Risk of retinal tear or detachment with oral fluoroquinolone use: A cohort study

Pharmacoepidemiology and Drug Safety

Volumn 23, Issue 7, 2014, Pages 745-752

  Eftekhari, Kian ^a   Ghodasra, Devon H ^a   Haynes, Kevin ^b   Chen, Jinbo ^b   Kempen, John H ^a,b   Vanderbeek, Brian L ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cohort; Cox regression; Fluoroquinolones; Pharmacoepidemiology; Retinal break; Retinal detachment; Retinal tear

Indexed keywords

BETA LACTAM ANTIBIOTIC; CIPROFLOXACIN; LEVOFLOXACIN; NORFLOXACIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; ANTIINFECTIVE AGENT; QUINOLONE DERIVATIVE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; COHORT ANALYSIS; ENDOPHTHALMITIS; EYE SURGERY; FEMALE; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PHARMACOEPIDEMIOLOGY; PRESCRIPTION; PRIORITY JOURNAL; RETINA DETACHMENT; RETINA TEAR; RETROSPECTIVE STUDY; COMPARATIVE STUDY; FACTUAL DATABASE; INFANT; MIDDLE AGED; MULTIVARIATE ANALYSIS; ORAL DRUG ADMINISTRATION; PROPORTIONAL HAZARDS MODEL; RETINAL DETACHMENT; RETINAL PERFORATIONS; RISK; TIME; VERY ELDERLY; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; CHILD; COHORT STUDIES; DATABASES, FACTUAL; FEMALE; FLUOROQUINOLONES; HUMANS; INFANT; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODELS; RETINAL DETACHMENT; RETINAL PERFORATIONS; RETROSPECTIVE STUDIES; RISK; TIME FACTORS; YOUNG ADULT;

EID: 84903814613     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.3623     Document Type: Article

References (22)

1. Linder JA, Huang ES, Steinman MA, Gonzales R, Stafford RS. Fluoroquinolone prescribing in the United States: 1995 to 2002. Am J Med 2005; 118: 259-268.
2. Etminan M, Forooghian F, Brophy JM, Bird ST, Maberley D. Oral fluoroquinolones and the risk of retinal detachment. JAMA 2012; 307(13): 1414-1419.
3. Kuo SC, Chen YT, Lee YT, et al. Association between recent use of fluoroquinolones and rhegmatogenous retinal detachment: a population-based cohort study. Clin Infect Dis 2014; 58(2): 197-203.
4. Pasternak B, Svanström H, Melbye M, Hviid A. Association between fluoroquinolone use and retinal detachment. JAMA 2013; 310(20): 2184-2190.
5. Nowroozzadeh MH. Retinal detachment and fluoroquinolones [letter]. JAMA 2012; 308(3): 233.
6. Rao RC, Dlouhy BJ. Retinal detachment and fluoroquinolones [letter]. JAMA 2012; 308(3): 233-234.
7. Aristodemou P, Stylianides AC. Retinal detachment and fluoroquinolones [letter]. JAMA 2012; 308(3): 234.
8. Molloy AC, Mitry D. Retinal detachment and fluoroquinolones [letter]. JAMA 2012; 308(3): 234-235.
9. Etminan M, Brophy JM, Maberley D. Retinal detachment and fluoroquinolones [letter]. JAMA 2012; 308(3): 235.
10. Albini TA, Karakousis PC, Abbey AM, et al. Association between oral fluoroquinolones and retinal detachment [editorial]. Am J Ophthalmol 2012; 154(6): 919-921.
11. Han DP, Szabo A. Flashes, floaters, and oral fluoroquinolones: is retinal detachment a worry? JAMA Ophthalmol 2013; 131(1): 91-93.
12. Schwartz SG, Flynn HW, Jr, Mieler WF. Update on retinal detachment surgery. Curr Opin Ophthalmol 2013; 24: 255-261.
13. Brett A. Oral Fluoroquinolone Use and Retinal Detachment Reconciling Conflicting Findings in Observational Research. JAMA 2013; 310(20): 2151-2152.
14. Chang DF, Braga-Mele R, Mamalis N, et al. Prophylaxis of postoperative endophthalmitis after cataract surgery: results of the 2007 ASCRS member survey. J Cataract Refract Surg 2007; 33(10): 1801-1805.
15. Al-Amri AM. Corneal perforation associated with topically applied gatifloxacin. Cornea 2008; 27(3): 370-371.
16. Samarakoon N, Harrisberg B, Ell J. Ciprofloxacin-induced toxic optic neuropathy. Clin Experiment Ophthalmol 2007; 35(1): 102-104.
17. Rampal S, Kaur R, Sethi R, et al. Ofloxacin-associated retinopathy in rabbits: role of oxidative stress. Hum Exp Toxicol 2008; 27(5): 409-415.
18. Blak BT, Thompson M, Dattani H, et al. Generalisability of The Health Improvement Network (THIN) database: demographics, chronic disease prevalence and mortality rates. Inform Prim Care 2011; 19(4): 251-255.
19. Yonemoto J, Ideta H, Sasaki K, et al. The age of onset of posterior vitreous detachment. Graefes Arch Clin Exp Ophthalmol 1994; 232: 67-70.
20. Johnson MW. Posterior vitreous detachment: evolution and complications of its early stages. Am J Ophthalmol 2010; 149: 371-382.
21. Lin DY, Wei LJ. The robust inference for the Cox proportional hazards model. J Am Stat Assoc 1989; 84(408): 1074-1078.
22. http://dictionary.reference.com/browse/rhegma [July 2013].