The genotoxin colibactin exacerbates lymphopenia and decreases survival rate in mice infected with septicemic Escherichia coli

Journal of Infectious Diseases

Volumn 210, Issue 2, 2014, Pages 285-294

  Marcq, Ingrid ^a,b,c,d,g   Martin, Patricia ^a,b,c,d   Payros, Delphine ^a,b,c,d   Cuevas Ramos, Gabriel ^a,b,c,d   Boury, Michèle ^a,b,c,d   Watrin, Claude ^a,b,c,d   Nougayrède, Jean Philippe ^a,b,c,d   Olier, Maïwenn ^a,b,c,d,e   Oswald, Eric ^a,b,c,d,f  

^a INSERM   (France)

^b INRA   (France)

^c CNRS   (France)

^d France   (France)

^e TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

^f CHU PURPAN   (France)

^g UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

Author keywords

colibactin

Indexed keywords

BACTERIAL TOXIN; COLIBACTIN; GENOTOXIN; GENTAMICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; APOPTOSIS; ARTICLE; BACTEREMIA; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CELL CYCLE ARREST; CONTROLLED STUDY; DISEASE EXACERBATION; DOUBLE STRANDED DNA BREAK; EXTRAINTESTINAL PATHOGENIC ESCHERICHIA COLI; FEMALE; GENOMIC ISLAND; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOCYTOPENIA; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; REHYDRATION; SEPSIS; SEPTICEMIA; SURVIVAL RATE; TOXIN SYNTHESIS;

COLIBACTIN; E. COLI; LYMPHONIA; SEPSIS; TOXIN;

ANIMALS; CELL DEATH; DNA BREAKS, DOUBLE-STRANDED; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; GENE DELETION; LYMPHOCYTES; LYMPHOPENIA; MICE; MICE, INBRED C57BL; MUTAGENS; PEPTIDES; POLYKETIDES; SEPSIS; SURVIVAL ANALYSIS; VIRULENCE; VIRULENCE FACTORS;

EID: 84903732455     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu071     Document Type: Article

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