-
1
-
-
84861880572
-
Strategies for the discovery and development of therapies for metastatic breast cancer
-
Eckhardt BL, Francis PA, Parker BS, Anderson RL. Strategies for the discovery and development of therapies for metastatic breast cancer. Nat Rev Drug Discov 2012; 11: 479-497.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 479-497
-
-
Eckhardt, B.L.1
Francis, P.A.2
Parker, B.S.3
Anderson, R.L.4
-
2
-
-
33746851956
-
Tumor metastasis: Mechanistic insights and clinical challenges
-
DOI 10.1038/nm1469, PII NM1469
-
Steeg PS. Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 2006; 12: 895-904. (Pubitemid 44175140)
-
(2006)
Nature Medicine
, vol.12
, Issue.8
, pp. 895-904
-
-
Steeg, P.S.1
-
3
-
-
0027140406
-
Extracellular matrix 6: Role of matrix metalloproteinases in tumor invasion and metastasis
-
Stetler-Stevenson WG, Liotta LA, Kleiner Jr DE. Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis. FASEB J 1993; 7: 1434-1441. (Pubitemid 24003262)
-
(1993)
FASEB Journal
, vol.7
, Issue.15
, pp. 1434-1441
-
-
Stetler-Stevenson, W.G.1
Liotta, L.A.2
Kleiner Jr., D.E.3
-
4
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
DOI 10.1158/0008-5472.CAN-05-1783
-
Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65: 7065-7070. (Pubitemid 41161233)
-
(2005)
Cancer Research
, vol.65
, Issue.16
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.-G.3
Veronese, A.4
Spizzo, R.5
Sabbioni, S.6
Magri, E.7
Pedriali, M.8
Fabbri, M.9
Campiglio, M.10
Menard, S.11
Palazzo, J.P.12
Rosenberg, A.13
Musiani, P.14
Volinia, S.15
Nenci, I.16
Calin, G.A.17
Querzoli, P.18
Negrini, M.19
Croce, C.M.20
more..
-
5
-
-
66349088326
-
MicroRNA involvement in the pathogenesis and management of breast cancer
-
Khoshnaw SM, Green AR, Powe DG, Ellis IO. MicroRNA involvement in the pathogenesis and management of breast cancer. J Clin Pathol 2009; 62: 422-428.
-
(2009)
J Clin Pathol
, vol.62
, pp. 422-428
-
-
Khoshnaw, S.M.1
Green, A.R.2
Powe, D.G.3
Ellis, I.O.4
-
6
-
-
84861345640
-
MicroRNA-mediated breast cancer metastasis: From primary site to distant organs
-
Wang L, Wang J. MicroRNA-mediated breast cancer metastasis: from primary site to distant organs. Oncogene 2012; 31: 2499-2511.
-
(2012)
Oncogene
, vol.31
, pp. 2499-2511
-
-
Wang, L.1
Wang, J.2
-
7
-
-
70350233470
-
Metastamir: The field of metastasis-regulatory microRNA is spreading
-
Hurst DR, Edmonds MD, Welch DR. Metastamir: the field of metastasis-regulatory microRNA is spreading. Cancer Res 2009; 69: 7495-7498.
-
(2009)
Cancer Res
, vol.69
, pp. 7495-7498
-
-
Hurst, D.R.1
Edmonds, M.D.2
Welch, D.R.3
-
8
-
-
79952198180
-
Metastasis-related miRNAs, active players in breast cancer invasion, and metastasis
-
Shi M, Liu D, Duan H, Shen B, Guo N. Metastasis-related miRNAs, active players in breast cancer invasion, and metastasis. Cancer Metastasis Rev 2010; 29: 785-799.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 785-799
-
-
Shi, M.1
Liu, D.2
Duan, H.3
Shen, B.4
Guo, N.5
-
9
-
-
84862883653
-
Role of estrogen receptor signaling in breast cancer metastasis
-
Saha RS, Vadlamudi RK. Role of estrogen receptor signaling in breast cancer metastasis. Int J Breast Cancer 2012; 2012: 654698.
-
(2012)
Int J Breast Cancer
, vol.2012
, pp. 654-698
-
-
Saha, R.S.1
Vadlamudi, R.K.2
-
10
-
-
33748991736
-
Molecular biology Little molecules with big goals
-
OMalley BW. Molecular biology. Little molecules with big goals. Science 2006; 313: 1749-1750.
-
(2006)
Science
, vol.313
, pp. 1749-1750
-
-
Omalley, B.W.1
-
11
-
-
33744792310
-
Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
-
DOI 10.1101/gad.1424806
-
Rosenfeld MG, Lunyak VV, Glass CK. Sensors and signals: a coactivator/ corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev 2006; 20: 1405-1428. (Pubitemid 43830648)
-
(2006)
Genes and Development
, vol.20
, Issue.11
, pp. 1405-1428
-
-
Rosenfeld, M.G.1
Lunyak, V.V.2
Glass, C.K.3
-
12
-
-
28744431757
-
Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: Implicated role of growth factor signaling and estrogen receptor coregulators
-
Schiff R, Massarweh SA, Shou J, Bharwani L, Arpino G, Rimawi M et al. Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulators. Cancer Chemother Pharmacol 2005; 56(Suppl 1): 10-2010-20.
-
(2005)
Cancer Chemother Pharmacol
, vol.56 SUPPL 1
, pp. 1020-1020
-
-
Schiff, R.1
Massarweh, S.A.2
Shou, J.3
Bharwani, L.4
Arpino, G.5
Rimawi, M.6
-
13
-
-
84860246473
-
Emerging significance of estrogen cancer coregulator signaling in breast cancer
-
Mann M, Krishnan S, Vadlamudi RK. Emerging significance of estrogen cancer coregulator signaling in breast cancer. Minerva Ginecol 2012; 64: 75-88.
-
(2012)
Minerva Ginecol
, vol.64
, pp. 75-88
-
-
Mann, M.1
Krishnan, S.2
Vadlamudi, R.K.3
-
14
-
-
34250881447
-
Coregulators: From whence came these "master genes"
-
OMalley BW. Coregulators: from whence came these "master genes". Mol Endocrinol 2007; 21: 1009-1013.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1009-1013
-
-
Omalley, B.W.1
-
15
-
-
34250619620
-
Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR
-
Vadlamudi RK, Kumar R. Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR. Nucl Recept Signal 2007; 5:e004.
-
(2007)
Nucl Recept Signal
, vol.5
-
-
Vadlamudi, R.K.1
Kumar, R.2
-
16
-
-
77951129233
-
PELP1: A novel therapeutic target for hormonal cancers
-
Chakravarty D, Tekmal RR, Vadlamudi RK. PELP1: A novel therapeutic target for hormonal cancers. IUBMB Life 2010; 62: 162-169.
-
(2010)
IUBMB Life
, vol.62
, pp. 162-169
-
-
Chakravarty, D.1
Tekmal, R.R.2
Vadlamudi, R.K.3
-
17
-
-
34347208713
-
Oncogenic potential of the nuclear receptor coregulator proline-, glutamic acid-, leucine-rich protein 1/modulator of the nongenomic actions of the estrogen receptor
-
DOI 10.1158/0008-5472.CAN-06-3647
-
Rajhans R, Nair S, Holden AH, Kumar R, Tekmal RR, Vadlamudi RK. Oncogenic potential of the nuclear receptor coregulator proline-, glutamic acid-, leucine-rich protein 1/modulator of the nongenomic actions of the estrogen receptor. Cancer Res 2007; 67: 5505-5512. (Pubitemid 46997292)
-
(2007)
Cancer Research
, vol.67
, Issue.11
, pp. 5505-5512
-
-
Rajhans, R.1
Nair, S.2
Holden, A.H.3
Kumar, R.4
Tekmal, R.R.5
Vadlamudi, R.K.6
-
18
-
-
84855990646
-
Significance of PELP1 in ER-negative breast cancer metastasis
-
Roy S, Chakravarty D, Cortez V, De MK, Bandyopadhyay A, Ahn JM et al. Significance of PELP1 in ER-negative breast cancer metastasis. Mol Cancer Res 2012; 10: 25-33.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 25-33
-
-
Roy, S.1
Chakravarty, D.2
Cortez, V.3
De, M.K.4
Bandyopadhyay, A.5
Ahn, J.M.6
-
19
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
DOI 10.1038/ncb1722, PII NCB1722
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10: 593-601. (Pubitemid 351627379)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.5
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
20
-
-
77956914563
-
Cyclindependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1
-
Nair BC, Nair SS, Chakravarty D, Challa R, Manavathi B, Yew PR et al. Cyclindependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1. Cancer Res 2010; 70: 7166-7175.
-
(2010)
Cancer Res
, vol.70
, pp. 7166-7175
-
-
Nair, B.C.1
Nair, S.S.2
Chakravarty, D.3
Challa, R.4
Manavathi, B.5
Yew, P.R.6
-
21
-
-
79954624183
-
Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis
-
Chakravarty D, Roy SS, Babu CR, Dandamudi R, Curiel TJ, Vivas-Mejia P et al. Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis. Clin Cancer Res 2011; 17: 2250-2259.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2250-2259
-
-
Chakravarty, D.1
Roy, S.S.2
Babu, C.R.3
Dandamudi, R.4
Curiel, T.J.5
Vivas-Mejia, P.6
-
22
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
-
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 2008; 68: 7846-7854.
-
(2008)
Cancer Res
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Wang, J.5
Shannon, M.F.6
-
23
-
-
79953329774
-
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200- dependent pathway in mice
-
Yang Y, Ahn YH, Gibbons DL, Zang Y, Lin W, Thilaganathan N et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200- dependent pathway in mice. J Clin Invest 2011; 121: 1373-1385.
-
(2011)
J Clin Invest
, vol.121
, pp. 1373-1385
-
-
Yang, Y.1
Ahn, Y.H.2
Gibbons, D.L.3
Zang, Y.4
Lin, W.5
Thilaganathan, N.6
-
24
-
-
79551469293
-
Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer
-
Wiklund ED, Bramsen JB, Hulf T, Dyrskjot L, Ramanathan R, Hansen TB et al. Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. Int J Cancer 2011; 128: 1327-1334.
-
(2011)
Int J Cancer
, vol.128
, pp. 1327-1334
-
-
Wiklund, E.D.1
Bramsen, J.B.2
Hulf, T.3
Dyrskjot, L.4
Ramanathan, R.5
Hansen, T.B.6
-
25
-
-
10944229755
-
The transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domains
-
DOI 10.1074/jbc.M406831200
-
Choi YB, Ko JK, Shin J. The transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domains. J Biol Chem 2004; 279: 50930-50941. (Pubitemid 40017832)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.49
, pp. 50930-50941
-
-
Young, B.C.1
Jin, K.K.2
Shin, J.3
-
26
-
-
84864913725
-
Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer
-
Cortez V, Mann M, Tekmal S, Suzuki T, Miyata N, Rodriguez-Aguayo C et al. Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer. Breast Cancer Res 2012; 14: R108.
-
(2012)
Breast Cancer Res
, vol.14
-
-
Cortez, V.1
Mann, M.2
Tekmal, S.3
Suzuki, T.4
Miyata, N.5
Rodriguez-Aguayo, C.6
-
27
-
-
67650996280
-
Epithelialmesenchymal transitions: The importance of changing cell state in development and disease
-
Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA. Epithelialmesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest 2009; 119: 1438-1449.
-
(2009)
J Clin Invest
, vol.119
, pp. 1438-1449
-
-
Acloque, H.1
Adams, M.S.2
Fishwick, K.3
Bronner-Fraser, M.4
Nieto, M.A.5
-
28
-
-
70350537033
-
Nuclear receptor coregulators in cancer biology
-
OMalley BW, Kumar R. Nuclear receptor coregulators in cancer biology. Cancer Res 2009; 69: 8217-8222.
-
(2009)
Cancer Res
, vol.69
, pp. 8217-8222
-
-
Omalley, B.W.1
Kumar, R.2
-
29
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
DOI 10.1038/embor.2008.74, PII EMBOR200874
-
Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008; 9: 582-589. (Pubitemid 351772923)
-
(2008)
EMBO Reports
, vol.9
, Issue.6
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
Schmalhofer, O.4
Vincan, E.5
Spaderna, S.6
Brabletz, T.7
-
30
-
-
44449111555
-
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
-
Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 2008; 68: 3645-3654.
-
(2008)
Cancer Res
, vol.68
, pp. 3645-3654
-
-
Onder, T.T.1
Gupta, P.B.2
Mani, S.A.3
Yang, J.4
Lander, E.S.5
Weinberg, R.A.6
-
31
-
-
0033853424
-
The E-cadherin-catenin complex in tumour metastasisstructure, function and regulation
-
DOI 10.1016/S0959-8049(00)00158-1, PII S0959804900001581
-
Beavon IR. The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation. Eur J Cancer 2000; 36(13 Spec No): 1607-1620. (Pubitemid 30616365)
-
(2000)
European Journal of Cancer
, vol.36
, Issue.13
, pp. 1607-1620
-
-
Beavon, I.R.G.1
-
32
-
-
0035146442
-
Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor
-
DOI 10.1038/35050532
-
Mazumdar A, Wang RA, Mishra SK, Adam L, Bagheri-Yarmand R, Mandal M et al. Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor. Nat Cell Biol 2001; 3: 30-37. (Pubitemid 32114829)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.1
, pp. 30-37
-
-
Mazumdar, A.1
Wang, R.-A.2
Mishra, S.K.3
Adam, L.4
Bagheri-Yarmand, R.5
Mandal, M.6
Vadlamudi, R.K.7
Kumar, R.8
-
33
-
-
52649149854
-
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression
-
Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H et al. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol 2008; 28: 5937-5950.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5937-5950
-
-
Qin, L.1
Liao, L.2
Redmond, A.3
Young, L.4
Yuan, Y.5
Chen, H.6
-
34
-
-
65949098187
-
The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis
-
Qin L, Liu Z, Chen H, Xu J. The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis. Cancer Res 2009; 69: 3819-3827.
-
(2009)
Cancer Res
, vol.69
, pp. 3819-3827
-
-
Qin, L.1
Liu, Z.2
Chen, H.3
Xu, J.4
-
35
-
-
77950858916
-
The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype
-
Habashy HO, Powe DG, Rakha EA, Ball G, Macmillan RD, Green AR et al. The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype. Breast Cancer Res Treat 2009; 120: 603-612.
-
(2009)
Breast Cancer Res Treat
, vol.120
, pp. 603-612
-
-
Habashy, H.O.1
Powe, D.G.2
Rakha, E.A.3
Ball, G.4
Macmillan, R.D.5
Green, A.R.6
-
36
-
-
33847194532
-
Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-A-half LIM-only protein 2
-
Nair SS, Guo Z, Mueller JM, Koochekpour S, Qiu Y, Tekmal RR et al. Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2. Mol Endocrinol 2007; 21: 613-624.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 613-624
-
-
Nair, S.S.1
Guo, Z.2
Mueller, J.M.3
Koochekpour, S.4
Qiu, Y.5
Tekmal, R.R.6
-
37
-
-
77952823885
-
Extranuclear functions of ER impact invasive migration and metastasis by breast cancer cells
-
Chakravarty D, Nair SS, Santhamma B, Nair BC, Wang L, Bandyopadhyay A et al. Extranuclear functions of ER impact invasive migration and metastasis by breast cancer cells. Cancer Res 2010; 70: 4092-4101.
-
(2010)
Cancer Res
, vol.70
, pp. 4092-4101
-
-
Chakravarty, D.1
Nair, S.S.2
Santhamma, B.3
Nair, B.C.4
Wang, L.5
Bandyopadhyay, A.6
-
38
-
-
79952283482
-
P53 regulates epithelialmesenchymal transition and stem cell properties through modulating miRNAs
-
Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW et al. p53 regulates epithelialmesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol 2011; 13: 317-323.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 317-323
-
-
Chang, C.J.1
Chao, C.H.2
Xia, W.3
Yang, J.Y.4
Xiong, Y.5
Li, C.W.6
-
39
-
-
77953121401
-
PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity
-
Nair SS, Nair BC, Cortez V, Chakravarty D, Metzger E, Schule R et al. PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity. EMBO Rep 2010; 11: 438-444.
-
(2010)
EMBO Rep
, vol.11
, pp. 438-444
-
-
Nair, S.S.1
Nair, B.C.2
Cortez, V.3
Chakravarty, D.4
Metzger, E.5
Schule, R.6
-
40
-
-
77953765387
-
Doxorubicin in combination with a small TGFbeta inhibitor: A potential novel therapy for metastatic breast cancer in mouse models
-
Bandyopadhyay A, Wang L, Agyin J, Tang Y, Lin S, Yeh IT et al. Doxorubicin in combination with a small TGFbeta inhibitor: a potential novel therapy for metastatic breast cancer in mouse models. PLoS One 2010; 5: e10365.
-
(2010)
PLoS One
, vol.5
-
-
Bandyopadhyay, A.1
Wang, L.2
Agyin, J.3
Tang, Y.4
Lin, S.5
Yeh, I.T.6
-
41
-
-
78149478716
-
Novel design principles enable specific targeting of imaging and therapeutic agents to necrotic domains in breast tumors
-
Goldshaid L, Rubinstein E, Brandis A, Segal D, Leshem N, Brenner O et al. Novel design principles enable specific targeting of imaging and therapeutic agents to necrotic domains in breast tumors. Breast Cancer Res 2010; 12: R29.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Goldshaid, L.1
Rubinstein, E.2
Brandis, A.3
Segal, D.4
Leshem, N.5
Brenner, O.6
-
42
-
-
33644800080
-
Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice
-
Jenkins DE, Hornig YS, Oei Y, Dusich J, Purchio T. Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice. Breast Cancer Res 2005; 7: R444-R454.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Jenkins, D.E.1
Hornig, Y.S.2
Oei, Y.3
Dusich, J.4
Purchio, T.5
|