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Volumn 53, Issue 8, 2014, Pages 635-647

Loss of T-cadherin (CDH-13) regulates AKT signaling and desensitizes cells to apoptosis in melanoma

Author keywords

AKT; AP 1; Cell adhesion; CREB; FoxO3a

Indexed keywords

CADHERIN; CLUSTERIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FAS ANTIBODY; GLYCOSYLPHOSPHATIDYLINOSITOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN KINASE B; T CADHERIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

EID: 84904024562     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22018     Document Type: Article
Times cited : (22)

References (37)
  • 1
    • 65549109811 scopus 로고    scopus 로고
    • H-cadherin expression reduces invasion of malignant melanoma
    • Kuphal S, Martyn AC, Pedley J, et al. H-cadherin expression reduces invasion of malignant melanoma. Pigment Cell Melanoma Res 2009; 22:296-306.
    • (2009) Pigment Cell Melanoma Res , vol.22 , pp. 296-306
    • Kuphal, S.1    Martyn, A.C.2    Pedley, J.3
  • 2
    • 0028334894 scopus 로고
    • E-cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro
    • Tang A, Eller MS, Hara M, Yaar M, Hirohashi S, Gilchrest BA. E-cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro. J Cell Sci 1994; 107:983-992.
    • (1994) J Cell Sci , vol.107 , pp. 983-992
    • Tang, A.1    Eller, M.S.2    Hara, M.3    Yaar, M.4    Hirohashi, S.5    Gilchrest, B.A.6
  • 3
    • 0033571307 scopus 로고    scopus 로고
    • Regulation of E- and P-cadherin expression correlated with melanocyte migration and diversification
    • Nishimura EK, Yoshida H, Kunisada T, Nishikawa SI. Regulation of E- and P-cadherin expression correlated with melanocyte migration and diversification. Dev Biol 1999; 215:155-166.
    • (1999) Dev Biol , vol.215 , pp. 155-166
    • Nishimura, E.K.1    Yoshida, H.2    Kunisada, T.3    Nishikawa, S.I.4
  • 5
    • 1942424829 scopus 로고    scopus 로고
    • CDH13 promoter region is specifically methylated in poorly differentiated colorectal cancer
    • Hibi K, Nakayama H, Kodera Y, Ito K, Akiyama S, Nakao A. CDH13 promoter region is specifically methylated in poorly differentiated colorectal cancer. Br J Cancer 2004; 90:1030-1033.
    • (2004) Br J Cancer , vol.90 , pp. 1030-1033
    • Hibi, K.1    Nakayama, H.2    Kodera, Y.3    Ito, K.4    Akiyama, S.5    Nakao, A.6
  • 6
    • 0033208647 scopus 로고    scopus 로고
    • Involvement of H-cadherin (CDH13) on 16q in the region of frequent deletion in ovarian cancer
    • Kawakami M, Staub J, Cliby W, Hartmann L, Smith DI, Shridhar V. Involvement of H-cadherin (CDH13) on 16q in the region of frequent deletion in ovarian cancer. Int J Oncol 1999; 15:715-720.
    • (1999) Int J Oncol , vol.15 , pp. 715-720
    • Kawakami, M.1    Staub, J.2    Cliby, W.3    Hartmann, L.4    Smith, D.I.5    Shridhar, V.6
  • 7
    • 27244444605 scopus 로고    scopus 로고
    • Aberrant methylation of H-cadherin (CDH13) promoter is associated with tumor progression in primary nonsmall cell lung carcinoma
    • Kim JS, Han J, Shim YM, Park J, Kim DH. Aberrant methylation of H-cadherin (CDH13) promoter is associated with tumor progression in primary nonsmall cell lung carcinoma. Cancer 2005; 104:1825-1833.
    • (2005) Cancer , vol.104 , pp. 1825-1833
    • Kim, J.S.1    Han, J.2    Shim, Y.M.3    Park, J.4    Kim, D.H.5
  • 8
    • 0029900157 scopus 로고    scopus 로고
    • H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer
    • Lee SW, H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nat Med 1996; 2:776-782.
    • (1996) Nat Med , vol.2 , pp. 776-782
    • Lee, S.W.1
  • 9
    • 16844370333 scopus 로고    scopus 로고
    • T-cadherin negatively regulates the proliferation of cutaneous squamous carcinoma cells
    • Mukoyama Y, Zhou S, Miyachi Y, Matsuyoshi N. T-cadherin negatively regulates the proliferation of cutaneous squamous carcinoma cells. J Invest Dermatol 2005; 124:833-838.
    • (2005) J Invest Dermatol , vol.124 , pp. 833-838
    • Mukoyama, Y.1    Zhou, S.2    Miyachi, Y.3    Matsuyoshi, N.4
  • 10
    • 4143090637 scopus 로고    scopus 로고
    • Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancer
    • Sakai M, Hibi K, Koshikawa K, et al. Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancer. Cancer Sci 2004; 95:588-591.
    • (2004) Cancer Sci , vol.95 , pp. 588-591
    • Sakai, M.1    Hibi, K.2    Koshikawa, K.3
  • 11
    • 0031683862 scopus 로고    scopus 로고
    • The H-cadherin (CDH13) gene is inactivated in human lung cancer
    • Sato M, Mori Y, Sakurada A, Fujimura S, Horii A. The H-cadherin (CDH13) gene is inactivated in human lung cancer. Hum Genet 1998; 103:96-101.
    • (1998) Hum Genet , vol.103 , pp. 96-101
    • Sato, M.1    Mori, Y.2    Sakurada, A.3    Fujimura, S.4    Horii, A.5
  • 13
    • 53149102075 scopus 로고    scopus 로고
    • Insights into the low adhesive capacity of human T-cadherin from the NMR structure of Its N-terminal extracellular domain
    • Dames SA, Bang E, Haussinger D, Ahrens T, Engel J, Grzesiek S. Insights into the low adhesive capacity of human T-cadherin from the NMR structure of Its N-terminal extracellular domain. J Biol Chem 2008; 283:23485-23495.
    • (2008) J Biol Chem , vol.283 , pp. 23485-23495
    • Dames, S.A.1    Bang, E.2    Haussinger, D.3    Ahrens, T.4    Engel, J.5    Grzesiek, S.6
  • 14
    • 77949261544 scopus 로고    scopus 로고
    • T-cadherin structures reveal a novel adhesive binding mechanism
    • Ciatto C, Bahna F, Zampieri N, et al. T-cadherin structures reveal a novel adhesive binding mechanism. Nat Struct Mol Biol 2010; 17:339-347.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 339-347
    • Ciatto, C.1    Bahna, F.2    Zampieri, N.3
  • 17
    • 34347215518 scopus 로고    scopus 로고
    • Analysis of apoptosis by propidium iodide staining and flow cytometry
    • Riccardi C, Nicoletti I. Analysis of apoptosis by propidium iodide staining and flow cytometry. Nat Protoc 2006; 1:1458-1461.
    • (2006) Nat Protoc , vol.1 , pp. 1458-1461
    • Riccardi, C.1    Nicoletti, I.2
  • 18
    • 78549258808 scopus 로고    scopus 로고
    • Sensitization of melanoma cells for death ligand-induced apoptosis by an indirubin derivative-Enhancement of both extrinsic and intrinsic apoptosis pathways
    • Berger A, Quast SA, Plotz M, et al. Sensitization of melanoma cells for death ligand-induced apoptosis by an indirubin derivative-Enhancement of both extrinsic and intrinsic apoptosis pathways. Biochem Pharmacol 2011; 81:71-81.
    • (2011) Biochem Pharmacol , vol.81 , pp. 71-81
    • Berger, A.1    Quast, S.A.2    Plotz, M.3
  • 19
    • 84855696067 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma
    • Biechele TL, Kulikauskas RM, Toroni RA, et al. Wnt/beta-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma. Sci Signal 2012; 5:ra3.
    • (2012) Sci Signal , vol.5
    • Biechele, T.L.1    Kulikauskas, R.M.2    Toroni, R.A.3
  • 21
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME. Cellular survival: A play in three Akts. Genes Dev 1999; 13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 22
    • 35248896777 scopus 로고    scopus 로고
    • Integrin-linked kinase is an essential mediator for T-cadherin-dependent signaling via Akt and GSK3beta in endothelial cells
    • Joshi MB, Ivanov D, Philippova M, Erne P, Resink TJ. Integrin-linked kinase is an essential mediator for T-cadherin-dependent signaling via Akt and GSK3beta in endothelial cells. FASEB J 2007; 21:3083-3095.
    • (2007) FASEB J , vol.21 , pp. 3083-3095
    • Joshi, M.B.1    Ivanov, D.2    Philippova, M.3    Erne, P.4    Resink, T.J.5
  • 23
    • 4944249733 scopus 로고    scopus 로고
    • Deregulated Akt3 activity promotes development of malignant melanoma
    • Stahl JM, Sharma A, Cheung M, et al. Deregulated Akt3 activity promotes development of malignant melanoma. Cancer Res 2004; 64:7002-7010.
    • (2004) Cancer Res , vol.64 , pp. 7002-7010
    • Stahl, J.M.1    Sharma, A.2    Cheung, M.3
  • 24
    • 40449133794 scopus 로고    scopus 로고
    • T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model
    • Hebbard LW, Garlatti M, Young LJ, Cardiff RD, Oshima RG, Ranscht B. T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model. Cancer Res 2008; 68:1407-1416.
    • (2008) Cancer Res , vol.68 , pp. 1407-1416
    • Hebbard, L.W.1    Garlatti, M.2    Young, L.J.3    Cardiff, R.D.4    Oshima, R.G.5    Ranscht, B.6
  • 25
    • 0034282710 scopus 로고    scopus 로고
    • Increased expression of H/T-cadherin in tumor-penetrating blood vessels
    • Wyder L, Vitaliti A, Schneider H, et al. Increased expression of H/T-cadherin in tumor-penetrating blood vessels. Cancer Res 2000; 60:4682-4688.
    • (2000) Cancer Res , vol.60 , pp. 4682-4688
    • Wyder, L.1    Vitaliti, A.2    Schneider, H.3
  • 27
    • 34548188716 scopus 로고    scopus 로고
    • T-cadherin suppresses angiogenesis in vivo by inhibiting migration of endothelial cells
    • Rubina K, Kalinina N, Potekhina A, et al. T-cadherin suppresses angiogenesis in vivo by inhibiting migration of endothelial cells. Angiogenesis 2007; 10:183-195.
    • (2007) Angiogenesis , vol.10 , pp. 183-195
    • Rubina, K.1    Kalinina, N.2    Potekhina, A.3
  • 28
    • 34548410347 scopus 로고    scopus 로고
    • Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: A role for T-cadherin in tumor angiogenesis
    • Ghosh S, Joshi MB, Ivanov D, et al. Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: A role for T-cadherin in tumor angiogenesis. FEBS Lett 2007; 581:4523-4528.
    • (2007) FEBS Lett , vol.581 , pp. 4523-4528
    • Ghosh, S.1    Joshi, M.B.2    Ivanov, D.3
  • 29
    • 70350532679 scopus 로고    scopus 로고
    • Extracellular cadherin repeat domains EC1 and EC5 of T-cadherin are essential for its ability to stimulate angiogenic behavior of endothelial cells
    • Joshi MB, Kyriakakis E, Pfaff D, et al. Extracellular cadherin repeat domains EC1 and EC5 of T-cadherin are essential for its ability to stimulate angiogenic behavior of endothelial cells. FASEB J 2009; 23:4011-4021.
    • (2009) FASEB J , vol.23 , pp. 4011-4021
    • Joshi, M.B.1    Kyriakakis, E.2    Pfaff, D.3
  • 30
    • 58149315994 scopus 로고    scopus 로고
    • A requirement for thioredoxin in redox-sensitive modulation of T-cadherin expression in endothelial cells
    • Joshi MB, Ivanov D, Philippova M, Kyriakakis E, Erne P, Resink TJ. A requirement for thioredoxin in redox-sensitive modulation of T-cadherin expression in endothelial cells. Biochem J 2008; 416:271-280.
    • (2008) Biochem J , vol.416 , pp. 271-280
    • Joshi, M.B.1    Ivanov, D.2    Philippova, M.3    Kyriakakis, E.4    Erne, P.5    Resink, T.J.6
  • 31
    • 47249149299 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells
    • Chan DW, Lee JM, Chan PC. Ng IO. Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells. Int J Cancer 2008; 123:1043-1052.
    • (2008) Int J Cancer , vol.123 , pp. 1043-1052
    • Chan, D.W.1    Lee, J.M.2    Chan, P.C.3    Ng, I.O.4
  • 32
    • 33846973344 scopus 로고    scopus 로고
    • The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by phenoxodiol is associated with carboplatin sensitization
    • Kluger HM, McCarthy MM, Alvero AB, et al. The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by phenoxodiol is associated with carboplatin sensitization. J Transl Med 2007; 5:6.
    • (2007) J Transl Med , vol.5 , pp. 6
    • Kluger, H.M.1    McCarthy, M.M.2    Alvero, A.B.3
  • 34
    • 77955757007 scopus 로고    scopus 로고
    • Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells
    • Shao Y, Aplin AE. Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells. Cancer Res 2010; 70:6670-6681.
    • (2010) Cancer Res , vol.70 , pp. 6670-6681
    • Shao, Y.1    Aplin, A.E.2
  • 35
    • 0033618371 scopus 로고    scopus 로고
    • Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
    • Nakatani K, Thompson DA, Barthel A, et al. Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J Biol Chem 1999; 274:21528-21532.
    • (1999) J Biol Chem , vol.274 , pp. 21528-21532
    • Nakatani, K.1    Thompson, D.A.2    Barthel, A.3
  • 36
    • 33846252336 scopus 로고    scopus 로고
    • A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition
    • Cristiano BE, Chan JC, Hannan KM, et al. A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition. Cancer Res 2006; 66:11718-11725.
    • (2006) Cancer Res , vol.66 , pp. 11718-11725
    • Cristiano, B.E.1    Chan, J.C.2    Hannan, K.M.3
  • 37
    • 77149150596 scopus 로고    scopus 로고
    • T-cadherin modulates tumor-associated molecules in gallbladder cancer cells
    • Adachi Y, Takeuchi T, Nagayama T, Furihata M. T-cadherin modulates tumor-associated molecules in gallbladder cancer cells. Cancer Invest 28:120-126.
    • Cancer Invest , vol.28 , pp. 120-126
    • Adachi, Y.1    Takeuchi, T.2    Nagayama, T.3    Furihata, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.