In situ measurement of transport between subchondral bone and articular cartilage

Journal of Orthopaedic Research

Volumn 27, Issue 10, 2009, Pages 1347-1352

  Pan, Jun ^a,b   Zhou, Xiaozhou ^a   Li, Wen ^a   Novotny, John E ^a   Doty, Stephen B ^c   Wang, Liyun ^a  

^a UNIVERSITY OF DELAWARE   (United States)

^b CHONGQING UNIVERSITY   (China)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Calcified cartilage; Diffusion; Mineralization; Osteoarthritis; Photobleaching

Indexed keywords

FLUORESCEIN SODIUM; TRACER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BLEACHING; BONE; CALCIFICATION; CARTILAGE MATRIX; CONFOCAL LASER MICROSCOPY; DIFFUSION COEFFICIENT; ELECTRON MICROSCOPE; ELECTRON MICROSCOPY; FEMUR CONDYLE; FLUORESCENCE; FLUORESCENCE LOSS INDUCED BY PHOTOBLEACHING; MEASUREMENT; MINERALIZATION; MOUSE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; BIOLOGICAL TRANSPORT; BIOMECHANICS; CARTILAGE, ARTICULAR; CELL COMMUNICATION; CHONDROCYTES; FEMUR; FLUORESCEIN; JOINTS; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; MODELS, THEORETICAL; OSTEOCYTES;

EID: 70349213369     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20883     Document Type: Article

References (30)

1. Mente PL, Lewis JL. 1994. Elastic-Modulus of calcified cartilage is an order of magnitude less than that of subchondral bone. J Orthop Res 12:637-647.
2. Radin EL, Martin RB, Burr DB, et al. 1984. Effects of mechanical loading on the tissues of the rabbit knee. J Orthop Res 2:221-234. (Pubitemid 15220006)
3. Dequeker J, Mokassa L, Aerssens J, et al. 1997. Bone density and local growth factors in generalized osteoarthritis. Microsc Res Tech 37:358-371. (Pubitemid 27247063)
4. Burr DB. 2004. Anatomy and physiology of the mineralized tissues: role in the pathogenesis of osteoarthrosis. Osteoarth Cart 12(Suppl A):S20-30.
5. Aspden RM. 2008. Osteoarthritis: a problem of growth not decay? Rheumatology (Oxford) 47:1452-1460.
6. Li B, Aspden RM. 1997. Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis. Ann Rheum Dis 56:247-254. (Pubitemid 27239581)
7. Westacott CI, Webb GR, Warnock MG, et al. 1997. Alteration of cartilage metabolism by cells from osteoarthritic bone. Arthritis Rheum 40:1282-1291. (Pubitemid 27430140)
8. Lajeunesse D, Reboul P. 2003. Subchondral bone in osteoarthritis: a biologic link with articular cartilage leading to abnormal remodeling. Curr Opin Rheumatol 15:628-633. (Pubitemid 37041404)
9. Brower TD, Akahoshi Y, Orlic P. 1962. The Diffusion of Dyes Through Articular Cartilage in Vivo. J Bone Joint Surg Am 44:456-463.
10. Maroudas A, Bullough P, Swanson SA, et al. 1968. The permeability of articular cartilage. J Bone Joint Surg Br 50:166-177.
11. Honner R, Thompson RC. 1971. The nutritional pathways of articular cartilage. An autoradiographic study in rabbits using 35S injected intravenously. J Bone Joint Surg Am 53:742-748.
12. Ogata K, Whiteside LA. 1979. Barrier to material transfer at the bone-cartilage interface: measurement with hydrogen gas in vivo. Clin Orthop Relat Res 273-276. (Pubitemid 10152337)
13. Lane LB, Villacin A, Bullough PG. 1977. The vascularity and remodelling of subchondrial bone and calcified cartilage in adult human femoral and humeral heads. An age- and stress-related phenomenon. J Bone Joint Surg Br 59:272-278. (Pubitemid 8168937)
14. Clark JM. 1990. The structure of vascular channels in the subchondral plate. J Anat 171:105-115.
15. Imhof H, Sulzbacher I, Grampp S, et al. 2000. Subchondral bone and cartilage disease: a rediscovered functional unit. Invest Radiol 35:581-588. (Pubitemid 30758075)
16. Mori S, Harruff R, Burr DB. 1993. Microcracks in articular calcified cartilage of human femoral heads. Arch Pathol Lab Med 117:196-198. (Pubitemid 23057628)
17. Oegema TR Jr, Carpenter RJ, Hofmeister F, et al. 1997. The interaction of the zone of calcified cartilage and subchondral bone in osteoarthritis. Microsc Res Tech 37:324-332. (Pubitemid 27247060)
18. Burr DB, Radin EL. 2003. Microfractures and microcracks in subchondral bone: are they relevant to osteoarthrosis? Rheum Dis Clin North Am 29:675-685.
19. Arkill KP, Winlove CP. 2008. Solute transport in the deep and calcified zones of articular cartilage. Osteoarth Cart 16:708-714.
20. Jiang J, Nicoll SB, Lu HH. 2005. Co-culture of osteoblasts and chondrocytes modulates cellular differentiation in vitro. Biochem Biophys Res Commun 338:762-770. (Pubitemid 41597709)
21. Westacott C. 2002. Interactions between subchondral bone and cartilage in OA. Cells from osteoarthritic bone can alter cartilage metabolism. J Musculoskelet Neuronal Interact 2:507-509. (Pubitemid 36157586)
22. Massicotte F, Lajeunesse D, Benderdour M, et al. 2002. Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients. Osteoarth Cart 10:491-500. (Pubitemid 34679302)
23. Martel-Pelletier J, Lajeunesse D, Fahmi H, et al. 2006. New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets. Curr Rheumatol Rep 8:30-36. (Pubitemid 44659357)
24. Leddy HA, Guilak F. 2008. Site-specific effects of compression on macromolecular diffusion in articular cartilage. Biophys J 95:4890-4895.
25. Wang L, Wang Y, Han Y, et al. 2005. In situ measurement of solute transport in the bone lacunar-canalicular system. Proc Natl Acad Sci USA 102:11911-11916.
26. Leddy HA, Guilak F. 2003. Site-specific molecular diffusion in articular cartilage measured using fluorescence recovery after photobleaching. Ann Biomed Eng 31:753-760.
27. Nimer E, Schneiderman R, Maroudas A. 2003. Diffusion and partition of solutes in cartilage under static load. Biophys Chem 106:125-146. (Pubitemid 37222427)
28. Ferguson VL, Bushby AJ, Boyde A. 2003. Nanomechanical properties and mineral concentration in articular calcified cartilage and subchondral bone. J Anat 203:191-202. (Pubitemid 36974663)
29. Hwang J, Bae WC, Shieu W, Lewis CW, Bugbee WD, Sah RL. 2008. Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritis. Arthritis Rheum 58:3831-3842.
30. Hayami T, Pickarski M, Wesolowski GA, et al. 2004. The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum 50:1193-1206. (Pubitemid 38480830)