Pancreatic insulin-producing cells differentiated from human embryonic stem cells correct hyperglycemia in SCID/NOD mice, an animal model of diabetes

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Hua, Xiu Feng ^a   Wang, Yan Wei ^a   Tang, Yu Xiao ^a   Yu, Sheng Qiang ^a   Jin, Shao Hua ^a   Meng, Xiao Mei ^a   Li, Hua Feng ^a   Liu, Fu Jun ^a   Sun, Qiang ^b   Wang, Hai Yan ^a   Li, Jian Yuan ^a  

^a YANTAI YUHUANGDING HOSPITAL   (China)

^b Chinese People's Liberation Army Hospital 107   (China)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLUCAGON; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; TRANSCRIPTION FACTOR PDX 1; GLUCOSE BLOOD LEVEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CLINICAL PROTOCOL; CONTROLLED STUDY; DIABETES MELLITUS; EMBRYONIC STEM CELL; EPIDIDYMIS FAT; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; GRAFT SURVIVAL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PROTEIN SECRETION; SCID MOUSE; ANIMAL; BLOOD; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODEL; PANCREAS; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PATHOLOGY; SECRETION (PROCESS); TRANSPLANTATION;

ANIMALS; BLOOD GLUCOSE; C-PEPTIDE; CELL DIFFERENTIATION; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED NOD; PANCREAS;

EID: 84904268882     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102198     Document Type: Article

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