zezza, N.3
  • 17
    • 9644283721 scopus 로고    scopus 로고
    • C957T polymorphism of the dopamine D2 receptor (DRD2) gene affects striatal DRD2 availability in vivo
    • 1060-1 Erratum
    • Hirvonen M, Laakso A, Nagren K et al. (2004) C957T polymorphism of the dopamine D2 receptor (DRD2) gene affects striatal DRD2 availability in vivo. Mol Psychiatry 9:1060-1, Erratum 10:889.
    • (2004) Mol Psychiatry , vol.9 , pp. 889
    • Hirvonen, M.1    Laakso, A.2    Nagren, K.3
  • 18
    • 0035146176 scopus 로고    scopus 로고
    • Sex differences in extrastriatal dopamine d(2)-like receptors in the human brain
    • Kaasinen V, Nagren K, Hietala J et al. (2001) Sex differences in extrastriatal dopamine d(2)-like receptors in the human brain. Am J Psychiatry 158:308-11.
    • (2001) Am J Psychiatry , vol.158 , pp. 308-311
    • Kaasinen, V.1    Nagren, K.2    Hietala, J.3
  • 19
    • 0028937950 scopus 로고
    • Bromocriptine in the treatment of alcoholics with the D2 dopamine receptor A1 allele
    • Lawford BR, Young RM, Rowell JA et al. (1995) Bromocriptine in the treatment of alcoholics with the D2 dopamine receptor A1 allele. Nat Med 1:337-41.
    • (1995) Nat Med , vol.1 , pp. 337-341
    • Lawford, B.R.1    Young, R.M.2    Rowell, J.A.3
  • 20
    • 0031568339 scopus 로고    scopus 로고
    • Association of the D2 dopamine receptor A1 allele with alcoholism: medical severity of alcoholism and type of controls
    • Lawford BR, Young RM, Rowell JA et al. (1997) Association of the D2 dopamine receptor A1 allele with alcoholism: medical severity of alcoholism and type of controls. Biol Psychiatry 41:386-93.
    • (1997) Biol Psychiatry , vol.41 , pp. 386-393
    • Lawford, B.R.1    Young, R.M.2    Rowell, J.A.3
  • 21
    • 9644272541 scopus 로고    scopus 로고
    • The C/C genotype of the C957T polymorphism of the dopamine D2 receptor is associated with schizophrenia
    • Lawford BR, Young RM, Swagell CD et al. (2005) The C/C genotype of the C957T polymorphism of the dopamine D2 receptor is associated with schizophrenia. Schizophr Res 73:31-7.
    • (2005) Schizophr Res , vol.73 , pp. 31-37
    • Lawford, B.R.1    Young, R.M.2    Swagell, C.D.3
  • 22
    • 61449155496 scopus 로고    scopus 로고
    • Genetics of dopamine receptors and drug addiction: a comprehensive review
    • Le Foll B, Gallo A, Le Strat Y et al. (2009) Genetics of dopamine receptors and drug addiction: a comprehensive review. Behav Pharmacol 20:1-17.
    • (2009) Behav Pharmacol , vol.20 , pp. 1-17
    • Le Foll, B.1    Gallo, A.2    Le Strat, Y.3
  • 23
    • 0036838077 scopus 로고    scopus 로고
    • Male limited association of the dopamine receptor D2 gene TaqI a polymorphism and alcohol dependence
    • Limosin F, Gorwood P, Loze JY et al. (2002) Male limited association of the dopamine receptor D2 gene TaqI a polymorphism and alcohol dependence. Am J Med Genet 112:343-6.
    • (2002) Am J Med Genet , vol.112 , pp. 343-346
    • Limosin, F.1    Gorwood, P.2    Loze, J.Y.3
  • 24
    • 61849157391 scopus 로고    scopus 로고
    • Gender effect on association between DRD2 polymorphism and substance dependence in a Spanish sample
    • Lopez-Castroman J, Vaquero-Lorenzo C, Perez-Rodriguez MM et al. (2009) Gender effect on association between DRD2 polymorphism and substance dependence in a Spanish sample. Drug Alcohol Depend 101:210-2.
    • (2009) Drug Alcohol Depend , vol.101 , pp. 210-212
    • Lopez-Castroman, J.1    Vaquero-Lorenzo, C.2    Perez-Rodriguez, M.M.3
  • 25
    • 27944446443 scopus 로고    scopus 로고
    • Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum
    • Martinez D, Gil R, Slifstein M et al. (2005) Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Biol Psychiatry 58:779-86.
    • (2005) Biol Psychiatry , vol.58 , pp. 779-786
    • Martinez, D.1    Gil, R.2    Slifstein, M.3
  • 26
    • 0027337471 scopus 로고
    • Densities of dopamine D2 receptors are reduced in CNS regions of alcoholpreferring P rats
    • McBride WJ, Chernet E, Dyr W et al. (1993) Densities of dopamine D2 receptors are reduced in CNS regions of alcoholpreferring P rats. Alcohol 10:387-90.
    • (1993) Alcohol , vol.10 , pp. 387-390
    • McBride, W.J.1    Chernet, E.2    Dyr, W.3
  • 27
    • 34247542196 scopus 로고    scopus 로고
    • Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias
    • Munafo MR, Matheson IJ, Flint J. (2007) Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias. Mol Psychiatry 12:454-61.
    • (2007) Mol Psychiatry , vol.12 , pp. 454-461
    • Munafo, M.R.1    Matheson, I.J.2    Flint, J.3
  • 28
    • 2642572803 scopus 로고    scopus 로고
    • Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23 1
    • Neville MJ, Johnstone EC, Walton RT. (2004) Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1. Hum Mutat 23:540-5.
    • (2004) Hum Mutat , vol.23 , pp. 540-545
    • Neville, M.J.1    Johnstone, E.C.2    Walton, R.T.3
  • 30
    • 58149348752 scopus 로고    scopus 로고
    • Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood
    • Perkins KA, Lerman C, Grottenthaler A et al. (2008) Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behav Pharmacol 19:641-9.
    • (2008) Behav Pharmacol , vol.19 , pp. 641-649
    • Perkins, K.A.1    Lerman, C.2    Grottenthaler, A.3
  • 31
    • 0031800342 scopus 로고    scopus 로고
    • Sex differences in the striatal dopamine D2 receptor binding characteristics in vivo
    • Pohjalainen T, Rinne JO, Nagren K et al. (1998) Sex differences in the striatal dopamine D2 receptor binding characteristics in vivo. Am J Psychiatry 155:768-73.
    • (1998) Am J Psychiatry , vol.155 , pp. 768-773
    • Pohjalainen, T.1    Rinne, J.O.2    Nagren, K.3
  • 32
    • 49149083960 scopus 로고    scopus 로고
    • DRD2 and ANKK1 genotype in alcohol-dependent patients with psychopathic traits: association and interaction study
    • Ponce G, Hoenicka J, Jimenez-Arriero MA et al. (2008) DRD2 and ANKK1 genotype in alcohol-dependent patients with psychopathic traits: association and interaction study. Br J Psychiatry 193:121-5.
    • (2008) Br J Psychiatry , vol.193 , pp. 121-125
    • Ponce, G.1    Hoenicka, J.2    Jimenez-Arriero, M.A.3
  • 33
    • 70349728521 scopus 로고    scopus 로고
    • The ANKK1 kinase gene and psychiatric disorders
    • Ponce G, Perez-Gonzalez R, Aragues M et al. (2009) The ANKK1 kinase gene and psychiatric disorders. Neurotox Res 16:50-9.
    • (2009) Neurotox Res , vol.16 , pp. 50-59
    • Ponce, G.1    Perez-Gonzalez, R.2    Aragues, M.3
  • 34
    • 33745975803 scopus 로고    scopus 로고
    • Genetics and alcoholism: how close are we to potential clinical applications?
    • Quickfall J, el-Guebaly N. (2006) Genetics and alcoholism: how close are we to potential clinical applications? Can J Psychiatry 51:461-7.
    • (2006) Can J Psychiatry , vol.51 , pp. 461-467
    • Quickfall, J.1    el-Guebaly, N.2
  • 35
    • 0033256886 scopus 로고    scopus 로고
    • Dopamine transporter and D2-receptor density in late-onset alcoholism
    • Repo E, Kuikka JT, Bergstrom KA et al. (1999) Dopamine transporter and D2-receptor density in late-onset alcoholism. Psychopharmacology 147:314-8.
    • (1999) Psychopharmacology , vol.147 , pp. 314-318
    • Repo, E.1    Kuikka, J.T.2    Bergstrom, K.A.3
  • 36
    • 70450196497 scopus 로고    scopus 로고
    • Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: data from an association study
    • Saiz PA, Garcia-Portilla MP, Florez G et al. (2009) Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: data from an association study. Alcohol Clin Exp Res 33:2147-53.
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 2147-2153
    • Saiz, P.A.1    Garcia-Portilla, M.P.2    Florez, G.3
  • 37
    • 38349193139 scopus 로고    scopus 로고
    • Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: a HuGE gene-disease association review
    • Smith L, Watson M, Gates S et al. (2008) Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: a HuGE gene-disease association review. Am J Epidemiol 167:125-38.
    • (2008) Am J Epidemiol , vol.167 , pp. 125-138
    • Smith, L.1    Watson, M.2    Gates, S.3
  • 38
    • 0026718685 scopus 로고
    • Alcohol-preferring rats have fewer dopamine D2 receptors in the limbic system
    • Stefanini E, Frau M, Garau MG et al. (1992) Alcohol-preferring rats have fewer dopamine D2 receptors in the limbic system. Alcohol Alcohol 27:127-30.
    • (1992) Alcohol Alcohol , vol.27 , pp. 127-130
    • Stefanini, E.1    Frau, M.2    Garau, M.G.3
  • 39
    • 2442665495 scopus 로고    scopus 로고
    • DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking
    • Thanos PK, Taintor NB, Rivera SN et al. (2004) DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking. Alcohol Clin Exp Res 28:720-8.
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 720-728
    • Thanos, P.K.1    Taintor, N.B.2    Rivera, S.N.3
  • 40
    • 0020636548 scopus 로고
    • Autoreceptors mediate the inhibition of dopamine synthesis by bromocriptine and lisuride in rats
    • Tissari AH, Rossetti ZL, Meloni M et al. (1983) Autoreceptors mediate the inhibition of dopamine synthesis by bromocriptine and lisuride in rats. Eur J Pharmacol 91:463-8.
    • (1983) Eur J Pharmacol , vol.91 , pp. 463-468
    • Tissari, A.H.1    Rossetti, Z.L.2    Meloni, M.3
  • 41
    • 84861459614 scopus 로고    scopus 로고
    • A DRD2 and ANKK1 haplotype is associated with nicotine dependence
    • doi: 10.1016/j.psychres.2011.1009.1024
    • Voisey J, Swagell CD, Hughes IP et al. (2012) A DRD2 and ANKK1 haplotype is associated with nicotine dependence. Psychiatry Res doi: 10.1016/j.psychres.2011.1009.1024.
    • (2012) Psychiatry Res
    • Voisey, J.1    Swagell, C.D.2    Hughes, I.P.3
  • 42
    • 0032832347 scopus 로고    scopus 로고
    • Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels
    • Volkow ND, Wang GJ, Fowler JS et al. (1999a) Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels. Am J Psychiatry 156:1440-3.
    • (1999) Am J Psychiatry , vol.156 , pp. 1440-1443
    • Volkow, N.D.1    Wang, G.J.2    Fowler, J.S.3
  • 43
    • 0032843942 scopus 로고    scopus 로고
    • Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors
    • Volkow ND, Wang GJ, Fowler JS et al. (1999b) Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors. J Pharmacol Exp Ther 291:409-15.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 409-415
    • Volkow, N.D.1    Wang, G.J.2    Fowler, J.S.3
  • 44
    • 33748288153 scopus 로고    scopus 로고
    • High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors
    • Volkow ND, Wang GJ, Begleiter H et al. (2006) High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors. Arch Gen Psychiatry 63:999-1008.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 999-1008
    • Volkow, N.D.1    Wang, G.J.2    Begleiter, H.3
  • 45
    • 4444330165 scopus 로고    scopus 로고
    • Advances in molecular genetics and the prevention and treatment of substance misuse: implications of association studies of the A1 allele of the D2 dopamine receptor gene
    • Young RM, Lawford BR, Nutting A et al. (2004) Advances in molecular genetics and the prevention and treatment of substance misuse: implications of association studies of the A1 allele of the D2 dopamine receptor gene. Addict Behav 29:1275-94.
    • (2004) Addict Behav , vol.29 , pp. 1275-1294
    • Young, R.M.1    Lawford, B.R.2    Nutting, A.3


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