Influence of Alzheimer's disease genes on cognitive decline: The Guangzhou Biobank Cohort Study

Neurobiology of Aging

Volumn 35, Issue 10, 2014, Pages 2422.e3-2422.e8

  Gui, Hongsheng ^a   Jiang, Chao Qiang ^b   Cherny, Stacey S ^a,c,d   Sham, Pak Chung ^a,c,d   Xu, Lin ^a   Liu, Bin ^b   Jin, Ya Li ^b   Zhu, Tong ^b   Zhang, Wei Sen ^b   Thomas, G Neil ^e   Cheng, Kar Keung ^e   Lam, Tai Hing ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b Guangzhou No 12 Hospital   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

ACE; Alzheimer's disease; APOE; Cognitive decline; Joint effect

Indexed keywords

APOLIPOPROTEIN E4; DIPEPTIDYL CARBOXYPEPTIDASE;

ACE GENE; ADULT; ALZHEIMER DISEASE; ARTICLE; CHINA; CHINESE; COGNITIVE DEFECT; COHORT ANALYSIS; CONTROLLED STUDY; EDUCATIONAL STATUS; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; COGNITION; GENETIC PREDISPOSITION; GENETICS; PSYCHOLOGY;

AGED; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; ASIAN CONTINENTAL ANCESTRY GROUP; COGNITION; COHORT STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84903818255     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.04.022     Document Type: Article

References (45)

1. Au Yeung S.L., Jiang C., Zhang W., Lam T.H., Cheng K.K., Leung G.M., Schooling C.M. Moderate alcohol use and cognitive function in the Guangzhou Biobank Cohort study. Ann. Epidemiol. 2010, 20:873-882.
2. Barral S., Bird T., Goate A., Farlow M.R., Diaz-Arrastia R., Bennett D.A., Graff-Radford N., Boeve B.F., Sweet R.A., Stern Y., Wilson R.S., Foroud T., Ott J., Mayeux R., National Institute on Aging Late-Onset Alzheimer's Disease Genetics Study Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory. Neurology 2012, 78:1464-1471.
3. Bertram L., Lange C., Mullin K., Parkinson M., Hsiao M., Hogan M.F., Schjeide B.M., Hooli B., Divito J., Ionita I., Jiang H., Laird N., Moscarillo T., Ohlsen K.L., Elliott K., Wang X., Hu-Lince D., Ryder M., Murphy A., Wagner S.L., Blacker D., Becker K.D., Tanzi R.E. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am. J. Hum. Genet. 2008, 83:623-632.
4. Bertram L., McQueen M.B., Mullin K., Blacker D., Tanzi R.E. Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat. Genet. 2007, 39:17-23.
5. Boker S., Neale M., Maes H., Wilde M., Spiegel M., Brick T., Spies J., Estabrook R., Kenny S., Bates T., Mehta P., Fox J. OpenMx: an open source extended structural equation modeling framework. Psychometrika 2011, 76:306-317.
6. Chen L.H., Kao P.Y., Fan Y.H., Ho D.T., Chan C.S., Yik P.Y., Ha J.C., Chu L.W., Song Y.Q. Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer's disease in a southern Chinese population. Neurobiol. Aging 2012, 33:210.e1-210.e7.
7. Cherbuin N., Reglade-Meslin C., Kumar R., Jacomb P., Easteal S., Christensen H., Sachdev P., Anstey K.J. Risk factors of transition from normal cognition to mild cognitive disorder: the PATH through Life Study. Dement Geriatr. Cogn. Disord. 2009, 28:47-55.
8. Christensen H., Batterham P.J., Mackinnon A.J., Jorm A.F., Mack H.A., Mather K.A., Anstey K.J., Sachdev P.S., Easteal S. The association of APOE genotype and cognitive decline in interaction with risk factors in a 65-69 year old community sample. BMC Geriatr. 2008, 8:14.
9. Daviglus M.L., Bell C.C., Berrettini W., Bowen P.E., Connolly E.S., Cox N.J., Dunbar-Jacob J.M., Granieri E.C., Hunt G., McGarry K., Patel D., Potosky A.L., Sanders-Bush E., Silberberg D., Trevisan M. National Institutes of Health State-of-the-Science Conference statement: preventing Alzheimer disease and cognitive decline. Ann. Intern. Med. 2010, 153:176-181.
10. De Jager P.L., Shulman J.M., Chibnik L.B., Keenan B.T., Raj T., Wilson R.S., Yu L., Leurgans S.E., Tran D., Aubin C., Anderson C.D., Biffi A., Corneveaux J.J., Huentelman M.J., Alzheimer's Disease Neuroimaging Initiative, Rosand J., Daly M.J., Myers A.J., Reiman E.M., Bennett D.A., Evans D.A. Agenome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol. Aging 2012, 33:1017.e1-1017.e15.
11. DeCarli C. Mild cognitive impairment: prevalence, prognosis, aetiology, and treatment. Lancet Neurol. 2003, 2:15-21.
12. Devore E.E., Kang J.H., Okereke O., Grodstein F. Physical activity levels and cognition in women with type 2 diabetes. Am. J. Epidemiol. 2009, 170:1040-1047.
13. Dik M.G., Deeg D.J., Bouter L.M., Corder E.H., Kok A., Jonker C. Stroke and apolipoprotein E epsilon4 are independent risk factors for cognitive decline: a population-based study. Stroke 2000, 31:2431-2436.
14. Duron E., Hanon O. Vascular risk factors, cognitive decline, and dementia. Vasc. Health Risk Manag. 2008, 4:363-381.
15. Ferri C.P., Prince M., Brayne C., Brodaty H., Fratiglioni L., Ganguli M., Hall K., Hasegawa K., Hendrie H., Huang Y., Jorm A., Mathers C., Menezes P.R., Rimmer E., Scazufca M., Alzheimer's Disease International Global prevalence of dementia: a Delphi consensus study. Lancet 2005, 366:2112-2117.
16. Hadjadj S., Tarnow L., Forsblom C., Kazeem G., Marre M., Groop P.H., Parving H.H., Cambien F., Tregouet D.A., Gut I.G., Theva A., Gauguier D., Farrall M., Cox R., Matsuda F., Lathrop M., Hager-Vionnet N., Group E.S. Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations. J.Am. Soc. Nephrol. 2007, 18:1284-1291.
17. Harold D., Abraham R., Hollingworth P., Sims R., Gerrish A., Hamshere M.L., Pahwa J.S., Moskvina V., Dowzell K., Williams A., Jones N., Thomas C., Stretton A., Morgan A.R. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat. Genet. 2009, 41:1088-1093.
18. Heys M., Jiang C., Schooling C.M., Zhang W., Cheng K.K., Lam T.H., Leung G.M. Is childhood meat eating associated with better later adulthood cognition in a developing population?. Eur. J. Epidemiol. 2010, 25:507-516.
19. Heys M., Schooling C.M., Jiang C., Adab P., Cheng K.K., Lam T.H., Leunga G.M. Childhood growth and adulthood cognition in a rapidly developing population. Epidemiology 2009, 20:91-99.
20. Hu X., Pickering E., Liu Y.C., Hall S., Fournier H., Katz E., Dechairo B., John S., Van Eerdewegh P., Soares H., Alzheimer's Disease Neuroimaging Initiative Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease. PLoS One 2011, 6:e16616. 10.1371/journal.pone.0016616.
21. Hu X., Pickering E., Liu Y.C., Hall S., Fournier H., Katz E., Dechairo B., John S., Van Eerdewegh P., Soares H., Alzheimer's Disease Neuroimaging Initiative Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease. PLoS One 2011, 6:e16616. [Electronic Resource].
22. Jacobson A.M., Paterson A.D., Ryan C.M., Cleary P.A., Waberski B.H., Weinger K., Musen G., Dahms W., Bayless M., Silvers N., Harth J., Boright A.P., DCCT/EDIC Research Group The associations of apolipoprotein E and angiotensin-converting enzyme polymorphisms and cognitive function in Type 1 diabetes based on an 18-year follow-up of the DCCT cohort. Diabet. Med. 2010, 27:15-22.
23. Jiang C., Thomas G.N., Lam T.H., Schooling C.M., Zhang W., Lao X., Adab P., Liu B., Leung G.M., Cheng K.K. Cohort profile: The Guangzhou Biobank Cohort Study, a Guangzhou-Hong Kong-Birmingham collaboration. Int. J. Epidemiol. 2006, 35:844-852.
24. Jonsson T., Stefansson H., Steinberg S., Jonsdottir I., Jonsson P.V., Snaedal J., Bjornsson S., Huttenlocher J., Levey A.I., Lah J.J., Rujescu D., Hampel H., Giegling I., Andreassen O.A., Engedal K., Ulstein I., Djurovic S., Ibrahim-Verbaas C., Hofman A., Ikram M.A., van Duijn C.M., Thorsteinsdottir U., Kong A., Stefansson K. Variant of TREM2 associated with the risk of Alzheimer's disease. N.Engl. J. Med. 2013, 368:107-116.
25. Kamboh M.I., Demirci F.Y., Wang X., Minster R.L., Carrasquillo M.M., Pankratz V.S., Younkin S.G., Saykin A.J., Alzheimer's Disease Neuroimaging Initiative, Jun G., Baldwin C., Logue M.W., Buros J., Farrer L., Pericak-Vance M.A., Haines J.L., Sweet R.A., Ganguli M., Feingold E., Dekosky S.T., Lopez O.L., Barmada M.M. Genome-wide association study of Alzheimer's disease. Transl. Psychiatry 2012, 2:e117.
26. Lam L.C., Tam C.W., Lui V.W., Chan W.C., Chan S.S., Wong S., Wong A., Tham M.K., Ho K.S., Chan W.M., Chiu H.F. Prevalence of very mild and mild dementia in community-dwelling older Chinese people in Hong Kong. Int. Psychogeriatr. 2008, 20:135-148.
27. Lambert J.C., Heath S., Even G., Campion D., Sleegers K., Hiltunen M., Combarros O., Zelenika D., Bullido M.J., Tavernier B., Letenneur L., Bettens K., Berr C., Pasquier F., Fievet N., Barberger-Gateau P., Engelborghs S., De Deyn P., Mateo I., Franck A., Helisalmi S., Porcellini E., Hanon O., European Alzheimer's Disease Initiative Initiative, de Pancorbo M.M., Lendon C., Dufouil C., Jaillard C., Leveillard T., Alvarez V., Bosco P., Mancuso M., Panza F., Nacmias B., Bossu P., Piccardi P., Annoni G., Seripa D., Galimberti D., Hannequin D., Licastro F., Soininen H., Ritchie K., Blanche H., Dartigues J.F., Tzourio C., Gut I., Van Broeckhoven C., Alperovitch A., Lathrop M., Amouyel P. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat. Genet. 2009, 41:1094-1099.
28. LeBlanc M., Kulle B., Sundet K., Agartz I., Melle I., Djurovic S., Frigessi A., Andreassen O.A. Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function. J.Psychiatr. Res. 2012, 46:271-278.
29. Lee S., Kawachi I., Berkman L.F., Grodstein F. Education, other socioeconomic indicators, and cognitive function. Am. J. Epidemiol. 2003, 157:712-720.
30. Lee T., Henry J.D., Trollor J.N., Sachdev P.S. Genetic influences on cognitive functions in the elderly: a selective review of twin studies. Brain Res. Rev. 2010, 64:1-13.
31. Liu X., Yue C., Xu Z., Shu H., Pu M., Yu H., Shi Y., Zhuang L., Xu X., Zhang Z. Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population. PLoS One 2012, 7:e41198.
32. Ning M., Yang Y., Zhang Z., Chen Z., Zhao T., Zhang D., Zhou D., Xu J., Liu Z., Wang Y., Liu Y., Zhao X., Li W., Li S., He L. Amyloid-beta-related genes SORL1 and ACE are genetically associated with risk for late-onset Alzheimer disease in the Chinese population. Alzheimer Dis. Assoc. Disord 2010, 10.1097/WAD.0b013e3181e6a575.
33. Prince M., Acosta D., Chiu H., Scazufca M., Varghese M., 10/66 Dementia Research Group Dementia diagnosis in developing countries: a cross-cultural validation study. Lancet 2003, 361:909-917.
34. Purcell S., Neale B., Todd-Brown K., Thomas L., Ferreira M.A., Bender D., Maller J., Sklar P., de Bakker P.I., Daly M.J., Sham P.C. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 2007, 81:559-575.
35. Seeman T.E., Huang M.H., Bretsky P., Crimmins E., Launer L., Guralnik J.M. Education and APOE-e4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging. J.Gerontol. B Psychol. Sci. Soc. Sci. 2005, 60:P74-P83.
36. Sherva R., Tripodis Y., Bennett D.A., Chibnik L.B., Crane P.K., de Jager P.L., Farrer L.A., Saykin A.J., Shulman J.M., Naj A., Green R.C., GENAROAD Consortium, Alzheimer's Disease Neuroimaging Initiative, Alzheimer's Disease Genetics Consortium Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014, 10:45-52.
37. Sleegers K., Lambert J.C., Bertram L., Cruts M., Amouyel P., Van Broeckhoven C. The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects. Trends Genet. 2010, 26:84-93.
38. Song F., Poljak A., Crawford J., Kochan N.A., Wen W., Cameron B., Lux O., Brodaty H., Mather K., Smythe G.A., Sachdev P.S. Plasma apolipoprotein levels are associated with cognitive status and decline in a community cohort of older individuals. PLoS One 2012, 7:e34078.
39. Stewart R., Powell J., Prince M., Mann A. ACE genotype and cognitive decline in an African-Caribbean population. Neurobiol. Aging 2004, 25:1369-1375.
40. Sweet R.A., Seltman H., Emanuel J.E., Lopez O.L., Becker J.T., Bis J.C., Weamer E.A., DeMichele-Sweet M.A., Kuller L.H. Effect of Alzheimer's disease risk genes on trajectories of cognitive function in the Cardiovascular Health Study. Am. J. Psychiatry 2012, 169:954-962.
41. Takeda S., Sato N., Ogihara T., Morishita R. The renin-angiotensin system, hypertension and cognitive dysfunction in Alzheimer's disease: new therapeutic potential. Front. Biosci. 2008, 13:2253-2265.
42. Welsh K.A., Butters N., Mohs R.C., Beekly D., Edland S., Fillenbaum G., Heyman A. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery. Neurology 1994, 44:609-614.
43. Xu, L., Jiang, C.Q., Lam, T.H., Zhang, W., Cherny, S.S., Thomas, G.N., Cheng, K.K., 2014. Sleep duration and memory in the elderly Chinese: longitudinal analysis of the Guangzhou Biobank Cohort Study. Sleep (accepted).
44. Xu L., Jiang C.Q., Lam T.H., Liu B., Jin Y.L., Zhu T., Zhang W.S., Cheng K.K., Thomas G.N. Short or long sleep duration is associated with memory impairment in older Chinese: the Guangzhou Biobank Cohort Study. Sleep 2011, 34:575-580.
45. Yatani, K. Statistics for HCI Research: Logistic Regression. Available at: http://yatani.jp/HCIstats/LogisticRegression. Accessed May 16, 2014.