A new single nucleotide polymorphism in the rabbit (Oryctolagus cuniculus) myostatin (MSTN) gene is associated with carcass composition traits

Animal Genetics

Volumn 45, Issue 4, 2014, Pages 596-599

  Sternstein, Ina ^a   Reissmann, Monika ^a   Maj, Dorota ^b   Bieniek, Josef ^b   Brockmann, Gudrun A ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF AGRICULTURE IN KRAKOW   (Poland)

Author keywords

cross bred population; gene variation; haplotype; meat quality; muscle mass

Indexed keywords

MYOSTATIN;

ANALYSIS; ANIMAL; BODY COMPOSITION; DNA SEQUENCE; GENETIC LINKAGE; GENETICS; MEAT; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RABBIT; SEQUENCE ALIGNMENT; SINGLE NUCLEOTIDE POLYMORPHISM; VETERINARY;

ANIMALS; BODY COMPOSITION; GENETIC LINKAGE; MEAT; MOLECULAR SEQUENCE DATA; MYOSTATIN; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RABBITS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA;

EID: 84904111780     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/age.12165     Document Type: Article

References (13)

1. Boman I.A., Klemetsdal G., Blichfeldt T., Nafstad O., &, Vage D.I., (2009) A frameshift mutation in the coding region of the myostatin gene (MSTN) affects carcass conformation and fatness in Norwegian White Sheep (Ovis aries). Animal Genetics 40, 418-22.
2. Boman I.A., Klemetsdal G., Nafstad O., Blichfeldt T., &, Vage D.I., (2010) Impact of two myostatin (MSTN) mutations on weight gain and lamb carcass classification in Norwegian White Sheep (Ovis aries). Genetics, Selection, Evolution 42, 4.
3. Butter F., Kappei D., Buchholz F., Vermeulen M., &, Mann M., (2010) A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth. EMBO Reports 11, 305-11.
4. Clop A., Marcq F., Takeda H., et al,. (2006) A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nature Genetics 38, 813-8.
5. Davidovich O., Kimmel G., &, Shamir R., (2007) gevalt: an integrated software tool for genotype analysis. BMC Bioinformatics 8, 36.
6. Fontanesi L., Scotti E., Frabetti A., Fornasini D., Picconi A., &, Russo V., (2011) Identification of polymorphisms in the rabbit (Oryctolagus cuniculus) myostatin (MSTN) gene and association analysis with finishing weight in a commercial rabbit population. Animal Genetics 42, 339.
7. Grobet L., Martin L.J., Poncelet D., et al,. (1997) A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nature Genetics 17, 71-4.
8. Kreuzer S., Reissmann M., &, Brockmann G.A., (2013) Gene test to elucidate the ETEC F4ab/F4ac receptor status in pigs. Veterinary Microbiology 162, 293-5.
9. McPherron A.C., &, Lee S.J., (1997) Double muscling in cattle due to mutations in the myostatin gene. Proceedings of the National Academy of Sciences of the United States of America 94, 12457-61.
10. McPherron A.C., Lawler A.M., &, Lee S.J., (1997) Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387, 83-90.
11. Schuelke M., Wagner K.R., Stolz L.E., Hubner C., Riebel T., Komen W., Braun T., Tobin J.F., &, Lee S.J., (2004) Myostatin mutation associated with gross muscle hypertrophy in a child. New England Journal of Medicine 350, 2682-8.
12. Stinckens A., Luyten T., Bijttebier J., Van den Maagdenberg K., Dieltiens D., Janssens S., De Smet S., Georges M., &, Buys N., (2008) Characterization of the complete porcine MSTN gene and expression levels in pig breeds differing in muscularity. Animal Genetics 39, 586-96.
13. Van Laere A.S., Nguyen M., Braunschweig M., et al,. (2003) A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig. Nature 425, 832-6.