PET/CT studies of multiple myeloma using 18F-FDG and 18F-NaF: Comparison of distribution patterns and tracers' pharmacokinetics

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 41, Issue 7, 2014, Pages 1343-1353

  Sachpekidis, Christos ^a   Goldschmidt, Hartmut ^a,b   Hose, Dirk ^a,b   Pan, Leyun ^a   Cheng, Caixia ^a   Kopka, Klaus ^a   Haberkorn, Uwe ^a,b   Dimitrakopoulou Strauss, Antonia ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Compartment analysis; Multiple myeloma; PET CT

Indexed keywords

FLUORODEOXYGLUCOSE F 18; SODIUM FLUORIDE F 18; TRACER; SODIUM FLUORIDE;

ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG UPTAKE; FEMALE; HUMAN; KINETICS; MAJOR CLINICAL STUDY; MALE; MULTIPLE MYELOMA; PROSPECTIVE STUDY; RADIATION DOSE; WHOLE BODY CT; WHOLE BODY PET; AGED; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC USE; METABOLISM; MIDDLE AGED; MULTIMODAL IMAGING; PELVIS; POSITRON EMISSION TOMOGRAPHY; RADIOGRAPHY; SCINTISCANNING; WHOLE BODY IMAGING;

AGED; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; MALE; MIDDLE AGED; MULTIMODAL IMAGING; MULTIPLE MYELOMA; PELVIS; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; SODIUM FLUORIDE; TOMOGRAPHY, X-RAY COMPUTED; WHOLE BODY IMAGING;

EID: 84903724209     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-014-2721-y     Document Type: Article

References (30)

1. International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol. 2003;121:749-57.
2. Palumbo A, Anderson K. Multiple myeloma. N Engl J Med. 2011;364:1046-60.
3. Walker RC, Brown TL, Jones-Jackson LB, De Blanche L, Bartel T. Imaging of multiple myeloma and related plasma cell dyscrasias. J Nucl Med. 2012;53:1091-101.
4. Mason NS, Lin EC. Basics of fluorodeoxyglucose radiochemistry and biology. In: Lin EC, Alavi A (eds). PET and PET/CT: a clinical guide. Thieme medical publisher, Inc 2005; p.15-20.
5. Durie BG, Waxman AD, D'Agnolo A, Williams CM. Whole-body (18)F-FDG PET identifies high-risk myeloma. J Nucl Med. 2002;43:1457-63. (Pubitemid 35285870)
6. Schirrmeister H, Bommer M, Buck AK, Müller S, Messer P, Bunjes D, et al. Initial results in the assessment of multiple myeloma using 18 F-FDG PET. Eur J Nucl Med Mol Imaging. 2002;29:361-6. (Pubitemid 34253248)
7. Bredella MA, Steinbach L, Caputo G, Segall G, Hawkins R. Value of FDG PET in the assessment of patients with multiple myeloma. AJR Am J Roentgenol. 2005;184:1199-204. (Pubitemid 43821897)
8. Fonti R, Larobina M, Del Vecchio S, De Luca S, Fabbricini R, Catalano L, et al. Metabolic tumor volume assessed by 18 F-FDG PET/CT for the prediction of outcome in patients with multiple myeloma. J Nucl Med. 2012;53:1829-35.
9. Durie BG. The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system. Eur J Cancer. 2006;42:1539-43. (Pubitemid 44137426)
10. Blau M, Ganatra R, Bender MA. 18 F-Fluoride for bone imaging. Semin Nucl Med. 1972;2:31-7.
11. Grant FD, Fahey FH, Packard AB, Davis RT, Alavi A, Treves ST. Skeletal PET with 18 F-fluoride: applying new technology to an old tracer. J Nucl Med. 2008;49:68-78.
12. Segall G, Delbeke D, Stabin MG, Even-Sapir E, Fair J, Sajdak R, et al. SNM. SNM practice guideline for sodium 18 F-fluoride PET/CT bone scans 1.0. J Nucl Med. 2010;51:1813-20.
13. Schiepers C, Nuyts J, Bormans G, Dequeker J, Bouillon R, Mortelmans L, et al. Fluoride kinetics of the axial skeleton measured in vivo with fluorine-18-fluoride PET. J Nucl Med. 1997;38:1970-6. (Pubitemid 28030932)
14. Hawkins RA, Choi Y, Huang SC, Hoh CK, Dahlbom M, Schiepers C, et al. Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET. J Nucl Med. 1992;33:633-42.
15. Nishiyama Y, Tateishi U, Shizukuishi K, Shishikura A, Yamazaki E, Shibata H, et al. Role of 18 F-fluoride PET/CT in the assessment of multiple myeloma: initial experience. Ann Nucl Med. 2013;27:78-83.
16. Sokoloff L, Smith CB. Basic principles underlying radioisotopic methods for assay of biochemical processes in vivo. In: Greitz T, Ingvar DH, Widén L, editors. The metabolism of the human brain studied with positron emission tomography. New York: Raven Press; 1983. p. 123-48.
17. Dimitrakopoulou-Strauss A, Strauss LG, Burger C, Mikolajczyk K, Lehnert T, Bernd L, et al. On the fractal nature of positron emission tomography (PET) studies. World J Nucl Med. 2003;4:306-13.
18. Dimitrakopoulou-Strauss A, Pan L, Strauss LG. Quantitative approaches of dynamic FDG-PET and PET/CT studies (dPET/CT) for the evaluation of oncological patients. Cancer Imaging. 2012;12:283-9.
19. Pan L, Mikolajczyk K, Strauss L, Haberkorn U, Dimitrakopoulou-Srrauss A. Machine learning based parameter imaging and kinetic modeling of PET data. J Nucl Med. 2007;48:158p.
20. Strauss LG, Conti PS. The applications of PET in clinical oncology. J Nucl Med. 1991;32:623-48.
21. Burger C, Buck A. Requirements and implementations of a flexible kinetic modeling tool. J Nucl Med. 1997;38:1818-23. (Pubitemid 27495539)
22. Mikolajczyk K, Szabatin M, Rudnicki P, Grodzki M, Burger C. A Java environment for medical image data analysis: initial application for brain PET quantitation. Med Inform. 1998;23:207-14. (Pubitemid 28451333)
23. Miyazawa H, Osmont A, Petit-Taboué MC, Tillet I, Travère JM, Young AR, et al. Determination of 18 F-fluoro-2-deoxy-D-glucose rate constants in the anesthetized baboon brain with dynamic positron tomography. J Neurosci Methods. 1993;50:263-72.
24. 18F-fluoride. Mol Imaging Biol. 2013;15:336-44.
25. Ohtake T, Kosaka N, Watanabe T, Yokoyama I, Moritan T, Masuo M, et al. Noninvasive method to obtain input function for measuring tissue glucose utilization of thoracic and abdominal organs. J Nucl Med. 1991;32:1432-8.
26. Strauss LG, Klippel S, Pan L, Schönleben K, Haberkorn U, Dimitrakopoulou-Strauss A. Assessment of quantitative FDG PET data in primary colorectal tumours: which parameters are important with respect to tumour detection? Eur J Nucl Med Mol Imaging. 2007;34:868-77. (Pubitemid 46798955)
27. Bird JM, Owen RG, D'Sa S, Snowden JA, Pratt G, Ashcroft J, et al. Guidelines for the diagnosis and management of multiple myeloma 2011. Br J Haematol. 2011;154:32-75.
28. 18F-fluoro-deoxyglucose positron emission tomography in assessment of myeloma-related bone disease: a systematic review. Cancer. 2012;15(118):1971-81.
29. Czernin J, Satyamurthy N, Schiepers C. Molecular mechanisms of bone 18 F-NaF deposition. J Nucl Med. 2010;51:1826-9.
30. Dimitrakopoulou-Strauss A, Strauss LG, Heichel T, Wu H. Burger et al. The role of quantitative (18)F-FDG PET studies for the differentiation of malignant and benign bone lesions. J Nucl Med. 2002;43:510-8. (Pubitemid 34286347)