Optical coherence tomography imaging of erythematotelangiectatic rosacea during treatment with brimonidine topical gel 0.33%: A potential method for treatment outcome assessment

Journal of Drugs in Dermatology

Volumn 13, Issue 7, 2014, Pages 821-826

  Urban, Jennifer ^a   Siripunvarapon, Arunee H ^b   Meekings, Adam ^c   Kalowitz, Amy ^b   Markowitz, Orit ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c 11A Grays Farm Production Village   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AZELAIC ACID; BRIMONIDINE; METRONIDAZOLE; TETRACYCLINE DERIVATIVE; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; GEL; QUINOXALINE DERIVATIVE;

ADULT; ARTICLE; BLOOD VESSEL DIAMETER; CASE REPORT; CASE STUDY; EPILUMINESCENCE MICROSCOPY; ERYTHEMATOTELANGIECTATIC ROSACEA; FEMALE; GEL; HUMAN; IN VIVO STUDY; LOW LEVEL LASER THERAPY; OPTICAL COHERENCE TOMOGRAPHY; OPTICAL COHERENCE TOMOGRAPHY DEVICE; PAPULE; ROSACEA; SHORT COURSE THERAPY; SKIN EDEMA; SKIN STRUCTURE; TOPICAL TREATMENT; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; INTRADERMAL DRUG ADMINISTRATION; PATHOLOGY; PROCEDURES; SEVERITY OF ILLNESS INDEX;

ADMINISTRATION, CUTANEOUS; ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ADULT; FEMALE; GELS; HUMANS; QUINOXALINES; ROSACEA; SEVERITY OF ILLNESS INDEX; TOMOGRAPHY, OPTICAL COHERENCE; TREATMENT OUTCOME;

EID: 84904103498     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Ring HC, Mogensen M, Banzhaf C, Themstrup L, Jemec GB. Optical coherence tomography imaging of telangiectasias during intense pulsed light treatment: a potential tool for rapid outcome assessment. Arch Dermatol Res. 2013;305(4):299-303.
2. Koster PH, Bossuyt PM, van der Horst CM, Gijsbers GH, van Gemert MJ. Assessment of clinical outcome after flashlamp pumped pulsed dye laser treatment of portwine stains: a comprehensive questionnaire. Plast Reconst Surg. 1998;102(1):42-48. (Pubitemid 28303965)
3. Fowler J, Jarratt M, Moore A, et al. Once-daily topical brimonidine tartrate gel 0.5% is a novel treatment for moderate to severe facial erythema of rosacea: results of two multicentre, randomized and vehicle-controlled studies. Br J Dermatol. 2012;166(3):633-641.
4. Sattler E, Kästle R, Welzel J. Optical coherence tomography in dermatology. J Biomed Opt. 2013;18(6):061224.
5. Dalimier E, Salomon D. Full-field optical coherence tomography: a new technology for 3D high-resolution skin imaging. Dermatology. 2012;224(1):84-92.
6. Mogensen M, Nürnberg BM, Forman JL, Thomsen JB, Thrane L, Jemec GB. In vivo thickness measurement of basal cell carcinoma and actinic keratosis with optical coherence tomography and 20-MHz ultrasound. Br J Dermatol. 2009;160(5):1026-1033.
7. Huang D, Swanson EA, Lin CP et al. Optical coherence tomography. Science. 1991;254(5035):1178-1181. (Pubitemid 21917444)
8. Alawi SA, Kuck M, Wahrlich C, et al. Optical coherence tomography for pre-surgical margin assessment of non-melanoma skin cancer - a practical approach. Exp Dermatol. 2013;22(8):547-551.
9. Forsea AM, Carstea EM, Ghervase L, Giurcaneanu C, Pavelescu G. Clinical application of optical coherence tomography for the imaging of non-melanocytic cutaneous tumors: a pilot multi-modal study. J Med Life. 2010;3(4):381-389.
10. Aydin SZ, Castillo-Gallego C, Ash ZR, et al. Potential use of optical coherence tomography and high-frequency ultrasound for the assessment of nail disease in psoriasis and psoriatic arthritis. Dermatology. 2013;227(1):45-51.
11. Banzhaf CA, Themstrup L, Ring HC, Welzel J, Mogensen M, Jemec GB. In vivo imaging of sarcoptes scabiei infestation using optical coherence tomography. Case Rep Dermatol. 2013;5(2):156-162.
12. Wang KX, Meekings A, Fluhr JW, et al. Optical coherence tomography-based optimization of mohs micrographic surgery of Basal cell carcinoma: a pilot study. Dermatol Surg. 2013;39(4):627-633.
13. Mogensen M, Jemec GB. Diagnosis of nonmelanoma skin cancer/keratino-cyte carcinoma: a review of diagnostic accuracy of nonmelanoma skin cancer diagnostic tests and technologies. Dermatol Surg. 2007;33(10): 1158-1174. (Pubitemid 47508663)
14. Leitgeb R, Hitzenberger C, Fercher A. Performance of fourier domain vs. time domain optical coherence tomography. Opt Express. 2003;11(8):889-894.
15. Schuman JS, Hee MR, Arya AV et al. Optical coherence tomography: a new tool for glaucoma diagnosis. Curr Opin Ophthalmol. 1995;6(2):89-95.
16. Jambusaria-Pahlajani A, Schmults CD, Miller CJ, et al. Test characteristics of high-resolution ultrasound in the preoperative assessment of margins of basal cell and squamous cell carcinoma in patients undergoing Mohs micro-graphic surgery. Dermatol Surg. 2010;36(6):841-847
17. Marmur ES, Berkowitz EZ, Fuchs BS, Singer GK, Yoo JY. Use of high-frequency, high-resolution ultrasound before Mohs surgery. Dermatol Surg. 2010;36(6):841-847.
18. Mogensen M, Morsy HA, Thrane L, Jemec GB. Morphology and epidermal thickness of normal skin imaged by optical coherence tomography. Dermatology. 2008;217(1):14-20. (Pubitemid 351896562)
19. Diaconeasa A, Boda D, Neagu M, et al. The role of confocal microscopy in the dermato-oncology practice. J Med Life. 2011;4(1):63-74.
20. Rajadhyaksha M. Confocal microscopy of skin cancers: translational advances toward clinical utility. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:3231-3233.
21. Aydin SZ, Ash Z, Del Galdo F, et al. Optical coherence tomography: a new tool to assess nail disease in psoriasis? Dermatology. 2011;222(4):311-313.
22. Mogensen M, Thrane L, Joergensen TM, Andersen PE, Jemec GB. Optical coherence tomography for imaging of skin and skin diseases. Semin Cutan Med Surg. 2009;28(3): 196-202.
23. Welzel J, Bruhns M, Wolff HH. Optical coherence tomography in contact dermatitis and psoriasis. Arch Dermatol Res. 2003;295(2):50-55. (Pubitemid 36791723)
24. Miyachi Y. Potential antioxidant mechanism of action for metronidazole: implications for rosacea management. Adv Ther. 2001;18(6):237-243. (Pubitemid 34117279)
25. Aroni K, Tsagroni E, Kavantzas N, Patsouris E, Ioannidis E. A study of the pathogenesis of rosacea: how angiogenesis and mast cells may participate in a complex multifactorial process. Arch Dermatol Res. 2008;300(3):125-131.
26. Gomaa AH, Yaar M, Eyada MM, Bhawan J. Lymphangiogenesis and angiogenesis in non-phymatous rosacea. J Cutan Pathol. 2007;34(10):748-753. (Pubitemid 47459684)
27. Schwab VD, Sulk M, Seeliger S, et al. Neurovascular and neuroimmune aspects in the pathophysiology of rosacea. J Investig Dermatol Symp Proc. 2011;15(1):40-47
28. Wilkin JK. Rosacea. Pathophysiology and treatment. Arch Dermatol. 1994;130(3):359-362.
29. Del Rosso JQ. Management of facial erythema of rosacea: what is the role of topical α-adrenergic receptor agonist therapy? J Am Acad Dermatol. 2013;69(6 suppl 1):s44-s56.
30. Phillips KG, Wang Y, Levitz D, et al. Dermal reflectivity determined by optical coherence tomography is an indicator of epidermal hyperplasia and dermal edema within inflamed skin. J Biomed Opt. 2011;16(4):040503.