Critical parameters involved in producing microspheres by prilling of molten lipids: From theoretical prediction of particle size to practice

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 87, Issue 3, 2014, Pages 530-540

  Sequier F ^a,b   Faivre, V ^a   Daste, G ^b   Renouard, M ^b   Lesieur, S ^a  

^a UNIV PARIS SUD   (France)

^b SANOFI   (France)

Author keywords

Jet break up; Lipid; Microsphere; Orifice coefficient; Prilling; Rayleigh Weber; Viscosity

Indexed keywords

FAT DROPLET; LIPID; MICROSPHERE;

ARTICLE; COOLING; FLOW KINETICS; LIPID ANALYSIS; LIQUID; MELTING POINT; PARTICLE SIZE; PRESSURE; SURFACE TENSION; TEMPERATURE; VISCOSITY; CHEMISTRY; MEDICINAL CHEMISTRY; PROCEDURES; SURFACE PROPERTY;

CHEMISTRY, PHARMACEUTICAL; LIPIDS; MICROSPHERES; PARTICLE SIZE; SURFACE PROPERTIES; SURFACE TENSION; TEMPERATURE; VISCOSITY;

EID: 84904252961     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.03.005     Document Type: Article

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