Hypoxic/ischemic and infectious events have cumulative effects on the risk of cerebral palsy in very-low-birth-weight preterm infants

Neonatology

Volumn 106, Issue 3, 2014, Pages 209-215

  Wang, Lan Wan ^a,e,f   Lin, Yung Chieh ^b,d   Wang, Shan Tair ^c   Yeh, Tsu Fu ^e   Huang, Chao Ching ^d,e  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b Institute of Clinical Medicine   (Taiwan)

^c Department of Gerontology ^*  (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^f KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cerebral palsy; Hypoxia ischemia; Infection; Preterm infants; Very low birth weight

Indexed keywords

ARTICLE; BIRTH WEIGHT; BRAIN DAMAGE; CEREBRAL PALSY; CHRONIC LUNG DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; GESTATIONAL AGE; HEMIPARESIS; HUMAN; HYPOXIA; INFANT; INFECTION; ISCHEMIA; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; NEWBORN PERIOD; NEWBORN SEPSIS; OUTCOME ASSESSMENT; PATENT DUCTUS ARTERIOSUS; PERINATAL PERIOD; PREMATURITY; QUADRIPLEGIA; RESPIRATORY DISTRESS SYNDROME; RESUSCITATION; SEPSIS; SHOCK; VERY LOW BIRTH WEIGHT; ANOXIA; COMPLICATION; DUCTUS ARTERIOSUS, PATENT; INFANT, PREMATURE, DISEASES; LUNG INJURY; NEWBORN; RISK FACTOR;

ANOXIA; CEREBRAL PALSY; DUCTUS ARTERIOSUS, PATENT; FEMALE; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; INFECTION; ISCHEMIA; LUNG INJURY; MALE; RISK FACTORS;

EID: 84903858171     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000362782     Document Type: Article

References (25)

1. Khwaja O, Volpe JJ: Pathogenesis of cerebral white matter injury of prematurity. Arch Dis Child Fetal Neonatal Ed 2008; 93:F153-F161.
2. O'Shea TM: Cerebral palsy in very preterm infants: new epidemiological insights. Ment Retard Dev Disabil Res Rev 2002; 8: 135-145.
3. Vincer MJ, Allen AC, Joseph KS, Stinson DA, Scot H, Wood E: Increasing prevalence of cerebral palsy among very preterm infants: a population-based study. Pediatrics 2006; 118:e1621-e1626.
4. Beaino G, Khoshnood B, Kaminski M, Pierrat V, Marret S, Matis J, Ledesert B, Thiriez G, Fresson J, Roze JC, Zupan-Simunek V, Arnaud C, Burguet A, Larroque B, Breart G, Ancel PV: Predictors of cerebral palsy in very preterm infants: The EPIPAGE prospective population- based cohort study. Dev Med Child Neurol 2010; 52:e119-e125.
5. McElrath TF, Allred EN, Boggess KA, Kuban K, O'Shea TM, Paneth N, Leviton A: Maternal antenatal complications and the risk of neonatal cerebral white matter damage and later cerebral palsy in children born at an extremely low gestational age. Am J Epidemiol 2009; 170: 819-828.
6. Schlapbach LJ, Aebischer M, Adams M, Natalucci G, Bonhoeffer J, Latzin P, Nelle M, Bucher HU, Latal B: Impact of sepsis on neurodevelopmental outcome in a Swiss national cohort of extremely premature infants. Pediatrics 2011; 128:e348-e357.
7. Yanowitz TD, Jordan JA, Gilmour CH, Towbin R, Bowen A, Roberts JM, Brozanski BS: Hemodynamic disturbances in premature infants born after chorioamnionitis: association with cord blood cytokine concentrations. Pediatr Res 2002; 51: 310-316.
8. Wong FY, Silas R, Hew S, Samarasinghe T, Walker AM: Cerebral oxygenation is highly sensitive to blood pressure variability in sick preterm infants. PLoS One 2012; 7:e43165.
9. Kaukola T, Herva R, Perhomma M, Paakko E, Kingsmore S, Vainionpaa L, Hallman M: Population cohort associating chorioamnionitis, cord inflammatory cytokines and neurological outcome in very preterm, extremely low birth weight infants. Pediatr Res 2006; 59: 478-483.
10. Wang LW, Chang YC, Lin CY, Hong JS, Huang CC: Low-dose lipopolysaccharide selectively sensitizes hypoxic ischemia-induced white matter injury in the immature brain. Pediatr Res 2010; 68: 41-47.
11. Wang LW, Wang ST, Huang CC: Preterm infants of educated mothers have better outcome. Acta Paediatr 2008; 97: 568-573.
12. Kuban K, Allred EN, O'Shea M, Paneth N, Pagano M, Leviton A: An algorithm for identifying and classifying cerebral palsy in young children. J Pediatr 2008; 153: 466-472.
13. Schmidt B, Asztalos EV, Roberts RS, Robertson CMT, Sauve RS, Whitfield MF: Impact of bronchopulmonary dysplasia, brain injury and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months. JAMA 2003; 289: 1124-1129.
14. Girard S, Kadhim H, Roy M, Lavoie K, Brochu ME, Larouche A, Sebire G: Role of perinatal inflammation in cerebral palsy. Pediatr Neurol 2009; 40: 168-174.
15. Wyckoff MH, Salhab WA, Heyne RJ, Kendrick DE, Stoll BJ, Laptook AR: Outcome of extremely low birth weight infants who received delivery room cardiopulmonary resuscitation. J Pediatr 2012; 160: 239-244.
16. Gonzalez A, Sosenko IRS, Chandar J, Hummler H, Claure N, Bancalari E: Influence of infection on patent ductus arteriosus and chronic lung disease in premature infants weighing 1, 000 g or less. J Pediatr 1996; 128: 470-478.
17. Chock VY, Ramamoorthy C, Van Meurs KP: Cerebral oxygenation during different treatment strategies for a patent ductus arteriosus. Neonatology 2011; 100: 233-240.
18. Bose CL, Laughon MM, Allred EN, O'Shea TM, Van Marter LJ, Ehrenkranz RA, Fichorova RN, Leviton A: Systemic inflammation associated with mechanical ventilation among extremely preterm infants. Cytokine 2013; 61: 315-322.
19. Bassler D, Stoll BJ, Schmidt B, Asztalos EV, Roberts RS, Robertson CMT, Sauve RS: Using a count of neonatal morbidities to predict poor outcome in extremely low birth weight infants: added role of neonatal infection. Pediatrics 2009; 123: 313-318.
20. Martin RJ, Wang K, Koroglu O, Di-Fiore J, Kc P: Intermittent hypoxic episodes in preterm infants: do they matter? Neonatology 2011; 100: 303-310.
21. Van Marter LJ, Dammann O, Allred EN, Leviton A, Pagano M, Moore M, Martin C: Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants. J Pediatr 2002; 140: 171-176.
22. Shim SY, Jeong HJ, Son DW, Jeong JS, Oh SH, Park SY, Ryu TH, Kim YB, Cho ZH: Altered microstructure of white matter except the corpus callosum is independent of prematurity. Neonatology 2012; 102: 309-315.
23. Oskoui M, Coutinho F, Dykeman J, Jette N, Pringsheim T: An update on the prevalence of cerebral palsy: a systemic review and metaanalysis. Dev Med Child Neurol 2013; 55: 509- 519.
24. Farooqi A, Hagglof B, Sedin G, Serenius F: Impact at age 11 years of major neonatal morbidities in children born extremely preterm. Pediatrics 2011; 127:e1247-e1257.
25. Doyle LW, Anderson PJ: Pulmonary and neurological follow-up of extremely preterm infants. Neonatology 2010; 97: 388-394.