γδ T cells and CD14+ monocytes are predominant cellular sources of cytokines and chemokines associated with severe malaria

Journal of Infectious Diseases

Volumn 210, Issue 2, 2014, Pages 295-305

  Stanisic, Danielle I ^a,b,h   Cutts, Julia ^a   Eriksson, Emily ^a,c   Fowkes, Freya J I ^d   Rosanas Urgell, Anna ^b,i   Siba, Peter ^b   Laman, Moses ^b,e   Davis, Timothy M E ^e   Manning, Laurens ^e   Mueller, Ivo ^a,b,f   Schofield, Louis ^a,g  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d BURNET INSTITUTE   (Australia)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^f CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^g JAMES COOK UNIVERSITY   (Australia)

^h GRIFFITH UNIVERSITY   (Australia)

ⁱ INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

monocyte macrophages

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 2; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CASE CONTROL STUDY; CD4+ T LYMPHOCYTE; CELL VIABILITY; CLINICAL FEATURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DISEASE SEVERITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INCIDENCE; INNATE IMMUNITY; MALARIA; MONOCYTE; PAPUA NEW GUINEA; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM VIVAX MALARIA; PRIORITY JOURNAL;

CHEMOKINES; CYTOKINES; MONOCYTE/MACROPHAGES; SEVERE MALARIA; ΓΔ T CELLS;

ANTIGENS, CD14; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CYTOKINES; FEMALE; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; MONOCYTES; PAPUA NEW GUINEA; PLASMODIUM FALCIPARUM; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES;

EID: 84903978177     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu083     Document Type: Article

References (40)

1. Clark IA. Cell-mediated immunity in protection and pathology of malaria. Parasitol Today 1987; 3:300-5. (Pubitemid 17147470)
2. Clark IA, Budd AC, Alleva LM, Cowden WB. Human malarial disease: a consequence of inflammatory cytokine release. Malar J 2006; 5:85.
3. Schofield L, Grau GE. Immunological processes in malaria pathogenesis. Nat Rev Immunol 2005; 5:722-35. (Pubitemid 43086173)
4. Currier J, Beck HP, Currie B, Good MF. Antigens released at schizont burst stimulate Plasmodium falciparum-specific CD4+ T cells from non-exposed donors: potential for cross-reactive memory T cells to cause disease. Int Immunol 1995; 7:821-33.
5. Artavanis-Tsakonas K, Riley E. Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes. J Immunol 2002; 169: 2956-63. (Pubitemid 35013137)
6. D'Ombrain M, Hansen D, Simpson K, Schofield L. Gamma delta T cells expressing NK receptors predominate over NK cells and conventional T cells in the innate IFN-G responses to Plasmodium falciparum malaria. Eur J Immunol 2007; 37:1864-73. (Pubitemid 47065125)
7. Agudelo O, Bueno J, Villa A, Maestre A. High IFN-gamma and TNF production by peripheral NK cells of Colombian patients with different clinical presentation of Plasmodium falciparum. Malar J 2012; 11:38.
8. Luty AJ, Lell B, Schmidt-Ott R, et al. Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children. J Infect Dis 1999; 179:980-8. (Pubitemid 29159345)
9. Dodoo D, Omer FM, Todd J, Akanmori BD, Koram KA, Riley EM. Absolute levels and ratios of proinflammatory and anti-inflammatory cytokine production in vitro predict clinical immunity to Plasmodium falciparum malaria. J Infect Dis 2002; 185:971-9. (Pubitemid 34274441)
10. D'Ombrain M, Robinson L, Stanisic D, et al. Association of early interferon-gamma production with immunity to clinical malaria: a longitudinal study among Papua New Guinean children. Clin Infect Dis 2008; 47:1380-7.
11. Robinson L, D'Ombrain M, Stanisic D, et al. Cellular tumour necrosis factor, gamma interferon, and interleukin-6 responses as correlates of immunity and risk of clinical Plasmodium falciparum malaria in children from Papua New Guinea. Infect Immun 2009; 77: 3033-43.
12. Grau GE, Taylor TE, Molyneux ME, et al. Tumor necrosis factor and disease severity in children with falciparum malaria. N Engl J Med 1989; 320:1586-91. (Pubitemid 19154572)
13. Kern P, Hemmer CJ, Van Damme J, Gruss HJ, Dietrich M. Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria. Am J Med 1989; 87:139-43. (Pubitemid 19201633)
14. Burgmann H, Hollenstein U,Wenisch C, Thalhammer F, Looareesuwan S, Graninger W. Serum concentrations of MIP-1 alpha and interleukin-8 in patients suffering from acute Plasmodium falciparum malaria. Clin Immunol Immunopathol 1995; 76:32-6.
15. Awandare G, Goka B, Boeuf P, et al. Increased levels of inflammatory mediators in children with severe Plasmodium falciparum malaria with respiratory distress. J Infect Dis 2006; 194:1438-46. (Pubitemid 44706513)
16. Ochiel DO, Awandare GA, Keller CC, et al. Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria. Infect Immun 2005; 73:4190-7. (Pubitemid 40923161)
17. Ayimba E, Hegewald J, Segbena AY, et al. Proinflammatory and regulatory cytokines and chemokines in infants with uncomplicated and severe Plasmodium falciparum malaria. Clin Exp Immunol 2011; 166:218-26.
18. Bostrom S, Giusti P, Arama C, et al. Changes in the levels of cytokines, chemokines and malaria-specific antibodies in response to Plasmodium falciparum infection in children living in sympatry in Mali. Malar J 2012; 11:109.
19. Erdman LK, Dhabangi A, Musoke C, et al. Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study. Plos One 2011; 6:e17440.
20. Sinha S, Qidwai T, Kanchan K, et al. Distinct cytokine profiles define clinical immune response to falciparum malaria in regions of high or low disease transmission. Eur Cytokine Netw 2010; 21:232-40.
21. Engelberts I, Stephens S, Francot GJ, van der Linden CJ, Buurman WA. Evidence for different effects of soluble TNF-receptors on various TNF measurements in human biological fluids. Lancet 1991; 338:515-6.
22. Ho M, Webster HK, Green B, Looareesuwan S, Kongchareon S, White NJ. Defective production of and response to IL-2 in acute human falciparum malaria. J Immunol 1988; 141:2755-9. (Pubitemid 18263064)
23. Kremsner PG, Zotter GM, Feldmeier H, et al. Immune response in patients during and after Plasmodium falciparum infection. J Infect Dis 1990; 161:1025-8. (Pubitemid 20148347)
24. Hviid L, Kurtzhals J, Goka B, Oliver-Commey J, Nkrumah F, Theander T. Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria. Infect Immun 1997; 65:4090-3. (Pubitemid 27422063)
25. Troye-Blomberg M, Perlmann H, Patattoyo M, Perlmann P. Regulation of the immune response in Plasmodium falciparum malaria II. Antigen specific proliferative responses in vitro. Clin Exp Immunol 1983; 53:345-53. (Pubitemid 13076716)
26. Elhassan I, Hviid L, Satti G, et al. Evidence of endothelial inflammation, T cell activation, and T cell reallocation in uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg 1994; 51:372-9. (Pubitemid 24300832)
27. Manning L, Laman M, Law I, et al. Features and prognosis of severe malaria caused by Plasmodium falciparum, Plasmodium vivax and mixed Plasmodium species in Papua New Guinean children. Plos One 2011; 6: e29203.
28. Muller I, Bockarie M, Alpers M, Smith T. The epidemiology of malaria in Papua New Guinea. Trends Parasitol 2003; 19:253-9. (Pubitemid 36638726)
29. Severe falciparum malaria.World Health Organization, Communicable Diseases Cluster. Trans R Soc Trop Med Hyg 2000; 94(Suppl 1):S1-90.
30. Molyneux ME, Taylor TE,Wirima JJ, Borgstein A. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. Q J Med 1989; 71:441-59. (Pubitemid 19161768)
31. Snounou G, Viriyakosol S, Zhu XP, et al. High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol 1993; 61:315-20.
32. Rosanas-Urgell A, Mueller D, Betuela I, et al. Comparison of diagnostic methods for the detection and quantification of the four sympatric Plasmodium species in field samples from Papua New Guinea. Malar J 2010; 9:361.
33. Armah HB, Wilson NO, Sarfo BY, et al. Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J 2007; 6:147.
34. Jain V, Armah HB, Tongren JE, et al. Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. Malar J 2008; 7:83.
35. Abrams ET, Brown H, Chensue SW, et al. Host response to malaria during pregnancy: placental monocyte recruitment is associated with elevated beta chemokine expression. J Immunol 2003; 170:2759-64. (Pubitemid 36245671)
36. Shen Y, Zhou D, Qiu L, et al. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science 2002; 295:2255-8. (Pubitemid 34258837)
37. Dieli F, Poccia F, Lipp M, et al. Differentiation of effector/memory Vdelta2 T cells and migratory routes in lymph nodes or inflammatory sites. J Exp Med 2003; 198:391-7. (Pubitemid 36980610)
38. Eberl M, Engel R, Beck E, Jomaa H. Differentiation of human gammadelta T cells towards distinct memory phenotypes. Cell Immunol 2002; 218:1-6. (Pubitemid 36027085)
39. Hoft DF, Brown RM, Roodman ST. Bacille Calmette-Guerin vaccination enhances human gamma delta T cell responsiveness to mycobacteria suggestive of a memory-like phenotype. J Immunol 1998; 161: 1045-54. (Pubitemid 28323573)
40. Fournie JJ, Sicard H, Poupot M, et al. What lessons can be learned from: T cell-based cancer immunotherapy trials? Cell Mol Immunol 2013; 10:35-41.