Improved chemosensitivity in cervical cancer to cisplatin: Synergistic activity of mahanine through STAT3 inhibition

Cancer Letters

Volumn 351, Issue 1, 2014, Pages 81-90

  Das, Ranjita ^a   Bhattacharya, Kaushik ^a   Samanta, Suman K ^a   Pal, Bikas C ^b   Mandal, Chitra ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

Author keywords

Cervical cancer; Cisplatin; Mahanine; STAT3; Synergism

Indexed keywords

ALKALOID; CASPASE; CISPLATIN; JANUS KINASE 1; MAHANINE; PROTEASOME; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL MIGRATION; CELL MOTILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UTERINE CERVIX CANCER;

CERVICAL CANCER; CISPLATIN; MAHANINE; STAT3; SYNERGISM;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARBAZOLES; CELL MOVEMENT; CELL SURVIVAL; CISPLATIN; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; FEMALE; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MEMBRANE POTENTIAL, MITOCHONDRIAL; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; STAT3 TRANSCRIPTION FACTOR; UTERINE CERVICAL NEOPLASMS;

EID: 84903710198     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.05.005     Document Type: Article

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