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Volumn 24, Issue 2, 2014, Pages 258-264

Remission in patients with active rheumatoid arthritis by tocilizumab treatment in routine clinical practice: Results from 3 years of prospectively registered data

(22)  Nakashima, Yasuharu a   Kondo, Masakazu b   Fukuda, Takaaki c   Harada, Hiroshi d   Horiuchi, Takahiko e   Ishinishi, Takashi f   Jojima, Hiroshi g   Kuroda, Koji h   Miyahara, Hisaaki i   Maekawa, Masayuki j   Nishizaka, Hiroaki k   Nagamine, Ryuji l   Nakashima, Hitoshi m   Otsuka, Takeshi n   Shono, Eisuke o   Suematsu, Eiichi i   Shimauchi, Takashi p   Tsuru, Tomomi q   Wada, Ken r   Yoshizawa, Shigeru s   more..


Author keywords

Registry; Remission; Rheumatoid arthritis; Routine clinical practice; Tocilizumab

Indexed keywords

ADALIMUMAB; C REACTIVE PROTEIN; ETANERCEPT; INFLIXIMAB; METHOTREXATE; PREDNISOLONE; TOCILIZUMAB;

EID: 84904057081     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.3109/14397595.2013.854069     Document Type: Article
Times cited : (19)

References (25)
  • 1
    • 77953694972 scopus 로고    scopus 로고
    • Current evidence for the management of rheumatoid arthritis with biological disease-modifying anti-rheumatic drugs: A systematic literature review informing the eular recommendations for the management of ra
    • Nam JL , Winthrop KL , van Vollenhoven RF , Pavelka K , Valesini G , Hensor EM , et al. Current evidence for the management of rheumatoid arthritis with biological disease-modifying anti-rheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA. Ann Rheum Dis. 2010 ; 69 : 976-86.
    • (2010) Ann Rheum Dis. , vol.69 , pp. 976-986
    • Nam, J.L.1    Winthrop, K.L.2    Van Vollenhoven, R.F.3    Pavelka, K.4    Valesini, G.5    Hensor, E.M.6
  • 3
    • 84860895505 scopus 로고    scopus 로고
    • A tight control treatment strategy aiming for remission in early rheumatoid arthritis is more effective than usual care treatment in daily clinical practice: A study of two cohorts in the dutch rheumatoid arthritis monitoring registry
    • Schipper L G, Vermeer M , Kuper H H, Hoekstra M O, Haagsma C J, Den Broeder AA , et al. A tight control treatment strategy aiming for remission in early rheumatoid arthritis is more effective than usual care treatment in daily clinical practice: a study of two cohorts in the Dutch Rheumatoid Arthritis Monitoring registry. Ann Rheum Dis. 2012 ; 71 : 845-50.
    • (2012) Ann Rheum Dis. , vol.71 , pp. 845-850
    • Schipper, L.G.1    Vermeer, M.2    Kuper, H.H.3    Hoekstra, M.O.4    Haagsma, C.J.5    Den Broeder, A.A.6
  • 4
    • 79957630321 scopus 로고    scopus 로고
    • Efficacy of abatacept and tocilizumab in patients with rheumatoid arthritis treated in clinical practice: Results from the nationwide danish danbio registry
    • Leffers HC , Ostergaard M , Glintborg B , Krogh NS , Foged H , Tarp U , et al. Efficacy of abatacept and tocilizumab in patients with rheumatoid arthritis treated in clinical practice: results from the nationwide Danish DANBIO registry. Ann Rheum Dis. 2011 ; 70 : 1216-22.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 1216-1222
    • Leffers, H.C.1    Ostergaard, M.2    Glintborg, B.3    Krogh, N.S.4    Foged, H.5    Tarp, U.6
  • 5
    • 79953319576 scopus 로고    scopus 로고
    • Effectiveness and safety of the interleukin 6-receptor antagonist tocilizumab after 4 and 24 weeks in patients with active rheumatoid arthritis: The first phase iiib real-life study (tamara
    • Burmester GR , Feist E , Kellner H , Braun J , Iking-Konert C , Rubbert-Roth A , et al. Effectiveness and safety of the interleukin 6-receptor antagonist tocilizumab after 4 and 24 weeks in patients with active rheumatoid arthritis: the first phase IIIb real-life study (TAMARA). Ann Rheum Dis. 2011 ; 70 : 755-9.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 755-759
    • Burmester, G.R.1    Feist, E.2    Kellner, H.3    Braun, J.4    Iking-Konert, C.5    Rubbert-Roth, A.6
  • 6
    • 70349402169 scopus 로고    scopus 로고
    • Long-term safety and efficacy of tocilizumab, an anti-il-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the stream study): Evidence of safety and efficacy in a 5-year extension study
    • Nishimoto N , Miyasaka N , Yamamoto K , Kawai S , Takeuchi T , Azuma J.Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study. Ann Rheum Dis. 2009 ; 68 : 1580-4.
    • (2009) Ann Rheum Dis. , vol.68 , pp. 1580-1584
    • Nishimoto, N.1    Miyasaka, N.2    Yamamoto, K.3    Kawai, S.4    Takeuchi, T.5    Azuma, J.6
  • 7
    • 40749114497 scopus 로고    scopus 로고
    • Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (option study): A double-blind, placebo-controlled, randomised trial
    • Smolen J S, Beaulieu A , Rubbert-Roth A , Ramos-Remus C , Rovensky J , Alecock E , et al. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet. 2008 ; 371 : 987-97.
    • (2008) Lancet. , vol.371 , pp. 987-997
    • Smolen, J.S.1    Beaulieu, A.2    Rubbert-Roth, A.3    Ramos-Remus, C.4    Rovensky, J.5    Alecock, E.6
  • 8
    • 54949150604 scopus 로고    scopus 로고
    • Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: The tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study
    • Genovese MC , McKay JD , Nasonov EL , Mysler EF , de Silva NA , Alecock E , et al. Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: the tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study. Arthritis Rheum. 2008 ; 58 : 2968-80.
    • (2008) Arthritis Rheum. , vol.58 , pp. 2968-2980
    • Genovese, M.C.1    McKay, J.D.2    Nasonov, E.L.3    Mysler, E.F.4    De Silva, N.A.5    Alecock, E.6
  • 9
    • 73449118587 scopus 로고    scopus 로고
    • Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: The ambition study
    • Jones G , Sebba A , Gu J , Lowenstein M B, Calvo A , Gomez-Reino J J, et al. Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study. Ann Rheum Dis. 2010 ; 69 : 88-96.
    • (2010) Ann Rheum Dis. , vol.69 , pp. 88-96
    • Jones, G.1    Sebba, A.2    Gu, J.3    Lowenstein, M.B.4    Calvo, A.5    Gomez-Reino, J.J.6
  • 10
    • 52149099504 scopus 로고    scopus 로고
    • Il-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: Results from a 24-week multicentre randomized placebo-controlled trial
    • Amery P , Keystone E , Tony H P, Cantagrel A , Van Vollenhoven R , Sanchez A, et al. IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomized placebo-controlled trial. Ann Rheum Dis. 2008 ; 67 : 1516-23.
    • (2008) Ann Rheum Dis. , vol.67 , pp. 1516-1523
    • Amery, P.1    Keystone, E.2    Tony, H.P.3    Cantagrel, A.4    Van Vollenhoven, R.5    Sanchez, A.6
  • 11
    • 79953680176 scopus 로고    scopus 로고
    • Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: Results from the double-blind treatment phase of a randomized placebocontrolled trial of tocilizumab safety and prevention of structural joint damage at one year
    • Kremer JM , Blanco R , Brzosko M , Burgos-Vargas R , Halland AM , Vernon E , et al. Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebocontrolled trial of tocilizumab safety and prevention of structural joint damage at one year. Arthritis Rheum. 2011 ; 63 : 609-21.
    • (2011) Arthritis Rheum. , vol.63 , pp. 609-621
    • Kremer, J.M.1    Blanco, R.2    Brzosko, M.3    Burgos-Vargas, R.4    Halland, A.M.5    Vernon, E.6
  • 12
    • 74849094402 scopus 로고    scopus 로고
    • Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: Results from eight years of surveillance of clinical practice in the nationwide danish danbio registry
    • Hetland M L, Christensen I J, Tarp U , Dreyer L , Hansen A , Hansen IT , et al. Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry. Arthritis Rheum. 2010 ; 62 : 22-32.
    • (2010) Arthritis Rheum. , vol.62 , pp. 22-32
    • Hetland, M.L.1    Christensen, I.J.2    Tarp, U.3    Dreyer, L.4    Hansen, A.5    Hansen, I.T.6
  • 13
    • 84862563304 scopus 로고    scopus 로고
    • A comparative effectiveness study of adalimumab, etanercept and infliximab in biologically naive and switched rheumatoid arthritis patients: Results from the us corrona registry
    • Greenberg J D, Reed G , Decktor D , Harrold L , Furst D , Gibofsky A , Et al. A comparative effectiveness study of adalimumab, etanercept and infliximab in biologically naive and switched rheumatoid arthritis patients: results from the US CORRONA registry. A nn Rheum Dis. 2 012; 7 1: 1 134-42.
    • (2012) Ann Rheum Dis. , vol.71 , Issue.1 , pp. 134-142
    • Greenberg, J.D.1    Reed, G.2    Decktor, D.3    Harrold, L.4    Furst, D.5    Gibofsky, A.6
  • 14
    • 80053141949 scopus 로고    scopus 로고
    • Clinical, radiographic and functional effectiveness of tocilizumab for rheumatoid arthritis patients - Reaction 52-week study
    • Takeuchi T , Tanaka Y , Amano K , Hoshi D , Nawata M , Nagasawa H , et al. Clinical, radiographic and functional effectiveness of tocilizumab for rheumatoid arthritis patients - REACTION 52-week study. Rheumatology (Oxford). 2011 ; 50 : 1908-15.
    • (2011) Rheumatology (Oxford , vol.50 , pp. 1908-1915
    • Takeuchi, T.1    Tanaka, Y.2    Amano, K.3    Hoshi, D.4    Nawata, M.5    Nagasawa, H.6
  • 15
    • 78349285989 scopus 로고    scopus 로고
    • Clinical evaluation of tocilizumab for patients with active rheumatoid arthritis refractory to anti-tnf biologics: Tocilizumab in combination with methotrexate
    • Nakashima Y , Kondo M , Harada H , Horiuchi T , Ishinishi T , Jojima H , et al. Clinical evaluation of tocilizumab for patients with active rheumatoid arthritis refractory to anti-TNF biologics: tocilizumab in combination with methotrexate. Mod Rheumatol. 2010 ; 20 : 343-52.
    • (2010) Mod Rheumatol. , vol.20 , pp. 343-352
    • Nakashima, Y.1    Kondo, M.2    Harada, H.3    Horiuchi, T.4    Ishinishi, T.5    Jojima, H.6
  • 17
    • 79951506884 scopus 로고    scopus 로고
    • American college of rheumatology/european league against rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials
    • Felson DT , Smolen JS , Wells G , Zhang B , Tuyl LH , Funovits J , et al. American College of Rheumatology/European League against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials. Ann Rheum Dis. 2011 ; 70 : 404-13.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 404-413
    • Felson, D.T.1    Smolen, J.S.2    Wells, G.3    Zhang, B.4    Tuyl, L.H.5    Funovits, J.6
  • 18
    • 0029797663 scopus 로고    scopus 로고
    • Development and validation of response criteria in rheumatoid arthritis: Steps towards an international consensus on prognostic markers
    • van Riel PL , van Gestel AM , van de Putte LB. Development and validation of response criteria in rheumatoid arthritis: steps towards an international consensus on prognostic markers. Br J Rheumatol. 1996 ; 35 (Suppl 2) : 4-7.
    • (1996) Br J Rheumatol. , vol.35 , Issue.SUPPL. 2 , pp. 4-7
    • Van Riel, P.L.1    Van Gestel, A.M.2    Van De Putte, L.B.3
  • 19
    • 78650764821 scopus 로고    scopus 로고
    • Interleukin-6 receptor inhibition with tocilizumab and attainment of disease remission in rheumatoid arthritis: The role of acute-phase reactants
    • Smolen J S, Aletaha D.Interleukin-6 receptor inhibition with tocilizumab and attainment of disease remission in rheumatoid arthritis: the role of acute-phase reactants. Arthritis Rheum. 2011 ; 63 : 43-52.
    • (2011) Arthritis Rheum. , vol.63 , pp. 43-52
    • Smolen, J.S.1    Aletaha, D.2
  • 20
    • 80053562078 scopus 로고    scopus 로고
    • Performance of the new 2011 acr/eular remission criteria with tocilizumab using the phase iiib study tamara as an example and their comparison with traditional remission criteria
    • Iking-Konert C , Aringer M , W ollenhaupt J , Mosch T , Tuerk S , Feist E , et al. Performance of the new 2011 ACR/EULAR remission criteria with tocilizumab using the phase IIIb study TAMARA as an example and their comparison with traditional remission criteria. Ann Rheum Dis. 2011 ; 70 : 1986-90.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 1986-1990
    • Iking-Konert, C.1    Aringer, M.2    Wollenhaupt, J.3    Mosch, T.4    Tuerk, S.5    Feist, E.6
  • 21
    • 83255162593 scopus 로고    scopus 로고
    • Disease activity score 28 may overestimate the remission induction of rheumatoid arthritis patients treated with tocilizumab: Comparison with the remission by the clinical disease activity index
    • Kawashiri S Y, Kawakami A , Iwamoto N , Fujikawa K , Aramaki T , Tamai M , et al. Disease activity score 28 may overestimate the remission induction of rheumatoid arthritis patients treated with tocilizumab: comparison with the remission by the clinical disease activity index. Mod Rheumatol. 2011 ; 21 : 365-9.
    • (2011) Mod Rheumatol. , vol.21 , pp. 365-369
    • Kawashiri, S.Y.1    Kawakami, A.2    Iwamoto, N.3    Fujikawa, K.4    Aramaki, T.5    Tamai, M.6
  • 22
    • 35348822055 scopus 로고    scopus 로고
    • Disease activity early in the course of treatment predicts response to therapy after one year in rheumatoid arthritis patients
    • Aletaha D , Funovits J , Keystone EC , Smolen JS. Disease activity early in the course of treatment predicts response to therapy after one year in rheumatoid arthritis patients. Arthritis Rheum. 2007 ; 56 (10) : 3226-35.
    • (2007) Arthritis Rheum. , vol.56 , Issue.10 , pp. 3226-3235
    • Aletaha, D.1    Funovits, J.2    Keystone, E.C.3    Smolen, J.S.4
  • 23
    • 77956646068 scopus 로고    scopus 로고
    • Safety and efficacy profiles of tocilizumab monotherapy in japanese patients with rheumatoid arthritis: Meta-Analysis of six initial trials and five long-term extensions
    • Nishimoto N , Ito K , Takagi N.Safety and efficacy profiles of tocilizumab monotherapy in Japanese patients with rheumatoid arthritis: meta-Analysis of six initial trials and five long-term extensions. Mod Rheumatol. 2010 ; 20 : 222-32.
    • (2010) Mod Rheumatol. , vol.20 , pp. 222-232
    • Nishimoto, N.1    Ito, K.2    Takagi, N.3
  • 24
    • 84867405325 scopus 로고    scopus 로고
    • Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules
    • Sakai R , Tanaka M , Nanki T , Watanabe K , Yamazaki H , Koike R , et al. Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules. Ann Rheum Dis. 2012 ; 71 : 1820-6.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1820-1826
    • Sakai, R.1    Tanaka, M.2    Nanki, T.3    Watanabe, K.4    Yamazaki, H.5    Koike, R.6
  • 25
    • 79952013541 scopus 로고    scopus 로고
    • Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: A systematic literature review and metaanalysis of randomized controlled trials
    • Campbell L , Chen C , Bhagat S S, Parker R A, Ö s tö r A J.Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and metaanalysis of randomized controlled trials. Rheumatology (Oxford). 2011 ; 50 : 552-62.
    • (2011) Rheumatology (Oxford , vol.50 , pp. 552-562
    • Campbell, L.1    Chen, C.2    Bhagat, S.S.3    Parker, R.A.4    Östör, A.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.