PARP-1 hyperactivation and reciprocal elevations in intracellular Ca2+ during ROS-induced nonapoptotic cell death

Toxicological Sciences

Volumn 140, Issue 1, 2014, Pages 118-134

  Zhang, Fengjiao ^a   Xie, Ruiye ^a,b   Munoz, Frances M ^a   Lau, Serrine S ^a   Monks, Terrence J ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

2,3,5 tris(glutathion S yl)hydroquinone; Apoptosis inducing factor; HK 2 cells; Poly(ADP ribose)polymerase 1; Reactive oxygen species

Indexed keywords

2,3,5 TRIS(GLUTATHION S YL)HYDROQUINONE; APOPTOSIS INDUCING FACTOR; CALCIUM ION; CASPASE 3; CISPLATIN; HISTONE H2AX; HYDROQUINONE DERIVATIVE; LIPOCORTIN 5; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLY(ADENOSINE DIPHOSPHATE RIBOSE); REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 2,3,5-(TRIGLUTATHION-S-YL)HYDROQUINONE; CALCIUM; GLUTATHIONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, HUMAN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ADULT; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CHELATION; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DNA STRAND BREAKAGE; ENZYME ACTIVATION; EPITHELIUM CELL; FLOW CYTOMETRY; GENOTOXICITY; HL 60 CELL LINE; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; KIDNEY PROXIMAL TUBULE; NONHUMAN; RAT; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; CELL LINE; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECTS; METABOLISM; PATHOLOGY; TOXICITY;

CALCIUM; CELL CULTURE TECHNIQUES; CELL DEATH; CELL LINE; CELL SURVIVAL; EPITHELIAL CELLS; GLUTATHIONE; HUMANS; HYDROQUINONES; KIDNEY TUBULES, PROXIMAL; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES;

EID: 84903846851     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu073     Document Type: Article

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