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Volumn 60, Issue 3, 2014, Pages 238-245

Improvements of vaginal atrophy without systemic side effects after topical application of Pueraria mirifica, a phytoestrogen-rich herb, in postmenopausal cynomolgus macaques

Author keywords

Menopause; Phytoestrogens; Sex skin color; Vaginal dryness

Indexed keywords

PHYTOESTROGEN; PLANT EXTRACT;

EID: 84903788654     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.2013-144     Document Type: Article
Times cited : (11)

References (55)
  • 1
    • 0034739104 scopus 로고    scopus 로고
    • Oestrogens and lower urinary tract function
    • [Medline] [CrossRef]
    • Hextall A. Oestrogens and lower urinary tract function. Maturitas 2000; 36: 83-92. [Medline] [CrossRef]
    • (2000) Maturitas , vol.36 , pp. 83-92
    • Hextall, A.1
  • 2
    • 0030008779 scopus 로고    scopus 로고
    • Prevalence of genitourinary and other climacteric symptoms in 61-year-old women
    • [Medline] [CrossRef]
    • Stenberg A, Heimer G, Ulmsten U, Cnattingius S. Prevalence of genitourinary and other climacteric symptoms in 61-year-old women. Maturitas 1996; 24: 31-36. [Medline] [CrossRef]
    • (1996) Maturitas , vol.24 , pp. 31-36
    • Stenberg, A.1    Heimer, G.2    Ulmsten, U.3    Cnattingius, S.4
  • 3
    • 0034658676 scopus 로고    scopus 로고
    • Diagnosis and treatment of atrophic vaginitis
    • [Medline]
    • Bachmann GA, Nevadunsky NS. Diagnosis and treatment of atrophic vaginitis. Am Fam Physician 2000; 61: 3090-3096. [Medline]
    • (2000) Am Fam Physician , vol.61 , pp. 3090-3096
    • Bachmann, G.A.1    Nevadunsky, N.S.2
  • 4
    • 39049177825 scopus 로고    scopus 로고
    • Local oestrogen for vaginal atrophy in postmenopausal women
    • [Medline]
    • Suckling J, Lethaby A, Kennedy R. Local oestrogen for vaginal atrophy in postmenopausal women. Cochrane Database Syst Rev 2006; 18: CD001500. [Medline]
    • (2006) Cochrane Database Syst Rev , vol.18
    • Suckling, J.1    Lethaby, A.2    Kennedy, R.3
  • 5
    • 70350468734 scopus 로고    scopus 로고
    • Vaginal estrogen therapy for the treatment of atrophic vaginitis
    • [Medline] [CrossRef]
    • Lynch C. Vaginal estrogen therapy for the treatment of atrophic vaginitis. J Womens Health (Larchmt) 2009; 18: 1595-1606. [Medline] [CrossRef]
    • (2009) J Womens Health (Larchmt) , vol.18 , pp. 1595-1606
    • Lynch, C.1
  • 6
    • 61949094584 scopus 로고    scopus 로고
    • Topical estrogen therapy in the management of postmenopausal vaginal atrophy: An up-to-date overview
    • [Medline] [CrossRef]
    • Al-Baghdadi O, Ewies AA. Topical estrogen therapy in the management of postmenopausal vaginal atrophy: an up-to-date overview. Climacteric 2009; 12: 91-105. [Medline] [CrossRef]
    • (2009) Climacteric , vol.12 , pp. 91-105
    • Al-Baghdadi, O.1    Ewies, A.A.2
  • 7
    • 27144541559 scopus 로고    scopus 로고
    • Botanical and dietary supplements for menopausal symptoms: What works, what does not
    • [Medline] [CrossRef]
    • Geller SE, Studee L. Botanical and dietary supplements for menopausal symptoms: what works, what does not. J Womens Health (Larchmt) 2005; 14: 634-649. [Medline] [CrossRef]
    • (2005) J Womens Health (Larchmt) , vol.14 , pp. 634-649
    • Geller, S.E.1    Studee, L.2
  • 8
    • 84862247275 scopus 로고    scopus 로고
    • Medical applications of phytoestrogens from the Thai herb Pueraria mirifica
    • [Medline] [CrossRef]
    • Malaivijitnond S. Medical applications of phytoestrogens from the Thai herb Pueraria mirifica. Fr Medecine 2012; 6: 8-21. [Medline] [CrossRef]
    • (2012) Fr Medecine , vol.6 , pp. 8-21
    • Malaivijitnond, S.1
  • 9
    • 34248369803 scopus 로고    scopus 로고
    • Evaluation of the estrogenic activity of the wild Pueraria mirifica by vaginal cornification assay
    • [Medline] [CrossRef]
    • Cherdshewasart W, Kitsamai Y, Malaivijitnond S. Evaluation of the estrogenic activity of the wild Pueraria mirifica by vaginal cornification assay. J Reprod Dev 2007; 53: 385-393. [Medline] [CrossRef]
    • (2007) J Reprod Dev , vol.53 , pp. 385-393
    • Cherdshewasart, W.1    Kitsamai, Y.2    Malaivijitnond, S.3
  • 10
    • 12444332031 scopus 로고    scopus 로고
    • Different effects of Pueraria mirifica, a herb containing phytoestrogens, on LH and FSH secretion in gonadectomized female and male rats
    • [Medline] [CrossRef]
    • Malaivijitnond S, Kiatthaipipat P, Cherdshewasart W, Watanabe G, Taya K. Different effects of Pueraria mirifica, a herb containing phytoestrogens, on LH and FSH secretion in gonadectomized female and male rats. J Pharmacol Sci 2004; 96: 428-435. [Medline] [CrossRef]
    • (2004) J Pharmacol Sci , vol.96 , pp. 428-435
    • Malaivijitnond, S.1    Kiatthaipipat, P.2    Cherdshewasart, W.3    Watanabe, G.4    Taya, K.5
  • 11
    • 33748518929 scopus 로고    scopus 로고
    • Using vaginal cytology to assess the estrogenic activity of phytoestrogen-rich herb
    • [Medline] [CrossRef]
    • Malaivijitnond S, Chansri K, Kijkuokul P, Urasopon N, Cherdshewasart W. Using vaginal cytology to assess the estrogenic activity of phytoestrogen-rich herb. J Ethnopharmacol 2006; 107: 354-360. [Medline] [CrossRef]
    • (2006) J Ethnopharmacol , vol.107 , pp. 354-360
    • Malaivijitnond, S.1    Chansri, K.2    Kijkuokul, P.3    Urasopon, N.4    Cherdshewasart, W.5
  • 13
    • 34948886075 scopus 로고    scopus 로고
    • Effect of Pueraria mirifica on vaginal health
    • [Medline] [CrossRef]
    • Manonai J, Chittacharoen A, Theppisai U, Theppisai H. Effect of Pueraria mirifica on vaginal health. Menopause 2007; 14: 919-924. [Medline] [CrossRef]
    • (2007) Menopause , vol.14 , pp. 919-924
    • Manonai, J.1    Chittacharoen, A.2    Theppisai, U.3    Theppisai, H.4
  • 14
    • 58649105152 scopus 로고    scopus 로고
    • Isoflavone content of rodent diets and its estrogenic effect on vaginal cornification in Pueraria mirificatreated rats
    • [CrossRef]
    • Urasopon N, Hamada Y, Asaoka K, Poungmali U, Malaivijitnond S. Isoflavone content of rodent diets and its estrogenic effect on vaginal cornification in Pueraria mirificatreated rats. Sci Asia 2008; 34: 371-376. [CrossRef]
    • (2008) Sci Asia , vol.34 , pp. 371-376
    • Urasopon, N.1    Hamada, Y.2    Asaoka, K.3    Poungmali, U.4    Malaivijitnond, S.5
  • 15
    • 0031892063 scopus 로고    scopus 로고
    • The effects of delayed hormone replacement therapy on estrogen receptors of the cynomolgus monkey bladder and vagina
    • [Medline] [CrossRef]
    • Robinson D, Register TC, Carter LR. The effects of delayed hormone replacement therapy on estrogen receptors of the cynomolgus monkey bladder and vagina. Neurourol Urodyn 1998; 17: 241-247. [Medline] [CrossRef]
    • (1998) Neurourol Urodyn , vol.17 , pp. 241-247
    • Robinson, D.1    Register, T.C.2    Carter, L.R.3
  • 16
    • 33751521711 scopus 로고    scopus 로고
    • Hormonal activity of combinations of genistein, bisphenol A and 17β-estradiol in the female Wistar rat
    • [Medline] [CrossRef]
    • Schmidt S, Degen GH, Seibel J, Hertrampf T, Vollmer G, Diel P. Hormonal activity of combinations of genistein, bisphenol A and 17β-estradiol in the female Wistar rat. Arch Toxicol 2006; 80: 839-845. [Medline] [CrossRef]
    • (2006) Arch Toxicol , vol.80 , pp. 839-845
    • Schmidt, S.1    Degen, G.H.2    Seibel, J.3    Hertrampf, T.4    Vollmer, G.5    Diel, P.6
  • 17
    • 77958187739 scopus 로고    scopus 로고
    • The effect of hormonal status on the expression of estrogen and progesterone receptor in vaginal wall and periurethral tissue in urogynecological patients
    • [Medline] [CrossRef]
    • Skala CE, Petry IB, Albrich SB, Puhl A, Naumann G, Koelbl H. The effect of hormonal status on the expression of estrogen and progesterone receptor in vaginal wall and periurethral tissue in urogynecological patients. Eur J Obstet Gynecol Reprod Biol 2010; 153: 99-103. [Medline] [CrossRef]
    • (2010) Eur J Obstet Gynecol Reprod Biol , vol.153 , pp. 99-103
    • Skala, C.E.1    Petry, I.B.2    Albrich, S.B.3    Puhl, A.4    Naumann, G.5    Koelbl, H.6
  • 19
    • 1042279610 scopus 로고    scopus 로고
    • Estrogenic effects of Pueraria mirifica on the menstrual cycle and hormone-related ovarian functions in cyclic female cynomolgus monkeys
    • [Medline] [CrossRef]
    • Trisomboon H, Malaivijitnond S, Watanabe G, Taya K. Estrogenic effects of Pueraria mirifica on the menstrual cycle and hormone-related ovarian functions in cyclic female cynomolgus monkeys. J Pharmacol Sci 2004; 94: 51-59. [Medline] [CrossRef]
    • (2004) J Pharmacol Sci , vol.94 , pp. 51-59
    • Trisomboon, H.1    Malaivijitnond, S.2    Watanabe, G.3    Taya, K.4
  • 20
    • 33646861393 scopus 로고    scopus 로고
    • The estrogenic effect of Pueraria mirifica on gonadotrophin levels in aged monkeys
    • [Medline] [CrossRef]
    • Trisomboon H, Malaivijitnond S, Watanabe G, Cherdshewasart W, Taya K. The estrogenic effect of Pueraria mirifica on gonadotrophin levels in aged monkeys. Endocrine 2006; 29: 129-134. [Medline] [CrossRef]
    • (2006) Endocrine , vol.29 , pp. 129-134
    • Trisomboon, H.1    Malaivijitnond, S.2    Watanabe, G.3    Cherdshewasart, W.4    Taya, K.5
  • 21
    • 21644474314 scopus 로고    scopus 로고
    • Naturally occurring menopause in cynomolgus monkeys: Changes in hormone, lipid, and carbohydrate measures with hormonal status
    • [Medline] [CrossRef]
    • Kavanagh K, Koudy Williams J, Wagner JD. Naturally occurring menopause in cynomolgus monkeys: changes in hormone, lipid, and carbohydrate measures with hormonal status. J Med Primatol 2005; 34: 171-177. [Medline] [CrossRef]
    • (2005) J Med Primatol , vol.34 , pp. 171-177
    • Kavanagh, K.1    Koudy Williams, J.2    Wagner, J.D.3
  • 22
    • 33747585809 scopus 로고    scopus 로고
    • Effects of high-dose soy isoflavones and equol on reproductive tissues in female cynomolgus monkeys
    • [Medline] [CrossRef]
    • Wood CE, Appt SE, Clarkson TB, Franke AA, Lees CJ, Doerge DR, Cline JM. Effects of high-dose soy isoflavones and equol on reproductive tissues in female cynomolgus monkeys. Biol Reprod 2006; 75: 477-486. [Medline] [CrossRef]
    • (2006) Biol Reprod , vol.75 , pp. 477-486
    • Wood, C.E.1    Appt, S.E.2    Clarkson, T.B.3    Franke, A.A.4    Lees, C.J.5    Doerge, D.R.6    Cline, J.M.7
  • 24
    • 12344313399 scopus 로고    scopus 로고
    • Female sexual behavior, but not sex skin swelling, reliably indicates the timing of the fertile phase in wild long-tailed macaques (Macaca fascicularis)
    • [Medline] [CrossRef]
    • Engelhardt A, Hodges JK, Niemitz C, Heistermann M. Female sexual behavior, but not sex skin swelling, reliably indicates the timing of the fertile phase in wild long-tailed macaques (Macaca fascicularis). Horm Behav 2005; 47: 195-204. [Medline] [CrossRef]
    • (2005) Horm Behav , vol.47 , pp. 195-204
    • Engelhardt, A.1    Hodges, J.K.2    Niemitz, C.3    Heistermann, M.4
  • 25
    • 33748667067 scopus 로고    scopus 로고
    • Effect of Pueraria mirifica on the sexual skin coloration of aged menopausal cynomolgus monkeys
    • [Medline] [CrossRef]
    • Trisomboon H, Malaivijitnond S, Cherdshewasart W, Watanabe G, Taya K. Effect of Pueraria mirifica on the sexual skin coloration of aged menopausal cynomolgus monkeys. J Reprod Dev 2006; 52: 537-542. [Medline] [CrossRef]
    • (2006) J Reprod Dev , vol.52 , pp. 537-542
    • Trisomboon, H.1    Malaivijitnond, S.2    Cherdshewasart, W.3    Watanabe, G.4    Taya, K.5
  • 26
    • 34547093394 scopus 로고    scopus 로고
    • Female long-tailed macaques with scrotum-like structure
    • [Medline] [CrossRef]
    • Malaivijitnond S, Hamada Y, Suryobroto B, Takenaka O. Female long-tailed macaques with scrotum-like structure. Am J Primatol 2007; 69: 721-735. [Medline] [CrossRef]
    • (2007) Am J Primatol , vol.69 , pp. 721-735
    • Malaivijitnond, S.1    Hamada, Y.2    Suryobroto, B.3    Takenaka, O.4
  • 27
    • 0031833110 scopus 로고    scopus 로고
    • Urogenital aging-a hidden problem
    • [Medline] [CrossRef]
    • Samsioe G. Urogenital aging-a hidden problem. Am J Obstet Gynecol 1998; 178: S245-S249. [Medline] [CrossRef]
    • (1998) Am J Obstet Gynecol , vol.178
    • Samsioe, G.1
  • 29
    • 0020463048 scopus 로고
    • Effect of folate deficiency on the reproductive organs of female rhesus monkeys: A cytomorphological and cytokinetic study
    • [Medline]
    • Mohanty D, Das KC. Effect of folate deficiency on the reproductive organs of female rhesus monkeys: a cytomorphological and cytokinetic study. J Nutr 1982; 112: 1565-1576. [Medline]
    • (1982) J Nutr , vol.112 , pp. 1565-1576
    • Mohanty, D.1    Das, K.C.2
  • 31
    • 54449094639 scopus 로고    scopus 로고
    • Morphological and body color variation in Thai Macaca fascicularis fascicularis north and south of the Isthmus of Kra
    • [CrossRef]
    • Hamada Y, Suryobroto B, Goto S, Malaivijitnond S. Morphological and body color variation in Thai Macaca fascicularis fascicularis north and south of the Isthmus of Kra. Int J Primatol 2008; 29: 1271-1294. [CrossRef]
    • (2008) Int J Primatol , vol.29 , pp. 1271-1294
    • Hamada, Y.1    Suryobroto, B.2    Goto, S.3    Malaivijitnond, S.4
  • 32
    • 28444433428 scopus 로고    scopus 로고
    • Randomized clinical trial comparing conjugated equine estrogens and isoflavones in postmenopausal women: A pilot study
    • [Medline] [CrossRef]
    • Kaari C, Haidar MA, Júnior JM, Nunes MG, Quadros LG, Kemp C, Stavale JN, Baracat EC. Randomized clinical trial comparing conjugated equine estrogens and isoflavones in postmenopausal women: a pilot study. Maturitas 2006; 53: 49-58. [Medline] [CrossRef]
    • (2006) Maturitas , vol.53 , pp. 49-58
    • Kaari, C.1    Haidar, M.A.2    Júnior, J.M.3    Nunes, M.G.4    Quadros, L.G.5    Kemp, C.6    Stavale, J.N.7    Baracat, E.C.8
  • 33
    • 47949112305 scopus 로고    scopus 로고
    • Effects of lasofoxifene on the uterus, vagina and breast in ovariectomized cynomolgus monkeys (Macacafascicularis)
    • 158.e1-158.e8
    • Cline JM, Botts S, Lees CJ, Brommage R. Effects of lasofoxifene on the uterus, vagina and breast in ovariectomized cynomolgus monkeys (Macacafascicularis). Am J Obstet Gynecol 2008; 199: 158. e1-158. e8.
    • (2008) Am J Obstet Gynecol , vol.199
    • Cline, J.M.1    Botts, S.2    Lees, C.J.3    Brommage, R.4
  • 34
    • 0022805095 scopus 로고
    • Relationships between ovarian morphology, vaginal cytology, serum progesterone, and urinary immunoreactive pregnanediol during the menstrual cycle of the cynomolgus monkey
    • [Medline] [CrossRef]
    • Mehta RR, Jenco JM, Gaynor LV, Chatterton RT Jr. Relationships between ovarian morphology, vaginal cytology, serum progesterone, and urinary immunoreactive pregnanediol during the menstrual cycle of the cynomolgus monkey. Biol Reprod 1986; 35: 981-986. [Medline] [CrossRef]
    • (1986) Biol Reprod , vol.35 , pp. 981-986
    • Mehta, R.R.1    Jenco, J.M.2    Gaynor, L.V.3    Chatterton Jr., R.T.4
  • 35
    • 0033152459 scopus 로고    scopus 로고
    • Estrogen receptor alpha and beta expression in the vaginal walls and uterosacral ligaments of premenopausal and postmenopausal women
    • [Medline] [CrossRef]
    • Chen GD, Oliver RH, Leung BS, Lin LY, Yeh J. Estrogen receptor alpha and beta expression in the vaginal walls and uterosacral ligaments of premenopausal and postmenopausal women. Fertil Steril 1999; 71: 1099-1102. [Medline] [CrossRef]
    • (1999) Fertil Steril , vol.71 , pp. 1099-1102
    • Chen, G.D.1    Oliver, R.H.2    Leung, B.S.3    Lin, L.Y.4    Yeh, J.5
  • 36
    • 0017365869 scopus 로고
    • Estrogen and progesterone receptors in the female genital tract of humans and monkeys
    • [Medline] [CrossRef]
    • Flickinger GL, Elsner C, Illingworth DV, Muechler EK, Mikhail G. Estrogen and progesterone receptors in the female genital tract of humans and monkeys. Ann N Y Acad Sci 1977; 286: 180-189. [Medline] [CrossRef]
    • (1977) Ann N Y Acad Sci , vol.286 , pp. 180-189
    • Flickinger, G.L.1    Elsner, C.2    Illingworth, D.V.3    Muechler, E.K.4    Mikhail, G.5
  • 37
    • 0014503538 scopus 로고
    • Estrogen-binding substances of target tissues
    • [Medline] [CrossRef]
    • Jensen EV, Suzuki T, Numata M, Smith S, DeSombre ER. Estrogen-binding substances of target tissues. Steroids 1969; 13: 417-427. [Medline] [CrossRef]
    • (1969) Steroids , vol.13 , pp. 417-427
    • Jensen, E.V.1    Suzuki, T.2    Numata, M.3    Smith, S.4    DeSombre, E.R.5
  • 38
    • 40949134312 scopus 로고    scopus 로고
    • Effects of chronic genistein treatment in mammary gland, uterus, and vagina
    • [Medline] [CrossRef]
    • Rimoldi G, Christoffel J, Seidlova-Wuttke D, Jarry H, Wuttke W. Effects of chronic genistein treatment in mammary gland, uterus, and vagina. Environ Health Perspect 2007; 115(Suppl 1): 62-68. [Medline] [CrossRef]
    • (2007) Environ Health Perspect , vol.115 , Issue.SUPPL. 1 , pp. 62-68
    • Rimoldi, G.1    Christoffel, J.2    Seidlova-Wuttke, D.3    Jarry, H.4    Wuttke, W.5
  • 39
    • 79956065890 scopus 로고    scopus 로고
    • The effect of vaginally administered genistein in comparison with hyaluronic acid on atrophic epithelium in postmenopause
    • [Medline] [CrossRef]
    • Le Donne M, Caruso C, Mancuso A, Costa G, Iemmo R, Pizzimenti G, Cavallari V. The effect of vaginally administered genistein in comparison with hyaluronic acid on atrophic epithelium in postmenopause. Arch Gynecol Obstet 2011; 283: 1319-1323. [Medline] [CrossRef]
    • (2011) Arch Gynecol Obstet , vol.283 , pp. 1319-1323
    • Le Donne, M.1    Caruso, C.2    Mancuso, A.3    Costa, G.4    Iemmo, R.5    Pizzimenti, G.6    Cavallari, V.7
  • 40
    • 68449084537 scopus 로고    scopus 로고
    • Efficacy and safety of low-dose regimens of conjugated estrogens cream administered vaginally
    • [Medline] [CrossRef]
    • Bachmann G, Bouchard C, Hoppe D, Ranganath R, Altomare C, Vieweg A, Graepel J, Helzner E. Efficacy and safety of low-dose regimens of conjugated estrogens cream administered vaginally. Menopause 2009; 16: 719-727. [Medline] [CrossRef]
    • (2009) Menopause , vol.16 , pp. 719-727
    • Bachmann, G.1    Bouchard, C.2    Hoppe, D.3    Ranganath, R.4    Altomare, C.5    Vieweg, A.6    Graepel, J.7    Helzner, E.8
  • 41
    • 0032879164 scopus 로고    scopus 로고
    • Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification
    • [Medline]
    • Boskey ER, Telsch KM, Whaley KJ, Moench TR, Cone RA. Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification. Infect Immun 1999; 67: 5170-5175. [Medline]
    • (1999) Infect Immun , vol.67 , pp. 5170-5175
    • Boskey, E.R.1    Telsch, K.M.2    Whaley, K.J.3    Moench, T.R.4    Cone, R.A.5
  • 43
    • 0142010625 scopus 로고    scopus 로고
    • Prevalence and determinants of vaginal flora alterations in postmenopausal women
    • [Medline] [CrossRef]
    • Pabich WL, Fihn SD, Stamm WE, Scholes D, Boyko EJ, Gupta K. Prevalence and determinants of vaginal flora alterations in postmenopausal women. J Infect Dis 2003; 188: 1054-1058. [Medline] [CrossRef]
    • (2003) J Infect Dis , vol.188 , pp. 1054-1058
    • Pabich, W.L.1    Fihn, S.D.2    Stamm, W.E.3    Scholes, D.4    Boyko, E.J.5    Gupta, K.6
  • 44
    • 30344473309 scopus 로고    scopus 로고
    • Vaginal microbial diversity among postmenopausal women with and without hormone replacement therapy
    • [Medline] [CrossRef]
    • Heinemann C, Reid G. Vaginal microbial diversity among postmenopausal women with and without hormone replacement therapy. Can J Microbiol 2005; 51: 777-781. [Medline] [CrossRef]
    • (2005) Can J Microbiol , vol.51 , pp. 777-781
    • Heinemann, C.1    Reid, G.2
  • 46
    • 64049083020 scopus 로고    scopus 로고
    • Effect of one-week treatment with vaginal estrogen preparations on serum estrogen levels in postmenopausal women
    • [Medline] [CrossRef]
    • Labrie F, Cusan L, Gomez JL, Côté I, Bérubé R, Bélanger P, Martel C, Labrie C. Effect of one-week treatment with vaginal estrogen preparations on serum estrogen levels in postmenopausal women. Menopause 2009; 16: 30-36. [Medline] [CrossRef]
    • (2009) Menopause , vol.16 , pp. 30-36
    • Labrie, F.1    Cusan, L.2    Gomez, J.L.3    Côté, I.4    Bérubé, R.5    Bélanger, P.6    Martel, C.7    Labrie, C.8
  • 47
    • 0026738205 scopus 로고
    • Low-dose oestradiol in the treatment of urogenital oestrogen deficiency-a pharmacokinetic and pharmacodynamic study
    • [Medline] [CrossRef]
    • Nilsson K, Heimer G. Low-dose oestradiol in the treatment of urogenital oestrogen deficiency-a pharmacokinetic and pharmacodynamic study. Maturitas 1992; 15: 121-127. [Medline] [CrossRef]
    • (1992) Maturitas , vol.15 , pp. 121-127
    • Nilsson, K.1    Heimer, G.2
  • 48
    • 0027986435 scopus 로고
    • Release of 17-beta-oestradiol from a vaginal ring in postmenopausal women: Pharmacokinetic evaluation
    • [Medline] [CrossRef]
    • Schmidt G, Andersson SB, Nordle O, Johansson CJ, Gunnarsson PO. Release of 17-beta-oestradiol from a vaginal ring in postmenopausal women: pharmacokinetic evaluation. Gynecol Obstet Invest 1994; 38: 253-260. [Medline] [CrossRef]
    • (1994) Gynecol Obstet Invest , vol.38 , pp. 253-260
    • Schmidt, G.1    Andersson, S.B.2    Nordle, O.3    Johansson, C.J.4    Gunnarsson, P.O.5
  • 49
    • 0017598803 scopus 로고
    • Relationship between sexual skin colour of female rhesus monkeys and midcycle plasma levels of oestradiol and progesterone
    • [Medline] [CrossRef]
    • Czaja JA, Robinson JA, Eisele SG, Scheffler G, Goy RW. Relationship between sexual skin colour of female rhesus monkeys and midcycle plasma levels of oestradiol and progesterone. J Reprod Fertil 1977; 49: 147-150. [Medline] [CrossRef]
    • (1977) J Reprod Fertil , vol.49 , pp. 147-150
    • Czaja, J.A.1    Robinson, J.A.2    Eisele, S.G.3    Scheffler, G.4    Goy, R.W.5
  • 50
    • 85027954857 scopus 로고    scopus 로고
    • Non-lactating versus lactating females: A comparison of sex steroids, sexual coloration, and sexual behavior in Japanese macaques
    • [Medline] [CrossRef]
    • Wallner B, Aspernig D, Millesi E, Machatschke IH. Non-lactating versus lactating females: a comparison of sex steroids, sexual coloration, and sexual behavior in Japanese macaques. Primates 2011; 52: 69-75. [Medline] [CrossRef]
    • (2011) Primates , vol.52 , pp. 69-75
    • Wallner, B.1    Aspernig, D.2    Millesi, E.3    McHatschke, I.H.4
  • 51
    • 0017587938 scopus 로고
    • Effects of estradiol benzoate, estrone, and propionates of testosterone or dihydrotestosterone on sexual and related behaviors of ovariectomized Rhesus monkeys
    • [Medline] [CrossRef]
    • Wallen K, Goy RW. Effects of estradiol benzoate, estrone, and propionates of testosterone or dihydrotestosterone on sexual and related behaviors of ovariectomized Rhesus monkeys. Horm Behav 1977; 9: 228-248. [Medline] [CrossRef]
    • (1977) Horm Behav , vol.9 , pp. 228-248
    • Wallen, K.1    Goy, R.W.2
  • 52
    • 0017058495 scopus 로고
    • Seasonal sex skin coloration and hormonal fluctuations in free-ranging and captive monkeys
    • [Medline] [CrossRef]
    • Baulu J. Seasonal sex skin coloration and hormonal fluctuations in free-ranging and captive monkeys. Horm Behav 1976; 7: 481-494. [Medline] [CrossRef]
    • (1976) Horm Behav , vol.7 , pp. 481-494
    • Baulu, J.1
  • 53
    • 0043128116 scopus 로고    scopus 로고
    • Clinical trial of the phytoestrogen rich herb, Pueraria mirifica as a crude drug in the treatment of symptoms in menopausal woman
    • Muangman V, Cherdshewasart W. Clinical trial of the phytoestrogen rich herb, Pueraria mirifica as a crude drug in the treatment of symptoms in menopausal woman. Siriraj Hosp Gaz 2001; 53: 300-309.
    • (2001) Siriraj Hosp Gaz , vol.53 , pp. 300-309
    • Muangman, V.1    Cherdshewasart, W.2
  • 54
    • 40249116220 scopus 로고    scopus 로고
    • Preventive effects of Pueraria mirifica on bone loss in ovariectomized rats
    • [Medline] [CrossRef]
    • Urasopon N, Hamada Y, Cherdshewasart W, Malaivijitnond S. Preventive effects of Pueraria mirifica on bone loss in ovariectomized rats. Maturitas 2008; 59: 137-148. [Medline] [CrossRef]
    • (2008) Maturitas , vol.59 , pp. 137-148
    • Urasopon, N.1    Hamada, Y.2    Cherdshewasart, W.3    Malaivijitnond, S.4
  • 55
    • 33748457158 scopus 로고    scopus 로고
    • Effects of Pueraria mirifica on vascular function of ovariectomized rabbits
    • [Medline]
    • Wattanapitayakul SK, Chularojmontri L, Srichirat S. Effects of Pueraria mirifica on vascular function of ovariectomized rabbits. J Med Assoc Thai 2005; 88(Suppl 1): S21-S29. [Medline]
    • (2005) J Med Assoc Thai , vol.88 , Issue.SUPPL. 1
    • Wattanapitayakul, S.K.1    Chularojmontri, L.2    Srichirat, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.