Modeling gene-environment interactions in oral cavity and esophageal cancers demonstrates a role for the p53 R72P polymorphism in modulating susceptibility

Molecular Carcinogenesis

Volumn 53, Issue 8, 2014, Pages 648-658

  Sarkar, Jayanta ^a   Dominguez, Emily ^a,b   Li, Guojun ^c   Kusewitt, Donna F ^a,b   Johnson, David G ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

4NQO; HPV16; P53 polymorphism; Squamous cell carcinoma

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; PROTEIN E6; PROTEIN E7; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CODON; CONTROLLED STUDY; ESOPHAGUS CANCER; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN PAPILLOMAVIRUS TYPE 16; MOUSE; MOUTH CANCER; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

HUMAN PAPILLOMAVIRUS;

4NQO; HPV16; P53 POLYMORPHISM; SQUAMOUS CELL CARCINOMA;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; BLOTTING, WESTERN; CARCINOGENS; CELLS, CULTURED; DNA, VIRAL; ESOPHAGEAL NEOPLASMS; FEMALE; GENE-ENVIRONMENT INTERACTION; HUMANS; IMMUNOENZYME TECHNIQUES; INFLAMMATION; KERATINOCYTES; MICE; MICE, TRANSGENIC; MOUTH NEOPLASMS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS E7 PROTEINS; PAPILLOMAVIRUS INFECTIONS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84904036590     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22019     Document Type: Article

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