Salivary interleukin-6 and-8 in patients with oral cancer and patients with chronic oral inflammatory diseases

Journal of Periodontology

Volumn 85, Issue 7, 2014, Pages 956-965

  Cheng, Yi Shing Lisa ^a   Jordan, Lee ^a   Gorugantula, Lakshmi Mitreyi ^b   Schneiderman, Emet ^a   Chen, Huey Shys ^c   Rees, Terry ^a  

^a BAYLOR COLLEGE OF DENTISTRY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF TOLEDO   (United States)

Author keywords

Chronic periodontitis; Interleukin 6; Interleukin 8; Lichen planus, oral; Mouth neoplasms; Saliva

Indexed keywords

BIOLOGICAL MARKER; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; INTERLEUKIN 6; INTERLEUKIN 8; SALIVA PROTEIN; TUMOR MARKER;

ADULT; AGED; CANCER STAGING; CHRONIC PERIODONTITIS; CLASSIFICATION; COMPARATIVE STUDY; FEMALE; HUMAN; IMMUNOLOGY; LICHEN PLANUS; MALE; MIDDLE AGED; MOUTH TUMOR; SALIVA; SQUAMOUS CELL CARCINOMA; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CARCINOMA, SQUAMOUS CELL; CHRONIC PERIODONTITIS; FEMALE; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LICHEN PLANUS, ORAL; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NEOPLASM STAGING; SALIVA; SALIVARY PROTEINS AND PEPTIDES; TUMOR MARKERS, BIOLOGICAL;

EID: 84904300051     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2013.130320     Document Type: Article

References (50)

1. Mankan AK, Lawless MW, Gray SG, Kelleher D, McManus R. NF-kappaB regulation: The nuclear response. J Cell Mol Med 2009;13:631-643.
2. Milward MR, Chapple IL, Wright HJ, Millard JL, Matthews JB, Cooper PR. Differential activation of NF-kappaB and gene expression in oral epithelial cells by periodontal pathogens. Clin Exp Immunol 2007; 148:307-324.
3. Duarte PM, de Oliveira MC, Tambeli CH, Parada CA, Casati MZ, Nociti FH Jr. Overexpression of interleukin-1b and interleukin-6 may play an important role in periodontal breakdown in type 2 diabetic patients. J Periodontal Res 2007;42:377-381.
4. Moutsopoulos NM, Madianos PN. Low-grade inflammation in chronic infectious diseases: Paradigm of periodontal infections. Ann N Y Acad Sci 2006;1088: 251-264.
5. Xu J, Wu HF, Ang ES, et al. NF-kappaB modulators in osteolytic bone diseases. Cytokine Growth Factor Rev 2009;20:7-17.
6. Feghali CA, Wright TM. Cytokines in acute and chronic inflammation. Front Biosci 1997;2:d12-d26.
7. Arellano-Garcia ME, Hu S, Wang J, et al. Multiplexed immunobead-based assay for detection of oral cancer protein biomarkers in saliva. Oral Dis 2008;14:705-712.
8. Katakura A, Kamiyama I, Takano N, et al. Comparison of salivary cytokine levels in oral cancer patients and healthy subjects. Bull Tokyo Dent Coll 2007;48:199-203.
9. Yang CY, Brooks E, Li Y, et al. Detection of picomolar levels of interleukin-8 in human saliva by SPR. Lab Chip 2005;5:1017-1023.
10. Rhodus NL, Ho V, Miller CS, Myers S, Ondrey F. NF-kappaB dependent cytokine levels in saliva of patients with oral preneoplastic lesions and oral squamous cell carcinoma. Cancer Detect Prev 2005;29:42-45.
11. St John MA, Li Y, Zhou X, et al. Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2004;130:929-935.
12. Zhang Y, Lin M, Zhang S, et al. NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: A study in an ethnic Chinese population. Cytokine 2008;41:144-149.
13. Rhodus NL, Cheng B, Myers S, Bowles W, Ho V, Ondrey F. A comparison of the pro-inflammatory, NF-kappaBdependent cytokines: TNF-alpha, IL-1-alpha, IL-6, and IL-8 in different oral fluids from oral lichen planus patients. Clin Immunol 2005;114:278-283.
14. Costa PP, Trevisan GL, Macedo GO, et al. Salivary interleukin-6, matrix metalloproteinase-8, and osteoprotegerin in patients with periodontitis and diabetes. J Periodontol 2010;81:384-391.
15. Prakasam S, Srinivasan M. Evaluation of salivary biomarker profiles following non-surgical management of chronic periodontitis. Oral Dis 2014;20:171-177.
16. Ebersole JL, Schuster JL, Stevens J, et al. Patterns of salivary analytes provide diagnostic capacity for distinguishing chronic adult periodontitis from health. J Clin Immunol 2013;33:271-279.
17. Teles RP, Likhari V, Socransky SS, Haffajee AD. Salivary cytokine levels in subjects with chronic periodontitis and in periodontally healthy individuals: Acrosssectional study. J Periodontal Res 2009;44:411-417.
18. Sexton WM, Lin Y, Kryscio RJ, Dawson DR, 3rd, Ebersole JL, Miller CS. Salivary biomarkers of periodontal disease in response to treatment. J Clin Periodontol 2011;38:434-441.
19. Albandar JM. Underestimation of periodontitis in NHANES surveys. J Periodontol 2011;82:337-341.
20. Burt B; Research, Science and Therapy Committee of the American Academy of Periodontology. Position paper: Epidemiology of periodontal diseases. J Periodontol 2005;76:1406-1419.
21. Eke PI, Dye BA, Wei L, Thornton-Evans GO, Genco RJ; CDC Periodontal Disease Surveillance workgroup. Prevalence of periodontitis in adults in the United States: 2009 and 2010. J Dent Res 2012;91:914-920.
22. Carrozzo M, Thorpe R. Oral lichen planus: A review. Minerva Stomatol 2009;58:519-537.
23. Neville BW, Damm DD, Allen CM, Bouquot JE. Lichen planus. In: Neville BW, Damm DD, Allen CM, Bouquot JE, eds. Oral and Maxillofacial Pathology, 3rd ed. St. Louis: Saunders Elsevier; 2009:782-788.
24. SahebJamee M, Eslami M, AtarbashiMoghadam F, Sarafnejad A. Salivary concentration of TNFalpha, IL1 alpha, IL6, and IL8 in oral squamous cell carcinoma. Med Oral Patol Oral Cir Bucal 2008;13:E292-E295.
25. Eke PI, Page RC, Wei L, Thornton-Evans G, Genco RJ. Update of the case definitions for population-based surveillance of periodontitis. J Periodontol 2012;83: 1449-1454.
26. Rhodus NL, Cheng B, Bowles W, Myers S, Miller L, Ondrey F. Proinflammatory cytokine levels in saliva before and after treatment of (erosive) oral lichen planus with dexamethasone. Oral Dis 2006;12:112-116.
27. Gorugantula LM, Rees T, Plemons J, Chen HS, Cheng YS. Salivary basic fibroblast growth factor in patients with oral squamous cell carcinoma or oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114:215-222.
28. Cheng YS, Rees T, Jordan L, et al. Salivary endothelin-1 potential for detecting oral cancer in patients with oral lichen planus or oral cancer in remission. Oral Oncol 2011;47:1122-1126.
29. Morse DE, Katz RV, Pendrys DG, et al. Smoking and drinking in relation to oral epithelial dysplasia. Cancer Epidemiol Biomarkers Prev 1996;5:769-777.
30. Dietrich T, Reichart PA, Scheifele C. Clinical risk factors of oral leukoplakia in a representative sample of the US population. Oral Oncol 2004;40:158-163.
31. Blot WJ, McLaughlin JK, Winn DM, et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 1988;48:3282-3287.
32. Mashberg A, Boffetta P, Winkelman R, Garfinkel L. Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans. Cancer 1993;72:1369-1375.
33. Lewin F, Norell SE, Johansson H, et al. Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: A population-based case-referent study in Sweden. Cancer 1998;82:1367-1375.
34. Faul F, Erdfelder E, Lang AG, Buchner A. G Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007;39:175-191.
35. Cohen J.Apower primer. Psychol Bull 1992;112:155-159.
36. Navazesh M. Methods for collecting saliva. Ann N Y Acad Sci 1993;694:72-77.
37. Thomas MV, Branscum A, Miller CS, Ebersole J, Al-Sabbagh M, Schuster JL. Within-subject variability in repeated measures of salivary analytes in healthy adults. J Periodontol 2009;80:1146-1153.
38. Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K. Current controversies in oral lichen planus: Report of an international consensus meeting. Part 2. Clinical management and malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;100:164-178.
39. van der Meij EH, Schepman KP, Smeele LE, van der Wal JE, Bezemer PD, van der Waal I. A review of the recent literature regarding malignant transformation of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;88:307-310.
40. Holmstrup P. The controversy of a premalignant potential of oral lichen planus is over. Oral Surg Oral Med Oral Pathol 1992;73:704-706.
41. Thongprasom K, Mutirangura A, Cheerat S. Telomerase activity in oral lichen planus. J Oral Pathol Med 1998;27:395-398.
42. Fujita H, Nagata M, Hoshina H, et al. Clinical significance and usefulness of quantification of telomerase activity in oral malignant and nonmalignant lesions. Int J Oral Maxillofac Surg 2004;33:693-699.
43. O'Flatharta C, Leader M, Kay E, et al. Telomerase activity detected in oral lichen planus by RNA in situ hybridisation: Not a marker for malignant transformation. J Clin Pathol 2002;55:602-607.
44. Femiano F, Scully C. DNA cytometry of oral leukoplakia and oral lichen planus. Med Oral Patol Oral Cir Bucal 2005;10(Suppl. 1):E9-E14.
45. KimJ, Yook JI, Lee EH, et al. Evaluation of premalignant potential in oral lichen planus using interphase cytogenetics. J Oral Pathol Med 2001;30:65-72.
46. Acay RR, Felizzola CR, de Araújo N, de Sousa SO. Evaluation of proliferative potential in oral lichen planus and oral lichenoid lesions using immunohistochemical expression of p53 and Ki67. Oral Oncol 2006; 42:475-480.
47. Ji S, Choi Y. Innate immune response to oral bacteria and the immune evasive characteristics of periodontal pathogens. J Periodontal Implant Sci 2013;43:3-11.
48. Scully C, Carrozzo M. Oral mucosal disease: Lichen planus. Br J Oral Maxillofac Surg 2008;46:15-21.
49. Hu Z, Zimmermann BG, Zhou H, et al. Exon-level expression profiling: A comprehensive transcriptome analysis of oral fluids. Clin Chem 2008;54:824-832.
50. Brinkmann O, Kastratovic DA, Dimitrijevic MV, et al. Oral squamous cell carcinoma detection by salivary biomarkers in a Serbian population. Oral Oncol 2011; 47:51-55.