ROS1 translocations and amplifications in lung cancer brain metastases

Journal of Neuro-Oncology

Volumn 118, Issue 2, 2014, Pages 425-426

  Preusser, Matthias ^a   Streubel, Berthold ^a   Birner, Peter ^a,b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSQUAMOUS CARCINOMA; AUSTRIA; BRAIN METASTASIS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE TRANSLOCATION; HUMAN; HUMAN TISSUE; LARGE CELL CARCINOMA; LETTER; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; ROS1 GENE; BRAIN TUMOR; GENETICS; LUNG TUMOR; PATHOLOGY; SECONDARY;

ONCOPROTEIN; PROTEIN TYROSINE KINASE; ROS1 PROTEIN, HUMAN;

BRAIN NEOPLASMS; GENE AMPLIFICATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LUNG NEOPLASMS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; TRANSLOCATION, GENETIC;

EID: 84903839741     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-014-1446-x     Document Type: Letter

References (3)

1. Davies KD, Doebele RC (2013) Molecular pathways: ROS1 fusion proteins in cancer. Clin Cancer Res 19:4040-4045
2. Bergethon K, Shaw AT, Ou SH, Katayama R, Lovly CM, McDonald NT, Massion PP, Siwak-Tapp C, Gonzalez A, Fang R, Mark EJ, Batten JM, Chen H, Wilner KD, Kwak EL, Clark JW, Carbone DP, Ji H, Engelman JA, Mino-Kenudson M, Pao W, Iafrate AJ (2012) ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol 30:863-870
3. Preusser M, Berghoff AS, Ilhan-Mutlu A, Magerle M, Dinhof C, Widhalm G, Dieckmann K, Marosi C, Wohrer A, Hackl M, Zochbauer-Muller S, von Deimling A, Schoppmann SF, Zielinski CC, Streubel B, Birner P (2013) ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer. Lung Cancer 80:278-283