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Volumn 74, Issue 14, 2014, Pages 3740-3752

Autophagy inhibition by sustained overproduction of IL6 contributes to arsenic carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC; BECLIN 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN MCL 1; STAT3 PROTEIN;

EID: 84904268484     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3182     Document Type: Article
Times cited : (68)

References (44)
  • 1
    • 33750497844 scopus 로고    scopus 로고
    • Inflammation and cancer: How hot is the link?
    • DOI 10.1016/j.bcp.2006.06.029, PII S0006295206003893, Cell Signalling, Transcription and Translation as Therapeutic Tergets
    • Aggarwal BB, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link? Biochem Pharmacol 2006;72:1605-21. (Pubitemid 44666739)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.11 , pp. 1605-1621
    • Aggarwal, B.B.1    Shishodia, S.2    Sandur, S.K.3    Pandey, M.K.4    Sethi, G.5
  • 3
    • 79960122931 scopus 로고    scopus 로고
    • Dual roles of immune cells and their factors in cancer development and progression
    • Zamarron BF, Chen W. Dual roles of immune cells and their factors in cancer development and progression. Int J Biol Sci 2011;7:651-8.
    • (2011) Int J Biol Sci , vol.7 , pp. 651-658
    • Zamarron, B.F.1    Chen, W.2
  • 4
    • 0042209597 scopus 로고    scopus 로고
    • Serum interleukin-6 levels reflect the disease status of colorectal cancer
    • Chung YC, Chang YF. Serum interleukin-6 levels reflect the disease status of colorectal cancer. J Surg Oncol 2003;83:222-6.
    • (2003) J Surg Oncol , vol.83 , pp. 222-226
    • Chung, Y.C.1    Chang, Y.F.2
  • 6
    • 0042889276 scopus 로고    scopus 로고
    • Roles of keratinocyte inflammation in oral cancer: Regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline
    • Jeng JH, Wang YJ, Chiang BL, Lee PH, Chan CP, Ho YS, et al. Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. Carcinogenesis 2003;24:1301-15.
    • (2003) Carcinogenesis , vol.24 , pp. 1301-1315
    • Jeng, J.H.1    Wang, Y.J.2    Chiang, B.L.3    Lee, P.H.4    Chan, C.P.5    Ho, Y.S.6
  • 7
    • 84862888230 scopus 로고    scopus 로고
    • Autophagy: An emerging immunological paradigm
    • Deretic V. Autophagy: an emerging immunological paradigm. J Immunol 2012;189:15-20.
    • (2012) J Immunol , vol.189 , pp. 15-20
    • Deretic, V.1
  • 9
    • 79251589356 scopus 로고    scopus 로고
    • Autophagy negatively regulates keratinocyte inflammatory responses via scaffolding protein p62/SQSTM1
    • Lee HM, Shin DM, Yuk JM, Shi G, Choi DK, Lee SH, et al. Autophagy negatively regulates keratinocyte inflammatory responses via scaffolding protein p62/SQSTM1. J Immunol 2011;186:1248-58.
    • (2011) J Immunol , vol.186 , pp. 1248-1258
    • Lee, H.M.1    Shin, D.M.2    Yuk, J.M.3    Shi, G.4    Choi, D.K.5    Lee, S.H.6
  • 11
    • 67449098637 scopus 로고    scopus 로고
    • Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer
    • Lee G, Walser TC, Dubinett SM. Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer. Curr Opin Pulm Med 2009;15:303-7.
    • (2009) Curr Opin Pulm Med , vol.15 , pp. 303-307
    • Lee, G.1    Walser, T.C.2    Dubinett, S.M.3
  • 12
    • 84878745464 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in arsenic-transformed cells promotes angiogenesis through activating beta-catenin-vascular endothelial growth factor pathway
    • Wang Z, Humphries B, Xiao H, Jiang Y, Yang C. Epithelial to mesenchymal transition in arsenic-transformed cells promotes angiogenesis through activating beta-catenin-vascular endothelial growth factor pathway. Toxicol Appl Pharmacol 2013;271:20-9.
    • (2013) Toxicol Appl Pharmacol , vol.271 , pp. 20-29
    • Wang, Z.1    Humphries, B.2    Xiao, H.3    Jiang, Y.4    Yang, C.5
  • 13
    • 84861010990 scopus 로고    scopus 로고
    • Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells
    • Stueckle TA, Lu Y, Davis ME, Wang L, Jiang BH, Holaskova I, et al. Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Toxicol Appl Pharmacol 2012;261:204-16.
    • (2012) Toxicol Appl Pharmacol , vol.261 , pp. 204-216
    • Stueckle, T.A.1    Lu, Y.2    Davis, M.E.3    Wang, L.4    Jiang, B.H.5    Holaskova, I.6
  • 14
    • 84869393183 scopus 로고    scopus 로고
    • Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation
    • Zhang T, Qi Y, Liao M, Xu M, Bower KA, Frank JA, et al. Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation. Toxicol Sci 2012;130:298-308.
    • (2012) Toxicol Sci , vol.130 , pp. 298-308
    • Zhang, T.1    Qi, Y.2    Liao, M.3    Xu, M.4    Bower, K.A.5    Frank, J.A.6
  • 16
    • 9444257518 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine- induced neuronal death
    • DOI 10.1096/fj.04-1551fje
    • Chen G, Bower KA,MaC, Fang S, Thiele CJ, Luo J. Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death. FASEB J. 2004;18:1162-4. (Pubitemid 39561557)
    • (2004) FASEB Journal , vol.18 , Issue.10 , pp. 1162-1164
    • Chen, G.1    Bower, K.A.2    Ma, C.3    Fang, S.4    Thiele, C.J.5    Luo, J.6
  • 18
    • 84884146830 scopus 로고    scopus 로고
    • Involvement of HIF-2alpha-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells
    • Xu Y, Zhao Y, Xu W, Luo F, Wang B, Li Y, et al. Involvement of HIF-2alpha-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells. Toxicol Appl Pharmacol 2013;272:542-50.
    • (2013) Toxicol Appl Pharmacol , vol.272 , pp. 542-550
    • Xu, Y.1    Zhao, Y.2    Xu, W.3    Luo, F.4    Wang, B.5    Li, Y.6
  • 19
    • 38749136302 scopus 로고    scopus 로고
    • Regulation of macroautophagy by mTOR and Beclin 1 complexes
    • DOI 10.1016/j.biochi.2007.08.014, PII S0300908407002283
    • Pattingre S, Espert L, Biard-Piechaczyk M, Codogno P. Regulation of macroautophagy by mTOR and Beclin 1 complexes. Biochimie 2008;90:313-23. (Pubitemid 351181247)
    • (2008) Biochimie , vol.90 , Issue.2 , pp. 313-323
    • Pattingre, S.1    Espert, L.2    Biard-Piechaczyk, M.3    Codogno, P.4
  • 20
    • 76349098949 scopus 로고    scopus 로고
    • Crosstalk between apoptosis and autophagy within the Beclin 1 interactome
    • Maiuri MC, Criollo A, Kroemer G. Crosstalk between apoptosis and autophagy within the Beclin 1 interactome. EMBO J 2010;29:515-6.
    • (2010) EMBO J , vol.29 , pp. 515-516
    • Maiuri, M.C.1    Criollo, A.2    Kroemer, G.3
  • 21
    • 70350550208 scopus 로고    scopus 로고
    • Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
    • Spencer B, Potkar R, Trejo M, Rockenstein E, Patrick C, Gindi R, et al. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J Neurosci 2009;29:13578-88.
    • (2009) J Neurosci , vol.29 , pp. 13578-13588
    • Spencer, B.1    Potkar, R.2    Trejo, M.3    Rockenstein, E.4    Patrick, C.5    Gindi, R.6
  • 22
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011;18:571-80.
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 23
    • 35348951458 scopus 로고    scopus 로고
    • Therapeutic strategies for targeting the IL-6/STAT3 cytokine signaling pathway in inflammatory bowel disease
    • Mitsuyama K, Matsumoto S, Masuda J, Yamasakii H, Kuwaki K, Takedatsu H, et al. Therapeutic strategies for targeting the IL-6/STAT3 cytokine signaling pathway in inflammatory bowel disease. Anticancer Res 2007;27:3749-56. (Pubitemid 47598440)
    • (2007) Anticancer Research , vol.27 , Issue.6 A , pp. 3749-3756
    • Mitsuyama, K.1    Matsumoto, S.2    Masuda, J.3    Yamasaki, H.4    Kuwaki, K.5    Takedatsu, H.6    Sata, M.7
  • 26
    • 46749085910 scopus 로고    scopus 로고
    • Mcl-1 is regulated by IL-6 and mediates the survival activity of the cytokine in a model of late stage prostate carcinoma
    • Cavarretta IT, Neuwirt H, Zaki MH, Steiner H, Hobisch A, Nemeth JA, et al. Mcl-1 is regulated by IL-6 and mediates the survival activity of the cytokine in a model of late stage prostate carcinoma. Adv ExpMed Biol 2008;617:547-55.
    • (2008) Adv ExpMed Biol , vol.617 , pp. 547-555
    • Cavarretta, I.T.1    Neuwirt, H.2    Zaki, M.H.3    Steiner, H.4    Hobisch, A.5    Nemeth, J.A.6
  • 27
    • 78751621004 scopus 로고    scopus 로고
    • MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner
    • Germain M, Nguyen AP, Le Grand JN, Arbour N, Vanderluit JL, Park DS, et al. MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. EMBO J 2011;30:395-407.
    • (2011) EMBO J , vol.30 , pp. 395-407
    • Germain, M.1    Nguyen, A.P.2    Le Grand, J.N.3    Arbour, N.4    Vanderluit, J.L.5    Park, D.S.6
  • 28
    • 29144528036 scopus 로고    scopus 로고
    • STAT3-mediated transcription of Bcl-2, Mcl-1 and C-IAP2 prevents apoptosis in polyamine-depleted cells
    • DOI 10.1042/BJ20050465
    • Bhattacharya S, Ray RM, Johnson LR. STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells. Biochem J 2005;392:335-44. (Pubitemid 41796522)
    • (2005) Biochemical Journal , vol.392 , Issue.2 , pp. 335-344
    • Bhattacharya, S.1    Ray, R.M.2    Johnson, L.R.3
  • 29
    • 0032711250 scopus 로고    scopus 로고
    • IL-6 up-regulates mcl-1 in human myeloma cells through JAK / STAT rather than ras / MAP kinase pathway
    • Puthier D, Bataille R, Amiot M. IL-6 up-regulates mcl-1 in human myeloma cells through JAK / STAT rather than ras / MAP kinase pathway. Eur J Immunol 1999;29:3945-50.
    • (1999) Eur J Immunol , vol.29 , pp. 3945-3950
    • Puthier, D.1    Bataille, R.2    Amiot, M.3
  • 30
    • 84874786609 scopus 로고    scopus 로고
    • Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway
    • Yang F, Zhang W, Li D, Zhan Q. Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway. J Biol Chem 2013;288:6552-60.
    • (2013) J Biol Chem , vol.288 , pp. 6552-6560
    • Yang, F.1    Zhang, W.2    Li, D.3    Zhan, Q.4
  • 31
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker T, Kovarik P. Serine phosphorylation of STATs. Oncogene 2000;19:2628-37. (Pubitemid 30339219)
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 33
    • 84855466316 scopus 로고    scopus 로고
    • Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells
    • Escudero-Lourdes C, Wu T, Camarillo JM, Gandolfi AJ. Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells. Toxicol Appl Pharmacol 2012;258:10-8.
    • (2012) Toxicol Appl Pharmacol , vol.258 , pp. 10-18
    • Escudero-Lourdes, C.1    Wu, T.2    Camarillo, J.M.3    Gandolfi, A.J.4
  • 34
    • 84856002234 scopus 로고    scopus 로고
    • Autophagy: Cellular defense to excessive inflammation
    • Jo EK, Shin DM, Choi AM. Autophagy: cellular defense to excessive inflammation. Microbes Infect 2012;14:119-25.
    • (2012) Microbes Infect , vol.14 , pp. 119-125
    • Jo, E.K.1    Shin, D.M.2    Choi, A.M.3
  • 35
    • 84862281540 scopus 로고    scopus 로고
    • Interleukin-6: A bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cells
    • Delk NA, Farach-Carson MC. Interleukin-6: a bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cells. Autophagy 2012;8:650-63.
    • (2012) Autophagy , vol.8 , pp. 650-663
    • Delk, N.A.1    Farach-Carson, M.C.2
  • 36
    • 84879800679 scopus 로고    scopus 로고
    • Promotion of autophagy at the maturation step by IL-6 is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity
    • Li XZ, Sui CY, Chen Q, Chen XP, Zhang H, Zhou XP. Promotion of autophagy at the maturation step by IL-6 is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity. Mol Cell Biochem 2013;380:219-27.
    • (2013) Mol Cell Biochem , vol.380 , pp. 219-227
    • Li, X.Z.1    Sui, C.Y.2    Chen, Q.3    Chen, X.P.4    Zhang, H.5    Zhou, X.P.6
  • 37
    • 84860284485 scopus 로고    scopus 로고
    • IL-6 inhibits IFN-gamma induced autophagy in Mycobacterium tuberculosis H37Rv infected macrophages
    • Dutta RK, Kathania M, Raje M, Majumdar S. IL-6 inhibits IFN-gamma induced autophagy in Mycobacterium tuberculosis H37Rv infected macrophages. Int J Biochem Cell Biol 2012;44:942-54.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 942-954
    • Dutta, R.K.1    Kathania, M.2    Raje, M.3    Majumdar, S.4
  • 38
    • 84864652172 scopus 로고    scopus 로고
    • Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy
    • Parys JB, Decuypere JP, Bultynck G. Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy. Cell Commun Signal 2012;10:17.
    • (2012) Cell Commun Signal , vol.10 , pp. 17
    • Parys, J.B.1    Decuypere, J.P.2    Bultynck, G.3
  • 39
    • 48249092267 scopus 로고    scopus 로고
    • Bcl-2 family members: Dual regulators of apoptosis and autophagy
    • Levine B, Sinha S, Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 2008;4:600-6.
    • (2008) Autophagy , vol.4 , pp. 600-606
    • Levine, B.1    Sinha, S.2    Kroemer, G.3
  • 40
    • 84864883249 scopus 로고    scopus 로고
    • AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway
    • Kang R, Tang D, Lotze MT, Zeh HJ III. AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway. Autophagy 2012;8:989-91.
    • (2012) Autophagy , vol.8 , pp. 989-991
    • Kang, R.1    Tang, D.2    Lotze, M.T.3    Zeh III, H.J.4
  • 41
    • 84860813449 scopus 로고    scopus 로고
    • The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia
    • Kang R, Loux T, Tang D, Schapiro NE, Vernon P, Livesey KM, et al. The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia. Proc Natl Acad Sci U S A 2012;109:7031-6.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 7031-7036
    • Kang, R.1    Loux, T.2    Tang, D.3    Schapiro, N.E.4    Vernon, P.5    Livesey, K.M.6
  • 44
    • 77649289360 scopus 로고    scopus 로고
    • Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells
    • Priault M, Hue E, Marhuenda F, Pilet P, Oliver L, Vallette FM. Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. PLoS One 2010;5:e8755.
    • (2010) PLoS One , vol.5
    • Priault, M.1    Hue, E.2    Marhuenda, F.3    Pilet, P.4    Oliver, L.5    Vallette, F.M.6


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