B4GALNT2 gene expression controls the biosynthesis of Sda and sialyl Lewis X antigens in healthy and cancer human gastrointestinal tract

International Journal of Biochemistry and Cell Biology

Volumn 53, Issue , 2014, Pages 442-449

  Groux Degroote, Sophie ^a   Wavelet, Cindy ^a   Krzewinski Recchi, Marie Ange ^a   Portier, Lucie ^a   Mortuaire, Marlène ^a   Mihalache, Adriana ^a   Trinchera, Marco ^b   Delannoy, Philippe ^a   Malagolini, Nadia ^c   Chiricolo, Mariella ^c   Dall'Olio, Fabio ^c   Harduin Lepers, Anne ^a  

^a UNIV LILLE   (France)

^b UNIVERSITY OF INSUBRIA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

B4GALNT2; Colon cancer; Glycosylation; Glycosyltransferases

Indexed keywords

B4GALNT2 PROTEIN; CARBOHYDRATE ANTIGEN; CARBOHYDRATE ANTIGEN SD A; FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE 6; PROTEIN; SIALYL LEWIS X ANTIGEN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BETA-1,4-N-ACETYL-GALACTOSAMINYL TRANSFERASE 2; CD15 ANTIGEN; CELL CYCLE PROTEIN; FUT6 PROTEIN, HUMAN; N ACETYLGALACTOSAMINYLTRANSFERASE; NUCLEAR PROTEIN; SDAD1 PROTEIN, HUMAN;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL LINE; CANCER TISSUE; CLINICAL ARTICLE; COLON CANCER; COLON MUCOSA; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; EXON; FEMALE; FETUS; FIBROBLAST CULTURE; GASTROINTESTINAL TRACT; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; BIOSYNTHESIS; COLON TUMOR; GENE EXPRESSION REGULATION; GENETICS; GLYCOSYLATION; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; TUMOR CELL LINE;

ADULT; AGED; ANTIGENS, CD15; CELL CYCLE PROTEINS; CELL LINE, TUMOR; COLONIC NEOPLASMS; FEMALE; FUCOSYLTRANSFERASES; GASTROINTESTINAL TRACT; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOSYLATION; HUMANS; MALE; MIDDLE AGED; N-ACETYLGALACTOSAMINYLTRANSFERASES; NUCLEAR PROTEINS;

EID: 84903949696     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.06.009     Document Type: Article

References (32)

1. D.A. Aas-Eng, H.C. Asheim, A. Deggerdal, E. Smeland, and S. Funderud Characterization of a promoter region supporting transcription of a novel human beta-galactoside alpha-2,6-sialyltransferase transcript in HepG2 cells Biochim. Biophys. Acta 1261 1995 166 169
2. C. Capon, E. Maes, J.C. Michalski, H. Leffler, and Y.S. Kim Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon Biochem. J. 358 2001 657 664 (Pubitemid 32896953)
3. F. Colomb, M.A. Krzewinski-Recchi, F. El Machhour, E. Mensier, S. Jaillard, and A. Steenackers et al. TNF regulates sialyl-Lewisx and 6-sulfo-sialyl-Lewisx expression in human lung through up-regulation of ST3GAL4 transcript isoform BX Biochimie 94 2012 2045 2053
4. F. Colomb, O. Vidal, M. Bobowski, M.A. Krzewinski-Recchi, A. Harduin-Lepers, and E. Mensier et al. TNF induces the expression of the sialyltransferase ST3 Gal IV in human bronchial mucosa via MSK1/2 protein kinases and increases FliD/sialyl-Lewisx-mediated adhesion of Pseudomonas aeruginosa Biochem. J. 457 2013 79 87
5. F. Dall'Olio, and M. Chiricolo Sialyltransferases in cancer Glycoconj. J. 18 2001 841 850 (Pubitemid 36315048)
6. F. Dall'Olio, N. Malagolini, M. Chiricolo, M. Trinchera, and A. Harduin-Lepers The expanding roles of the Sd(a)/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2 Biochim. Biophys. Acta 1840 2014 443 453
7. F. Dall'Olio, N. Malagolini, G. Di Stefano, M. Ciambella, and F. Serafini-Cessi Postnatal development of rat colon epithelial cells is associated with changes in the expression of the beta 1,4-N- acetylgalactosaminyltransferase involved in the synthesis of Sda antigen of alpha 2,6-sialyltransferase activity towards N-acetyl-lactosamine Biochem. J. 270 1990 519 524 (Pubitemid 20273498)
8. T. Dohi, N. Hanai, K. Yamaguchi, and M. Oshima Localization of UDP-GalNAc:NeuAc alpha 2,3Gal-R beta 1,4(GalNAc to Gal)N- acetylgalactosaminyltransferase in human stomach. Enzymatic synthesis of a fundic gland-specific ganglioside and GM2 J. Biol. Chem. 266 1991 24038 24043 (Pubitemid 21908901)
9. T. Dohi, and Y.I. Kawamura Incomplete synthesis of the Sda/Cad blood group carbohydrate in gastrointestinal cancer Biochim. Biophys. Acta 1780 2008 467 471 (Pubitemid 351381245)
10. T. Dohi, Y. Yuyama, Y. Natori, P.L. Smith, J.B. Lowe, and M. Oshima Detection of N-acetylgalactosaminyltransferase mRNA which determines expression of Sda blood group carbohydrate structure in human gastrointestinal mucosa and cancer Int. J. Cancer 67 1996 626 631 (Pubitemid 26300977)
11. J. Gomes, and C.A. Reis Immunodetection of glycosyltransferases in gastrointestinal tissues Methods Mol. Biol. 1022 2013 349 356
12. A. Harduin-Lepers, M.A. Krzewinski-Recchi, F. Colomb, F. Foulquier, S. Groux-Degroote, and P. Delannoy Sialyltransferases functions in cancers Front. Biosci. (Elite Ed). 4 2012 499 515
13. A. Harduin-Lepers, M.A. Krzewinski-Recchi, M. Hebbar, B. Samyn-Petit, V. Vallejo-Ruiz, and S. Julien et al. Sialyltransferases and breast cancer Recent Res. Dev. Cancer 3 2001 111 126
14. H. Ito, N. Hiraiwa, M. Sawada-Kasugai, S. Akamatsu, T. Tachikawa, and Y. Kasai et al. Altered mRNA expression of specific molecular species of fucosyl- and sialyl-transferases in human colorectal cancer tissues Int. J. Cancer 71 1997 556 564 (Pubitemid 27239364)
15. Y.I. Kawamura, R. Kawashima, R. Fukunaga, K. Hirai, N. Toyama-Sorimachi, and M. Tokuhara et al. Introduction of Sd(a) carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis Cancer Res. 65 2005 6220 6227 (Pubitemid 40994407)
16. Y.I. Kawamura, M. Toyota, R. Kawashima, T. Hagiwara, H. Suzuki, and K. Imai et al. DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer Gastroenterology 135 2008 142-51 e3
17. T. Kudo, Y. Ikehara, A. Togayachi, K. Morozumi, M. Watanabe, and M. Nakamura et al. Up-regulation of a set of glycosyltransferase genes in human colorectal cancer Lab. Invest. 78 1998 797 811 (Pubitemid 28347877)
18. L. Lo Presti, E. Cabuy, M. Chiricolo, and F. Dall'Olio Molecular cloning of the human beta1,4 N-acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain J. Biochem. 134 2003 675 682 (Pubitemid 38031267)
19. S.I. Macvie, J.A. Morton, and M.M. Pickles The reactions and inheritance of a new blood group antigen, Sda Vox sanguinis 13 1967 485 492
20. N. Malagolini, F. Dall'Olio, G. Di Stefano, F. Minni, D. Marrano, and F. Serafini-Cessi Expression of UDP-GalNAc:NeuAc alpha 2,3 Gal beta-R beta 1,4(GalNAc to Gal) N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen in human large intestine and colorectal carcinomas Cancer Res. 49 1989 6466 6470 (Pubitemid 20008771)
21. N. Malagolini, D. Santini, M. Chiricolo, and F. Dall'Olio Biosynthesis and expression of the Sda and sialyl Lewis x antigens in normal and cancer colon Glycobiology 17 2007 688 697 (Pubitemid 47050658)
22. Y. Misonou, K. Shida, H. Korekane, Y. Seki, S. Noura, and M. Ohue et al. Comprehensive clinico-glycomic study of 16 colorectal cancer specimens: elucidation of aberrant glycosylation and its mechanistic causes in colorectal cancer cells J. Proteome Res. 8 2009 2990 3005
23. M.D. Montiel, M.A. Krzewinski-Recchi, P. Delannoy, and A. Harduin-Lepers Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain Biochem. J. 373 2003 369 379 (Pubitemid 36897840)
24. J.A. Morton, M.M. Pickles, and A.M. Terry The Sda blood group antigen in tissues and body fluids Vox sanguinis 19 1970 472 482
25. M.W. Pfaffl A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res. 29 2001 e45
26. C. Robbe-Masselot, A. Herrmann, E. Maes, I. Carlstedt, J.C. Michalski, and C. Capon Expression of a core 3 disialyl-Le(x) hexasaccharide in human colorectal cancers: a potential marker of malignant transformation in colon J. Proteome Res. 8 2009 702 711
27. C. Robbe-Masselot, E. Maes, M. Rousset, J.C. Michalski, and C. Capon Glycosylation of human fetal mucins: a similar repertoire of O-glycans along the intestinal tract Glycoconj. J. 26 2009 397 413
28. C. Robbe, C. Capon, E. Maes, M. Rousset, A. Zweibaum, and J.P. Zanetta et al. Evidence of regio-specific glycosylation in human intestinal mucins: presence of an acidic gradient along the intestinal tract J. Biol. Chem. 278 2003 46337 46348 (Pubitemid 37452204)
29. F. Schwarz, and M. Aebi Mechanisms and principles of N-linked protein glycosylation Curr. Opin. Struct. Biol. 21 2011 576 582
30. F. Serafini-Cessi, N. Malagolini, S. Guerrini, and I. Turrini A soluble form of Sda-beta 1,4-N-acetylgalactosaminyltransferase is released by differentiated human colon carcinoma CaCo-2 cells Glycoconj. J. 12 1995 773 779 (Pubitemid 26018872)
31. M. Trinchera, N. Malagolini, M. Chiricolo, D. Santini, F. Minni, and A. Caretti et al. The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach Int. J. Biochem. Cell Biol. 43 2011 130 139
32. H.R. Wang, C.Y. Hsieh, Y.C. Twu, and L.C. Yu Expression of the human Sd(a) beta-1,4-N-acetylgalactosaminyltransferase II gene is dependent on the promoter methylation status Glycobiology 18 2008 104 113