Structure-function analysis of RAMP1 by alanine mutagenesis

Biochemistry

Volumn 48, Issue 1, 2009, Pages 198-205

  Simms, John ^a,b   Hay, Debbie L ^a,c   Bailey, Richard J ^c   Konycheva, Galina ^c   Bailey, Graham ^c   Wheatley, Mark ^d   Poyner, David R ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACES; INTEGRAL COMPONENTS; LIGAND BINDING; PROTEIN INTERACTIONS; RECEPTOR ACTIVITY; RECEPTOR TRAFFICKING; RECOGNITION SITES; STRUCTURE FUNCTION ANALYSIS;

AMINES; BIOCHEMISTRY; CELL MEMBRANES; MUTAGENESIS;

FETAL MONITORING;

ALANINE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN RECEPTOR LIKE RECEPTOR; CYCLIC AMP; MUTANT PROTEIN; RECEPTOR ACTIVITY MODIFYING PROTEIN 1;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CELL STRAIN COS7; CELL SURFACE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ADRENOMEDULLIN; ALANINE; AMINO ACID SEQUENCE; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; COS CELLS; CYCLIC AMP; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; RECEPTORS, CALCITONIN; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 58549084401     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801869n     Document Type: Article

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