Functionalization, cyclization and antiviral activity of A-secotriterpenoids

European Journal of Medicinal Chemistry

Volumn 83, Issue , 2014, Pages 601-608

  Grishko, Victoria V ^a   Galaiko, Natalia V ^a   Tolmacheva, Irina A ^a   Kucherov, Igor I ^b   Eremin, Vladimir F ^b   Boreko, Eugene I ^b   Savinova, Olga V ^b   Slepukhin, Pavel A ^c  

^a INSTITUTE OF TECHNICAL CHEMISTRY   (Russian Federation)

^b Republican Research and Practical Center for Epidemiology and Microbiology   (Belarus)

^c INSTITUTE OF ORGANIC SYNTHESIS   (Russian Federation)

Author keywords

18 H Glycyrrhetinic acid; A secotriterpenoids; Antiviral activity; Betulin; HIV 1; Influenza virus; Nitrile anion cyclizations

Indexed keywords

2,3 SECOLUPANE C3 ALDOXIME; ALDOXIME; ANTIVIRUS AGENT; LUPANE KETOXIME; NITRILE; OXIME; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; 1 CYANO 19BETA,28 EPOXY 2 NOR 18ALPHAH OLEAN 1(3) ENE; 3 AMINO 1 CYANO 19BETA,28 EPOXY 2 NOR 18ALPHAH OLEAN 1(3) ENE; 3 HYDROXYIMINO 1 CYANO 19BETA,28 EPOXY 2,3 SECO 2 NOR 18ALPHAH OLEANANE; 3 HYDROXYIMINO 1 CYANO 2,3 SECO 2 NORLUP 20(29) ENE 28 OIC ACID; METHYL 1 CYANO 2 NORLUP 1(3),20(29) DIENE 28 OATE; METHYL 3 AMINO 1 CYANO 2 NORLUP 1(3),20(29) DIENE 28 OATE; METHYL 3 HYDROXYIMINO 1 CYANO 11 OXO 2,3 SECO 2 NOR 18BETAH OLEAN 12(13) ENE 30 OATE; METHYL 3 HYDROXYIMINO 1 CYANO 2,3 SECO 2 NORLUP 20(29)ENE 28 OATE; TERPENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; INFLUENZA VIRUS A; INFLUENZA VIRUS A H7N1; NONHUMAN; X RAY DIFFRACTION; VIRUS ENVELOPE; VIRUS REPLICATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECTS;

ANTIVIRAL AGENTS; CYCLIZATION; HIV-1; INFLUENZA A VIRUS, H7N1 SUBTYPE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OXIMES; TERPENES;

EID: 84903835090     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.12.058     Document Type: Article

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