Reduced telomere length is not associated with early signs of vascular aging in young men born after intrauterine growth restriction: A paradox?

Journal of Hypertension

Volumn 32, Issue 8, 2014, Pages 1613-1620

  Laganović, Mario ^a   Bendix, Laila ^b   Rubelj, Ivica ^c   Kirhmajer, Majda Vrkić ^d   Slade, Neda ^e   Lela, Ivana Vuković ^a   Premužić, Vedran ^a   Nilsson, Peter M ^f   Jelaković, Bojan ^a  

^a KBC Zagreb   (Croatia)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c Department for Molecular Biology Ruper Bo kovi Institute   (Croatia)

^d Department of Virology   (United States)

^e RUDER BO KOVI INSTITUTE   (Croatia)

^f LUND UNIVERSITY   (Sweden)

Author keywords

cardiovascular diseases; fetal growth retardation; genetics; telomeres

Indexed keywords

ADULT; ADULTHOOD; AGING; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR RISK; CLINICAL EXAMINATION; CONTROLLED STUDY; GESTATIONAL AGE; HEART RATE; HUMAN; HUMAN EXPERIMENT; INTRAUTERINE GROWTH RETARDATION; LABORATORY TEST; LEUKOCYTE; LIFESTYLE; MALE; MEDICAL RECORD REVIEW; NORMAL HUMAN; PRIORITY JOURNAL; PULSE PRESSURE; QUESTIONNAIRE; SMALL FOR DATE INFANT; TELOMERE; TELOMERE LENGTH; YOUNG ADULT; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; CELL AGING; CROSS-SECTIONAL STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; STATISTICAL MODEL;

ADULT; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; CAROTID INTIMA-MEDIA THICKNESS; CELL AGING; CROSS-SECTIONAL STUDIES; FETAL GROWTH RETARDATION; HUMANS; INFANT, SMALL FOR GESTATIONAL AGE; LINEAR MODELS; MALE; TELOMERE; YOUNG ADULT;

EID: 84904044820     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000217     Document Type: Article

References (42)

1. Chan SR, Blackburn EH. Telomeres and telomerase. Philos Trans R Soc Lond B Biol Sci 2004; 359:109-121. (Pubitemid 38106454)
2. Eisenberg DT. An evolutionary review of human telomere biology: The trifty telomere hypothesis and notes on potential adaptive paternal effects. Am J Human Biol 2011; 23:149-167.
3. Demissie S, Levy D, Benjamin EJ, Cupples LA, Gardner JP, Herbert A, et al. Insulin resistance, oxidative stress, hypertension ad leukocyte telomere length in men from the Framingham Heart Study. Aging Cell 2006; 5:325-330. (Pubitemid 44103248)
4. Aviv A. Telomeres and human ageing: facts and fibs. Sci Aging Knowledge Environ 2004; 2004:43.
5. Minamino T, Komuro I. Role of telomere in endothelial dysfunction in atherosclerosis. Curr Opin Lipidol 2002; 13:537-543. (Pubitemid 35231934)
6. Brouilette S, Singh RK, Thompson JR, Goodal AH, Samani NJ. White cell telomere length and risk of premature myocardial infarction. Atherosclerosis Thromb Vasc Biol 2003; 23:842-846. (Pubitemid 36566175)
7. Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 2003; 361:393-395. (Pubitemid 36164975)
8. Benetos A, Lajemi KOM, Thomas F, Skurnick J, Labat C, Bean K, Aviv A. Telomere length as an indicator of biological ageing. The gender effect and relation with pulse pressure and pulse wave velocity. Hypertension 2001; 37 (part 2):381-385. (Pubitemid 32198997)
9. Nilsson PM, Dahlman D, Roos G, Nordfjall K, Melander O. Telomere attrition over fifteen years is associated with clinical markers of cardiovascular ageing in middle-aged subjects: The Malmo Diet and Cancer Study (abstract). J Hypertens 2011; 29:e475.
10. Kuznetsova T, Codd V, Brouilette S, Thijs L, González A, Jin Y, et al. Association between left ventricular mass and telomere length in a population study. Am J Epidemiol 2010; 172:440-450.
11. Nilsson PM, Tufvesson H, Leosdottir M, Melander O. Telomeres and cardiovascular disease risk: An update 2013. Translat Res 2013; 162:371-380.
12. Barker DJ, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS. Fetal nutrition and cardiovascular disease in adult life. Lancet 1993; 341:938-941. (Pubitemid 23109122)
13. Rueda-Clausen C, Morton JS, Davidge ST. Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood. Cardiovasc Res 2009; 81:713-722.
14. Ojeda NB, Grigore D, Alexander BT. Intrauterine growth restriction: fetal programming of hypertension and kidney disease. Adv Chronic Kidney Dis 2008; 15:101-106. (Pubitemid 351335411)
15. Stocker CJ, Arch JR, Cawthorne MA. Fetal origins of insulin resistance and obesity. Proc Nutr Soc 2005; 64:143-151. (Pubitemid 40813536)
16. Barker DJ. Intrauterine programming of adult disease. Mol Med Today 1995; 1:418-423
17. Cheung YF, Wong KY, Lam BC, Tsoi NS. Relation of arterial stiffness with gestational age and birth weight. Arch Dis Child 2004; 89:217-221. (Pubitemid 38325809)
18. Brodszki J, Lanne T, Marshal K, Ley D. Impaired vascular growth in late adolescence after intrauterine growth restriction. Circulation 2005; 111:2623-2628. (Pubitemid 40740862)
19. Miles KL, Donnell BJ, Maki-Petaja KM, Cockroft JR, Wilkinson IB, McIniery CM, on behalf of ENIGMA study investigators. The impact of birth weight on blood pressure and arterial stiffness in later life: The ENIGMA study. J Hypertens 2011; 29:2324-2331.
20. Lurbe E, Torro MI, Carvajal E, Alvarez V, Redon J. Birth weight impacts on wave reflections in children and adolescents. Hypertension 2003; 41:646-650. (Pubitemid 36314568)
21. Bonamy AK, Norma M, Kajiser M. Being born too small, too early or both: does it matter for risk of hypertension in the elderly. Am J Hypertens 2008; 21:1107-1110.
22. Drazancić A. Nutritivna i respiracijska funkcija posteljice i rast fetusa. U:Drazancić A i suradnici Porodnistvo. Zagreb Skolska knjiga 1999;120-133.
23. Kanters SD, Algra A, van Leeuwen MS, Banga JD. Reproducibility of in vivo carotid intima-media thicknessmeasurements. Stroke 1997; 28:665-671. (Pubitemid 27118395)
24. Cawthon RM. Telomere measurement by quantitative PCR. Nucl Acids Res 2002; 30:e47.
25. Cawthon RM. Telomere length measurement by novel monochrome multiplex quantitative PCR method. Nucl Acids Res 2009; 37:e21.
26. Leon DA, Johansson M, Rasmussen F. Gestational age and growth rate of fetal mass are inversely associated with systolic blood pressure in young adults: An epidemiologic study of 165,136 Swedish men aged 18 years. Am J Epidemiol 2000; 152:597-604.
27. Vos LE, Oren A, Uiterwaal C, Gorrisen WHM, Grobbee DE, Bots ML. Adolescent blood pressure tracking into young adulthood are related to subclinical atherosclerosis: The atherosclerosis risk in young adults (ARYA) study. Am J Hypertens 2003; 16:549-555. (Pubitemid 36829704)
28. Aviv A. Genetics of leukocyte telomere length and its role in atherosclerosis. Mutat Res 2012; 730:68-74.
29. Benetos A, Gardner JP, Zureik GM, Labat C, Xiaobin L, Adamopoulos C, et al. Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects. Hypertension 2004; 43:182-185. (Pubitemid 38174171)
30. Friedrich U, Schwab M, Griese EU, Fritz P, Klotz U. Telomeres in neonates: new insights in fetal hematopoiesis. Pediatr Res 2001; 49: 252-256. (Pubitemid 32119223)
31. Akkad A,HastingsR, Konje JC, Bell SC, Thurston H,Williams B. Telomere length in small-for-gestational-age babies. BJOG 2006; 113:318-323.
32. Davy P, Nagata M, Bullard P, Fogelson NS, Allsopp R. Fetal growth restriction is associated with accelerated telomere shortening and increased expression of cell senescence markers in the placenta. Placenta 2009; 30:539-542.
33. Entringer S, Epel ES, Kumsta R, Lin J, Hellhammer DH, Blackburn EH, et al. Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood. Proc Natl Acad Sci U S A 2011; 108:E513-E518.
34. Raqib R, Alam DS, Sarker P, Ahmad SM, Ara G, Yunus M, et al. Low birth weight is associated with altered immune function in rural Bangladeshi children: A birth cohort study. Am J Clin Nutr 2007; 85:845-852. (Pubitemid 46393518)
35. Needham BL, Fernandez JR, Lin J, Epel ES, Blackburn EH. Socioeconomic status and cell aging in children. Soc Sci Med 2012; 74:1948-1951.
36. Shiels PG, McGlynn LM, MacIntyre A, Johnson PC, Batty GD, Burns H, et al. Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort. PLoS One 2011; 6:e22521.
37. Milner RDG, Gluckman PD. Regulation of intrauterine growth. In: Gluckman PD, Heymann MA, editors. Pediatrics and perinatology: The scientific basis. London: Arnold; 1996. pp. 284-289.
38. Cross JA, Temple RC, Hughes JC, Dozio NC, Brennan C, Stanley K, et al. Cord blood telomere length, telomerase activity and inflammatory markers in pregnancies in women with diabetes or gestational diabetes. Diabet Med 2010; 27:1264-1270.
39. Chernausek SD. Update: consequences of abnormal fetal growth. J Clin Endocrinol Metab 2012; 97:689-695.
40. Arnoult N, Van Beneden A, Decottignies A. Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1a. Nat Struct Mol Biol 2012; 19:948-956.
41. Fyhrquist F, Saijonmaa O. Telomere length and cardiovascular aging. Ann Med 2012; 44 (Suppl 1):S138-S142.
42. Spyridopoulos I, Hoffmann J, Aicher A, Brümmendorf TH, Doerr HW, Zeiher AM, et al. Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity. Circulation 2009; 120:1364-1372.