Evaluation of proliferative potential in oral lichen planus and oral lichenoid lesions using immunohistochemical expression of p53 and Ki67

Oral Oncology

Volumn 42, Issue 5, 2006, Pages 475-480

  Acay, Renata Rodrigues ^a   Felizzola, Claudia Ronca ^a   Soares de Araújo, Ney ^a   Machado de Sousa, Suzana Orsini ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Immunohistochemistry; Ki67; Oral lichen planus; Oral lichenoid lesions; p53; Premalignancy

Indexed keywords

BIOTIN; KI 67 ANTIGEN; PROTEIN P53; STREPTAVIDIN;

ANTIGEN EXPRESSION; ARTICLE; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST; DYSPLASIA; EVALUATION; HUMAN; IMMUNOHISTOCHEMISTRY; LICHEN PLANUS; LICHENOID; MALIGNANT TRANSFORMATION; MOUTH CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; STATISTICAL SIGNIFICANCE;

CELL PROLIFERATION; DISEASE PROGRESSION; HUMANS; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; LICHEN PLANUS, ORAL; LICHENOID ERUPTIONS; MOUTH NEOPLASMS; PRECANCEROUS CONDITIONS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33646143537     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2005.09.012     Document Type: Article

References (25)

1. Abbey L.M., Kaugars G.E., Gunsolley J.C., et al. Intraexaminer and interexaminer reliability in diagnosis of oral epithelial dysplasia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 80 2 (1995) 188-191
2. Axell T., and Rundquist L. Oral lichen planus-a demographic study. Commun Dent Oral Epidemiol 15 1 (1987) 52-56
3. Campisi G., Giovanelli L., Aricò P., Lama A., Di Liberto C., Ammatuna P., et al. HPV DNA in clinically different variants of oral leucoplakia and lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98 6 (2004) 705-711
4. Gerdes J., Schwab U., Lemke H., and Stein H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31 1 (1983) 13-20
5. Gomes A.P.N., Araújo V.C., and Pinto Jr. D.S. Avaliação imuno-histoquímica de p53 e PCNA como marcadores de risco para lesões bucais potencialmente malignas. RPG Rev Pós Grad 7 4 (2000) 349-355
6. Hallopeau H. Sur un cas de lichen de Wilson gingival avec neoplasie voisine dans la region maxillaire. Bull Soc Fr Dermatol Syphiligr 17 (1910) 32
7. Ha P.K., Pai S.I., Westra W.H., Gillison M.L., Tong B.C., Sidransky D., et al. Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res 8 5 (2002) 1203-1209
8. Hirota M., Ito T., Okudela K., et al. Cell proliferation activity and the expression of the cell cycle regulatory proteins in oral lichen planus. J Oral Pathol Med 31 4 (2002) 204-212
9. Karabulut A., Reibel J., Therkildsen M.H., Praetorius F., Nielsen H.W., and Dabelsteen E. Observer variability in the histologic assessment of oral premalignant lesions. J Pathol Med 24 5 (1995) 198-200
10. Krutchkoff D.J., and Eisenberg E. Lichenoid dysplasia: a distinct histopathologic entity. Oral Surg Oral Med Oral Pathol 60 1 (1985) 308-315
11. Laprie C., Abadie J., Amardeilh M.F., Net J.L., Lagadic M., and Delverdier M. MIB-1 immunoreactivity correlates with biological behaviour in canine cutaneous melanoma. Vet Dermatol 12 3 (2001) 139-147
12. Lo Muzio L., D'Angelo M., Procaccini M., Bambini F., Calvino F., Florena A.M., et al. Expression of cell cycle markers and human papilloma virus infection in oral squamous cell carcinoma: use of fuzzy neural networks. Int J Cancer 115 5 (2005) 717-723
13. Mignogna M.D., Lo Russo L., Fedele S., Ruoppo E., Califano L., and Lo Muzio L. Clinical behaviour of malignant transforming oral lichen planus. EJSO 28 8 (2002) 838-843
14. Min B.M., Baek J.H., Shin K.H., Gujuluva C.N., Cherrick H.M., and Park N.H. Inactivation of the p53 gene by either mutation or HPV infection is extremely frequent in human oral squamous cell carcinoma cell lines. Eur J Cancer B Oral Oncol 30B 5 (1994) 338-345
15. Ostwald C., Rutsatz K., Schweder J., Schmidt W., Gundlach K., and Barten M. Human papillomavirus 6/11, 16 and 18 in oral carcinomas and benign oral lesions. Med Microbiol Immunol (Berl) 192 3 (2003) 145-148
16. Piatelli A., Rubini C., Fioroni M., Iezzi G., and Santinelli A. Prevalence of p53, bcl-2, and Ki67 immunoreactivity and of apoptosis in normal oral epithelium and in premalignant and malignant lesions of the oral cavity. J Oral Maxillofac Surg 60 5 (2002) 532-540
17. Pindborg J.J., Reibel J., and Holmstrup P. Subjectivity in evaluating oral epithelial dysplasia, carcinoma in situ and initial carcinoma. J Oral Pathol 14 9 (1985) 698-708
18. Schepman K.P., and van der Waal I. A proposal for a classification and staging system for oral leucoplakia: a preliminary study. Eur J Cancer B Oral Oncol 31B 6 (1995) 396-398
19. Schifter M., Jones A.M., and Walker D.M. Epithelial p53 gene expression and mutational analysis, combined with growth fraction assessment, in oral lichen planus. J Oral Pathol Med 27 7 (1998) 318-324
20. Schluter C., Duchrow M., Wohlenberg C., et al. The cell proliferation-associated antigen of antibody Ki67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J Cell Biol 123 3 (1993) 513-522
21. Scully C., and el-Kom M. Lichen planus-review and update on pathogenesis. J Oral Pathol 14 6 (1985) 431-458
22. Taniguchi Y., Nagao T., Maeda H., Kameyama Y., and Warnakulasuriya K.A.A.S. Epithelial cell proliferation in oral lichen planus. Cell Prolif 35 Suppl. 1 (2002) 103-109
23. van der Meij E.H., Schepman K.P., and van der Waal I. The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96 2 (2003) 164-171
24. Valente G., Pagano M., Carrozzo M., et al. Sequential immunohistochemical p53 expression in biopsies of oral lichen planus undergoing malignant evolution. J Oral Pathol Med 30 3 (2001) 135-140
25. Werness B.A., Levine A.J., and Howley P.M. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 248 4951 (1990) 76-79