The up-regulation of endothelin-1 and down-regulation of miRNA-125a-5p, -155, and -199a/b-3p in human atherosclerotic coronary artery

Cardiovascular Pathology

Volumn 23, Issue 4, 2014, Pages 217-223

  Hao, Li ^a   Wang, Xiao Guang ^a   Cheng, Jian Ding ^a   You, Sheng Zhong ^a   Ma, Su Hua ^a   Zhong, Xia ^a   Quan, Li ^a,b   Luo, Bin ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II; Coronary atherosclerosis; Endothelin 1; MicroRNAs

Indexed keywords

ALPHA ACTIN; ANGIOTENSIN II; CD68 ANTIGEN; ENDOTHELIN 1; MICRORNA; MICRORNA 125A 5P; MICRORNA 155; MICRORNA 199A 3P; MICRORNA 199B 3P; UNCLASSIFIED DRUG; MIRN125 MICRORNA, HUMAN; MIRN155 MICRORNA, HUMAN; MIRN199 MICRORNA, HUMAN;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; ATHEROSCLEROTIC PLAQUE; CORONARY ARTERY; CORONARY ARTERY ATHEROSCLEROSIS; DOWN REGULATION; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MACROPHAGE; MALE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; CORONARY ARTERY DISEASE; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PERICARDIAL EFFUSION;

ACUTE CORONARY SYNDROME; ADULT; ANGIOTENSIN II; CORONARY ARTERY DISEASE; DOWN-REGULATION; ENDOTHELIN-1; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICRORNAS; MIDDLE AGED; PERICARDIAL EFFUSION; PLAQUE, ATHEROSCLEROTIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 84903733607     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2014.03.009     Document Type: Article

References (36)

1. R Virmani, FD Kolodgie, AP Burke, AV Finn, HK Gold, and TN Tulenko et al. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage Arterioscler Thromb Vasc Biol 25 2005 2054 2061
2. WE Hellings, W Peeters, FL Moll, and G Pasterkamp From vulnerable plaque to vulnerable patient: the search for biomarkers of plaque destabilization Trends Cardiovasc Med 17 2007 162 171
3. FD Russell, and AP Davenport Secretory pathways in endothelin synthesis Br J Pharmacol 126 1999 391 398
4. RM Kedzierski, and M Yanagisawa Endothelin system: the double-edged sword in health and disease Annu Rev Pharmacol Toxicol 41 2001 851 876
5. Y Fujitani, H Ninomiya, T Okada, Y Urade, and T Masaki Suppression of endothelin-1-induced mitogenic responses of human aortic smooth muscle cells by interleukin-1 beta J Clin Invest 95 1995 2474 2482
6. H Ruetten, and C Thiemermann Endothelin-1 stimulates the biosynthesis of tumour necrosis factor in macrophages: ET-receptors, signal transduction and inhibition by dexamethasone J Physiol Pharmacol 48 1997 675 688
7. SH Wilson, RD Simari, and A Lerman The effect of endothelin-1 on nuclear factor kappa B in macrophages Biochem Biophys Res Commun 286 2001 968 972
8. MR Dashwood, and JC Tsui Endothelin-1 and atherosclerosis: potential complications associated with endothelin-receptor blockade Atherosclerosis 160 2002 297 304
9. J Xiao, and YH Chen MicroRNAs: novel regulators of the heart J Thorac Dis 2 2010 43 47
10. S Dimmeler, and AM Zeiher Circulating microRNAs: novel biomarkers for cardiovascular diseases? Eur Heart J 31 2010 2705 2707
11. K Bidzhekov, L Gan, B Denecke, A Rostalsky, M Hristov, and TA Koeppel et al. microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans Thromb Haemost 107 2012 619 625
12. F Cipollone, L Felicioni, R Sarzani, S Ucchino, F Spigonardo, and C Mandolini et al. A unique microRNA signature associated with plaque instability in humans Stroke 42 2011 2556 2563
13. E Raitoharju, LP Lyytikainen, M Levula, N Oksala, A Mennander, and M Tarkka et al. miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study Atherosclerosis 219 2011 211 217
14. S Fichtlscherer, S De Rosa, H Fox, T Schwietz, A Fischer, and C Liebetrau et al. Circulating microRNAs in patients with coronary artery disease Circ Res 107 2010 677 684
15. S Hoshida, J Kato, M Nishino, Y Egami, T Takeda, and M Kawabata et al. Increased angiotensin-converting enzyme activity in coronary artery specimens from patients with acute coronary syndrome Circulation 103 2001 630 633
16. M Ihara, H Urata, A Kinoshita, J Suzumiya, M Sasaguri, and M Kikuchi et al. Increased chymase-dependent angiotensin II formation in human atherosclerotic aorta Hypertension 33 1999 1399 1405
17. A Lerman, BS Edwards, JW Hallett, DM Heublein, SM Sandberg, and JJ Burnett Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis N Engl J Med 325 1991 997 1001
18. MR Dashwood, SG Barker, JR Muddle, MH Yacoub, and JF Martin [125I]-endothelin-1 binding to vasa vasorum and regions of neovascularization in human and porcine blood vessels: a possible role for endothelin in intimal hyperplasia and atherosclerosis J Cardiovasc Pharmacol 22 Suppl. 8 1993 S343 S347
19. SB Chai, XM Li, YZ Pang, YF Qi, and CS Tang Increased plasma levels of endothelin-1 and urotensin-II in patients with coronary heart disease Heart Vessels 25 2010 138 143
20. A Saeed, H Herlitz, E Nowakowska-Fortuna, U Nilsson, A Alhadad, and G Jensen et al. Oxidative stress and endothelin-1 in atherosclerotic renal artery stenosis and effects of renal angioplasty Kidney Blood Press Res 34 2011 396 403
21. H Liu, Y Peng, F Liu, Y Liu, L Ouyang, and W Xiao et al. Correlation between endothelin-1 and atherosclerosis in chronic hemodialysis patients J Nephrol 23 2010 593 602
22. HB Yang, XY Zhao, JY Zhang, YY Du, and XF Wang Pioglitazone induces regression and stabilization of coronary atherosclerotic plaques in patients with impaired glucose tolerance Diabet Med 29 2012 359 365
23. A Namiki, T Kubota, M Fukazawa, M Ishikawa, M Moroi, and J Aikawa et al. Endothelin-1 concentrations in pericardial fluid are more elevated in patients with ischemic heart disease than in patients with nonischemic heart disease Jpn Heart J 44 2003 633 644
24. GP Rossi, S Colonna, E Pavan, G Albertin, RF Della, G Gerosa, D Casarotto, S Sartore, P Pauletto, and AC Pessina Endothelin-1 and its mRNA in the wall layers of human arteries ex vivo Circulation 99 1999 1147 1155
25. JA Winkles, GF Alberts, E Brogi, and P Libby Endothelin-1 and endothelin receptor mRNA expression in normal and atherosclerotic human arteries Biochem Biophys Res Commun 191 1993 1081 1088
26. GT Jones, AM van Rij, C Solomon, IA Thomson, and SG Packer Endothelin-1 is increased overlying atherosclerotic plaques in human arteries Atherosclerosis 124 1996 25 35
27. D Li, P Yang, Q Xiong, X Song, X Yang, and L Liu et al. MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells J Hypertens 28 2010 1646 1654
28. S Yeligar, H Tsukamoto, and VK Kalra Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothelial cells involves hypoxia-inducible factor-1alpha and microrNA-199 J Immunol 183 2009 5232 5243
29. T Chen, Z Huang, L Wang, Y Wang, F Wu, and S Meng et al. MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages Cardiovasc Res 83 2009 131 139
30. C Goettsch, M Rauner, N Pacyna, U Hempel, SR Bornstein, and LC Hofbauer miR-125b regulates calcification of vascular smooth muscle cells Am J Pathol 179 2011 1594 1600
31. M Nazari-Jahantigh, Y Wei, H Noels, S Akhtar, Z Zhou, and RR Koenen et al. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages J Clin Invest 122 2012 4190 4202
32. RS Huang, GQ Hu, B Lin, ZY Lin, and CC Sun MicroRNA-155 silencing enhances inflammatory response and lipid uptake in oxidized low-density lipoprotein-stimulated human THP-1 macrophages J Investig Med 58 2010 961 967
33. T Chen, H Yan, Z Li, T Jing, W Zhu, and J Ge et al. MicroRNA-155 regulates lipid uptake, adhesion/chemokine marker secretion and SCG2 expression in oxLDL-stimulated dendritic cells/macrophages Int J Cardiol 147 2011 446 447
34. MM Donners, IM Wolfs, LJ Stoger, EP van der Vorst, CC Pottgens, and S Heymans et al. Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice PLoS One 7 2012 e35877
35. F Horkay, I Szokodi, L Selmeci, B Merkely, V Kekesi, and T Vecsey et al. Presence of immunoreactive endothelin-1 and atrial natriuretic peptide in human pericardial fluid Life Sci 62 1998 267 274
36. T Li, H Cao, J Zhuang, J Wan, M Guan, and B Yu et al. Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans Clin Chim Acta 412 2011 66 70