Design and synthesis of an artificial pulmonary pleura for high throughput studies in acellular human lungs

Cellular and Molecular Bioengineering

Volumn 7, Issue 2, 2014, Pages 184-195

  Wagner, Darcy E ^a   Fenn, Spencer L ^b   Bonenfant, Nicholas R ^a   Marks, Elliot R ^a   Borg, Zachary ^a   Saunders, Patrick ^a   Oldinski, Rachael A ^b   Weiss, Daniel J ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b University of Vermont   (United States)

Author keywords

Alginate; Artificial pleura; Decellularization; Lung; Ventilation

Indexed keywords

ALGINIC ACID; CALCIUM ALGINATE; CALCIUM CHLORIDE; EOSIN; METHACRYLIC ACID; TRIETHANOLAMINE;

ARTICLE; ARTIFICIAL PULMONARY PLEURA; CADAVER; CELL ADHESION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROGEL; MATERIAL COATING; MOLECULAR WEIGHT; PHOTOCROSSLINKING; PHYSICAL PARAMETERS; PLEURA; PLEURAL COATING; PRIORITY JOURNAL; TEMPERATURE; VISCOSITY;

ANIMALIA; RODENTIA;

EID: 84903783407     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-014-0323-1     Document Type: Article

References (40)

1. Bonenfant, N. R., D. Sokocevic, D. E. Wagner, et al. The effects of storage and sterilization on de-cellularized and re-cellularized whole lung. Biomaterials 34:3231-3245, 2013.
2. Bonvillain, R. W., S. Danchuk, D. E. Sullivan, et al. A nonhuman primate model of lung regeneration: detergent-mediated decellularization and initial in vitro recellularization with mesenchymal stem cells. Tissue Eng. Part A 18:2437-2452, 2012.
3. Booth, A. J., R. Hadley, A. M. Cornett, et al. Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation. Am. J. Respir. Crit. Care Med. 186:866-876, 2012.
4. Burdick, J. A., C. Chung, X. Jia, M. A. Randolph, and R. Langer. Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks. Biomacromolecules 6:386-391, 2004. (Pubitemid 40277037)
5. Cortiella, J., J. Niles, A. Cantu, et al. Influence of acellular natural lung matrix on murine embryonic stem cell differentiation and tissue formation. Tissue Eng. Part A 16:2565-2580, 2010.
6. Daly, A. B., J. M. Wallis, Z. D. Borg, et al. Initial binding and recellularization of decellularized mouse lung scaffolds with bone marrow-derived mesenchymal stromal cells. Tissue Eng. Part A 18:1-16, 2012.
7. Gilpin, S. E., J. P. Guyette, G. Gonzalez, et al. Perfusion decellularization of human and porcine lungs: bringing the matrix to clinical scale. J. Heart Lung Transpl. 2013. doi: 10.1016/j.healun.2013.10.030.
8. Gombotz, W. R., and S. F. Wee. Protein release from alginate matrices. Adv. Drug Deliv. Rev. 31:267-285, 1998. (Pubitemid 28191869)
9. Jay, S. M., and W. M. Saltzman. Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking. J. Controlled Release 134:26-34, 2009.
10. Jensen, T., B. Roszell, F. Zang, et al. A rapid lung decellularization protocol supports embryonic stem cell differentiation in vitro and following implantation. Tissue Eng. Part C 18:632-646, 2012.
11. Jeon, O., K. H. Bouhadir, J. M. Mansour, and E. Alsberg. Photocrosslinked alginate hydrogels with tunable biodegradation rates and mechanical properties. Biomaterials 30:2724-2734, 2009.
12. Kim, J., Y. Park, G. Tae, et al. Characterization of low-molecular-weight hyaluronic acid-based hydrogel and differential stem cell responses in the hydrogel microenvironments. J. Biomed. Mater. Res. A 88A:967-975, 2009.
13. Kuo, C. K., and P. X. Ma. Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: part 1. Structure, gelation rate and mechanical properties. Biomaterials 22:511-521, 2001. (Pubitemid 32015873)
14. Lee, K. Y., and D. J. Mooney. Alginate: properties and biomedical applications. Prog. Polym. Sci. 37:106-126, 2012.
15. Lemoine, D., F. Wauters, S. Bouchend'homme, and V. Préat. Preparation and characterization of alginate microspheres containing a model antigen. Int. J. Pharm. 176:9-19, 1998.
16. Liu, W. F., M. Ma, K. M. Bratlie, T. T. Dang, R. Langer, and D. G. Anderson. Real-time in vivo detection of bio-material-induced reactive oxygen species. Biomaterials 32:1796-1801, 2011.
17. Longmire, T. A., L. Ikonomou, F. Hawkins, et al. Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell 10:398-411, 2012.
18. Macchiarini, P., J. Wain, S. Almy, and P. Dartevelle. Experimental and clinical evaluation of a new synthetic, absorbable sealant to reduce air leaks in thoracic operations. J. Thorac. Cardiovasc. Surg. 117:751-758, 1999. (Pubitemid 29163080)
19. Muller, R., E. Gerard, P. Dugand, P. Rempp, and Y. Gnanou. Rheological characterization of the gel point: a new interpretation. Macromolecules 24:1321-1326, 1991.
20. Nichols, J. E., J. Niles, M. Riddle, et al. Production and assessment of decellularized pig and human lung scaffolds. Tissue Eng. Part A 19:2045-2062, 2013.
21. Ohta, S., M. Hirose, and H. Ishibashi. Pleural covering method of polyglycolic acid felt with sodium alginate water solution for prevention of postoperative pulmonary fistula. Kyobu Geka 61:561-563, 2008.
22. O'Neill, J. D., R. Anfang, A. Anandappa, et al. Decellularization of human and porcine lung tissues for pulmonary tissue engineering. Ann. Thorac. Surg. 96:1046-1056, 2013.
23. Ott, H. C., B. Clippinger, C. Conrad, et al. Regeneration and orthotopic transplantation of a bioartificial lung. Nat. Med. 16:927-933, 2010.
24. Park, Y. D., N. Tirelli, and J. A. Hubbell. Photopolymerized hyaluronic acid-based hydrogels and interpenetrating networks. Biomaterials 24:893-900, 2003. (Pubitemid 36024167)
25. Pawar, S. N., and K. J. Edgar. Alginate derivatization: a review of chemistry, properties and applications. Biomaterials 33:3279-3305, 2012.
26. Petersen, T. H., E. A. Calle, L. Zhao, et al. Tissue-engineered lungs for in vivo implantation. Science 329:538-541, 2010.
27. Price, A. P., K. A. England, A. M. Matson, B. R. Blazar, and A. Panoskaltsis-Mortari. Development of a decellularized lung bioreactor system for bioengineering the lung: the matrix reloaded. Tissue Eng. Part A 16:2581-2591, 2010.
28. Smeds, K. A., A. Pfister-Serres, D. Miki, et al. Photo-crosslinkable polysaccharides for in situ hydrogel formation. J. Biomed. Mater. Res. 55:254-255, 2001.
29. Smidsrød, O. Solution properties of alginate. Carbohydr. Res. 13:359-372, 1970.
30. Sokocevic, D., N. R. Bonenfant, D. E. Wagner, et al. The effect of age and emphysematous and fibrotic injury on the re-cellularization of de-cellularized lungs. Biomaterials 34:3256-3269, 2013.
31. Song, J. J., S. S. Kim, Z. Liu, et al. Enhanced in vivo function of bioartificial lungs in rats. Ann. Thorac. Surg. 92:998-1006, 2011.
32. Tonnesen, H. H., and J. Karlsen. Alginate in drug delivery systems. Drug Dev. Ind. Pharm. 28:621-630, 2002. (Pubitemid 34809561)
33. Wagner, D. E., N. R. Bonenfant, C. S. Parsons, et al. Comparative decellularization and recellularization of normal versus emphysematous human lungs. Biomaterials 35:3281-3297, 2014.
34. Wagner, D. E., N. R. Bonenfant, D. Sokocevic, et al. Three-dimensional scaffolds of acellular human and porcine lungs for high throughput studies of lung disease and regeneration. Biomaterials 35(9):2664-2679, 2014.
35. Wagner, D. E., R. W. Bonvillain, T. Jensen, et al. Can stem cells be used to generate new lungs? Ex vivo lung bioengineering with decellularized whole lung scaffolds. Respirology 18:895-911, 2013.
36. Wallis, J. M., Z. D. Borg, A. B. Daly, et al. Comparative assessment of detergent-based protocols for mouse lung decellularization and re-cellularization. Tissue Eng. Part C 18:420-432, 2012.
37. Winter, H. H. Can the gel point of a cross-linking polymer be detected by the G′-G″ crossover? Polym. Eng. Sci. 27:1698-1702, 1987.
38. Yang, D., and K. S. Jones. Effect of alginate on innate immune activation of macrophages. J. Biomed. Mater. Res. A 90A:411-418, 2009.
39. Yankaskas, J. R., J. E. Haizlip, M. Conrad, et al. Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype. Am. J. Physiol. 264:C1219-C1230, 1993. (Pubitemid 23158828)
40. Zar, J. Biostatistical Analysis. Upper Saddle River, NJ: Prentice-Hall, 2009.