Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1Β

Molecular Pharmaceutics

Volumn 11, Issue 7, 2014, Pages 2203-2212

  Lin, Hang ^a   Lozito, Thomas P ^a   Alexander, Peter G ^a   Gottardi, Riccardo ^a,b   Tuan, Rocky S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b RiMED Foundation   (Italy)

Author keywords

interleukin 1 ; matrix metalloproteinase; mesenchymal stem cells; osteoarthritis; osteochondral tissue engineering

Indexed keywords

ACN PROTEIN; AGGRECAN; BONE SIALOPROTEIN; COL2 PROTEIN; COLLAGEN TYPE 2; COLLAGENASE 3; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; OCN PROTEIN; OSTEOCALCIN; PROTEIN; RNA 18S; STROMELYSIN; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BONE TISSUE; CASE REPORT; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MESENCHYMAL STEM CELL; MICROFLUIDICS; OSTEOARTHRITIS; OSTEOBLAST; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; TISSUE REACTION; ULTRAVIOLET RADIATION; ARTICULAR CARTILAGE; BASOPHIL; BIOREACTOR; BONE DEVELOPMENT; CELL CULTURE; CELL DIFFERENTIATION; CHONDROGENESIS; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PROCEDURES; STEM CELL;

ADULT; AGED; BASOPHILS; BIOREACTORS; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROGENESIS; FEMALE; GENE EXPRESSION; HUMANS; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASES; MIDDLE AGED; OSTEOGENESIS; STEM CELLS; TISSUE ENGINEERING;

EID: 84903976058     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500136b     Document Type: Article

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