Mindfulness training modulates value signals in ventromedial prefrontal cortex through input from insular cortex

NeuroImage

Volumn 100, Issue , 2014, Pages 254-262

  Kirk, Ulrich ^a   Gu, Xiaosi ^b,c   Harvey, Ann H ^c   Fonagy, Peter ^b,d   Montague, P Read ^b,c  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c VIRGINIA TECH CARILION SCHOOL OF MEDICINE   (United States)

^d ANNA FREUD CENTRE   (United Kingdom)

Author keywords

FMRI; Insular cortex; Longitudinal design; Mindfulness training; Valuation; VmPFC

Indexed keywords

ACTIVE CONTROL TRAINING; ADULT; ART; ARTICLE; BEHAVIOR; BOLD SIGNAL; COGNITIVE BIAS; COHORT ANALYSIS; CONDITIONING; CONNECTOME; CONTROLLED STUDY; FEMALE; FRUIT JUICE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INSULA; INTEROCEPTIVE INPUT; LONGITUDINAL STUDY; MALE; MATHEMATICAL ANALYSIS; MINDFULNESS; MINDFULNESS TRAINING; POSTERIOR INSULA; PRIORITY JOURNAL; REWARD; SENSORY STIMULATION; TRAINING; VALUE SIGNALS; VENTROMEDIAL PREFRONTAL CORTEX; BRAIN CORTEX; BRAIN MAPPING; INTEROCEPTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; PREFRONTAL CORTEX; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; YOUNG ADULT;

ADULT; BRAIN MAPPING; CEREBRAL CORTEX; FEMALE; HUMANS; INTEROCEPTION; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MINDFULNESS; PREFRONTAL CORTEX; REWARD; YOUNG ADULT;

EID: 84904068227     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2014.06.035     Document Type: Article

References (42)

1. Allen M., Dietz M., Blair K.S., van Beek M., Rees G., Vestergaard-Poulsen P., Lutz A., Roepstorff A. Cognitive-affective neural plasticity following active-controlled mindfulness intervention. J. Neurosci. 2012, 32(44):15601-15610.
2. Ariely D., Loewenstein G., Prelec D. Tom Sawyer and the construction of value. J. Econ. Behav. Organ. 2006, 60:1-10.
3. Buchel C., Holmes A.P., Rees G., Friston K.J. Characterizing stimulus response functions using nonlinear regressors in parametric fMRI experiments. Neuroimage 1998, 8:140-148.
4. Cohen J.D., Perlstein W.M., Braver T.S., Nystrom L.E., Noll D.C., Jonides J., Smith E.E. Temporal dynamics of brain activation during a working memory task. Nature 1997, 386:604-608. (10).
5. Craig A.D. How do you feel? Interoception: the sense of the physiological condition of the body. Nat. Rev. Neurosci. 2002, 3:655-666.
6. Craig A.D. Interoception: the sense of the physiological condition of the body. Curr. Opin. Neurobiol. 2003, 13:500-505.
7. Craig A.D. How do you feel-now? The anterior insula and human awareness. Nat. Rev. Neurosci. 2009, 10:59-70.
8. Creswell J.D., Way B.M., Eisenberger N.I., Lieberman M.D. Neural correlates of dispositional mindfulness during affect labeling. Psychosom. Med. 2007, 69:560-565.
9. Critchley H.D., Wiens S., Rothstein P., Ohman A., Dolan R.J. Neural systems supporting interoceptive awareness. Nat. Neurosci. 2004, 7(2):189-195.
10. Damasio A. Self Comes to Mind: Constructing the Conscious Brain 2010, Pantheon Books, New York, NY.
11. De Araujo I.E., Rolls E.T., Velazco M.I., Margot C., Cayeux I. Cognitive modulation of olfactory processing. Neuron 2005, 46:671-679.
12. Deichmann R., Gottfried J.A., Hutton C., Turner R. Optimized EPI for fMRI studies of the orbitofrontal cortex. Neuroimage 2003, 19:430-441.
13. Falk E.B. Mindfulness and the neuroscience of influence. The Wiley Handbook of Mindfulness 2014, John Wiley & Sons Ltd. C.T. Christelle, Ngnoumen, E.J. Langer (Eds.).
14. Farb N.A., Segal Z.V., Mayberg H., Bean J., McKeon D., Fatima Z., Anderson A.K. Attending to the present: mindfulness meditation reveals distinct neural modes of self-reference. Soc. Cogn. Affect. Neurosci. 2007, 2(4):313-322.
15. Farb N.A., Anderson A.K., Mayberg H., Bean J., McKeon D., Segal Z.V. Minding one's emotions: mindfulness training alters the neural expression of sadness. Emotion 2010, 10:25-33.
16. Farb N.A., Segal Z.V., Anderson A.K. Mindfulness meditation training alters cortical representations of interoceptive attention. Soc. Cogn. Affect. Neurosci. 2013, 8(1):15-26. (Jan).
17. Friston K.J., Williams R., Howard R.S., Frackowiak R.S.J., Turner R. Movement-related effects in fMRI time-series. Magn. Reson. Med. 1996, 35:346-355.
18. Friston K.J., Buchel C., Fink G.R., Morris J., Rolls E., Dolan R.J. Psychophysiological and modulatory interactions in neuroimaging. Neuroimage 1997, 6:218-229.
19. Friston K.J., Fletcher P., Joseph O., Holmes A., Rugg M.D., Turner R. Event-related fMRI: characterizing differential responses. Neuroimage 1998, 7:30-40.
20. Fuster J.M., Alexander G.E. Neuron activity related to short-term memory. Science 1971, 13(173):652-654.
21. Glaser D., Friston K.J. Variance components. Human Brain Function 2004, Elsevier Academic Press. R.S.J. Frackowiak, K.J. Friston, C.D. Frith, R.J. Dolan, C.J. Price, S. Zeki (Eds.).
22. Gu X., Hof P.R., Friston K.J., Fan J. Anterior insular cortex and emotional awareness. J. Comp. Neurol. 2013, 521(15):3371-3388.
23. Hampton A.N., Bossaerts P., O'Doherty J.P. The role of the ventromedial prefrontal cortex in abstract state-based inference during decision making in humans. J. Neurosci. 2006, 32:8360-8367.
24. Harvey A., Kirk U., Denfield G., Montague P.R. Monetary favors and their influence on neural responses and revealed preference. J. Neurosci. 2010, 30:9597-9602.
25. Holzel B.K., Ott U., Hempel H., Hackl A., Wolf K., Stark R. Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators. Neurosci. Lett. 2007, 421:16-21.
26. Kabat-Zinn J. Full Catastrophe Living. Using the Wisdom of Your Body and Mind to Face Stress, Pain and Illness 1990, Random House.
27. Kirk U., Skov M., Hulme O., Christensen M.S., Zeki S. Modulation of aesthetic value by semantic context: an fMRI study. Neuroimage 2009, 44:1125-1132.
28. Kirk U., Harvey A., Montague P.R. Domain expertise insulates against judgment bias by monetary favors through a modulation of ventromedial prefrontal cortex. Proc. Natl. Acad. Sci. U. S. A. 2011, 108(25):10332-10336. (21).
29. Kirk U., Downar J., Montague P.R. Interoception drives increased rational decision-making in meditators playing the ultimatum game. Front. Neurosci. 2011, 5:49. (Apr 18).
30. Lebreton M., Jorge S., Michel V., Thirion B., Pessiglione M. An automatic valuation system in the human brain: evidence from functional neuroimaging. Neuron 2009, 63:431-439.
31. Lutz A., Slagter H.A., Dunne J.D., Davidson R.J. Attention regulation and monitoring in meditation. Trends Cogn. Sci. 2008, 12(4):163-169.
32. McClure S.M., Li J., Tomlin D., Cypert K.S., Montague L.M., Montague P.R. Neural correlates of behavioral preference for culturally familiar drinks. Neuron 2004, 44:379-387.
33. Monin B. The warm glow heuristic: when liking leads to familiarity. J. Pers. Soc. Psychol. 2003, 85(6):1035-1048. (Dec).
34. Ogawa S., Lee T.M., Kay A.R., Tank D.W. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:9868-9872.
35. Padoa-Schioppa C., Assad J.A. Neurons in the orbitofrontal cortex encode economic value. Nature 2006, 441:223-226.
36. Philiastides M.G., Biele G., Heekeren H.R. A mechanistic account of value computation in the human brain. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:9430-9435.
37. Plassmann H., O'Doherty J., Shiv B., Rangel A. Marketing actions can modulate neural representations of experienced pleasantness. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:1050-1054.
38. Seth A.K., Suzuki K., Critchley H.D. An interoceptive predictive coding model of conscious presence. Front. Psychol. 2011, 2:395.
39. Shapiro S.L., Carlson L.E., Astin J.A., Freedman B. Mechanisms of mindfulness. J. Clin. Psychol. 2006, 62:373-386.
40. Tang Y.Y., Ma Y., Fan Y., Feng H., Wang J., Feng S., Lu Q., Hu B., Lin Y., Li J., Zhang Y., Wang Y., Zhou L., Fan M. Central and autonomic nervous system interaction is altered by short-term meditation. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(22):8865-8870. (2).
41. Worsley K.J., Marrett S., Neelin P., Vandal A.C., Friston K. A unified statistical approach for determining significant signals in images of cerebral activation. Hum. Brain Mapp. 1996, 4:58-73.
42. Zeidan F., Martucci K.T., Kraft R.A., Gordon N.S., McHaffie J.G., Coghill R.C. Brain mechanisms supporting the modulation of pain by mindfulness meditation. J. Neurosci. 2011, 31(14):5540-5548. (Apr 6).