Cideb facilitates the lipidation of chylomicrons in the small intestine

Journal of Lipid Research

Volumn 55, Issue 7, 2014, Pages 1279-1287

  Zhang, Li Jun ^a,b   Wang, Chao ^a,b   Yuan, Yuan ^a   Wang, Hui ^a   Wu, Jie ^a   Liu, Fang ^a   Li, Le ^a   Gao, Xing ^a   Zhao, Yuan Lin ^a   Hu, Pei Zhen ^a   Li, Peng ^c   Ye, Jing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c TSINGHUA UNIVERSITY   (China)

Author keywords

Cell deathinducing DNA fragmentation factor like effector b; Lipid absorption; Lipid droplet

Indexed keywords

APOLIPOPROTEIN B48; CELL DEATH INDUCING DFF45 LIKE EFFECTOR B; CHYLOMICRON; PERILIPIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; APOPTOSIS REGULATORY PROTEIN; CIDEB PROTEIN, HUMAN; CIDEB PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CACO 2 CELL LINE; CHEMICAL REACTION; CONTROLLED STUDY; ILEUM; INTESTINE CELL; JEJUNUM; LIPID DIET; LIPID STORAGE; LIPIDATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; UPREGULATION; ANIMAL; CACO-2 CELL LINE; GENETICS; HUMAN; LIPOYLATION; METABOLISM; MUTANT MOUSE STRAIN; PHYSIOLOGY; SMALL INTESTINE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CACO-2 CELLS; CHYLOMICRONS; HUMANS; INTESTINE, SMALL; LIPOYLATION; MICE; MICE, MUTANT STRAINS;

EID: 84903942459     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M046482     Document Type: Article

References (25)

1. Iqbal, J., and M. M. Hussain. 2009. Intestinal lipid absorption. Am. J. Physiol. Endocrinol. Metab. 296: E1183-E1194.
2. Gantz, D., S. Bennett Clark, A. Derksen, and D. M. Small. 1990. Size and shape determination of fi xed chylomicrons and emulsions with fl uid or solid surfaces by three-dimensional analysis of shadows. J. Lipid Res. 31: 163-171.
3. Hamilton, R. L., J. S. Wong, C. M. Cham, L. B. Nielsen, and S. G. Young. 1998. Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B defi ciency. J. Lipid Res. 39: 1543-1557.
4. Cartwright, I. J., and J. A. Higgins. 2001. Direct evidence for a twostep assembly of ApoB48-containing lipoproteins in the lumen of the smooth endoplasmic reticulum of rabbit enterocytes. J. Biol. Chem. 276: 48048-48057.
5. Fisher, E. A., and H. N. Ginsberg. 2002. Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins. J. Biol. Chem. 277: 17377-17380.
6. Rutledge, A. C., Q. Su, and K. Adeli. 2010. Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly. Biochem. Cell Biol. 88: 251-267.
7. White, D. A., A. J. Bennett, M. A. Billett, and A. M. Salter. 1998. The assembly of triacylglycerol-rich lipoproteins: an essential role for the microsomal triacylglycerol transfer protein. Br. J. Nutr. 80: 219-229.
8. Siddiqi, S. A., S. Siddiqi, J. Mahan, K. Peggs, F. S. Gorelick, and C. M. Mansbach 2nd. 2006. The identifi cation of a novel endoplasmic reticulum to Golgi SNARE complex used by the prechylomicron transport vesicle. J. Biol. Chem. 281: 20974-20982.
9. Siddiqi, S. A., J. Mahan, S. Siddiqi, F. S. Gorelick, and C. M. Mansbach 2nd. 2006. Vesicle-associated membrane protein 7 is expressed in intestinal ER. J. Cell Sci. 119: 943-950.
10. Cohn, J. S. 2008. Are we ready for a prospective study to investigate the role of chylomicrons in cardiovascular disease? Atheroscler. Suppl. 9: 15-18.
11. Zhou, Z., S. Yon Toh, Z. Chen, K. Guo, C. P. Ng, S. Ponniah, S. C. Lin, W. Hong, and P. Li. 2003. Cidea-defi cient mice have lean phenotype and are resistant to obesity. Nat. Genet. 35: 49-56.
12. Xu, L., L. Zhou, and P. Li. 2012. CIDE proteins and lipid metabolism. Arterioscler. Thromb. Vasc. Biol. 32: 1094-1098.
13. Nishino, N., Y. Tamori, S. Tateya, T. Kawaguchi, T. Shibakusa, W. Mizunoya, K. Inoue, R. Kitazawa, S. Kitazawa, Y. Matsuki, et al. 2008. FSP27 contributes to effi cient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J. Clin. Invest. 118: 2808-2821.
14. Toh, S. Y., J. Gong, G. Du, J. Z. Li, S. Yang, J. Ye, H. Yao, Y. Zhang, B. Xue, Q. Li, et al. 2008. Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 defi cient mice. PLoS ONE. 3: e2890.
15. Li, J. Z., J. Ye, B. Xue, J. Qi, J. Zhang, Z. Zhou, Q. Li, Z. Wen, and P. Li. 2007. Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes. 56: 2523-2532.
16. Ye, J., J. Z. Li, Y. Liu, X. Li, T. Yang, X. Ma, Q. Li, Z. Yao, and P. Li. 2009. Cideb, an ER-and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metab. 9: 177-190.
17. Li, X., J. Ye, L. Zhou, W. Gu, E. A. Fisher, and P. Li. 2012. Opposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation. J. Lipid Res. 53: 1877-1889.
18. Li, H., Y. Song, F. Li, L. Zhang, Y. Gu, L. Jiang, W. Dong, J. Ye, and Q. Li. 2010. Identifi cation of lipid droplet-associated proteins in the formation of macrophage-derived foam cells using microarrays. Int. J. Mol. Med. 26: 231-239.
19. Yu, M., H. Wang, J. Zhao, Y. Yuan, C. Wang, J. Li, L. Zhang, Q. Li, and J. Ye. 2013. Expression of CIDE proteins in clear cell renal cell carcinoma and their prognostic signifi cance. Mol. Cell. Biochem. 378: 145-151.
20. Folch, J., M. Lees, and G. H. Sloane Stanley. 1957. A simple method for the isolation and purifi cation of total lipides from animal tissues. J. Biol. Chem. 226: 497-509.
21. Hara, A., and N. S. Radin. 1978. Lipid extraction of tissues with a low-toxicity solvent. Anal. Biochem. 90: 420-426.
22. Drover, V. A., M. Ajmal, F. Nassir, N. O. Davidson, A. M. Nauli, D. Sahoo, P. Tso, and N. A. Abumrad. 2005. CD36 defi ciency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. J. Clin. Invest. 115: 1290-1297.
23. Borensztajn, J., M. S. Rone, and T. J. Kotlar. 1976. The inhibition in vivo of lipoprotein lipase (clearing-factor lipase) activity by triton WR-1339. Biochem. J. 156: 539-543.
24. Levy, E., M. Mehran, and E. Seidman. 1995. Caco-2 cells as a model for intestinal lipoprotein synthesis and secretion. FASEB J. 9: 626-635.
25. Hussain, M. M., R. K. Kancha, Z. Zhou, J. Luchoomun, H. Zu, and A. Bakillah. 1996. Chylomicron assembly and catabolism: role of apolipoproteins and receptors. Biochim. Biophys. Acta. 1300: 151-170.