-
1
-
-
84943235131
-
SH2 domain-containing protein tyrosine phosphatases
-
In Bradshaw RA, Dennis EA (ed), 2nd ed, Elsevier, San Diego, CA
-
Neel BG, Guo H, Pao L. 2009. SH2 domain-containing protein tyrosine phosphatases, p 707-728. In Bradshaw RA, Dennis EA (ed), Handbook in cell signaling, 2nd ed, vol 2. Elsevier, San Diego, CA.
-
(2009)
Handbook in cell signaling
, vol.2
, pp. 707-728
-
-
Neel, B.G.1
Guo, H.2
Pao, L.3
-
2
-
-
0032548830
-
Crystal structure of the tyrosine phosphatase SHP-2
-
Hof P, Pluskey S, Dhe-Pagganon S, Eck MJ, Shoelson SE. 1998. Crystal structure of the tyrosine phosphatase SHP-2. Cell 92:441-450. http://dx .doi.org/10.1016/S0092-8674(00)80938-1.
-
(1998)
Cell
, vol.92
, pp. 441-450
-
-
Hof, P.1
Pluskey, S.2
Dhe-Pagganon, S.3
Eck, M.J.4
Shoelson, S.E.5
-
3
-
-
13844265841
-
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations
-
Mohi MG, Williams IR, Dearolf CR, Chan G, Kutok JL, Cohen S, Morgan K, Boulton C, Shigematsu H, Keilhack H, Akashi K, Gilliland DG, Neel BG. 2005. Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations. Cancer Cell 7:179-191. http://dx.doi.org/10.1016/j.ccr.2005.01.010.
-
(2005)
Cancer Cell
, vol.7
, pp. 179-191
-
-
Mohi, M.G.1
Williams, I.R.2
Dearolf, C.R.3
Chan, G.4
Kutok, J.L.5
Cohen, S.6
Morgan, K.7
Boulton, C.8
Shigematsu, H.9
Keilhack, H.10
Akashi, K.11
Gilliland, D.G.12
Neel, B.G.13
-
4
-
-
33846945811
-
Protein tyrosine phosphatase function: the substrate perspective
-
Tiganis T, Bennett AM. 2007. Protein tyrosine phosphatase function: the substrate perspective. Biochem. J. 402:1-15. http://dx.doi.org/10.1042/BJ20061548.
-
(2007)
Biochem. J.
, vol.402
, pp. 1-15
-
-
Tiganis, T.1
Bennett, A.M.2
-
5
-
-
0030921502
-
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2
-
Saxton TM, Henkemeyer M, Gasca S, Shen R, Rossi DJ, Shalaby F, Feng GS, Pawson T. 1997. Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2. EMBO J. 16:2352-2364. http://dx.doi.org/10.1093/emboj/16.9.2352.
-
(1997)
EMBO J.
, vol.16
, pp. 2352-2364
-
-
Saxton, T.M.1
Henkemeyer, M.2
Gasca, S.3
Shen, R.4
Rossi, D.J.5
Shalaby, F.6
Feng, G.S.7
Pawson, T.8
-
6
-
-
33644547703
-
A Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival
-
Yang W, Klaman LD, Chen B, Araki T, Harada H, Thomas SM, George EL, Neel BG. 2006. A Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival. Dev. Cell 10:317-327. http://dx.doi.org/10 .1016/j.devcel.2006.01.002.
-
(2006)
Dev. Cell
, vol.10
, pp. 317-327
-
-
Yang, W.1
Klaman, L.D.2
Chen, B.3
Araki, T.4
Harada, H.5
Thomas, S.M.6
George, E.L.7
Neel, B.G.8
-
7
-
-
0026630991
-
corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso
-
Perkins LA, Larsen I, Perrimon N. 1992. corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell 70:225-236. http://dx .doi.org/10.1016/0092-8674(92)90098-W.
-
(1992)
Cell
, vol.70
, pp. 225-236
-
-
Perkins, L.A.1
Larsen, I.2
Perrimon, N.3
-
8
-
-
0038771965
-
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
-
Neel BG, Gu H, Pao L. 2003. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem. Sci. 28:284-293. http://dx.doi.org/10.1016/S0968-0004(03)00091-4.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 284-293
-
-
Neel, B.G.1
Gu, H.2
Pao, L.3
-
9
-
-
18344385476
-
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
-
Tartaglia M, Mehler EL, Goldberg R, Zampino G, Brunner HG, Kremer H, van der Burgt I, Crosby AH, Ion A, Jeffery S, Kalidas K, Patton MA, Kucherlapati RS, Gelb BD. 2001. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat. Genet. 29:465-468. http://dx.doi.org/10.1038/ng772.
-
(2001)
Nat. Genet.
, vol.29
, pp. 465-468
-
-
Tartaglia, M.1
Mehler, E.L.2
Goldberg, R.3
Zampino, G.4
Brunner, H.G.5
Kremer, H.6
van der Burgt, I.7
Crosby, A.H.8
Ion, A.9
Jeffery, S.10
Kalidas, K.11
Patton, M.A.12
Kucherlapati, R.S.13
Gelb, B.D.14
-
10
-
-
18444401014
-
Noonan syndrome and related disorders: genetics and pathogenesis
-
Tartaglia M, Gelb BD. 2005. Noonan syndrome and related disorders: genetics and pathogenesis. Annu. Rev. Genomics Hum. Genet. 6:45-68. http://dx.doi.org/10.1146/annurev.genom.6.080604.162305.
-
(2005)
Annu. Rev. Genomics Hum. Genet.
, vol.6
, pp. 45-68
-
-
Tartaglia, M.1
Gelb, B.D.2
-
11
-
-
37749041167
-
Shp2 knockdown and Noonan/LEOPARD mutant Shp2-induced gastrulation defects
-
Jopling C, van Geemen D, den Hertog J. 2007. Shp2 knockdown and Noonan/LEOPARD mutant Shp2-induced gastrulation defects. PLoS Genet. 3:e225. http://dx.doi.org/10.1371/journal.pgen.0030225.
-
(2007)
PLoS Genet.
, vol.3
-
-
Jopling, C.1
van Geemen, D.2
den Hertog, J.3
-
12
-
-
79956111812
-
Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects
-
Runtuwene V, van Eekelen M, Overvoorde J, Rehmann H, Yntema HG, Nillesen WM, van Haeringen A, van der Burgt I, Burgering B, den Hertog J. 2011. Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects. Dis. Model Mech. 4:393-399. http://dx.doi.org/10.1242/dmm.007112.
-
(2011)
Dis. Model Mech.
, vol.4
, pp. 393-399
-
-
Runtuwene, V.1
van Eekelen, M.2
Overvoorde, J.3
Rehmann, H.4
Yntema, H.G.5
Nillesen, W.M.6
van Haeringen, A.7
van der Burgt, I.8
Burgering, B.9
den Hertog, J.10
-
13
-
-
58149395502
-
Noonan, Costello and cardio-faciocutaneous syndromes: dysregulation of the Ras-MAPK pathway
-
Tidyman WE, Rauen KA. 2008. Noonan, Costello and cardio-faciocutaneous syndromes: dysregulation of the Ras-MAPK pathway. Expert Rev. Mol. Med. 10:e37. http://dx.doi.org/10.1017/S1462399408000902.
-
(2008)
Expert Rev. Mol. Med.
, vol.10
-
-
Tidyman, W.E.1
Rauen, K.A.2
-
14
-
-
79952225388
-
RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it
-
Gelb BD, Tartaglia M. 2011. RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it. J. Clin. Invest. 121:844-847. http://dx.doi.org/10.1172/JCI46399.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 844-847
-
-
Gelb, B.D.1
Tartaglia, M.2
-
15
-
-
33646096207
-
PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects
-
Kontaridis MI, Swanson KD, David FS, Barford D, Neel BG. 2006. PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects. J. Biol. Chem. 281:6785-6792. http://dx.doi .org/10.1074/jbc.M513068200.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 6785-6792
-
-
Kontaridis, M.I.1
Swanson, K.D.2
David, F.S.3
Barford, D.4
Neel, B.G.5
-
16
-
-
31544452561
-
Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease
-
Tartaglia M, Martinelli S, Stella L, Bocchinfuso G, Flex E, Cordeddu V, Zampino G, Burgt IV, Palleschi A, Petrucci TC, Sorcini M, Schoch C, Foa R, Emanuel PD, Gelb BD. 2006. Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease. Am. J. Hum. Genet. 78:279-290. http://dx.doi.org/10.1086/499925.
-
(2006)
Am. J. Hum. Genet.
, vol.78
, pp. 279-290
-
-
Tartaglia, M.1
Martinelli, S.2
Stella, L.3
Bocchinfuso, G.4
Flex, E.5
Cordeddu, V.6
Zampino, G.7
Burgt, I.V.8
Palleschi, A.9
Petrucci, T.C.10
Sorcini, M.11
Schoch, C.12
Foa, R.13
Emanuel, P.D.14
Gelb, B.D.15
-
17
-
-
33646117025
-
Reduced phosphatase activity of SHP-2 in LEOPARD syndrome: consequences for PI3K binding on Gab1
-
Hanna N, Montagner A, Lee WH, Miteva M, Vidal M, Vidaud M, Parfait B, Raynal P. 2006. Reduced phosphatase activity of SHP-2 in LEOPARD syndrome: consequences for PI3K binding on Gab1. FEBS Lett. 580:2477-2482. http://dx.doi.org/10.1016/j.febslet.2006.03.088.
-
(2006)
FEBS Lett.
, vol.580
, pp. 2477-2482
-
-
Hanna, N.1
Montagner, A.2
Lee, W.H.3
Miteva, M.4
Vidal, M.5
Vidaud, M.6
Parfait, B.7
Raynal, P.8
-
18
-
-
33749003166
-
Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction
-
Gelb BD, Tartaglia M. 2006. Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction. Hum. Mol. Genet. 15(Suppl 2):R220-R226. http://dx.doi.org/10.1093/hmg/ddl197.
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.SUPPL. 2
-
-
Gelb, B.D.1
Tartaglia, M.2
-
19
-
-
84876273572
-
Structural and mechanistic insights into LEOPARD syndrome-associated SHP2 mutations
-
Yu ZH, Xu J, Walls CD, Chen L, Zhang S, Zhang R, Wu L, Wang L, Liu S, Zhang ZY. 2013. Structural and mechanistic insights into LEOPARD syndrome-associated SHP2 mutations. J. Biol. Chem. 288:10472-10482. http://dx.doi.org/10.1074/jbc.M113.450023.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 10472-10482
-
-
Yu, Z.H.1
Xu, J.2
Walls, C.D.3
Chen, L.4
Zhang, S.5
Zhang, R.6
Wu, L.7
Wang, L.8
Liu, S.9
Zhang, Z.Y.10
-
20
-
-
84899062331
-
Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11)
-
Qiu W, Wang X, Romanov V, Hutchinson A, Lin A, Ruzanov M, Battaile KP, Pai EF, Neel BG, Chirgadze NY. 2014. Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11). BMC Struct. Biol. 14:10. http://dx.doi.org/10.1186/1472-6807-14-10.
-
(2014)
BMC Struct. Biol.
, vol.14
, pp. 10
-
-
Qiu, W.1
Wang, X.2
Romanov, V.3
Hutchinson, A.4
Lin, A.5
Ruzanov, M.6
Battaile, K.P.7
Pai, E.F.8
Neel, B.G.9
Chirgadze, N.Y.10
-
21
-
-
0034052841
-
Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosinebased inhibitory motifs
-
Zhao R, Zhao ZJ. 2000. Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosinebased inhibitory motifs. J. Biol. Chem. 275:5453-5459. http://dx.doi.org/10.1074/jbc.275.8.5453.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5453-5459
-
-
Zhao, R.1
Zhao, Z.J.2
-
22
-
-
0037453249
-
Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs
-
Zhao R, Zhao ZJ. 2003. Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs. Biochem. Biophys. Res. Commun. 303:1028 -1033. http://dx.doi.org/10.1016/S0006-291X(03)00484-4.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.303
-
-
Zhao, R.1
Zhao, Z.J.2
-
23
-
-
15444348895
-
Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2
-
Zhao ZJ, Zhao R. 1998. Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2. J. Biol. Chem. 273:29367-29372. http://dx.doi.org/10.1074/jbc .273.45.29367.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29367-29372
-
-
Zhao, Z.J.1
Zhao, R.2
-
24
-
-
35648959797
-
The murine ortholog of the SHP-2 binding molecule, PZR accelerates cell migration on fibronectin and is expressed in early embryo formation
-
Roubelakis MG, Martin-Rendon E, Tsaknakis G, Stavropoulos A, Watt SM. 2007. The murine ortholog of the SHP-2 binding molecule, PZR accelerates cell migration on fibronectin and is expressed in early embryo formation. J. Cell. Biochem. 102:955-969. http://dx.doi.org/10.1002/jcb .21334.
-
(2007)
J. Cell. Biochem.
, vol.102
, pp. 955-969
-
-
Roubelakis, M.G.1
Martin-Rendon, E.2
Tsaknakis, G.3
Stavropoulos, A.4
Watt, S.M.5
-
25
-
-
47249118481
-
Noonan syndrome-associated SHP-2/ PTPN11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated Erk activation
-
Eminaga S, Bennett AM. 2008. Noonan syndrome-associated SHP-2/ PTPN11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated Erk activation. J. Biol. Chem. 283: 15328-15338. http://dx.doi.org/10.1074/jbc.M801382200.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15328-15338
-
-
Eminaga, S.1
Bennett, A.M.2
-
27
-
-
0037561996
-
Redox-regulated rotational coupling of receptor protein-tyrosine phosphatase alpha dimers
-
van der Wijk T, Blanchetot C, Overvoorde J, den Hertog J. 2003. Redox-regulated rotational coupling of receptor protein-tyrosine phosphatase alpha dimers. J. Biol. Chem. 278:13968-13974. http://dx.doi.org/10.1074/jbc.M300632200.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13968-13974
-
-
van der Wijk, T.1
Blanchetot, C.2
Overvoorde, J.3
den Hertog, J.4
-
28
-
-
2942589265
-
SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway
-
Kontaridis MI, Eminaga S, Fornaro M, Zito CI, Sordella R, Settleman J, Bennett AM. 2004. SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Mol. Cell. Biol. 24:5340-5352. http://dx.doi.org/10.1128/MCB.24.12.5340-5352.2004.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5340-5352
-
-
Kontaridis, M.I.1
Eminaga, S.2
Fornaro, M.3
Zito, C.I.4
Sordella, R.5
Settleman, J.6
Bennett, A.M.7
-
29
-
-
33749577870
-
SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth
-
Fornaro M, Burch PM, Yang W, Zhang L, Hamilton CE, Kim JH, Neel BG, Bennett AM. 2006. SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth. J. Cell Biol. 175:87-97. http://dx.doi.org/10.1083/jcb.200602029.
-
(2006)
J. Cell Biol.
, vol.175
, pp. 87-97
-
-
Fornaro, M.1
Burch, P.M.2
Yang, W.3
Zhang, L.4
Hamilton, C.E.5
Kim, J.H.6
Neel, B.G.7
Bennett, A.M.8
-
30
-
-
4043056497
-
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation
-
Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG. 2004. Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation. Nat. Med. 10:849-857. http://dx.doi.org/10.1038/nm1084.
-
(2004)
Nat. Med.
, vol.10
, pp. 849-857
-
-
Araki, T.1
Mohi, M.G.2
Ismat, F.A.3
Bronson, R.T.4
Williams, I.R.5
Kutok, J.L.6
Yang, W.7
Pao, L.I.8
Gilliland, D.G.9
Epstein, J.A.10
Neel, B.G.11
-
32
-
-
0027453569
-
Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos
-
Thisse C, Thisse B, Schilling TF, Postlethwait JH. 1993. Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos. Development 119:1203-1215.
-
(1993)
Development
, vol.119
, pp. 1203-1215
-
-
Thisse, C.1
Thisse, B.2
Schilling, T.F.3
Postlethwait, J.H.4
-
33
-
-
77951205715
-
RPTPalpha and PTPepsilon signaling via Fyn/Yes and RhoA is essential for zebrafish convergence and extension cell movements during gastrulation
-
van Eekelen M, Runtuwene V, Overvoorde J, den Hertog J. 2010. RPTPalpha and PTPepsilon signaling via Fyn/Yes and RhoA is essential for zebrafish convergence and extension cell movements during gastrulation. Dev. Biol. 340:626-639. http://dx.doi.org/10.1016/j.ydbio.2010.02.026.
-
(2010)
Dev. Biol.
, vol.340
, pp. 626-639
-
-
van Eekelen, M.1
Runtuwene, V.2
Overvoorde, J.3
den Hertog, J.4
-
34
-
-
36849065315
-
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
-
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ. 2007. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 131:1190-1203. http://dx.doi.org/10 .1016/j.cell.2007.11.025.
-
(2007)
Cell
, vol.131
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
Possemato, A.4
Yu, J.5
Haack, H.6
Nardone, J.7
Lee, K.8
Reeves, C.9
Li, Y.10
Hu, Y.11
Tan, Z.12
Stokes, M.13
Sullivan, L.14
Mitchell, J.15
Wetzel, R.16
Macneill, J.17
Ren, J.M.18
Yuan, J.19
Bakalarski, C.E.20
Villen, J.21
Kornhauser, J.M.22
Smith, B.23
Li, D.24
Zhou, X.25
Gygi, S.P.26
Gu, T.L.27
Polakiewicz, R.D.28
Rush, J.29
Comb, M.J.30
more..
-
35
-
-
38649119730
-
Signaling networks assembled by oncogenic EGFR and c-Met
-
Guo A, Villén J, Kornhauser J, Lee KA, Stokes MP, Rikova K, Possemato A, Nardone J, Innocenti G, Wetzel R, Wang Y, MacNeill J, Mitchell J, Gygi SP, Rush J, Polakiewicz RD, Comb MJ. 2008. Signaling networks assembled by oncogenic EGFR and c-Met. Proc. Natl. Acad. Sci. U. S. A. 105:692-697. http://dx.doi.org/10.1073/pnas.0707270105.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 692-697
-
-
Guo, A.1
Villén, J.2
Kornhauser, J.3
Lee, K.A.4
Stokes, M.P.5
Rikova, K.6
Possemato, A.7
Nardone, J.8
Innocenti, G.9
Wetzel, R.10
Wang, Y.11
MacNeill, J.12
Mitchell, J.13
Gygi, S.P.14
Rush, J.15
Polakiewicz, R.D.16
Comb, M.J.17
-
36
-
-
21144458164
-
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
-
Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ. 2005. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Nat. Biotechnol. 23:94-101. http://dx.doi .org/10.1038/nbt1046.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 94-101
-
-
Rush, J.1
Moritz, A.2
Lee, K.A.3
Guo, A.4
Goss, V.L.5
Spek, E.J.6
Zhang, H.7
Zha, X.M.8
Polakiewicz, R.D.9
Comb, M.J.10
-
37
-
-
84861161220
-
PTMScan direct: identification and quantification of peptides from critical signaling proteins by immunoaffinity enrichment coupled with LC-MS/MS
-
Stokes MP, Farnsworth CL, Moritz A, Silva JC, Jia X, Lee KA, Guo A, Polakiewicz RD, Comb MJ. 2012. PTMScan direct: identification and quantification of peptides from critical signaling proteins by immunoaffinity enrichment coupled with LC-MS/MS. Mol. Cell. Proteomics 11: 187-201. http://dx.doi.org/10.1074/mcp.M111.015883.
-
(2012)
Mol. Cell. Proteomics
, vol.11
, pp. 187-201
-
-
Stokes, M.P.1
Farnsworth, C.L.2
Moritz, A.3
Silva, J.C.4
Jia, X.5
Lee, K.A.6
Guo, A.7
Polakiewicz, R.D.8
Comb, M.J.9
-
38
-
-
33749853607
-
A probabilitybased approach for high-throughput protein phosphorylation analysis and site localization
-
Beausoleil SA, Villen J, Gerber SA, Rush J, Gygi SP. 2006. A probabilitybased approach for high-throughput protein phosphorylation analysis and site localization. Nat. Biotechnol. 24:1285-1292. http://dx.doi.org/10 .1038/nbt1240.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1285-1292
-
-
Beausoleil, S.A.1
Villen, J.2
Gerber, S.A.3
Rush, J.4
Gygi, S.P.5
-
39
-
-
33847630405
-
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
-
Elias JE, Gygi SP. 2007. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat. Methods 4:207-214. http://dx.doi.org/10.1038/nmeth1019.
-
(2007)
Nat. Methods
, vol.4
, pp. 207-214
-
-
Elias, J.E.1
Gygi, S.P.2
-
40
-
-
78650466243
-
A tissue-specific atlas of mouse protein phosphorylation and expression
-
Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP. 2010. A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143:1174-1189. http://dx.doi.org/10.1016/j.cell.2010.12.001.
-
(2010)
Cell
, vol.143
, pp. 1174-1189
-
-
Huttlin, E.L.1
Jedrychowski, M.P.2
Elias, J.E.3
Goswami, T.4
Rad, R.5
Beausoleil, S.A.6
Villen, J.7
Haas, W.8
Sowa, M.E.9
Gygi, S.P.10
-
41
-
-
0029644596
-
Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database
-
Yates JR, III, Eng JK, McCormack AL, Schieltz D. 1995. Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database. Anal. Chem. 67:1426-1436. http://dx.doi .org/10.1021/ac00104a020.
-
(1995)
Anal. Chem.
, vol.67
, pp. 1426-1436
-
-
Yates III, J.R.1
Eng, J.K.2
McCormack, A.L.3
Schieltz, D.4
-
42
-
-
20044370091
-
Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements
-
Jopling C, den Hertog J. 2005. Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements. EMBO Rep. 6:426-431. http://dx.doi.org/10.1038/sj.embor.7400386.
-
(2005)
EMBO Rep.
, vol.6
, pp. 426-431
-
-
Jopling, C.1
den Hertog, J.2
-
43
-
-
34249680274
-
p53 activation by knockdown technologies
-
Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. 2007. p53 activation by knockdown technologies. PLoS Genet. 3:e78. http://dx.doi.org/10.1371/journal.pgen.0030078.
-
(2007)
PLoS Genet.
, vol.3
-
-
Robu, M.E.1
Larson, J.D.2
Nasevicius, A.3
Beiraghi, S.4
Brenner, C.5
Farber, S.A.6
Ekker, S.C.7
-
44
-
-
77952943391
-
Phosphatase-dependent and-independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis
-
Stewart RA, Sanda T, Widlund HR, Zhu S, Swanson KD, Hurley AD, Bentires-Alj M, Fisher DE, Kontaridis MI, Look AT, Neel BG. 2010. Phosphatase-dependent and-independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis. Dev. Cell 18:750-762. http://dx.doi.org/10.1016/j.devcel.2010.03.009.
-
(2010)
Dev. Cell
, vol.18
, pp. 750-762
-
-
Stewart, R.A.1
Sanda, T.2
Widlund, H.R.3
Zhu, S.4
Swanson, K.D.5
Hurley, A.D.6
Bentires-Alj, M.7
Fisher, D.E.8
Kontaridis, M.I.9
Look, A.T.10
Neel, B.G.11
-
45
-
-
0037040904
-
Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling
-
Zhao R, Guerrah A, Tang H, Zhao ZJ. 2002. Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling. J. Biol. Chem. 277:7882-7888. http://dx.doi.org/10.1074/jbc.M111914200.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7882-7888
-
-
Zhao, R.1
Guerrah, A.2
Tang, H.3
Zhao, Z.J.4
-
46
-
-
79952235006
-
Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation
-
Marin TM, Keith K, Davies B, Conner DA, Guha P, Kalaitzidis D, Wu X, Lauriol J, Wang B, Bauer M, Bronson R, Franchini KG, Neel BG, Kontaridis MI. 2011. Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation. J. Clin. Invest. 121:1026-1043. http://dx.doi.org/10.1172/JCI44972.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1026-1043
-
-
Marin, T.M.1
Keith, K.2
Davies, B.3
Conner, D.A.4
Guha, P.5
Kalaitzidis, D.6
Wu, X.7
Lauriol, J.8
Wang, B.9
Bauer, M.10
Bronson, R.11
Franchini, K.G.12
Neel, B.G.13
Kontaridis, M.I.14
-
47
-
-
45949088286
-
Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells
-
Kusano K, Thomas TN, Fujiwara K. 2008. Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells. Endothelium 15:127-136. http://dx.doi.org/10.1080/10623320802125250.
-
(2008)
Endothelium
, vol.15
, pp. 127-136
-
-
Kusano, K.1
Thomas, T.N.2
Fujiwara, K.3
-
49
-
-
0037335855
-
Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration
-
Zannettino AC, Roubelakis M, Welldon KJ, Jackson DE, Simmons PJ, Bendall LJ, Henniker A, Harrison KL, Niutta S, Bradstock KF, Watt SM. 2003. Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration. Biochem. J. 370:537-549. http://dx.doi.org/10 .1042/BJ20020935.
-
(2003)
Biochem. J.
, vol.370
, pp. 537-549
-
-
Zannettino, A.C.1
Roubelakis, M.2
Welldon, K.J.3
Jackson, D.E.4
Simmons, P.J.5
Bendall, L.J.6
Henniker, A.7
Harrison, K.L.8
Niutta, S.9
Bradstock, K.F.10
Watt, S.M.11
-
50
-
-
33847046390
-
Structural and functional effects of disease-causing amino acid substitutions affecting residues Ala72 and Glu76 of the protein tyrosine phosphatase SHP-2
-
Bocchinfuso G, Stella L, Martinelli S, Flex E, Carta C, Pantaleoni F, Pispisa B, Venanzi M, Tartaglia M, Palleschi A. 2007. Structural and functional effects of disease-causing amino acid substitutions affecting residues Ala72 and Glu76 of the protein tyrosine phosphatase SHP-2. Proteins 66:963-974. http://dx.doi.org/10.1002/prot.21050.
-
(2007)
Proteins
, vol.66
, pp. 963-974
-
-
Bocchinfuso, G.1
Stella, L.2
Martinelli, S.3
Flex, E.4
Carta, C.5
Pantaleoni, F.6
Pispisa, B.7
Venanzi, M.8
Tartaglia, M.9
Palleschi, A.10
-
51
-
-
0033580431
-
The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism
-
Walter AO, Peng ZY, Cartwright CA. 1999. The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism. Oncogene 18:1911-1920. http://dx.doi.org/10.1038/sj.onc.1202513.
-
(1999)
Oncogene
, vol.18
, pp. 1911-1920
-
-
Walter, A.O.1
Peng, Z.Y.2
Cartwright, C.A.3
-
52
-
-
0028837693
-
Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association
-
Peng Z-Y, Cartwright CA. 1995. Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association. Oncogene 11:1955-1962.
-
(1995)
Oncogene
, vol.11
, pp. 1955-1962
-
-
Peng, Z.-Y.1
Cartwright, C.A.2
-
53
-
-
10744223870
-
Shp2 regulates SRC family kinase activity and ras/erk activation by controlling csk recruitment
-
Zhang SQ, Yang W, Kontaridis MI, Bivona TG, Wen G, Araki T, Luo J, Thompson JA, Schraven BL, Philips MR, Neel BG. 2004. Shp2 regulates SRC family kinase activity and ras/erk activation by controlling csk recruitment. Mol. Cell 13:341-355. http://dx.doi.org/10.1016/S1097-2765(04)00050-4.
-
(2004)
Mol. Cell
, vol.13
, pp. 341-355
-
-
Zhang, S.Q.1
Yang, W.2
Kontaridis, M.I.3
Bivona, T.G.4
Wen, G.5
Araki, T.6
Luo, J.7
Thompson, J.A.8
Schraven, B.L.9
Philips, M.R.10
Neel, B.G.11
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