Measles virus in the CNS: The role of viral and host factors for the establishment and maintenance of a persistent infection

Journal of NeuroVirology

Volumn 5, Issue 6, 1999, Pages 613-622

  Schneider Schaulies, Jürgen ^a   Niewiesk, Stefan ^a   Schneider Schaulies, Sibylle ^a   Ter Meulen, Volker ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

CD46 transgenic animals; Measles virus; Persistent infection; Recombinant measles viruses; Subacute sclerosing panencephalitis (SSPE)

Indexed keywords

CYTOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN;

CELLULAR IMMUNITY; CENTRAL NERVOUS SYSTEM INFECTION; HUMAN; HUMORAL IMMUNITY; MEASLES; MEASLES VIRUS; NEUROTROPISM; NONHUMAN; PANENCEPHALITIS; PERSISTENT INFECTION; PRIORITY JOURNAL; REVIEW; VIRUS GENOME; VIRUS IMMUNITY;

EID: 0033386148     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289909021290     Document Type: Review

References (102)

1. Allen IV, McQuaid S, McMahon J, Kirk J, McConnel R (1996). The significance of measles virus antigen and genome distribution in the CNS in SSPE for mechanisms of viral spread and demyelination. J Neuropath Exp Neurol 55: 471-480.
2. Baczko K, Lampe J, Liebert UG, Brinckmann U, ter Meulen V, Pardowitz J, Budka H, Cosby SL, Isserte S, Rima BK (1993). Clonal expansion of hypermutated measles virus in a SSPE brain. Virology 197: 188 - 195.
3. Baczko K, Liebert UG, Billeter MA, Cattaneo R, Budka H, ter Meulen V (1986). Expression of defective measles virus genes in brain tissue of patients with subacute sclerosing panencephalitis. J Virol 59: 472 - 478.
4. Bankamp B, Brinckmann U, Reich A, Niewiesk S, ter Meulen V, Liebert UG (1991). Measles virus nucleocapsid protein protects rats from encephalitis. J Virol 65: 1695 - 1700.
5. Barrett PN, Koschel K, Carter M, ter Meulen V (1985). Effect of measles virus antibodies on a measles SSPE virus persistently infected C6 rat-glioma cell line. J Gen Virol 66: 1411 - 1421.
6. Bartz R, Firsching R, Rima B, ter Meulen V, Schneider-Schaulies J (1998). Differential receptor usage by measles virus strains. J Gen Virol 79: 1015 - 1025.
7. Bass BL, Weintraub H, Cattaneo R, Billeter MA (1989). Biased hypermutation of viral genomes could be due to the unwinding/modification of the double stranded RNA. Cell 56: 331.
8. Blixenkrone-Møller M, Bernard A, Bencsik A, Sixt N, Diamond LE, Logan JS and Wild TF (1998). Role of CD46 in measles virus infection in CD46 transgenic mice Virology 249: 238 - 248.
9. Brankin B, Hart MN, Cosby SL, Fabry Z, Allen IV (1995). Adhesion molecule expression and lymphocyte adhesion to cerebral endothelium: effects of measles virus and herpes simplex 1 virus. J Neuroimmunol 56: 1 - 8.
10. Cathomen T, Mrkic B, Spehner D, Drillien R, Naef R, Pavlovic J, Aguzzi A, Billeter MA, Cattaneo R (1998a). A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain. EMBO J 17: 3899 - 3908.
11. Cathomen T, Naim HY, Cattaneo R (1998b). Measles viruses with altered envelope protein cytoplasmic tails gain cell fusion competence. J Virol 72: 1224 - 1234.
12. Cattaneo R, Rebmann G, Schmid A, Baczko K, ter Meulen V, Billeter MA (1987a). Altered transcription of a defective measles virus genome derived from a diseased human brain. EMBO J 6: 681 - 687.
13. Cattaneo R, Rebmann G, Baczko K, ter Meulen V, Billeter MA (1987b). Altered Ratios of measles virus transcripts in diseased human brains. Virology 160: 523 - 526.
14. Cattaneo R, Schmid A, Eschle D, Baczko K, ter Meulen V, Billeter MA (1988). Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell 55: 255 - 265.
15. Cattaneo R, Schmid A, Spielhofer P, Kaelin K, Baczko K, ter Meulen V, Pardowitz J, Flanagan S, Rima BK, Udem SA, Billeter MA (1989). Mutated and hypermutated genes of persistent measles viruses which caused lethal human brain diseases. Virology 173: 415 - 425.
16. Cosby SL, Brankin B (1995). Measles virus infection of cerebral endothelial cells and effect on their adhesive properties. Vet Microbiol 44: 135 - 139.
17. Dhib-Jalbut S, Cowan EP (1993). Direct evidence that interferon-beta mediates enhanced HLA-class I expression in measles virus-infected cells. J Immunol 151: 1 - 11.
18. Dhib-Jalbut S, Xia J, Rangaviggula H, Fang Y-Y, Lee T (1999). Failure of measles virus to activate nuclear factor-κB in neuronal cells: implications on the immune response to viral infections in the central nervous system. J Immunol 162: 4024 - 4029.
19. Dörig RE, Marcil A, Chopra A, Richardson CD (1993). The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 75: 295 - 305.
20. Dörries R, Liebert UG, ter Meulen V (1988). Comparative analysis of virus-specific antibodies and immunoglobulins in serum and cerebrospinal fluid of subacute measles virus induced encephalomyelitis (SAM) in rats and subacute sclerosing panencephalitis (SSPE). J Neuroimmunol 19: 339 - 352.
21. Dörries R, ter Meulen V (1984). Detection and identification of virus-specific oligoclonal IgG in unconcentrated cerebrospinal fluid by immunoblot technique. J Neuroimmunol 7: 77 - 89.
22. Dörries R, Schwender S, Imrich H, Harms H (1991). Population dynamics of lymphocyte subsets in the central nervous system of rats with different susceptibility to coronavirus-induced demyelinating encephalitis. Immunology 74: 539 - 545.
23. Duclos P, Ward BJ (1998). Measles vaccines, a review of adverse events. Drug Safety, Dec. 19 6: 435 - 454.
24. Duprex P, Duffy I, McQuaid S, Hamill L, Schneider-Schaulies J, Cosby L, Billeter M, ter Meulen V (1999). The H gene of rodent brain-adapted measles virus confers neurovirulence to the Edmonston vaccine strain. J Virol 73: ???? - ????.
25. Ecker A, ter Meulen V, Baczko K, Schneider-Schaulies S (1995). Measles virus specific dsRNAs are targets for unwinding/modifying activity in neural cells in vitro. J Neurovirol 1: 92 - 100.
26. Esiri MM, Oppenheimer DR, Brownell B, Haire M (1981). Distribution of measles antigen and immunoglobulin containing cells in the CNS in subacute sclerosing panencephalitis (SSPE) and atypical measles. J Neurol Sci 53: 29 - 43.
27. Finke D, Brinckmann UG, ter Meulen V, Liebert UG (1995). Gamma Interferon is a major mediator of antiviral defense in experimental measles virus-induced encephalitis. J Virol 69: 5469 - 5474.
28. Finke D, Liebert UG (1994). CD4+ T cells are essential in overcoming experimental murine measles encephalitis. Immunology 83: 184 - 189.
29. Fujinami RS, Oldstone MBA (1980). Alterations in expression of measles virus polypeptides by antibody: molecular events in antibody induced antigenic modulation. J Immunol 125: 78 - 85.
30. Ghali M, Schneider-Schaulies J (1998). Receptor (CD46) and replication mediated Interleukin-6 induction by measles virus in human astrocytoma cells. J Neurovirol 4: 521 - 530.
31. Gogate N, Bakhiet M, Kristensson K, Norrby E, Olsson T (1991). Gamma-interferon expression and major histocompatibility complex induction during measles and vesicular stomatitis virus infections of the brain. J Neuroimmunol 31: 19 - 26.
32. Gogate N, Swoveland P, Yamabe T, Verma L, Woyciechowska J, Tarnowska-Dziduszko E, Dymecki J, Dhib-Jalbut S (1996). Major histocompatibility complex class I expression on neurons in subacute sclerosing panencephalitis and experimental subacute measles encephalitis. J Neuropathol Exp Neurol 55: 435 - 443.
33. Griffin D, Bellini WJ (1996). Measles virus. In: Fields Virology, Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Straus SE. (eds). Lippincott Raven Publishers, pp 1267 - 1312.
34. Hofman FM, Hinton DR, Baemayr J, Weil M, Merrill JE (1991). Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis. Clin Immunol Immunopathol 58: 331 - 342.
35. Horisberger MA (1992). Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins. J Virol 66: 4705 - 4709.
36. Horvat B, Rivailler P, Varior-Krishnan G, Cardoso A, Gerlier D, Rabourdin-Combe C (1996). Transgenic mice expressing human measles virus (MV) receptor CD46 provide cells exhibiting different permissivities to MV infections. J Virol 70: 6673 - 6681.
37. Hsu EC, Sarangi F, Iorio C, Sidhu MS, Udem SA, Dillehay DL, Xu W, Rota P, Bellini WJ, Richardson CD (1998). A single amino acid change in the hemagglutinin protein of measles virus determines its ability to bind CD46 and reveals another receptor on marmoset B cells. J Virol 72: 2905 - 2916.
38. Imrich H, Schwender S, Hein A, Dörries R (1994). Cervical lymphoid tissue but not the central nervous system supports proliferation of virus-specific T lymphocytes during coronavirus-induced encephalitis in rats. J Neuroimmunol 53: 73 - 81.
39. Johnson RT, Griffin DE, Hirsch RL, Wolinsky JS, Roedenbeck S, Soriano SL, Vaisberg A (1984). Measles encephalomyelitis - clinical and immunological studies. N Engl J Med 310: 137 - 141.
40. Joncas JH, Robillard LR, Boudreault A, Leyritz M, McLaughlin BJM (1976). Interferon in serum and cerebrospinal fluid in subacute sclerosing panencephalitis. Can Med Assoc J 115: 309.
41. Joseph BS, Oldstone MBA (1975). Immunological injury in measles virus infection II. Suppression of immune injury through antigenic modulation. J Exp Med 142: 864 - 876.
42. Kirk J, Zhou AL, McQuaid S, Cosby SL, Allen IV (1991). Cerebral endothelial cell infection by measles virus in subacute sclerosing panencephalitis: ultrastructural and in situ hybridization evidence. Neuropathol Appl Neurobiol 17: 289 - 297.
43. Kraus E, Schneider-Schaulies S, Miyasaka M, Tamatani T, Sedgwick J (1992). Augmentation of major histokompatibility complex class I and ICAM-1 expression on glial cells following measles virus infection: evidence for the role of type-1 Interferon. Eur J Immunol 22: 175 - 182.
44. Leopardi R, Vanionpää R, Hurme M, Siljander P, Salmi A (1992). Measles virus infection enhances IL-1ß but reduces tumor necrosis factor-a expression in human monocytes. J Immunol 149: 2397 - 2401.
45. Liebert UG, Baczko K, Budka H, ter Meulen V (1986). Restricted expression of measles virus proteins in brains from cases of subacute sclerosing panencephalitis. J Gen Virol 67: 2435 - 2444.
46. Liebert UG, Flanagan SG, Löffler S, Baczko K, ter Meulen V, Rima B (1994). Antigenic determinants of measles virus hemagglutinin associated with neurovirulence. J Virol 68: 1486 - 1493.
47. Liebert UG, ter Meulen V (1987). Virological aspects of measles virus induced encephalomyelitis in Lewis and BN rats. J Gen Virol 68: 1715 - 1722.
48. Liebert UG, Schneider-Schaulies S, Baczko K, ter Meulen V (1990). Antibody-induced restriction of viral gene expression in measles encephalitis in rats. J Virol 64: 706 - 713.
49. Liszweski MK, Post TW, Atkinson JP (1991). Membrane cofactor protein (MCP or CD46): Newest member of the regulators of complement activation gene cluster. Ann Rev Immunol 9: 431 - 455.
50. Massa PT, Schimpl A, Wecker E, ter Meulen V (1987). Tumor necrosis factor amplifies measles virus mediated Ia induction on astrocytes. Proc Natl Acad Sci USA 84: 7242 - 7245.
51. McQuaid S, Campbell R, Isserte S, Cosby SL (1997a). Leukaemia inhibitory factor mRNA is expressed in the brains of patients with subacute sclerosing panencephalitis. J Neuroimmunol 77: 57 - 62.
52. McQuaid S, Campbell S, Wallace IJC, Kirk J, Cosby SL (1998). Measles virus infection and replication in undifferentiated and differentiated human neuronal cells in culture. J Virol 72: 5245 - 5250.
53. McQuaid S, McMahon J, Herron B, Cosby SL (1997b). Apoptosis in measles virus-infected human central nervous system tissues. Neuropathol Appl Neurobiol 23: 218 - 224.
54. Meissner NN and Koschel K (1995). Downregulation of endothelin receptor mRNA synthesis in C6 rat astrocytoma cells by persistent measles virus and canine distemper virus infections. J. Virol. 69: 5191 - 5194.
55. Mesquita R, Castanos-Velez E, Biberfeld P, Troian RM, de Siqueira MM (1998). Measles virus antigen in macrophage/microglial cells and astrocytes of subacute sclerosing panencephalitis. APMIS 106: 553 - 561.
56. Metha PD, Patrick BA, Thormar H, Wiesniewski HM (1982). Oligoclonal IgG bands with and without measles antibody activity in sera of patients with aubacute sclerosing panencephalitis (SSPE). J Immunol 129: 1983 - 1985.
57. Metha PD, Thormar H, Kulczycki J, Wisniewski HM (1994). Immune response in subacute sclerosing panencephalitis. Ann NY Acad Sci 724: 378 - 384.
58. Meulen ter V, Carter MJ (1982). Morbillivirus persistent infections in animals and man. Virus Persistence Symposium 33, eels: Mahy BWJ, Minson AC, and Darby GK pp 97 - 132.
59. Miller CA, Carrigan DR (1982). Reversible repression and activation of measles virus infection in neural cells. Proc Natl Acad Sci USA 79: 1629 - 1633.
60. Mrkic B, Pavlovic J, Rülicke T, Volpe P, Buchholz CJ, Hourcade D, Atkinson JP, Aguzzi A, Cattaneo R (1998). Measles virus spread and pathogenesis in genetically modified mice. J Virol 72: 7420 - 7427.
61. Nagano I, Nakamura S, Yoshioka M, Kogure K (1991). Immunocytochemical analysis of the cellular infiltrate in brain lesions in subacute sclerosing panencephalitis. Neurology 41: 1639 - 1642.
62. Nagano I, Nakamura S, Yoshioka M, Onodera J, Kogure K, Itoyama Y (1994). Expression of cytokines in brain lesions in subacute sclerosing panencephalitis. Neurology 44: 710 - 715.
63. Naniche D, Varior-Krishnan G, Cervoni F, Wild TF, Rossi B, Rabourdin-Combe C, Gerlier D (1993). Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus. J Virol 67: 6025 - 13032.
64. Neumeister C, Niewiesk S (1998). Recognition of measles virus-infected cells by CD8+ T cells depends on the H-2 molecule. J Gen Virol 79: 2583 - 2591.
65. Niewiesk S, Brinckmann U, Bankamp B, Sirak S, Liebert UG, ter Meulen V (1993). Suceptibility to measles virus-induced encephalitis in mice correlates with impaired antigen presentation to cytotoxic T lymphocytes. J Virol 67: 75 - 81.
66. Niewiesk S, Schneider-Schaulies J, Ohnimus H, Jassoy C, Schneider-Schaulies S, Diamond L, Logan S, ter Meulen V (1997). CD46 expression does not overcome the intracellular block of measles virus replication in transgenic rats. J Virol 71: 7969 - 7973.
67. Norrby E, Kristensson K (1997). Measles virus in the brain. Brain Res Bulletin 44: 213 - 220.
68. Ogata A, Czub S, Ogata S, Cosby SL, McQuaid S, Budka H, ter Meulen V, Schneider-Schaulies J (1997). Absence of measles virus receptor (CD46) in lesions of subacute sclerosing panencephalitis brains. Acta Neuropathol 94: 444 - 449.
69. Ogata S, Ogata A, Schneider-Schaulies S, Iwasaki Y, ter Meulen V, Schneider-Schaulies J (1999). Expression of the interferon-α/β-inducible MxA protein in and around lesions of subacute sclerosing panencephalitis (SSPE) brains. Submitted for publication.
70. Ogura H, Baczko K, Rima BK, ter Meulen V (1987). Selective inhibition of translation of the mRNA coding for the measles virus membrane protein at elevated temperatures. J Virol 61: 472 - 479.
71. Ogura H, Rima BK, Baczko K, ter Meulen V (1988). Restricted synthesis of the fusion protein of Measles Virus at elevated temperatures. J Gen Virol 69: 925 - 929.
72. Pavlovic J, Zürcher T, Haller O, Staeheli P (1990). Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein. J Virol 64: 3370 - 3375.
73. Pitossi F, Blank A, Schröder A, Schwarz A, Hüssi P, Schwemmle M, Pavlovic J, Staeheli P (1993). A functional GTP binding motif is necessary for antiviral activity of mx proteins. J Virol 67: 6726 - 6732.
74. Radecke F, Spielhofer P, Schneider H, Kaelin K, Huber M, Dötsch C, Christiansen G, Billeter MA (1995). Rescue of measles viruses from cloned DNA. EMBO J 14: 5773 - 5784.
75. Rail GF, Manchester M, Daniels LR, Callahan EM, Belman AR, Oldstone MBA (1997). A transgenic mouse model for measles virus infection of the brain. Proc Natl Acad Sci USA 94: 4659 - 4663.
76. Rataul SM, Hirano A, Wong TC (1992). Irreversible modification of measles virus RNA in vitro by nuclear RNA-unwinding activity in human neuroblastoma cells. J Virol 66: 1769 - 1773.
77. Reich A, Erlwein O, Niewiesk S, ter Meulen V, Liebert UG (1992). CD4+ T cells control measles virus infection of the central nervous system. Immunology 76: 185 - 191.
78. Rima BK, Earle JAP, Baczko K, ter Meulen V, Liebert UG, Carstens C, Carabana J, Caballero M, Celma NL, Fernandez-Monoz R (1997). Sequence divergence of measles virus haemagglutinin during natural evolution and adaptation to cell culture. J Gen Virol 78: 97 - 106.
79. Rima BK, Earle JAP, Yeo RP, Herlihy L, Baczko K, ter Meulen V, Carabana J, Caballero M, Celma ML, Fernandez-Munoz R (1995). Temporal and geographical distribution of measles virus genotypes. J Gen Virol 76: 1173 - 1180.
80. Rota JS, Rota P, Redd SB, Redd SC, Pattamadilok S, Bellini WJ (1998). Genetic analysis of measles viruses isolated in the United States, 1995-1996. J Inf Dis 177: 204 - 208.
81. Schmid A, Spielhofer P, Cattaneo R, Baczko K, ter Meulen V, Billeter MA (1992). Subacute sclerosing panencephalitis is typically characterized by alterations in the fusion protein cytoplasmic domain of the persisting measles virus. Virology 188: 910 - 915.
82. Schneider-Schaulies J, Liebert UG, Dörries R, ter Meulen V (1997). Establishment and control of viral infections of the central nervous system. In: Immunology of the nervous system. Keane RW and Hickey WF, (eds). Oxford University Press, pp 576 - 610.
83. Schneider-Schaulies J, Schneider-Schaulies S, ter Meulen V (1993b). Differential induction of cytokines by primary and persistent measles virus infections in human glial cells. Virology 195: 219 - 228.
84. Schneider-Schaulies J, Schnorr JJ, Schlender J, Dunster LM, Schneider-Schaulies S, ter Meulen V (1996). Receptor (CD46) modulation and complement mediated lysis of uninfected cells after contact with measles virus-infected cells. J Virol 70: 255 - 263.
85. Schneider-Schaulies S, Liebert UG, Baczko K, Cattaneo R, Billeter M, ter Meulen V (1989). Restriction of measles virus gene expression in acute and subacute encephalitis of Lewis rats. Virology 171: 525 - 534.
86. Schneider-Schaulies S, Liebert UG, Baczko K, ter Meulen V (1990). Restricted expression of measles virus in primary rat astroglial cells. Virology 177: 802 - 806.
87. Schneider-Schaulies S, Liebert UG, Segev Y, Rager-Zisman B, Wolfson M, ter Meulen V (1992). Antibody-dependent transcriptional regulation of measles virus in persistently infected neural cells. J Virol 66: 5534 - 5541.
88. Schneider-Schaulies S, Niewiesk S, ter Meulen V (1999). Measles virus. In: Persistent Viral Infections. Ahmed R and Chen ISY (eds). John Wiley & Sons, pp 297 - 320.
89. Schneider-Schaulies S, Schneider-Schaulies J, Bayer M, Löffler S, ter Meulen V (1993a). Spontaneous and differentiation dependent regulation of measles virus gene expression in human glial cells. J Virol 67: 3375 - 3383.
90. Schneider-Schaulies S, Schneider-Schaulies J, Schuster A, Bayer M, Pavlovic J, ter Meulen V (1994). Cell type specific MxA-mediated inhibition of measles virus transcription in human brain cells. J Virol 68: 6910 - 6917.
91. Schnorr JJ, Schneider-Schaulies S, Simon-Jödicke A, Pavlovic J, Horisberger MA, ter Meulen V (1993). MxA dependent inhibition of measles virus glycoprotein synthesis in a stably transfected human monocytic cell line. J Virol 67: 4760 - 4768.
92. Schnorr JJ, Dunster LM, Nanan R, Schneider-Schaulies J, Schneider-Schaulies S, ter Meulen V (1995). Measles virus induced downregulation of CD46 is associated with enhanced sensitivity to complement mediated lysis of infected cells. Eur J Immunol 25: 976 - 984.
93. Staeheli P (1990). Interferon induced proteins and the antiviral state. Adv Virus Res 38: 147 - 200.
94. Staeheli P, Pavlovic J (1992). Inhibition of vesicular stomatitis virus mRNA synthesis by human MxA protein. J Virol 65: 4498 - 4501.
95. Stohlman SA, Bergmann CC, Lin MT, Cua MT, Hinton DR (1998). CTL effector function within the central nervous system requires CD4+ T cells, J Immunol 160: 2896 - 2904.
96. Tamin A, Rota P, Wang Zd, Heath JL, Anderson LJ, Bellini WJ (1994). Antigenic analysis of current wilde type and vaccine strains of measles virus. J Inf Dis 170: 795 - 801.
97. Tanaka K, Xie M, Yanagi Y (1998). The hemagglutinin of recent measles virus isolates induces cell fusion in a marmoset cell line, but not in other CD46-positive human and monkey cell lines, when expressed together with the F protein. Arch Virol 143: 213 - 225.
98. Urbanska EM, Chambers BJ, Ljunggren HG, Norrby E, Kristensson K (1997). Spread of measels virus through axonal pathways into limbic structures in the brain of TAP - / - mice. J Med Virol 52: 362 - 369.
99. Vandvik B, Norrby E (1973). Oligoclonal IgG antibody response in the central nervous system to different measles virus antigens in subacute sclerosing panencephalitis. Proc Natl Acad Sci USA 70: 1060 - 1063.
100. Wong GHW, Bartlett PF, clark-Lewis I, McKimm-Breschkin JL, Schrader JW (1985). Interferon-g induces the expression of H-2 and Ia antigens on brain cells. J Neuroimmunol 7: 255 - 278.
101. Yoshikawa Y, Yamanouchi K (1984). Effects of papaverine treatment on replication of measles virus in human neural and non-neural cells. J Virol 50: 489 - 495.
102. Zimmermann C, Seiler P, Lane P, Zinkernagel RM (1997). Antiviral immune responses in CTLA4 transgenic mice. J Virol 71: 1802 - 1807.