Site-directed mutagenesis of the P225, N230 and H272 residues of succinate dehydrogenase subunit B from Botrytis cinerea highlights different roles in enzyme activity and inhibitor binding

Environmental Microbiology

Volumn 16, Issue 7, 2014, Pages 2253-2266

  Lalève, Anaïs ^a,c   Gamet, Stéphanie ^b   Walker, Anne Sophie ^a   Debieu, Danièle ^a   Toquin, Valérie ^b   Fillinger, Sabine ^a  

^a INRA Institut National de la Recherche Agronomique   (France)

^b BAYER AG   (Germany)

^c CENTRE DE GÉNÉTIQUE MOLÉCULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BOTRYOTINIA FUCKELIANA;

N-(2-(3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDYL)ETHYL)-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLUAMIDE; 2 CHLORO N (4 CHLOROBIPHENYL 2 YL)NICOTINAMIDE; 2-CHLORO-N-(4-CHLOROBIPHENYL-2-YL)NICOTINAMIDE; BENZAMIDE DERIVATIVE; BIPHENYL DERIVATIVE; CARBOXIN; DRUG DERIVATIVE; ENZYME INHIBITOR; FUNGAL PROTEIN; FUNGICIDE; N (2 (3 CHLORO 5 (TRIFLUOROMETHYL) 2 PYRIDYL)ETHYL) ALPHA,ALPHA,ALPHA TRIFLUORO O TOLUAMIDE; NICOTINAMIDE; PYRIDINE DERIVATIVE; SUCCINATE DEHYDROGENASE;

AMINO ACID SUBSTITUTION; ANTIFUNGAL RESISTANCE; ARTICLE; BOTRYTIS; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN BINDING; PROTEIN SUBUNIT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; BENZAMIDES; BIPHENYL COMPOUNDS; BOTRYTIS; CARBOXIN; DRUG RESISTANCE, FUNGAL; ENZYME INHIBITORS; FUNGAL PROTEINS; FUNGICIDES, INDUSTRIAL; MUTAGENESIS, SITE-DIRECTED; NIACINAMIDE; PROTEIN BINDING; PROTEIN SUBUNITS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINATE DEHYDROGENASE;

EID: 84903753881     PISSN: 14622912     EISSN: 14622920     Source Type: Journal    
DOI: 10.1111/1462-2920.12282     Document Type: Article

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