Standardized deceased donor kidney donation rates in the UK reveal marked regional variation and highlight the potential for increasing kidney donation: A prospective cohort study

British Journal of Anaesthesia

Volumn 113, Issue 1, 2014, Pages 83-90

  Summers, D M ^a,b,c   Johnson, R J ^c   Hudson, A J ^c   Collett, D ^c   Murphy, P ^c   Watson, C J E ^a,b   Neuberger, J M ^c   Bradley, J A ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b and University of Bristol   (United Kingdom)

^c NHS BLOOD AND TRANSPLANT   (United Kingdom)

Author keywords

donors, organ transplantation; kidney, transplantation; model, statistical; surgery, transplantation; transplantation, kidney

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CAUSE OF DEATH; COHORT ANALYSIS; COMMERCIAL PHENOMENA; DEATH; DYING; EMERGENCY WARD; ETHNICITY; HUMAN; INFORMATION RETRIEVAL; INTENSIVE CARE; KIDNEY DONOR; KIDNEY TRANSPLANTATION; MEDICAL AUDIT; PRIORITY JOURNAL; PROSPECTIVE STUDY; REGIONAL VARIATION; UNITED KINGDOM;

DONORS, ORGAN TRANSPLANTATION; KIDNEY, TRANSPLANTATION; MODEL, STATISTICAL; SURGERY, TRANSPLANTATION; TRANSPLANTATION, KIDNEY;

ADOLESCENT; ADULT; AGE FACTORS; AGED; CAUSE OF DEATH; COHORT STUDIES; CRITICAL CARE NURSING; ETHNIC GROUPS; GREAT BRITAIN; HUMANS; INTENSIVE CARE UNITS; KIDNEY TRANSPLANTATION; MIDDLE AGED; PROSPECTIVE STUDIES; TISSUE AND ORGAN HARVESTING; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS; YOUNG ADULT;

EID: 84904017062     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aet473     Document Type: Article

References (30)

1. Tonelli M, Wiebe N, Knoll G, et al. Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant 2011; 11: 2093-109
2. Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999; 341: 1725-30
3. Garcia GG, Harden P, Chapman J, World Kidney Day Steering Committee 2012. The global role of kidney transplantation. Lancet 2012; 379: e36-8
4. Council of Europe. International figures on donation and transplantation 2011. Newsl Transplant [Internet] 17: 34-40. Available from http://www.ont.es/ publicaciones/Paginas/Publicaciones.aspx (accessed 26 November 2013)
5. Locke J, Segev D, Warren D, Dominici F, Simpkins C, Montgomery R. Outcomes of kidneys from donors after cardiac death: implications for allocation and preservation.AmJ Transplant 2007; 7: 1797-807
6. Summers DM, Johnson RJ, Allen J, et al. Analysis of factors that affect outcome after transplantation of kidneys donated after cardiac death in the UK: a cohort study. Lancet 2010; 376: 1303-11
7. Summers DM, Johnson RJ, Hudson A, Collett D, Watson CJ, Bradley JA. Effect of donor age and cold storage time on outcome in recipients of kidneys donated after circulatory death in the UK: a cohort study. Lancet 2013; 381: 727-34
8. OrganDonation Taskforce. Organs for transplants:a report fromthe Organ Donation Taskforce [Internet]. Department of Health. 2008. [cited 2012 25/03/2012]. Available from http://www.nhsbt.nhs.uk/ to2020/resources/ OrgansfortransplantsTheOrganDonorTaskForce 1streport.pdf (accessed 26 November 2013)
9. UK Donation Ethics Committee. AnEthical Framework for Controlled Donation after Circulatory Death [Internet]. AcademyofRoyalMedical Colleges. 2011. [cited 2012 Jun 25]. Available from http://www. aomrc.org.uk/publications/ reports-a-guidance.html (accessed 26 November 2013)
10. British Transplantation Society and The Intensive Care Society. Donation after circulatory death: report of a consensus meeting [Internet]. bts.org.uk. 2010. [cited 2012 Jun 25]. Available from http://www.bts.org.uk/Documents/ Guidelines/Active/DCD for BTS and ICS FINAL.pdf (accessed 26 November 2013)
11. Council of Europe. International figures on donation and transplantation- 2007. Newsl Transplant [Internet] 13: 23-9. Available from http://www.ont.es/ publicaciones/Documents/Newsletter2008. pdf (accessed 26 November 2013)
12. Reid AWN, Harper S, Jackson CH, et al. Expansion of the kidney donorpoolbyusingcardiacdeathdonorswithprolongedtimetocardiorespiratory arrest.AmJ Transplant [Internet] 2011; 11: 995-1005
13. Johnson R, Fuggle S, Mumford L, Bradley J, Forsythe J, Rudge C. A New UK 2006 National Kidney Allocation Scheme for deceased heart-beating donor kidneys. Transplantation 2010; 89: 387-94
14. Barber K, Falvey S, Hamilton C, Collett D, Rudge C. Potential fororgan donation in the United Kingdom: audit of intensive care records. Br Med J 2006; 332: 1124-7
15. Spiegelhalter DJ. Funnel plots for comparing institutional performance. Stat Med 2005; 24: 1185-202
16. Barber KM, Hussey JC, Bond ZC, Falvey SJ, Collett D, Rudge CJ. TheUK National Potential Donor Audit. Transplant Proc 2005; 37: 568-70
17. Simpkin AL, Robertson LC, Barber VS, Young JD. Modifiable factors influencing relatives' decision to offer organ donation: systematic review. Br Med J 2009; 338: b991
18. Davis C, Randhawa G. The influence of religion on organ donation and transplantation among the Black Caribbean and Black African population-a pilot study in the United Kingdom. Ethn Dis 2006; 16: 281-5
19. Randhawa G. Death and organ donation: meeting the needs of multiethnic and multifaith populations. Br J Anaesth 2012; 108 Suppl 1: i88-91
20. NHSBT. Black and Asian Organ Donation Campaign [Internet]. organdonation.nhs.uk. [cited 2013 Feb 4]. Available from http://www. organdonation.nhs.uk/campaigns/other-campaigns/black- and-asian/index.asp (accessed 26 November 2013)
21. Rhodes A, Ferdinande P, Flaatten H, Guidet B, Metnitz PG, Moreno RP. The variability of critical care bed numbers in Europe. Intensive Care Med 2012; 38: 1647-53
22. Crimmins DW, Palmer JD. Snapshot viewof emergency neurosurgical head injury care in Great Britain and Ireland. J Neurol Neurosurg Psychiatr 2000; 68: 8-13
23. Rao P, Schaubel D, Guidinger M, et al. A comprehensive risk quantification score for deceased donor kidneys: the kidney donor risk index. Transplantation 2009; 88: 231-6
24. NHSBT. Transplant activity in the UK-activity report 2010-11 [Internet]. 2011. [cited 2012 Jun 18]. Available from http://www. organdonation.nhs.uk/ statistics/transplant-activity-report/archive- activity-reports/ (accessed 26 November 2013)
25. NHSBT. Median Waiting Time to Kidney Transplant [Internet]. organdonation.nhs.uk. [cited 2012 Jun 18]. Available from http://www. organdonation.nhs.uk/ukt/statistics/centre-specific-reports/ pdf/waiting-time-to-transplant.pdf (accessed26November2013)
26. Mallik M, Callaghan CJ, Hope M, et al. Comparison of liver transplantation outcomes from adult split liver and circulatory death donors. Br J Surg 2012; 99: 839-47
27. Qureshi MS, Callaghan CJ, Bradley JA, Watson CJ, Pettigrew GJ. Outcomes of simultaneous pancreas-kidney transplantation from brain-dead and controlled circulatory death donors. Br J Surg 2012; 99: 831-8
28. Summers DM, Counter C, Johnson RJ, Murphy PG, Neuberger JM, Bradley JA. Is the increase in DCD organ donors in the United Kingdom contributing to a decline in DBD donors? Transplantation 2010; 90: 1506-10
29. Saidi RF, Bradley J, Greer D, et al. Changing pattern of organ donation atasinglecenter: arepotential braindeaddonorsbeinglost todonation after cardiac death? Am J Transplant 2010; 10: 2536-40
30. Bion JF, Nightingale P, Taylor BL. Will the UK ever reach international levels of organ donation? Br J Anaesth 2012; 108 (Suppl. 1): i10-3