Long-term RNA persistence of Porcine rubulavirus (PorPV-LPMV) after an outbreak of a natural infection: The detection of viral mRNA in sentinel pigs suggests viral transmission

Virus Research

Volumn 188, Issue , 2014, Pages 155-161

  Cuevas Romero, S ^a,b   Hernandez Baumgarten E ^c   Kennedy, S ^d   Hernandez Jauregui P ^e   Berg, M ^a   Moreno Lopez J ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b INSTITUTO NACIONAL DE INVESTIGACIONES FORESTALES   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d AGRI FOOD AND BIOSCIENCES INSTITUTE   (United Kingdom)

^e INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Chronic natural infection; Long term persistence; Porcine rubulavirus; Viral transmission

Indexed keywords

ANTIBODY; MESSENGER RNA; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS PROTEIN; VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CERVICAL SPINAL CORD; CHOROID PLEXUS; CONTROLLED STUDY; CONVALESCENCE; CORPUS CALLOSUM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMORAL IMMUNITY; LUNG; MEDULLA OBLONGATA; MESENCEPHALON; NONHUMAN; OLFACTORY BULB; OPTIC NERVE; PANCREAS; PARAMYXOVIRUS; PARAMYXOVIRUS INFECTION; PORCINE RUBULAVIRUS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS; SALIVARY GLAND; SWINE; TONSIL; TRIGEMINAL NERVE; VIRUS INFECTIVITY; VIRUS TRANSMISSION; ANIMAL; ANIMAL STRUCTURES; BLOOD; EPIDEMIC; GENETICS; ISOLATION AND PURIFICATION; POLYMERASE CHAIN REACTION; RUBULAVIRUS; RUBULAVIRUS INFECTIONS; SERODIAGNOSIS; SWINE DISEASES; TIME; VETERINARY; VIROLOGY;

ANIMAL STRUCTURES; ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; DISEASE OUTBREAKS; ENZYME-LINKED IMMUNOSORBENT ASSAY; NEUTRALIZATION TESTS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, VIRAL; RUBULAVIRUS; RUBULAVIRUS INFECTIONS; SWINE; SWINE DISEASES; TIME FACTORS; VIRAL PROTEINS;

EID: 84903708674     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2014.04.012     Document Type: Article

References (34)

1. Ahmed R., Morrison L.A., Knipe D.M. Persistence of viruses. Fields Virology 1996, 219-249. Lippincott-Raven Publishers, Philadelphia. 3rd ed. B.M. Fields, D.M. Knipe, P.M. Howley (Eds.).
2. Allan G.M., McNeilly F., Walker I., Linné T., Moreno-López J., Hernández P., Kennedy S., Carroll B.P., Herron B., Foster J.C., Adair B. A sequential study of experimental porcine paramyxovirus (LPMV) infection of pigs: immunostaining of cryostat sections and virus isolation. J. Vet. Diagn. Invest. 1996, 8:405-413.
3. Berg M., Hjertner B., Moreno-Lopez J., Linne T. The P gene of the porcine paramyxovirus LPMV encodes three possible polypeptides P, V and C: the P protein mRNA is edited. J. Gen. Virol. 1992, 73:1195-1200.
4. Cuevas J.S., Rodríguez-Ropón A., Kennedy S., Moreno-López J., Berg M., Hernández-Jáuregui P. Investigation of T-cell responses and viral mRNA persistence in lymph nodes of pigs infected with Porcine rubulavirus. Vet. Immunol. Immunopathol. 2009, 127:148-152.
5. Cuevas-Romero S., Blomström A., Alvarado I.A., Hernández-Jáuregui P., Rivera-Benitez J.F., Ramírez-Mendoza H., Berg M. Development of a real-time RT-PCR method for detection of porcine rubulavirus (PoRV-LPMV). J. Virol. Methods 2013, 189:1-6.
6. Duvigneau J.C., Hartl R.T., Groiss S., Gemeiner M. Quantitative simultaneous multiplex real-time PCR for the detection of porcine cytokines. J. Immunol. Methods 2005, 306:16-27.
7. Escobar-López A.C., Rivera-Benitez J.F., Castillo-Juárez H., Ramírez-Mendoza H., Trujillo-Ortega M.E., Sánchez-Betancourt J.I. Identification of antigenic variants of the porcine rubulavirus in sera of field swine and their sero prevalence. Transbound. Emerg. Dis. 2012, 59:416-420.
8. Fearns R., Young D.F., Randall R.E. Evidence that the paramyxovirus simian virus 5 can establish quiescent infections by remaining inactive in cytoplasmic inclusion bodies. J. Gen. Virol. 1994, 75:3525-3539.
9. Fleige S., Pfaffl M.W. RNA integrity and the effect on the real-time qRT-PCR performance. Mol. Aspects Med. 2006, 27:126-139.
10. Garcin D., Melo De M., Roux L., Kolakofsky D., Curran J. Presence of a truncated form of the Sendai virus P protein in a long-term persistent infection: implications for the maintenance of the persistent state. Virology 1994, 15:19-25.
11. Guido Re G. Deletion mutants of paramyxoviruses. The Paramyxoviruses 1991, 275-298. Plenum Press, New York. D.W. Kingsbury (Ed.).
12. Haines D.M., Chelack B.J. Technical considerations for developing enzyme immunohistochemical staining procedures on formalin-fixed paraffin embedded tissues for diagnostic pathology. J. Vet. Diagn. Invest. 1991, 3:101-112.
13. Hernández-Jáuregui P., Yacoub A., Kennedy S., Curran B., Téllez C., Svenda M., Ljung L., Moreno-López J. Uptake of porcine rubulavirus (LPMV) by PK-15 cells. Arch. Med. Res. 2001, 32:400-409.
14. Hernández-Jáuregui P., Ramírez Mendoza H., Mercado García C., Moreno-López J., Kennedy S. Experimental Porcine rubulavirus (La Piedad-Michoacan virus) infection in pregnant gilts. J. Comp. Pathol. 2004, 130:1-6.
15. Hjertner B., Linné T., Moreno-López J. Establishment and characterisation of a porcine rubulavirus (LPMV) persistent infection in porcine kidney cells. Acta Vet. Scand. 1997, 38:213-224.
16. Hjertner B., Wiman A.C., Svenda M., Berg M., Moreno-López J., Linné T. Multiple factors including subgenomic RNAs and reduced viral protein expression are associated with a persistent infection by porcine rubulavirus (LPMV). Arch. Virol. 1998, 143:425-439.
17. Hoffmann B., Beer M., Schelp C., Schirrmeier H., Depner K. Validation of a realtime RT-PCR assay for sensitive and specific detection of classical swine fever. J. Virol. Methods 2005, 130:36-44.
18. Joly E., Mucke L., Oldstone M.B. Viral persistence in neurons explained by lack of major histocompatibility class I expression. Science 1991, 253:1283-1285.
19. Kirkland P., Stephano A. Paramyxoviruses: Rubulavirus, Menangle, and Nipah Virus Infections. Diseases of Swine 2006, 455-467. Blackwell Publishing, Ames, IA. 9th ed.
20. McNeilly F., Walker I., Allan G.M., Foster J.C., Linne T., Merza M., Hernandez P., Kennedy S., Adair B. A comparative study on the use of virus and antibody detection techniques for the diagnosis of La Piedad Michoacan paramyxovirus (LPMV) infection in pigs. J. Vet. Diagn. Invest. 1997, 9:3-9.
21. Moreno-López J., Correa-Girón P., Martínez A., Ericsson A. Characterization of a paramyxovirus isolated from the brain of a piglet in Mexico. Arch. Virol. 1986, 91:221-231.
22. Mori I., Komatsu T., Takeuchi K., Nakakuki K., Sudo M., Kimura Y. Parainfluenza virus type 1 infects olfactory neurons and establishes long-term persistence in the nerve tissue. J. Gen. Virol. 1995, 76:1251-1254.
23. Morgulis A., Coulouris G., Raytselis Y., Madden T.L., Agarwala R., Schaffer A.A. Database indexing for production Mega BLAST searches. Bioinformatics 2008, 24:1757-1764.
24. Nagai Y., Yoshida T. Viral pathogenesis: mechanism of acute and persistent infections with paramyxoviruses. J. Med. Sci. 1984, 46:1-17.
25. Nordengrahn A., Svenda M., Moreno-López J., Bergvall A., Hernández P., McNeilly F., Allan G., Merza M. Development of a blocking ELISA for screening antibodies to porcine rubulavirus, La Piedad Michoacán Virus. J. Vet. Diagn. Invest. 1999, 11:319-323.
26. Ramírez-Mendoza H., Hernández-Jáuregui P., Reyes-Leyva J., Zenteno E., Moreno-López J., Kennedy S. Lesions in the reproductive tract of boars experimentally infected with porcine rubulavirus. J. Comp. Pathol. 1997, 117:237-252.
27. Randall R.E., Russell W.C. Paramyxovirus persistence: consequences for host and virus. The Paramyxoviruses 1991, 299-321. Plenum Press, New York. D.W. Kingsbury (Ed.).
28. Rivera-Benítez J.F., Martínez-Bautista R., Pérez-Torres A., García-Contreras A.C., Reyes-Leyva J., Hernández J., Ramírez-Mendoza H. Persistence of Porcine rubulavirus in experimentally infected boars. Vet. Microbiol. 2013, 162:491-498.
29. Rivera-Benítez J.F., Cuevas-Romero S., Pérez-Torres A., Reyes-Leyva J., Hernández J., Ramírez-Mendoza H. Respiratory disease in growing pigs after Porcine rubulavirus experimental infection. Virus Res. 2013, 176:137-143.
30. Sánchez-Betancourt J.I., Santos-López G., Alonso R., Doporti J.M., Ramírez-Mendoza H., Mendoza S., Hernández J., Reyes-Leyva J., Trujillo M.E. Molecular characterization of the hemagglutinin-neuraminidase gene of porcine rubulavirus isolates associated with neurological disorders in fattening and adult pigs. Res. Vet. Sci. 2008, 85:356-367.
31. Schneider-Schaulies J., Niewiesk S., Schneider-Schaulies S., ter Meulen V. Measles virus in the CNS: the role of viral and host factors for the establishment and maintenance a persistent infection. J. Neurovirol. 1999, 5:613-622.
32. Stephano H.A. Blue eye disease: clinical signs and lesions. Trends in Emerging Viral Infections of Swine 2002, 47-50. University Press, Iowa State, USA. A. Morilla, K. Yoon, J. Zimmerman (Eds.).
33. Wang L.F., Collins P.L., Fouchier R.A.M., Kurath G., Lamb R.A., Randall R.E., Rima B.K. Paramyxoviridae. Virus Taxonomy: Classification and Nomenclature of Viruses. Ninth Report of the International Committee on Taxonomy of Viruses 2012, 640-653. Elsevier Academic Press, San Diego, CA. A.M.Q. King, M.J. Adams, E.B. Carstens, E.J. Lefkowitz (Eds.).
34. Wiman A.C., Hjertner B., Linné T., Herron B., Allan G., McNeilly F., Adair B., Moreno-López J., Berg M. Porcine rubulavirus LPMV RNA persists in the central nervous system of pigs after recovery from acute infection. J. Neurovirol. 1998, 4:545-552.